WO2013067836A1 - 一体式混药接口 - Google Patents

一体式混药接口 Download PDF

Info

Publication number
WO2013067836A1
WO2013067836A1 PCT/CN2012/079560 CN2012079560W WO2013067836A1 WO 2013067836 A1 WO2013067836 A1 WO 2013067836A1 CN 2012079560 W CN2012079560 W CN 2012079560W WO 2013067836 A1 WO2013067836 A1 WO 2013067836A1
Authority
WO
WIPO (PCT)
Prior art keywords
interface
mixing
mixed
base
integrated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2012/079560
Other languages
English (en)
French (fr)
Inventor
邱宇
李科
袁媛
李鸿宇
周兵
赵柳英
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chongqing Lummy Pharmaceutical Co Ltd
Original Assignee
Chongqing Lummy Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN2011103570484A external-priority patent/CN102499888B/zh
Priority claimed from CN201220173737XU external-priority patent/CN202505776U/zh
Application filed by Chongqing Lummy Pharmaceutical Co Ltd filed Critical Chongqing Lummy Pharmaceutical Co Ltd
Priority to CA2877510A priority Critical patent/CA2877510C/en
Priority to US14/415,131 priority patent/US9775778B2/en
Priority to EP12847291.7A priority patent/EP2881101B1/en
Publication of WO2013067836A1 publication Critical patent/WO2013067836A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1475—Inlet or outlet ports
    • A61J1/1481—Inlet or outlet ports with connection retaining means, e.g. thread or snap-fit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions

Definitions

  • the invention relates to a medical device, in particular to a hard dual interface with a mixing nozzle.
  • the hard dual interface with the mixing nozzle mainly comprises a base, a mixed card body, a syringe body, a hose, an easy folding handle and a medicated needle.
  • the base has a mixed drug interface and an infusion interface, and the mixed drug interface extends out of the base and has a cylindrical hollow structure; the infusion interface extends out of the base and has a cylindrical hollow structure.
  • the mixed drug card body is a cylindrical hollow structure, and the medicinal needle is disposed in the mixed drug card body, and the lower end surface of the mixed drug card body is sealed with the outer wall of the medicated needle, and the needle cylinder body is located at the lower end surface of the mixed drug card body.
  • the easy-to-fold handle is installed in the hose, and the passage between the medicated needle and the mixed drug interface is mainly blocked. When mixing the medicine, the easy-folding handle needs to be broken to connect the passage between the medicated needle and the mixed medicine interface.
  • the above hard double interface with a mixed nozzle mainly has the following disadvantages: 1.
  • the mixed drug interface on the mixed nozzle and the hard double interface needs to be connected through a hose, and one end of the hose is placed on the mixed interface of the hard double interface, and Welding with the mixed drug interface, the other end of the hose is sleeved on the syringe body and welded to the syringe body, thereby increasing the installation position of the hose and increasing the welding position, thereby increasing the welding The probability of leakage of the part during mixing;
  • Second, the mixing nozzle is connected to the mixed interface on the hard double interface through the hose.
  • the temperature is low (such as the temperature below zero), which is easy to cause
  • the welded part of the hose is cracked, which leads to the leakage of the mixed drug. 3.
  • the mixing nozzle of the above structure is connected with the mixing interface of the hard double interface through the hose, and the easy-folding handle is also installed in the hose, which increases Process difficulty and working hours, and at the same time, it is very likely to reduce the product qualification rate.
  • the present invention provides an integrated mixed drug interface that does not require the use of an easy-to-fold handle and a hose to avoid mixing and leakage due to welding, and has a simple structure and low cost.
  • the present invention adopts the following technical solutions:
  • the integrated mixed drug interface comprises a mixing nozzle, a hard double interface and a medicating needle.
  • the hard dual interface comprises a base, a mixing interface and an infusion interface, and the mixing nozzle is integrally formed with the mixing interface.
  • the medicated needle is a cross pin, and an inner surface of the mixed drug channel integrally formed by the mixing nozzle and the mixed drug interface is provided with an annular rubber pad I, and the lower portion of the cross pin is stuck In the inner hole of the annular rubber pad I, the base of the cross pin is located in the mixing card body of the mixing nozzle.
  • a membrane for sealing the mixed drug passage is provided in the mixed drug interface.
  • the outer wall of the base is uniformly provided with a weld pattern.
  • both ends of the base extend outward to form a sheet having a gradually thinner thickness.
  • the mixed drug body of the mixing nozzle is a cylindrical hollow structure, and at least two barbed shapes are symmetrically disposed on the inner wall of the mixed drug body, and are used for preventing drugs.
  • the container has a loose anti-slip buckle.
  • a sealing cover is provided at the upper end of the mixed cartridge body of the mixing nozzle.
  • annular rubber pad II is disposed in the mixing card body and above the base of the medicated needle, and the annular rubber pad II is sleeved outside the medicated needle.
  • the annular rubber pad II is located between the base and the cleat.
  • the utility model has the beneficial effects that: when the integrated mixed drug interface is used, only the base is welded on the bag body of the infusion soft bag, and the mixed drug mouth and the mixed drug interface on the hard double interface are integrally formed, and no hose is needed.
  • the connection and easy folding handle not only reduce the hose installation position, but also avoid the leakage of the weld seam caused by the hose welding defects, and the structure is simple and the cost is low.
  • Figure 1 is a schematic structural view of an integrated mixed drug interface
  • FIG. 2 is a schematic structural view of a mixed nozzle and a hard double interface
  • Figure 3 is a schematic structural view of a medicated needle
  • Figure 4 is a schematic view of the structure of the integrated mixed drug interface before use
  • Figure 5 is a schematic view showing the structure of the integrated mixed drug interface in use.
  • the integrated mixing interface includes a mixing nozzle 1, a hard double interface 2, and a medicating needle 3.
  • the hard dual interface 2 includes a base 21, a mixing interface 22 and an infusion interface 23, and the mixing nozzle 1 and the mixing interface 22 are integrally formed.
  • the medicated needle 3 is a cross needle (that is, the medicated double needle, the cutting plane along the axis of the medicating needle is a "cross" structure), and the upper and lower needle tips of the medicated needle 3 are both conical structures, and three pinholes are evenly distributed.
  • the inner wall of the mixing passage integrally formed with the mixing nozzle 1 and the mixing interface 22 is provided with an annular rubber pad I4, the lower portion of the cross pin is stuck in the inner hole of the annular rubber pad I4, and the base 5 of the cross pin is located at the mixing nozzle 1
  • the mixed drug body 6 is inside.
  • a diaphragm 14 for sealing the mixed drug passage is disposed in the mixing interface 22, and the base 21 of the hard dual interface 2 is welded to the infusion soft bag 11, and before the mixing is performed (as shown in FIG. 4), the diaphragm 14 can be The mixed drug passage is blocked, and the infusion solvent in the infusion soft bag 11 is kept sealed without contact with the medicated needle 3, and the infusion solvent is prevented from being poured into the mixed drug body 6 through the medicated needle 3, thereby causing leakage, which is strict The volume of the infusion solvent in the infusion soft bag 11 is ensured to avoid the pollution before use; when the medicated needle 3 punctures the membrane 14, the mixed drug interface 22 and the medicated needle 3 are connected, so that the infusion solvent can flow into the drug container.
  • the annular rubber pad I4 replaces the diaphragm 14, which not only blocks the infusion solvent from contacting the outside, but also restricts the infusion solution to flow into the drug container 12 only through the medicated needle 3. Therefore, the arrangement of the diaphragm 14 strictly controls the opening sequence of the mixing passage, thereby ensuring the safety and hygiene of the mixing process.
  • the diaphragm 14 can be integrally formed with the mixing interface 22, the process is simple, easy to implement, and the material cost is low, and the economic burden of the consumer is not increased.
  • the outer wall of the base 21 is uniformly provided with a weld pattern 7 (in the present embodiment, four weld lines are uniformly disposed on the outer wall of the base 21).
  • the projection of the base 21 in its cross section is a boat-shaped structure, and extends outwardly at both ends of the base 21 of the boat-shaped structure to form a sheet 8 of gradually thinner thickness.
  • the base 21 is more firmly welded to the pocket of the infusion soft bag 11 through the welding line 7 thereon, and the sealing effect of the base 21 and the infusion soft bag 11 is better; and the sheet 8 on both sides of the base 21 and the infusion
  • the bag mouth of the soft bag 11 can be quickly integrated into one body, which not only accelerates the welding speed, but also enhances the sealing effect of the base 21 and the infusion soft bag 11.
  • the mixed cartridge body 6 has a cylindrical hollow structure, and at least two anti-slip fasteners 9 are provided symmetrically on the inner wall of the mixed cartridge body 6 for preventing the looseness of the drug container.
  • six anti-slip buckles 9 are symmetrically disposed on the inner wall of the hybrid card body 6. After the drug container 12 is inserted into the drug-filled card body 6, the drug container can effectively prevent the drug container 12 from being withdrawn or loosened in the opposite direction in the drug-filled card body 6 under the obstruction of the anti-slip buckle 9.
  • a sealing cover 10 is provided at the upper end of the mixed cartridge body 6. Before use, the sealing cover 10 not only seals the mixed card body 6, the medicated needle 3 located in the mixed drug card body 6, and the mixed drug channel in the hard double interface 2, so that the mixed drug body 6 is located in the mixed drug.
  • the medicated needle 3 in the card body 6 and the mixed drug passage in the hard double interface 2 have good cleanliness before use, and also effectively protect the sharpness of the needle on the medicated needle and the inside of the mixed cartridge body 6.
  • the structure avoids damage during transportation; when used, the sealing cover 10 can be removed, which is convenient, and can ensure the mixed medicine body 6, the medicated needle 3 located in the mixed drug body 6, and the hard double interface 2 The cleanliness of the mixed channel.
  • An annular rubber pad II13 is disposed in the mixed drug body 6 and above the base 5 of the medicated needle 3.
  • the annular rubber pad II13 is sleeved outside the medicating needle 3.
  • the annular rubber pad II13 is located at the base 5 and the anti-slip buckle 9. between.
  • An annular rubber pad II13 sleeved on the outer side of the medicated needle 3 is provided above the susceptor 5 of the medicated needle 3, and the annular rubber pad II13 has good elasticity and is inserted in the drug container 12.
  • the loop rubber pad II13 and the anti-slip buckle 9 on the mixed cartridge body 6 can effectively prevent the drug container 12 from loosening, and the annular rubber pad II13 completely seals the drug container 12 with
  • the insertion site between the mixed card bodies 6 avoids the leakage of the liquid medicine during the mixed medicine, and the absolute airtightness in the drug container after the mixed medicine can be strictly ensured, so as to prevent the danger of the bacteria.
  • the base 21 is welded to the pocket of the infusion soft bag 11, and the bottom of the medicating needle is caught in the inner hole of the annular rubber pad I4.
  • the sealing cap 10 is removed, the drug container 12 is snapped into the mixed cartridge body 6, and then the drug container 12 is pushed downward so that the top of the medicating needle 3 is piercing the sealing plug on the drug container 12, The medicated needle 3 is also pushed downward, so that the bottom of the medicating needle 3 pierces the septum 14 in the mixing port 22, and the pedestal 5 of the medicating needle 3 is finally moved to the bottom of the mixed cartridge body 6, so that The drug container 12 is in communication with the infusion soft bag 11, as shown in FIG.

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

一种一体式混药接口，包括混药嘴（1）、硬双接口（2）和加药针（3），硬双接口（2）包括底座（21）、混药接口（22）和输液接口（23），混药嘴（1）与混药接口（22）一体成型。使用该一体式混药接口时，只需将底座（21）焊合在输液软袋（11）的袋体上，混药嘴（1）与硬双接口（2）上的混药接口一体成型，无需采用软管连接和易折柄，既减少了软管安装工位，又避免了因软管焊接缺陷所带来的焊缝漏液，且结构简单，成本低。

Description

一体式混药接口
技术领域
本发明涉及一种医疗器械，尤其涉及一种带混药嘴的硬双接口。
背景技术
在临床治疗疾病中，常给病人输液或者通过静脉滴注直接将药物注入体内，药物常存储在输液软袋内，而输液软袋内的药液注入或输出常常通过带混药嘴的硬双接口实现。
现有技术中，带混药嘴的硬双接口主要包括底座、混药卡体、针筒体、软管、易折柄和加药针。底座上具有一混药接口和一输液接口，混药接口延伸出底座，且为圆柱状中空结构；输液接口延伸出基座，且为圆柱状中空结构。混药卡体为圆柱状中空结构，加药针设在混药卡体内，混药卡体的下端面与加药针外壁密封，针筒体位于混药卡体的下端面。软管的一端套在混药接口上，并与该混药接口焊合，软管的另一端套在针筒体上，并与该针筒体焊合。易折柄安装在软管内，主要将加药针和混药接口之间的通道堵塞，混药时，需将易折柄折断，才能将加药针和混药接口之间的通道连通。
上述带混药嘴的硬双接口主要存在如下不足：一、混药嘴与硬双接口上的混药接口需通过软管连接，软管的一端套在硬双接口的混药接口上，并与该混药接口焊合，软管的另一端套在针筒体上，并与该针筒体焊合，这样既增加了软管的安装工位，又增加焊接部位，增大了因焊接部位在混药时漏液的几率；二、混药嘴通过软管与硬双接口上的混药接口连接，因软管所采用材料的限制，在温度较低（如零下温度），易导致软管的焊接部位开裂，进而导致混药漏液；三、上述结构的混药嘴，通过软管与硬双接口上的混药接口连接时，软管内还需安装易折柄，增加了工艺难度和工时，同时又极可能降低产品合格率。
发明内容
针对现有技术中存在的上述不足，本发明提供了一种无需采用易折柄和软管，避免因焊接而产生混药漏液，且结构简单，成本低的一体式混药接口。
为了解决上述技术问题，本发明采用了如下技术方案：
一体式混药接口，包括混药嘴、硬双接口和加药针，所述硬双接口包括底座、混药接口和输液接口，所述混药嘴与混药接口一体成型。
作为本发明的一种优选方案，所述加药针为十字针，所述混药嘴与混药接口一体成型的混药通道的内壁设有环形胶垫Ⅰ，所述十字针的下部卡在环形胶垫Ⅰ的内孔中，所述十字针的基座位于混药嘴的混药卡体内。
作为本发明的另一种优选方案，所述混药接口内设有一用于密封混药通道的隔膜。
作为本发明的又一种优选方案，所述底座的外壁上均布设有焊接纹路。
作为本发明的一种改进方案，所述底座的两端向外延伸形成厚度逐渐变薄的薄片。
作为本发明的另一种改进方案，所述混药嘴的混药卡体为圆柱状中空结构，在混药卡体的内壁上对称设置有至少两个呈倒钩状、且用于防止药物容器松动的防滑扣。
作为本发明的又一种改进方案，在混药嘴的混药卡体的上端设有密封盖。
作为本发明的进一步改进方案，所述混药卡体内、且在加药针的基座上方设有环形胶垫Ⅱ，所述环形胶垫Ⅱ套在加药针外。
作为本发明的再进一步改进方案，所述环形胶垫Ⅱ位于基座和防滑扣之间。
本发明的有益效果是：使用该一体式混药接口时，只需将底座焊合在输液软袋的袋体上，混药嘴与硬双接口上的混药接口一体成型，无需采用软管连接和易折柄，既减少了软管安装工位，又避免了因软管焊接缺陷所带来的焊缝漏液，且结构简单，成本低。
附图说明
图1为一体式混药接口的结构示意图；
图2为混药嘴与硬双接口一体成型的结构示意图；
图3为加药针的结构示意图；
图4为一体式混药接口在使用前的结构示意图；
图5为一体式混药接口在使用时的结构示意图。
附图中：1—混药嘴； 2—硬双接口； 21—底座； 22—混药接口； 23—输液接口； 3—加药针； 4—环形胶垫Ⅰ； 5—基座； 6—混药卡体； 7—焊接纹路； 8—薄片； 9—防滑扣； 10—密封盖； 11—输液软袋； 12—药物容器； 13—环形胶垫Ⅱ； 14—隔膜。
具体实施方式
下面结合附图和具体实施方式对本发明作进一步详细地描述。
如图1、图2和图3所示，一体式混药接口，包括混药嘴1、硬双接口2和加药针3。硬双接口2包括底座21、混药接口22和输液接口23，混药嘴1与混药接口22一体成型。
加药针3为十字针（即加药双针，沿该加药针的轴线的剖切面为“十字”结构），加药针3的上下针尖均为圆锥结构，有三个针孔均布在该圆锥结构的锥面上。混药嘴1与混药接口22一体成型的混药通道的内壁设有环形胶垫Ⅰ4，十字针的下部卡在环形胶垫Ⅰ4的内孔中，十字针的基座5位于混药嘴1的混药卡体6内。混药接口22内设有一用于密封混药通道的隔膜14，在硬双接口2的底座21焊合在输液软袋11上，实施混药之前（如图4所示），该隔膜14可阻断混药通道，使输液软袋11中的输液溶剂保持密封而不与加药针3接触，避免输液溶剂通过加药针3灌入混药卡体6中，从而产生漏液，既严格的保证了输液软袋11中输液溶剂的体积又避免了使用前的污染；当加药针3穿刺隔膜14后，混药接口22和加药针3连通，从而使得输液溶剂可以流入药物容器实现混药（如图5所示），而此时环形胶垫Ⅰ4即替代了隔膜14，不但可阻隔输液溶剂与外界接触，还限制了输液溶液仅能通过加药针3流入药物容器12。所以此隔膜14的设置严格的控制了混药通道的打开顺序，保证了混药过程的安全卫生。另外，该隔膜14可与混药接口22一体成型，工艺简单，易实现，而且材料成本低，不会增加消费者的经济负担。
底座21的外壁上均布设有焊接纹路7（本实施例中，在底座21的外壁上均布设有四条焊接纹路）。底座21在其横截面的投影呈船形结构，且在该船形结构的底座21的两端向外延伸形成厚度逐渐变薄的薄片8。热焊接时，底座21通过其上的焊接纹路7与输液软袋11的袋口焊合更牢固，底座21与输液软袋11的密封效果更佳；而且，底座21两侧的薄片8与输液软袋11的袋口能快速融合为一体，既加快了焊合速度，又可增强底座21与输液软袋11的密封效果。
混药卡体6为圆柱状中空结构，在混药卡体6的内壁上对称设置有至少两个呈倒钩状、且用于防止药物容器松动的防滑扣9。本实施例中，在混药卡体6的内壁上对称设置有六个防滑扣9。在药物容器12卡入混药卡体6内后，药物容器在防滑扣9的阻碍作用下，可有效避免药物容器12在混药卡体6内向反方向退出或松动。
在混药卡体6的上端设有密封盖10。使用前，密封盖10不仅使混药卡体6、位于混药卡体6内的加药针3以及硬双接口2内的混药通道处于密封状态，使混药卡体6、位于混药卡体6内的加药针3以及硬双接口2内的混药通道在使用前具有良好的清洁度，还有效的保护了加药针上针的锋锐度和混药卡体6的内部结构，避免运输过程中的损坏；使用时，拆除密封盖10即可使用，既方便，又能保证混药卡体6、位于混药卡体6内的加药针3以及硬双接口2内的混药通道的清洁度。
混药卡体6内、且在加药针3的基座5上方设有环形胶垫Ⅱ13，环形胶垫Ⅱ13套在加药针3外，环形胶垫Ⅱ13位于基座5和防滑扣9之间。因混药卡体6内、且在加药针3的基座5上方设有套在加药针3外的环形胶垫Ⅱ13，该环形胶垫Ⅱ13具有良好的弹性，在药物容器12卡入混药卡体6内时（如图5所示），该环形胶垫Ⅱ13和混药卡体6上的防滑扣9可有效的防止药物容器12松动，环形胶垫Ⅱ13完全密封药物容器12与混药卡体6之间的插接位点，避免混药时发生药液渗漏，也可严格保证混药后的药物容器内的绝对气密性，杜绝染菌危险。
使用该一体式混药接口时，如图4所示，将底座21焊合在输液软袋11的袋口上，加药针的底部卡在环形胶垫Ⅰ4的内孔中。混药时，拆除密封盖10，将药物容器12卡入混药卡体6内，然后向下推动药物容器12，使加药针3的顶部在刺穿药物容器12上的密封塞的同时，也推动加药针3向下行，使加药针3的底部刺穿混药接口22内的隔膜14，并使加药针3的基座5最终移动到混药卡体6内的底部，这样药物容器12便与输液软袋11内实现了连通，如图5所示。
最后说明的是，以上实施例仅用以说明本发明的技术方案而非限制，尽管参照较佳实施例对本发明进行了详细说明，本领域的普通技术人员应当理解，可以对本发明的技术方案进行修改或者等同替换，而不脱离本发明技术方案的宗旨和范围，其均应涵盖在本发明的权利要求范围当中。

Claims (9)

  1. 一体式混药接口，包括混药嘴（1）、硬双接口（2）和加药针（3），所述硬双接口（2）包括底座（21）、混药接口（22）和输液接口（23），其特征在于：所述混药嘴（1）与混药接口（22）一体成型。
  2. 根据权利要求1所述的一体式混药接口，其特征在于：所述加药针（3）为十字针，所述混药嘴（1）与混药接口（22）一体成型的混药通道的内壁设有环形胶垫Ⅰ（4），所述十字针的下部卡在环形胶垫Ⅰ（4）的内孔中，所述十字针的基座（5）位于混药嘴（1）的混药卡体（6）内。
  3. 根据权利要求2所述的一体式混药接口，其特征在于：所述混药接口（22）内设有一用于密封混药通道的隔膜（14）。
  4. 根据权利要求1、2或3所述的一体式混药接口，其特征在于：所述底座（21）的外壁上均布设有焊接纹路（7）。
  5. 根据权利要求1、2或3所述的一体式混药接口，其特征在于：所述底座（21）的两端向外延伸形成厚度逐渐变薄的薄片（8）。
  6. 根据权利要求1、2或3所述的一体式混药接口，其特征在于：所述混药嘴（1）的混药卡体（6）为圆柱状中空结构，在混药卡体（6）的内壁上对称设置有至少两个呈倒钩状、且用于防止药物容器松动的防滑扣（9）。
  7. 根据权利要求1、2或3所述的一体式混药接口，其特征在于：在混药嘴（1）的混药卡体（6）的上端设有密封盖（10）。
  8. 根据权利要求2或3所述的一体式混药接口，其特征在于：所述混药卡体（6）内、且在加药针（3）的基座（5）上方设有环形胶垫Ⅱ（13），所述环形胶垫Ⅱ（13）套在加药针（3）外。
  9. 根据权利要求8所述的一体式混药接口，其特征在于：所述环形胶垫Ⅱ（13）位于基座（5）和防滑扣（9）之间。
PCT/CN2012/079560 2011-11-11 2012-08-02 一体式混药接口 Ceased WO2013067836A1 (zh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA2877510A CA2877510C (en) 2011-11-11 2012-08-02 Integrated medicine mixing interface
US14/415,131 US9775778B2 (en) 2011-11-11 2012-08-02 Integrated medicine mixing interface
EP12847291.7A EP2881101B1 (en) 2011-11-11 2012-08-02 Integrated medicine mixing interface

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN2011103570484A CN102499888B (zh) 2011-11-11 2011-11-11 一体成型的混药接口
CN201110357048.4 2011-11-11
CN201220173737.X 2012-04-23
CN201220173737XU CN202505776U (zh) 2012-04-23 2012-04-23 防止药物容器松动的硬双接口

Publications (1)

Publication Number Publication Date
WO2013067836A1 true WO2013067836A1 (zh) 2013-05-16

Family

ID=48288506

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2012/079560 Ceased WO2013067836A1 (zh) 2011-11-11 2012-08-02 一体式混药接口

Country Status (4)

Country Link
US (1) US9775778B2 (zh)
EP (1) EP2881101B1 (zh)
CA (1) CA2877510C (zh)
WO (1) WO2013067836A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2999449A1 (fr) * 2013-05-22 2016-03-30 Maco Pharma Embase d'un connecteur pour poche de perfusion

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3760180B1 (en) 2009-07-29 2024-10-30 ICU Medical, Inc. Fluid transfer devices
KR102481494B1 (ko) 2011-12-22 2022-12-26 아이씨유 메디칼 인코퍼레이티드 의료용 유체 전달 시스템, 유체 전달 방법, 전자 의료용 유체 전달 시스템, 및 전자 의료용 유체 전달 시스템 이용 방법
JP6259113B2 (ja) 2013-11-25 2018-01-10 アイシーユー・メディカル・インコーポレーテッド 点滴バッグに治療用流体を充填するための方法およびシステム
EP3375427B1 (en) * 2015-11-13 2023-06-21 Chongqing Lummy Pharmaceutical Co., Ltd. Drug mixer, hard dual-port member, and soft infusion bag
JP6710758B2 (ja) 2015-12-04 2020-06-17 アイシーユー・メディカル・インコーポレーテッド 医療用流体を移送するための電子式医療用流体移送装置
CN105997509A (zh) * 2016-07-18 2016-10-12 湖南懿科药用包装材料科技有限公司 可对多剂型进行多次直配的输液容器组合盖及输液容器
USD851745S1 (en) 2016-07-19 2019-06-18 Icu Medical, Inc. Medical fluid transfer system
WO2018022640A1 (en) 2016-07-25 2018-02-01 Icu Medical, Inc. Systems, methods, and components for trapping air bubbles in medical fluid transfer modules and systems
US11116696B2 (en) * 2017-08-10 2021-09-14 Baxter International Inc. Reconstitution device, system, and method to administer a drug in a moderate bolus
CN111150655A (zh) * 2020-01-10 2020-05-15 李涛 一种耳鼻喉治疗用混合给药装置
US11590057B2 (en) 2020-04-03 2023-02-28 Icu Medical, Inc. Systems, methods, and components for transferring medical fluids
AU2021356704A1 (en) 2020-10-09 2023-06-01 Icu Medical, Inc. Fluid transfer device and method of use for same

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05337163A (ja) * 1992-06-05 1993-12-21 Nissho Corp 連通手段を備えた輸液容器
JPH08141049A (ja) * 1994-11-22 1996-06-04 Material Eng Tech Lab Inc 薬剤の混合用連結部及びその連結部付き容器
CN2850611Y (zh) * 2005-11-03 2006-12-27 湖南乐福地医药包材科技有限公司 大输液软袋用带有穿刺功能的混药嘴的硬接口
CN2915101Y (zh) * 2006-04-14 2007-06-27 湖南千山制药机械股份有限公司 采用带保护套的混药嘴的硬接口输液袋
CN102499888A (zh) * 2011-11-11 2012-06-20 重庆莱美药业股份有限公司 一体成型的混药接口
CN202314384U (zh) * 2011-11-11 2012-07-11 重庆莱美药业股份有限公司 一体式混药接口

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304163A (en) 1990-01-29 1994-04-19 Baxter International Inc. Integral reconstitution device
JP3514505B2 (ja) 1994-04-12 2004-03-31 藤沢薬品工業株式会社 溶解液容器の製造方法
US20050137566A1 (en) 2003-12-23 2005-06-23 Fowles Thomas A. Sliding reconstitution device for a diluent container
CN2843445Y (zh) 2005-11-25 2006-12-06 湖南千山制药机械股份有限公司 带简易组合盖和带具有刺穿功能的混药嘴的硬接口输液袋
US7473246B2 (en) 2006-06-22 2009-01-06 Baxter International Inc. Medicant reconstitution container and system
DE102008060864A1 (de) * 2008-12-09 2010-06-10 Fresenius Kabi Deutschland Gmbh Verschlusskappe für Behältnisse zur Aufnahme von medizinischen Flüssigkeiten und Behältnis zur Aufnahme von medizinischen Flüssigkeiten
CN102178602B (zh) 2011-03-01 2013-02-06 重庆莱美药业股份有限公司 一种用于塑料输液软袋的混药接口

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05337163A (ja) * 1992-06-05 1993-12-21 Nissho Corp 連通手段を備えた輸液容器
JPH08141049A (ja) * 1994-11-22 1996-06-04 Material Eng Tech Lab Inc 薬剤の混合用連結部及びその連結部付き容器
CN2850611Y (zh) * 2005-11-03 2006-12-27 湖南乐福地医药包材科技有限公司 大输液软袋用带有穿刺功能的混药嘴的硬接口
CN2915101Y (zh) * 2006-04-14 2007-06-27 湖南千山制药机械股份有限公司 采用带保护套的混药嘴的硬接口输液袋
CN102499888A (zh) * 2011-11-11 2012-06-20 重庆莱美药业股份有限公司 一体成型的混药接口
CN202314384U (zh) * 2011-11-11 2012-07-11 重庆莱美药业股份有限公司 一体式混药接口

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2999449A1 (fr) * 2013-05-22 2016-03-30 Maco Pharma Embase d'un connecteur pour poche de perfusion

Also Published As

Publication number Publication date
CA2877510A1 (en) 2013-05-16
EP2881101A4 (en) 2016-06-22
CA2877510C (en) 2018-05-15
US20150202120A1 (en) 2015-07-23
US9775778B2 (en) 2017-10-03
EP2881101A1 (en) 2015-06-10
EP2881101B1 (en) 2017-10-18

Similar Documents

Publication Publication Date Title
WO2013067836A1 (zh) 一体式混药接口
WO2013120342A1 (zh) 双针加药器
CN206534919U (zh) 一种输液管路
WO2013013439A1 (zh) 免穿刺瓶塞及其使用方法
CN102499888B (zh) 一体成型的混药接口
US6261270B1 (en) Sleeve stopper
CN106178155B (zh) 可对多剂型进行多次直配的输液容器接口及输液容器
WO2015081557A1 (zh) 一种无针输液用组合密封盖
CN203123029U (zh) 分接口混药嘴
CN218356936U (zh) 一种翻转式肛门给药装置
CN202342463U (zh) 分体式两级卡体的混药接口
CN203123028U (zh) 组合式混药接口
CN202376460U (zh) 带卡套的接口
CN202277516U (zh) 带卡接式混药嘴的双阀盖及其输液软瓶
CN202342454U (zh) 卡接式双阀盖
CN202314384U (zh) 一体式混药接口
CN210078308U (zh) 一种输液软袋用易撕膜双接口
CN203123023U (zh) 一体式混药接口
CN206102971U (zh) 可对多剂型进行多次直配的输液容器接口及输液容器
CN215082286U (zh) 一种一次性液体配制器
CN221732006U (zh) 一种适用于外科注射用的微导管结构
CN224039623U (zh) 一种具有药液配制机构的输液装置
CN202236342U (zh) 混药嘴
CN102499889B (zh) 插接式混药嘴
CN102423283B (zh) 带混药嘴的双阀盖及其输液软瓶

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12847291

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2012847291

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2012847291

Country of ref document: EP

122 Ep: pct application non-entry in european phase

Ref document number: 12847291

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2877510

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 14415131

Country of ref document: US