WO2013134121A3 - Devices for regulation of blood pressure and heart rate - Google Patents

Devices for regulation of blood pressure and heart rate Download PDF

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Publication number
WO2013134121A3
WO2013134121A3 PCT/US2013/028865 US2013028865W WO2013134121A3 WO 2013134121 A3 WO2013134121 A3 WO 2013134121A3 US 2013028865 W US2013028865 W US 2013028865W WO 2013134121 A3 WO2013134121 A3 WO 2013134121A3
Authority
WO
WIPO (PCT)
Prior art keywords
nerve
nerves
signal
blood pressure
heart rate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/028865
Other languages
French (fr)
Other versions
WO2013134121A2 (en
Inventor
Adrianus P. Donders
Katherine S. Tweden
Mark B. Knudson
Arnold W. Thornton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vyome Holdings Inc
Original Assignee
Enteromedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enteromedics Inc filed Critical Enteromedics Inc
Priority to CN201380023543.9A priority Critical patent/CN104349815B/en
Priority to EP13710939.3A priority patent/EP2822648A2/en
Priority to JP2014560992A priority patent/JP6132856B2/en
Priority to AU2013202803A priority patent/AU2013202803C1/en
Publication of WO2013134121A2 publication Critical patent/WO2013134121A2/en
Publication of WO2013134121A3 publication Critical patent/WO2013134121A3/en
Anticipated expiration legal-status Critical
Priority to AU2016204116A priority patent/AU2016204116B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/378—Electrical supply
    • A61N1/3787—Electrical supply from an external energy source
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49002—Electrical device making

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hospice & Palliative Care (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

A method and apparatus for treating a condition associated with impaired blood pressure and/or heart rate in a subject comprising applying an electrical treatment signal, wherein the electrical treatment signal is selected to at least partially block nerve impulses, or in some embodiments, to augment nerve impulses. In embodiments, the apparatus provides a first therapy program to provide a downregulating signal to one or more nerves including renal artery, renal nerve, vagus nerve, celiac plexus, a splanchnic nerve, cardiac sympathetic nerves, spinal nerves originating between T10 to L5. In embodiments, the apparatus provides a third therapy program to provide an upregulating signal to one or more nerves including a glossopharyngeal nerve and/ or a tissue containing baroreceptors.
PCT/US2013/028865 2012-03-07 2013-03-04 Devices for regulation of blood pressure and heart rate Ceased WO2013134121A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN201380023543.9A CN104349815B (en) 2012-03-07 2013-03-04 Device for adjusting blood pressure and heart rate
EP13710939.3A EP2822648A2 (en) 2012-03-07 2013-03-04 Devices for regulation of blood pressure and heart rate
JP2014560992A JP6132856B2 (en) 2012-03-07 2013-03-04 Devices for blood pressure and heart rate regulation
AU2013202803A AU2013202803C1 (en) 2012-03-07 2013-03-04 Devices for regulation of blood pressure and heart rate
AU2016204116A AU2016204116B2 (en) 2012-03-07 2016-06-17 Devices for regulation of blood pressure and heart rate

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261607701P 2012-03-07 2012-03-07
US61/607,701 2012-03-07

Publications (2)

Publication Number Publication Date
WO2013134121A2 WO2013134121A2 (en) 2013-09-12
WO2013134121A3 true WO2013134121A3 (en) 2013-11-21

Family

ID=47902357

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/028865 Ceased WO2013134121A2 (en) 2012-03-07 2013-03-04 Devices for regulation of blood pressure and heart rate

Country Status (6)

Country Link
US (1) US20130237948A1 (en)
EP (1) EP2822648A2 (en)
JP (2) JP6132856B2 (en)
CN (1) CN104349815B (en)
AU (2) AU2013202803C1 (en)
WO (1) WO2013134121A2 (en)

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CA2823592C (en) 2011-01-03 2021-11-23 The Regents Of The University Of California High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury
AU2012304370B2 (en) 2011-09-08 2016-01-28 Nevro Corporation Selective high frequency spinal cord modulation for inhibiting pain, including cephalic and/or total body pain with reduced side effects, and associated systems and methods
JP2014533183A (en) 2011-11-11 2014-12-11 ニューロイネイブリング テクノロジーズ インコーポレイテッド Non-invasive neuromodulator to enable motor nerve, sensory, autonomy, sexual, vasomotor and cognitive recovery
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WO2013134543A1 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg Sarl Immune system neuromodulation and associated systems and methods
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AU2014228794B2 (en) 2013-03-15 2019-04-18 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
US9895539B1 (en) 2013-06-10 2018-02-20 Nevro Corp. Methods and systems for disease treatment using electrical stimulation
US10137299B2 (en) 2013-09-27 2018-11-27 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
US10149978B1 (en) 2013-11-07 2018-12-11 Nevro Corp. Spinal cord modulation for inhibiting pain via short pulse width waveforms, and associated systems and methods
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Also Published As

Publication number Publication date
EP2822648A2 (en) 2015-01-14
CN104349815B (en) 2017-07-28
US20130237948A1 (en) 2013-09-12
JP6132856B2 (en) 2017-05-24
AU2013202803B2 (en) 2016-03-17
JP2015509429A (en) 2015-03-30
AU2013202803C1 (en) 2016-06-23
AU2013202803A1 (en) 2013-09-26
JP2017104685A (en) 2017-06-15
AU2016204116A1 (en) 2016-07-21
AU2016204116B2 (en) 2017-05-11
WO2013134121A2 (en) 2013-09-12
CN104349815A (en) 2015-02-11

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