WO2013144456A1 - Pipette adjustement wheel - Google Patents

Pipette adjustement wheel Download PDF

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Publication number
WO2013144456A1
WO2013144456A1 PCT/FI2013/050358 FI2013050358W WO2013144456A1 WO 2013144456 A1 WO2013144456 A1 WO 2013144456A1 FI 2013050358 W FI2013050358 W FI 2013050358W WO 2013144456 A1 WO2013144456 A1 WO 2013144456A1
Authority
WO
WIPO (PCT)
Prior art keywords
adjustment wheel
adjustment
wheel
pipette
electrical pipette
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FI2013/050358
Other languages
French (fr)
Inventor
Ville Hintikka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Biohit Liquid Handling Oy
Original Assignee
Sartorius Biohit Liquid Handling Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius Biohit Liquid Handling Oy filed Critical Sartorius Biohit Liquid Handling Oy
Priority to JP2015502395A priority Critical patent/JP6268159B2/en
Priority to US14/385,659 priority patent/US9999881B2/en
Priority to EP13768896.6A priority patent/EP2830771B1/en
Priority to RU2014143491A priority patent/RU2630277C2/en
Priority to CN201380015199.9A priority patent/CN104185509B/en
Publication of WO2013144456A1 publication Critical patent/WO2013144456A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0237—Details of electronic control, e.g. relating to user interface
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05G—CONTROL DEVICES OR SYSTEMS INSOFAR AS CHARACTERISED BY MECHANICAL FEATURES ONLY
    • G05G5/00—Means for preventing, limiting or returning the movements of parts of a control mechanism, e.g. locking controlling member
    • G05G5/05—Means for returning or tending to return controlling members to an inoperative or neutral position, e.g. by providing return springs or resilient end-stops
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01H—ELECTRIC SWITCHES; RELAYS; SELECTORS; EMERGENCY PROTECTIVE DEVICES
    • H01H19/00—Switches operated by an operating part which is rotatable about a longitudinal axis thereof and which is acted upon directly by a solid body external to the switch, e.g. by a hand
    • H01H19/001—Thumb wheel switches
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01H—ELECTRIC SWITCHES; RELAYS; SELECTORS; EMERGENCY PROTECTIVE DEVICES
    • H01H19/00—Switches operated by an operating part which is rotatable about a longitudinal axis thereof and which is acted upon directly by a solid body external to the switch, e.g. by a hand
    • H01H19/02—Details
    • H01H19/10—Movable parts; Contacts mounted thereon
    • H01H19/14—Operating parts, e.g. turn knob
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05G—CONTROL DEVICES OR SYSTEMS INSOFAR AS CHARACTERISED BY MECHANICAL FEATURES ONLY
    • G05G1/00—Controlling members, e.g. knobs or handles; Assemblies or arrangements thereof; Indicating position of controlling members
    • G05G1/08—Controlling members for hand actuation by rotary movement, e.g. hand wheels
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01H—ELECTRIC SWITCHES; RELAYS; SELECTORS; EMERGENCY PROTECTIVE DEVICES
    • H01H19/00—Switches operated by an operating part which is rotatable about a longitudinal axis thereof and which is acted upon directly by a solid body external to the switch, e.g. by a hand
    • H01H19/36—Switches operated by an operating part which is rotatable about a longitudinal axis thereof and which is acted upon directly by a solid body external to the switch, e.g. by a hand the operating part having only two operative positions, e.g. relatively displaced by 180 degrees
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01H—ELECTRIC SWITCHES; RELAYS; SELECTORS; EMERGENCY PROTECTIVE DEVICES
    • H01H19/00—Switches operated by an operating part which is rotatable about a longitudinal axis thereof and which is acted upon directly by a solid body external to the switch, e.g. by a hand
    • H01H19/54—Switches operated by an operating part which is rotatable about a longitudinal axis thereof and which is acted upon directly by a solid body external to the switch, e.g. by a hand the operating part having at least five or an unspecified number of operative positions
    • H01H19/60—Angularly-movable actuating part carrying no contacts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00—Machine element or mechanism
    • Y10T74/20—Control lever and linkage systems
    • Y10T74/20576—Elements
    • Y10T74/20732—Handles
    • Y10T74/20834—Hand wheels

Definitions

  • an electronic pipette which comprises an adjustment wheel that also functions as push key. With the adjustment wheel one can select the volume, control calibration and proceed in the menu.
  • a pipette is described that has an adjustment wheel that allows, by rotating it, the selection of mode of use, for example manual pipetting, pipetting and mixing, titration and so on. This function is not connected to a push key but resides in a separate adjustment wheel.
  • EP 1 632 840 Al describes a pipette having a display on its hook in front of which there is an adjustment wheel. With the adjustment wheel functions can be selected, such as the volume of the liquid to be pipetted, proceeding in the menu, calibration of the pipette, etc.
  • the system according to the invention solves the above mentioned problems with a new solution that comprises members for returning the adjustment wheel to its initial position when released.
  • This can be achieved with a spring return adjustment wheel solution.
  • the spring return is implemented in two stages. When the adjustment wheel is first rotated, there is initially a brief, rather light adjustment wheel movement. After this brief and light adjustment wheel movement, the spring force at first increases stepwise after which it increases towards the extreme of the movement.
  • the advantage is achieved that the stepwise or very slowly progressing adjustment and on the other hand the fast, and especially the adjustment occurring at an accelerating speed can be separated within the same member as two distinctly separate events.
  • the angle of rotation of the adjustment wheel can be detected for example by a magnetic sensor or an optic reader head arrangement.
  • an adjustment wheel When an adjustment wheel is used for programming a pipette, the adjustment is simultaneously both sensitive and very fast and interactive. The interactivity is emphasized when combined with visual feedback, for example in the form of a bar increasing with the adjustment or a sound effect.
  • Another significant advantage of the invention in addition to the fast, controlled adjustment is the possibility to use the adjustment wheel for directly driving the pipette in so called manual/measurement mode. This means that the operating machinery, i.e. the piston is driven freely up-and-down by the adjustment wheel.
  • the two-step ad- justment also enables the best possible touch e.g.
  • the adjustment wheel is preferably situated in the upper part of the pipette, most preferably at the top of the pipette where it is ergonomic and easy to use with one hand. That is, the adjustment wheel can be moved by a single movement of the thumb of the hand holding the pipette. This also means that all adjustments and choices made in the menu can be made easily without releasing the grip on the pipette or changing the grip and at the same time the display easily remains visible at all times.
  • the movement of the piston is also controlled by the adjustment wheel. This means, therefore, that there is no need to change the grip between adjustment and pipetting.
  • the operating key which is used for dispensing the liquid and which controls the movement of the piston is separate, and the adjustment wheel is set around it, functioning independently from the operating key.
  • figures 1-3 a technical solution for achieving the function of the present invention is shown.
  • Figure 1 illustrates parts of the adjustment wheel including the adjustment wheel 1, the primary spring 3 and the secondary spring 4 and their attachment point to the body 2 of the pipette.
  • the adjustment wheel 1 is installed in the body 2 of the pipette such, that it can be turned in both directions in respect of the axis.
  • the primary spring is installed thus, that the outward bent arms of the spring are pressed to both sides of a first shoulder 5 in the body and at the same time center the adjustment wheel to its center position.
  • the secondary spring is installed such, that the se- cond guide 6 of the adjustment wheel is situated symmetrically in respect to a second shoulder 7 of the body.
  • the first guide 8 engages the primary spring claw 3a that resists the rotational movement lightly until the second shoulder of the body hits the spring claw 4a of the secondary spring. Then the greater force of the biased secondary spring is initially felt as a distinct stop, and as the wheel is turned further a growing force is directed to the wheel until the movement is halted in its end position against the stop pins 9 of the body. When the wheel is released, the springs return the wheel to its original central position.
  • the figures also show the detection of the angle of rotation implemented by magnets 10 and a magnetic sensor 11.
  • the sensitivity of the adjustment wheel and the threshold between the two different adjustment areas can be adjusted by selecting the spring constants of the spring material to be suitable for the purpose.
  • a spring-loaded cam mechanism can be used.
  • the turning part has two cams, the first one immediately engaging the spring-loaded member and the second one slightly later engaging the stiffer spring- loaded member.
  • the spring-loaded member may for example be spring steel wire, which is bent by the cam as the adjustment wheel is turned.
  • a spring-loaded roller is fastened at the turning part, and on the opposite side is a shape which provides, an accurate two- phase centering torque profile.
  • the spring-loaded roller can also be on the side of the body and the shape that the spring-loaded roller follows can be on the adjustment wheel side.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Human Computer Interaction (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Description

PIPETTE ADJUSTMENT WHEEL
Background
Electronic pipettes are traditionally adjusted and controlled by pressing keys. For ex- ample volume adjustment is often implemented in this way. A standard implementation is arrow keys with which the volume can be adjusted to be increased or decreased. Almost without exception, the same arrow keys are also used for other functions, for example for advancing in a menu. Conventionally a single touch of an arrow key causes a change of one adjustment step, and pressing the key for a longer period will result in an accelerated change of the reading. However, an adjustment canied out in this way has its drawbacks. The adjustment is not very fast at least in case the adjustment target value is far from the initial reading. Moreover the keys are often in connection with the display and can thus be economically poorly located. There are designs where functions are adjusted using adjustment wheels, but they have not as yet brought any improvement to the speed or ease of the adjustment.
In document WO 2010/034290 A2, an electronic pipette is described, which comprises an adjustment wheel that also functions as push key. With the adjustment wheel one can select the volume, control calibration and proceed in the menu.
In document EP 1 878 500 Al, a pipette is described that has an adjustment wheel that allows, by rotating it, the selection of mode of use, for example manual pipetting, pipetting and mixing, titration and so on. This function is not connected to a push key but resides in a separate adjustment wheel.
EP 1 632 840 Al describes a pipette having a display on its hook in front of which there is an adjustment wheel. With the adjustment wheel functions can be selected, such as the volume of the liquid to be pipetted, proceeding in the menu, calibration of the pipette, etc.
The solutions mentioned above are such in which the adjustment wheel is of the incrementally rotating type. There are also solutions having a touch screen with a touch wheel. In existing, such as those mentioned above, adjustment wheel solutions of this type the adjustment wheel is of the same type as the adjustment wheel of a car radio. This solution does not offer good control sensitivity especially when the reading needs to be changed much at once and to an accurate specific value. To speed up the adjustment in this case the wheel needs to be rotated fast in pulses for a fast change of the reading. This will easily lead to exceeding or falling short of the wanted reading, and setting the accurate reading will cause additional iteration.
Description of the invention The system according to the invention solves the above mentioned problems with a new solution that comprises members for returning the adjustment wheel to its initial position when released. This can be achieved with a spring return adjustment wheel solution. The spring return is implemented in two stages. When the adjustment wheel is first rotated, there is initially a brief, rather light adjustment wheel movement. After this brief and light adjustment wheel movement, the spring force at first increases stepwise after which it increases towards the extreme of the movement.
With this solution the advantage is achieved that the stepwise or very slowly progressing adjustment and on the other hand the fast, and especially the adjustment occurring at an accelerating speed can be separated within the same member as two distinctly separate events. The angle of rotation of the adjustment wheel can be detected for example by a magnetic sensor or an optic reader head arrangement.
When the rotation angle of the adjustment wheel has been brought into electronic form, different speed response profiles can be developed in the control program of the pipette for optimal implementation of the turning of the adjustment wheel and the function which is to be adjusted.
When an adjustment wheel is used for programming a pipette, the adjustment is simultaneously both sensitive and very fast and interactive. The interactivity is emphasized when combined with visual feedback, for example in the form of a bar increasing with the adjustment or a sound effect. Another significant advantage of the invention in addition to the fast, controlled adjustment is the possibility to use the adjustment wheel for directly driving the pipette in so called manual/measurement mode. This means that the operating machinery, i.e. the piston is driven freely up-and-down by the adjustment wheel. The two-step ad- justment also enables the best possible touch e.g. in the so-called titration mode, in which the pipette must be able to move in a controlled manner at various speeds, but during the same run also by the smallest possible adjustment step in a stepwise manner. The adjustment wheel is preferably situated in the upper part of the pipette, most preferably at the top of the pipette where it is ergonomic and easy to use with one hand. That is, the adjustment wheel can be moved by a single movement of the thumb of the hand holding the pipette. This also means that all adjustments and choices made in the menu can be made easily without releasing the grip on the pipette or changing the grip and at the same time the display easily remains visible at all times.
In a preferred embodiment of the invention the movement of the piston is also controlled by the adjustment wheel. This means, therefore, that there is no need to change the grip between adjustment and pipetting.
In another preferred embodiment the operating key which is used for dispensing the liquid and which controls the movement of the piston is separate, and the adjustment wheel is set around it, functioning independently from the operating key. In figures 1-3, a technical solution for achieving the function of the present invention is shown.
Figure 1 illustrates parts of the adjustment wheel including the adjustment wheel 1, the primary spring 3 and the secondary spring 4 and their attachment point to the body 2 of the pipette.
In figure 2 the adjustment wheel 1 is installed in the body 2 of the pipette such, that it can be turned in both directions in respect of the axis. There are two torsion springs inside the wheel; the primary spring 3 and the secondary spring 4. The primary spring is installed thus, that the outward bent arms of the spring are pressed to both sides of a first shoulder 5 in the body and at the same time center the adjustment wheel to its center position. Correspondingly, the secondary spring is installed such, that the se- cond guide 6 of the adjustment wheel is situated symmetrically in respect to a second shoulder 7 of the body.
When the adjustment wheel is turned clockwise as shown in figure 3, the first guide 8 engages the primary spring claw 3a that resists the rotational movement lightly until the second shoulder of the body hits the spring claw 4a of the secondary spring. Then the greater force of the biased secondary spring is initially felt as a distinct stop, and as the wheel is turned further a growing force is directed to the wheel until the movement is halted in its end position against the stop pins 9 of the body. When the wheel is released, the springs return the wheel to its original central position.
The figures also show the detection of the angle of rotation implemented by magnets 10 and a magnetic sensor 11.
The sensitivity of the adjustment wheel and the threshold between the two different adjustment areas can be adjusted by selecting the spring constants of the spring material to be suitable for the purpose.
Instead of using torsion springs, a spring-loaded cam mechanism can be used. In this implementation the turning part has two cams, the first one immediately engaging the spring-loaded member and the second one slightly later engaging the stiffer spring- loaded member. The spring-loaded member may for example be spring steel wire, which is bent by the cam as the adjustment wheel is turned.
According to another embodiment of the invention, a spring-loaded roller is fastened at the turning part, and on the opposite side is a shape which provides, an accurate two- phase centering torque profile. The spring-loaded roller can also be on the side of the body and the shape that the spring-loaded roller follows can be on the adjustment wheel side.

Claims

Claims
1. Adjustment wheel for an electrical pipette, characterized in that the adjustment wheel solution comprises members for returning the adjustment wheel to its original position when the wheel is released.
2. The adjustment wheel of claim 1, characterized in, that the adjustment wheel solution is spring returned.
3. The adjustment wheel for an electrical pipette of claim 1 or 2, wherein the force increases with the angle at which the adjustment wheel is turned.
4. The adjustment wheel for an electrical pipette of claim 1 or 2, characterized in that it comprises two adjustment areas.
5. The adjustment wheel for an electrical pipette of claim 4, characterized in that within the first adjustment area the rotation angle of the wheel is short and the required force is essentially smaller than within the second adjustment area which is longer and the force increases in relation to the rotation angle.
6. The adjustment wheel for an electrical pipette of any of claims 1 to 5, which adjustment wheel has a linear response.
7. The adjustment wheel for an electrical pipette of any of claims 1 to 5, which adjustment wheel has a non-linear response.
8. The adjustment wheel for a an electrical pipette of any of claims I to 7, wherein the adjustment wheel also controls the movement of the piston.
9. The adjustment wheel for an electrical pipette of any of claims 1 to 7. wherein the adjustment wheel functions independently from the operating key controlling the movement of the piston.
10. The adjustment wheel for an electrical pipette of claim 5, characterized in that the different responses of the adjustment areas are produced using two torsion springs in the structure.
11. The adjustment wheel for an electrical pipette of claim 10, characterized in that the threshold between the two adjustment areas can be adjusted by selecting the materials of the springs.
12. The adjustment wheel for an electrical pipette of any of claims 1 to 1 1, characterized in that the rotational angle of the adjustment wheel is detected using a magnetic sensor.
13. The adjustment wheel for an electrical pipette of any of claims 1 to 11, characterized in, that the rotational angle of the adjustment wheel is detected using an optical reader head arrangement.
PCT/FI2013/050358 2012-03-30 2013-04-02 Pipette adjustement wheel Ceased WO2013144456A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2015502395A JP6268159B2 (en) 2012-03-30 2013-04-02 Pipette adjustment wheel
US14/385,659 US9999881B2 (en) 2012-03-30 2013-04-02 Pipette adjustment wheel
EP13768896.6A EP2830771B1 (en) 2012-03-30 2013-04-02 Pipette with adjustement wheel
RU2014143491A RU2630277C2 (en) 2012-03-30 2013-04-02 Adjustment wheel of the pipette
CN201380015199.9A CN104185509B (en) 2012-03-30 2013-04-02 Pipet regulation wheel

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20125369 2012-03-30
FI20125369A FI125309B (en) 2012-03-30 2012-03-30 Steering wheel for pipette

Publications (1)

Publication Number Publication Date
WO2013144456A1 true WO2013144456A1 (en) 2013-10-03

Family

ID=49258315

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2013/050358 Ceased WO2013144456A1 (en) 2012-03-30 2013-04-02 Pipette adjustement wheel

Country Status (7)

Country Link
US (1) US9999881B2 (en)
EP (1) EP2830771B1 (en)
JP (1) JP6268159B2 (en)
CN (1) CN104185509B (en)
FI (1) FI125309B (en)
RU (1) RU2630277C2 (en)
WO (1) WO2013144456A1 (en)

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WO2019209213A3 (en) * 2017-12-27 2020-04-30 Eczacibasi Yapi Gerecleri Sanayi Ve Ticaret Anonim Sirketi An adjusting knob

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US10466736B2 (en) * 2017-01-24 2019-11-05 Electrolux Home Products, Inc. Self-centering spring return mechanism for an appliance knob
CN111408419A (en) * 2019-01-07 2020-07-14 苏州赛尼特格尔实验室科技有限公司 Combined regulator of electronic pipettor
CN111644217A (en) * 2020-06-18 2020-09-11 苏州赛尼特格尔实验室科技有限公司 Adjusting operation method of liquid transfer device
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US10606302B2 (en) 2017-03-13 2020-03-31 Electrolux Home Products, Inc. Self-centering mechanism for an appliance knob
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RU2630277C2 (en) 2017-09-06
FI125309B (en) 2015-08-31
CN104185509B (en) 2016-10-12
JP2015516290A (en) 2015-06-11
US20150047457A1 (en) 2015-02-19
CN104185509A (en) 2014-12-03
RU2014143491A (en) 2016-05-27
US9999881B2 (en) 2018-06-19
JP6268159B2 (en) 2018-01-24
EP2830771A1 (en) 2015-02-04
EP2830771A4 (en) 2016-01-13
FI20125369L (en) 2013-10-01
EP2830771B1 (en) 2020-05-27

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