WO2013176948A3 - Method of operation of a syngas fermentation process - Google Patents

Method of operation of a syngas fermentation process Download PDF

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Publication number
WO2013176948A3
WO2013176948A3 PCT/US2013/041250 US2013041250W WO2013176948A3 WO 2013176948 A3 WO2013176948 A3 WO 2013176948A3 US 2013041250 W US2013041250 W US 2013041250W WO 2013176948 A3 WO2013176948 A3 WO 2013176948A3
Authority
WO
WIPO (PCT)
Prior art keywords
syngas
providing
fermentation
fermentation process
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/041250
Other languages
French (fr)
Other versions
WO2013176948A2 (en
Inventor
Syrona Scott
Song Liu
Ching-Whan Ko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jupeng Bio SA
Original Assignee
Ineos Bio SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2013266676A priority Critical patent/AU2013266676B2/en
Priority to JP2015514061A priority patent/JP6228596B2/en
Priority to BR122021020217-6A priority patent/BR122021020217B1/en
Priority to RU2014151620A priority patent/RU2623170C2/en
Priority to CN201380026747.8A priority patent/CN104822836B/en
Priority to KR1020147035891A priority patent/KR102046677B1/en
Priority to EP13728863.5A priority patent/EP2852675B1/en
Priority to CA2874086A priority patent/CA2874086C/en
Priority to KR1020197033343A priority patent/KR102142234B1/en
Application filed by Ineos Bio SA filed Critical Ineos Bio SA
Priority to CN201810500522.6A priority patent/CN108841874B/en
Priority to BR112014028956-5A priority patent/BR112014028956B1/en
Publication of WO2013176948A2 publication Critical patent/WO2013176948A2/en
Publication of WO2013176948A3 publication Critical patent/WO2013176948A3/en
Anticipated expiration legal-status Critical
Priority to ZA2014/09445A priority patent/ZA201409445B/en
Priority to AU2016203101A priority patent/AU2016203101B2/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/065Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/08Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/74Undefined extracts from fungi, e.g. yeasts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A process is provided for fermentation of syngas that is effective for reducing conductivity and providing an alcohol STY of about 10 g ethanol/(L•day). The process includes introducing the syngas into a reactor vessel and providing a nitrogen feed rate to the reactor vessel of about 100 mg or more nitrogen/gram of cells produced. Fermentation of the syngas is effective for providing a fermentation medium having an average conductivity of about 16 mS/cm or less and an STY of 10 g ethanol/(L•day) or more.
PCT/US2013/041250 2012-05-22 2013-05-15 Method of operation of a syngas fermentation process Ceased WO2013176948A2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
KR1020197033343A KR102142234B1 (en) 2012-05-22 2013-05-15 Method of operation of a syngas fermentation process
BR122021020217-6A BR122021020217B1 (en) 2012-05-22 2013-05-15 fermentation medium
RU2014151620A RU2623170C2 (en) 2012-05-22 2013-05-15 Way to manage the process of synthesis-gas fermentations
CN201380026747.8A CN104822836B (en) 2012-05-22 2013-05-15 Method of Operation of Syngas Fermentation Process
KR1020147035891A KR102046677B1 (en) 2012-05-22 2013-05-15 Method of operation of a syngas fermentation process
EP13728863.5A EP2852675B1 (en) 2012-05-22 2013-05-15 Method of operation of a syngas fermentation process
CA2874086A CA2874086C (en) 2012-05-22 2013-05-15 Method of operation of a syngas fermentation process
AU2013266676A AU2013266676B2 (en) 2012-05-22 2013-05-15 Method of operation of a syngas fermentation process
CN201810500522.6A CN108841874B (en) 2012-05-22 2013-05-15 Method for operating a synthesis gas fermentation process
JP2015514061A JP6228596B2 (en) 2012-05-22 2013-05-15 How to operate the syngas fermentation process
BR112014028956-5A BR112014028956B1 (en) 2012-05-22 2013-05-15 Process for fermenting synthesis gas
ZA2014/09445A ZA201409445B (en) 2012-05-22 2014-12-19 Method of operation of a syngas fermentation process
AU2016203101A AU2016203101B2 (en) 2012-05-22 2016-05-12 Method of operation of a syngas fermentation process

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201261650093P 2012-05-22 2012-05-22
US201261650098P 2012-05-22 2012-05-22
US61/650,098 2012-05-22
US61/650,093 2012-05-22
US201261726225P 2012-11-14 2012-11-14
US61/726,225 2012-11-14
US13/890,777 US10100338B2 (en) 2012-05-22 2013-05-09 Method of operation of a syngas fermentation process
US13/890,777 2013-05-09

Publications (2)

Publication Number Publication Date
WO2013176948A2 WO2013176948A2 (en) 2013-11-28
WO2013176948A3 true WO2013176948A3 (en) 2014-05-01

Family

ID=49621897

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/041250 Ceased WO2013176948A2 (en) 2012-05-22 2013-05-15 Method of operation of a syngas fermentation process

Country Status (13)

Country Link
US (2) US10100338B2 (en)
EP (1) EP2852675B1 (en)
JP (1) JP6228596B2 (en)
KR (2) KR102046677B1 (en)
CN (2) CN108841874B (en)
AR (1) AR091109A1 (en)
AU (2) AU2013266676B2 (en)
BR (2) BR122021020217B1 (en)
CA (1) CA2874086C (en)
RU (1) RU2623170C2 (en)
TW (1) TWI650422B (en)
WO (1) WO2013176948A2 (en)
ZA (1) ZA201409445B (en)

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US9885063B2 (en) * 2013-06-10 2018-02-06 Ineos Bio Sa Process for fermenting co-containing gaseous substrates in a low phosphate medium effective for reducing water usage
US9850503B2 (en) * 2013-06-10 2017-12-26 Ineos Bio Sa Control of conductivity in anaerobic fermentation
US9617566B2 (en) 2014-07-11 2017-04-11 Lanzatech New Zealand Limited Control of bioreactor processes
US9765408B2 (en) * 2014-08-12 2017-09-19 Ineos Bio Sa Process for controlling fermentation of co-containing substrates
EP3050967A1 (en) * 2015-01-28 2016-08-03 Evonik Degussa GmbH A method of producing higher alcohols
CN107779477B (en) * 2016-08-25 2021-10-12 中国科学院天津工业生物技术研究所 Culture system and culture method for producing alcohol by fermenting synthesis gas by using gas-feeding anaerobic bacteria
CN106399387A (en) * 2016-09-20 2017-02-15 江南大学 Nitrogen defect control method for production of ethanol through fermentation of synthesis gas with mixed bacteria
US11333607B2 (en) 2018-10-02 2022-05-17 Electronics And Telecommunications Research Institute Fluorescent signal detection apparatus using diagnostic kit
KR102722662B1 (en) 2021-09-17 2024-10-29 한국과학기술연구원 Medium composition for producing alcohol from synthetic gas comprising ethanol and method for producing alcohol using the same

Citations (3)

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WO2007117157A1 (en) * 2006-04-07 2007-10-18 Lanzatech New Zealand Limited Microbial fermentation of gaseous substrates to produce alcohols
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Also Published As

Publication number Publication date
AU2016203101B2 (en) 2018-04-19
AU2016203101A1 (en) 2016-06-02
KR20150089928A (en) 2015-08-05
ZA201409445B (en) 2017-08-30
CA2874086C (en) 2021-05-18
AR091109A1 (en) 2015-01-14
CN108841874B (en) 2022-03-29
TWI650422B (en) 2019-02-11
CA2874086A1 (en) 2013-11-28
TW201400615A (en) 2014-01-01
US10858672B2 (en) 2020-12-08
KR102046677B1 (en) 2019-11-19
BR122021020217B1 (en) 2022-04-26
JP2015520612A (en) 2015-07-23
AU2013266676A1 (en) 2015-01-22
BR112014028956B1 (en) 2022-01-25
CN104822836B (en) 2018-05-25
WO2013176948A2 (en) 2013-11-28
KR102142234B1 (en) 2020-08-07
CN104822836A (en) 2015-08-05
US10100338B2 (en) 2018-10-16
EP2852675A2 (en) 2015-04-01
KR20190129140A (en) 2019-11-19
CN108841874A (en) 2018-11-20
EP2852675B1 (en) 2020-09-30
BR112014028956A2 (en) 2017-07-18
JP6228596B2 (en) 2017-11-08
US20190040418A1 (en) 2019-02-07
RU2014151620A (en) 2016-07-10
US20130316422A1 (en) 2013-11-28
AU2013266676B2 (en) 2016-05-05
RU2623170C2 (en) 2017-06-22

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