WO2014028534A3 - Leukemia classification using cpd data - Google Patents

Leukemia classification using cpd data Download PDF

Info

Publication number
WO2014028534A3
WO2014028534A3 PCT/US2013/054792 US2013054792W WO2014028534A3 WO 2014028534 A3 WO2014028534 A3 WO 2014028534A3 US 2013054792 W US2013054792 W US 2013054792W WO 2014028534 A3 WO2014028534 A3 WO 2014028534A3
Authority
WO
WIPO (PCT)
Prior art keywords
individual
biological sample
type
sub
cpd data
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/054792
Other languages
French (fr)
Other versions
WO2014028534A2 (en
Inventor
Kyungja HAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Priority to KR1020157006172A priority Critical patent/KR20150041130A/en
Priority to BR112015003000A priority patent/BR112015003000A2/en
Priority to CN201380047644.XA priority patent/CN104704344A/en
Priority to EP13753238.8A priority patent/EP2883036A2/en
Priority to JP2015526763A priority patent/JP2015524571A/en
Publication of WO2014028534A2 publication Critical patent/WO2014028534A2/en
Publication of WO2014028534A3 publication Critical patent/WO2014028534A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N15/1436—Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Hematology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Embodiments of the present invention encompass automated systems and methods for predicting an acute leukemia sub-type of an individual diagnosed with acute leukemia based on a biological sample obtained from blood of the individual. Exemplary techniques involve correlating aspects of direct current (DC) impedance, radiofrequency (RF) conductivity, and/or light measurement data obtained from the biological sample with an acute leukemic sub-type of the individual.
PCT/US2013/054792 2012-08-13 2013-08-13 Leukemia classification using cpd data Ceased WO2014028534A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
KR1020157006172A KR20150041130A (en) 2012-08-13 2013-08-13 Leukemia classification using cpd data
BR112015003000A BR112015003000A2 (en) 2012-08-13 2013-08-13 leukemia classification using cpd data
CN201380047644.XA CN104704344A (en) 2012-08-13 2013-08-13 Leukemia classification using CPD data
EP13753238.8A EP2883036A2 (en) 2012-08-13 2013-08-13 Leukemia classification using cpd data
JP2015526763A JP2015524571A (en) 2012-08-13 2013-08-13 Leukemia classification using CPD data

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261682545P 2012-08-13 2012-08-13
US61/682,545 2012-08-13
US13/965,838 2013-08-13
US13/965,838 US20140172321A1 (en) 2012-08-13 2013-08-13 Leukemia classification using cpd data

Publications (2)

Publication Number Publication Date
WO2014028534A2 WO2014028534A2 (en) 2014-02-20
WO2014028534A3 true WO2014028534A3 (en) 2014-06-19

Family

ID=49035942

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/054792 Ceased WO2014028534A2 (en) 2012-08-13 2013-08-13 Leukemia classification using cpd data

Country Status (6)

Country Link
US (1) US20140172321A1 (en)
JP (1) JP2015524571A (en)
KR (1) KR20150041130A (en)
CN (1) CN104704344A (en)
BR (1) BR112015003000A2 (en)
WO (1) WO2014028534A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9310328B1 (en) * 2015-06-17 2016-04-12 King Abdulaziz University Method of detecting leukemia
EP3408773B1 (en) * 2016-01-28 2023-09-20 Beckman Coulter, Inc. Infection detection and differentiation systems and methods
KR20190120318A (en) 2017-02-28 2019-10-23 베크만 컬터, 인코포레이티드 Interoperable Disease Management System
US11852640B2 (en) 2017-10-27 2023-12-26 Beckman Coulter, Inc. Hematology analyzers and methods of operation
KR102084786B1 (en) 2018-04-05 2020-03-04 광운대학교 산학협력단 Microwave treatment apparatus for blood cancer therapy
KR20190117377A (en) 2018-04-06 2019-10-16 광운대학교 산학협력단 Microwave treatment apparatus and method for blood cancer therapy
CN112041938A (en) * 2018-04-20 2020-12-04 拜克门寇尔特公司 Sepsis infection determination system and method
US11538566B2 (en) 2018-05-23 2022-12-27 Beckman Coulter, Inc. Sample analysis with test determination based on identified condition
US11521706B2 (en) 2018-04-20 2022-12-06 Beckman Coulter, Inc. Testing and representing suspicion of sepsis
WO2019240876A1 (en) 2018-06-15 2019-12-19 Beckman Coulter, Inc. Method of determining sepsis in the presence of blast flagging
JP7333637B2 (en) * 2018-09-28 2023-08-25 国立大学法人 東京大学 Particle detector
CN114127861A (en) 2019-07-12 2022-03-01 贝克曼库尔特有限公司 Methods for detecting sepsis using vital signs including systolic blood pressure, hematologic parameters, and combinations thereof
EP3997461B1 (en) 2019-07-12 2026-02-25 Beckman Coulter, Inc. Systems and methods for evaluating immune response to infection

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988007198A1 (en) * 1987-03-13 1988-09-22 Coulter Electronics, Inc. Multi-part differential analyzing apparatus utilizing light scatter techniques
WO1999005523A1 (en) * 1997-07-25 1999-02-04 Coulter International Corp. Method for determination of leukocytes and hemoglobin concentration in blood
WO2000049385A2 (en) * 1999-02-16 2000-08-24 Coulter International Corp. Method and apparatus for analyzing cells in a whole blood sample
US20030219850A1 (en) * 2002-05-16 2003-11-27 Sysmex Corporation Method for automatically analyzing nucleated bone marrow cells
US20060269970A1 (en) * 2004-05-21 2006-11-30 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0610774B1 (en) * 1993-02-09 2001-03-28 Becton, Dickinson and Company Automatic lineage assignment of acute leukemias by flow cytometry
KR100738401B1 (en) * 2005-05-11 2007-07-11 다이노나(주) Antigen Determination Sites of Acute Leukemia- and Lymphoblastic Lymphoma-specific CD43 and Uses thereof
US9464978B2 (en) * 2009-03-04 2016-10-11 Beckman Coulter, Inc. Cross-instrument method and system for cell population discrimination
AU2011276590A1 (en) * 2010-06-28 2013-01-31 Threshold Pharmaceuticals, Inc. Treatment of blood cancer
WO2012061510A2 (en) * 2010-11-03 2012-05-10 Merck Sharp & Dohme Corp. Methods of predicting cancer cell response to therapeutic agents

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988007198A1 (en) * 1987-03-13 1988-09-22 Coulter Electronics, Inc. Multi-part differential analyzing apparatus utilizing light scatter techniques
WO1999005523A1 (en) * 1997-07-25 1999-02-04 Coulter International Corp. Method for determination of leukocytes and hemoglobin concentration in blood
WO2000049385A2 (en) * 1999-02-16 2000-08-24 Coulter International Corp. Method and apparatus for analyzing cells in a whole blood sample
US20030219850A1 (en) * 2002-05-16 2003-11-27 Sysmex Corporation Method for automatically analyzing nucleated bone marrow cells
US20060269970A1 (en) * 2004-05-21 2006-11-30 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
A BRUNO ET AL: "Diagnosis of acute myeloid leukemia and system Coulter VCS", HAEMATOLOGICA, 1 September 1994 (1994-09-01) - 4 December 2013 (2013-12-04), ITALY, pages 420 - 428, XP055091707, Retrieved from the Internet <URL:http://www.ncbi.nlm.nih.gov/pubmed/7843628> [retrieved on 20131204] *
ANONYMUS: "Advancements in Technology: WBC Differential Methodology", 1 January 2009 (2009-01-01), pages 1 - 2, XP055091644, Retrieved from the Internet <URL:http://www.beckmancoulter.de/beckman2_media/Klinische Diagnostik/Instrumente/HämatologieBlutgruppenserologie/UniCelDxH/Boschüren DxH/UniCel DxH 800 WBC Differential Methodology.pdf> [retrieved on 20131204] *
ANONYMUS: "UniCel DxH 800 Coulter Cellular Analysis System", 1 January 2008 (2008-01-01), pages 1 - 14, XP055092032, Retrieved from the Internet <URL:ftp://wsip-174-79-44-171.ph.ph.cox.net/^InactiveProjects/0805 UC Irvine - Lab/Communications/Vendors/Beckman Coulter/DxH_Technology_Parameter Specs_rev3.pdf> [retrieved on 20131206] *
SEUNGWON JUNG ET AL: "Differential Blast Counts Obtained by Automated Blood Cell Analyzers", THE KOREAN JOURNAL OF LABORATORY MEDICINE, vol. 30, no. 6, 1 January 2010 (2010-01-01), pages 540 - 545, XP055091708, ISSN: 1598-6535, DOI: 10.3343/kjlm.2010.30.6.540 *

Also Published As

Publication number Publication date
US20140172321A1 (en) 2014-06-19
BR112015003000A2 (en) 2017-07-04
CN104704344A (en) 2015-06-10
KR20150041130A (en) 2015-04-15
JP2015524571A (en) 2015-08-24
WO2014028534A2 (en) 2014-02-20

Similar Documents

Publication Publication Date Title
IN2014DN10974A (en)
IN2015DN02927A (en)
BR112015011723A2 (en) screening for tuberculosis using cpd data
BR112014031365A2 (en) methods of detecting disease or conditions
SG11202109764VA (en) Methods, devices, and systems for analyte detection and analysis
WO2016086033A3 (en) Analyte monitoring systems and related test and monitoring methods
WO2012122536A3 (en) Systems and methods for high-throughput detection of an analyte in a sample
HK1255230A1 (en) System and method for management, execution, and analysis of laboratory experiments
EP4435407A3 (en) Blood analysis method, control device, and blood cell analyzer
EP3625563A4 (en) Diagnostic assays for detecting, quantifying, and/or tracking microbes and other analytes
HK1254531A1 (en) Methods for preparing and analyzing tumor tissue samples for detection and monitoring of cancers
MX384536B (en) SYSTEMS AND METHODS FOR MULTIPLE ANALYSES.
EP3572529A3 (en) Gene methylation based colorectal cancer diagnosis
WO2012151585A3 (en) Method and system for analyzing a task trajectory
HK1222780A1 (en) Ophthalmic lens with a microfluidic system
IL234992A (en) Methods and systems for detecting an analyte or classifying a sample
EP2610621A3 (en) Blood cell analyzer, blood cell analyzing method, and non-transitory storage medium
NZ629555A (en) Monocyte biomarkers for cancer detection
HK1220253A1 (en) Methods of detecting prostate cancer
MX2015012303A (en) A noninvasive method for measuring oxidative stress and oxidative damage from skin.
EP3256849A4 (en) Devices, solutions and methods for sample collection related applications, analysis and diagnosis
EP4450648A3 (en) Determining a physiological condition in an individual by analyzing cell-free dna fragment endpoints in a biological sample
WO2018067571A3 (en) Computer implemented discovery of biomarkers for blood brain barrier disruption
WO2012083274A3 (en) Methods for diagnosis, prognosis and methods of treatment
IL250867B (en) Preparations, methods and kits for diagnosing gastroenteropancreatic neuroendocrine tumor

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13753238

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 2015526763

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2013753238

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 20157006172

Country of ref document: KR

Kind code of ref document: A

REG Reference to national code

Ref country code: BR

Ref legal event code: B01A

Ref document number: 112015003000

Country of ref document: BR

ENP Entry into the national phase

Ref document number: 112015003000

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20150211