WO2014199106A3 - Utilisation de la dermicidine pour le traitement de la peau a tendance acneique, grasse ou pour la prevention d'apparition d'imperfections - Google Patents

Utilisation de la dermicidine pour le traitement de la peau a tendance acneique, grasse ou pour la prevention d'apparition d'imperfections Download PDF

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Publication number
WO2014199106A3
WO2014199106A3 PCT/FR2014/051479 FR2014051479W WO2014199106A3 WO 2014199106 A3 WO2014199106 A3 WO 2014199106A3 FR 2014051479 W FR2014051479 W FR 2014051479W WO 2014199106 A3 WO2014199106 A3 WO 2014199106A3
Authority
WO
WIPO (PCT)
Prior art keywords
skin
acne
oily
imperfections
appearance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2014/051479
Other languages
English (en)
Other versions
WO2014199106A2 (fr
Inventor
Audrey Gueniche
Dominique Bernard
Mark Donovan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR1355577A external-priority patent/FR3006890B1/fr
Priority claimed from FR1355579A external-priority patent/FR3006897A1/fr
Application filed by LOreal SA filed Critical LOreal SA
Priority to EP14752353.4A priority Critical patent/EP3007718A2/fr
Priority to US14/897,328 priority patent/US20160361384A1/en
Publication of WO2014199106A2 publication Critical patent/WO2014199106A2/fr
Publication of WO2014199106A3 publication Critical patent/WO2014199106A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9446Antibacterials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/20Dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention a, notamment, pour objet l'utilisation d'une composition cosmétique et/ou thérapeutique, notamment dermatologique contenant au moins une séquence d'acides aminés de la Dermicidine, d'un analogue ou d'un fragment de celle-ci, ou d'au moins une séquence d'acides nucléiques codant cette séquence, pour prévenir l'apparition d'imperfections, ainsi que pour le traitement et/ou la prévention et/ou le diagnostic de la peau acnéique et/ou grasse ou à tendance acnéique et/ou grasse. Elle concerne également un procédé d'application de la composition cosmétique précitée pour la prévention d'apparition d'imperfections et le traitement de la peau à tendance acnéique et/ou grasse. Elle concerne, en outre, un procédé de traitement d'une peau acnéique comprenant l'application topique sur ladite peau de la composition pharmaceutique pour le traitement de la peau acnéique et/ou grasse. La présente invention a, également, pour objet l'utilisation d'un biomarqueur pour le diagnostic des peaux acnéique et/ou grasse ou à tendance acnéiques et/ou grasse.
PCT/FR2014/051479 2013-06-14 2014-06-16 Utilisation cosmétique de la dermicidine, analogues ou fragments de celle-ci pour la prévention et/ou le traitement et le diagnostic de la peau grasse et des désordres esthétiques cutanés qui y sont associés Ceased WO2014199106A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP14752353.4A EP3007718A2 (fr) 2013-06-14 2014-06-16 Utilisation de la dermicidine pour le traitement de la peau a tendance acneique, grasse ou pour la prevention d'apparition d'imperfections
US14/897,328 US20160361384A1 (en) 2013-06-14 2014-06-16 Cosmetic use of dermicidin, or analogues or fragments thereof, for the prevention and/or treatment and diagnosis of oily skin and aesthetic skin disorders associated therewith

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR1355577 2013-06-14
FR1355577A FR3006890B1 (fr) 2013-06-14 2013-06-14 Utilisation cosmetique de la dermicidine, analogues ou fragments de celle-ci pour la prevention et/ou le traitement et le diagnostic de la peau grasse et des desordres esthetiques cutanes qui y sont associes
FR1355579 2013-06-14
FR1355579A FR3006897A1 (fr) 2013-06-14 2013-06-14 Utilisation cosmetique ou therapeutique, notamment dermatologique de la dermicidine, analogues ou fragments de celle-ci pour prevenir l'apparition d'imperfections, ainsi que pour le traitement et le diagnostic de la peau acneique ou a tendance acneique

Publications (2)

Publication Number Publication Date
WO2014199106A2 WO2014199106A2 (fr) 2014-12-18
WO2014199106A3 true WO2014199106A3 (fr) 2015-04-09

Family

ID=51355553

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2014/051479 Ceased WO2014199106A2 (fr) 2013-06-14 2014-06-16 Utilisation cosmétique de la dermicidine, analogues ou fragments de celle-ci pour la prévention et/ou le traitement et le diagnostic de la peau grasse et des désordres esthétiques cutanés qui y sont associés

Country Status (3)

Country Link
US (1) US20160361384A1 (fr)
EP (1) EP3007718A2 (fr)
WO (1) WO2014199106A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2741535C1 (ru) * 2020-09-21 2021-01-26 Елена Сергеевна Грецова Способ ухода за жирной кожей

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3360891B1 (fr) 2017-02-14 2022-03-30 Karlsruher Institut für Technologie Peptides de pénétration cellulaire d'origine humaine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2181703A1 (fr) * 2008-10-28 2010-05-05 L'oreal Utilisation d'un lysat de microorganisme pour le traitement des peaux grasses
WO2011036174A1 (fr) * 2009-09-25 2011-03-31 B.R.A.I.N. Biotechnology Research And Information Network Ag Nouveau procédé de production d'un peptide antimicrobien
WO2012038929A1 (fr) * 2010-09-24 2012-03-29 L'oreal Utilisation cosmetique de la dermcidine, analogues ou fragments de celle-ci

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2181703A1 (fr) * 2008-10-28 2010-05-05 L'oreal Utilisation d'un lysat de microorganisme pour le traitement des peaux grasses
WO2011036174A1 (fr) * 2009-09-25 2011-03-31 B.R.A.I.N. Biotechnology Research And Information Network Ag Nouveau procédé de production d'un peptide antimicrobien
WO2012038929A1 (fr) * 2010-09-24 2012-03-29 L'oreal Utilisation cosmetique de la dermcidine, analogues ou fragments de celle-ci

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE UniProt [online] 29 May 2013 (2013-05-29), "RecName: Full=Dermcidin; EC=3.4.-.-; AltName: Full=Preproteolysin; Contains: RecName: Full=Survival-promoting peptide; Contains: RecName: Full=DCD-1;", XP002721968, retrieved from EBI accession no. UNIPROT:P81605 Database accession no. P81605 *
FLAD T ET AL: "Detection of dermcidin-derived peptides in sweat by ProteinChip(R) Technology", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 270, no. 1, 1 December 2002 (2002-12-01), pages 53 - 62, XP004387984, ISSN: 0022-1759 *
H. STEFFEN ET AL: "Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 50, no. 8, 1 August 2006 (2006-08-01), pages 2608 - 2620, XP055108670, ISSN: 0066-4804, DOI: 10.1128/AAC.00181-06 *
HYUN-HO JUNG ET AL: "Analysis of the solution structure of the human antibiotic peptide dermcidin and its interaction with phospholipid vesicles", BMB REPORTS, vol. 43, no. 5, 31 May 2010 (2010-05-31), pages 362 - 368, XP055108498, ISSN: 1976-6696, DOI: 10.3858/BMBRep.2010.43.5.362 *
JOCHEN WIESNER ET AL: "Antimicrobial peptides: The ancient arm of the human immune system", VIRULENCE, 1 September 2010 (2010-09-01), United States, pages 440 - 464, XP055148143, Retrieved from the Internet <URL:http://www.landesbioscience.com/journals/virulence/article/12983/10.4161/> DOI: 10.4161/viru.1.5.12983 *
KENSHI YAMASAKI ET AL: "Antimicrobial peptides in human skin disease", EUROPEAN JOURNAL OF DERMATOLOGY, JOHN LIBBEY EUROTEXT, FR, vol. 18, no. 1, 1 January 2008 (2008-01-01), pages 11 - 21, XP008155460, ISSN: 1167-1122, DOI: 10.1684/EJD.2008.0304 *
LAI Y-P ET AL: "Functional and structural characterization of recombinant dermcidin-1L, a human antimicrobial peptide", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 328, no. 1, 4 March 2005 (2005-03-04), pages 243 - 250, XP004723765, ISSN: 0006-291X, DOI: 10.1016/J.BBRC.2004.12.143 *
SCHITTEK BIRGIT ET AL: "The role of antimicrobial peptides in human skin and in skin infectious diseases", DRUG TARGETS - INFECTIOUS DISORDERS, BENTHAM SCIENCE PUBLISHERS LTD, NL, vol. 8, no. 3, 1 September 2008 (2008-09-01), pages 135 - 143, XP009127222, ISSN: 1871-5265 *
T YOSHINO ET AL: "Reduced expression of dermicidin, a peptide active against Propionibacterum acnes, in the sweat of acne vulgaris patients", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 130, no. S1, 1 April 2010 (2010-04-01), pages S123, XP055108880, ISSN: 0022-202X, DOI: http://dx.doi.org/10.1038/jid.2010.71 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2741535C1 (ru) * 2020-09-21 2021-01-26 Елена Сергеевна Грецова Способ ухода за жирной кожей

Also Published As

Publication number Publication date
WO2014199106A2 (fr) 2014-12-18
US20160361384A1 (en) 2016-12-15
EP3007718A2 (fr) 2016-04-20

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