WO2015019194A3 - Systems, methods and devices for electrochemical detection using helper oligonucleotides - Google Patents

Systems, methods and devices for electrochemical detection using helper oligonucleotides Download PDF

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Publication number
WO2015019194A3
WO2015019194A3 PCT/IB2014/002522 IB2014002522W WO2015019194A3 WO 2015019194 A3 WO2015019194 A3 WO 2015019194A3 IB 2014002522 W IB2014002522 W IB 2014002522W WO 2015019194 A3 WO2015019194 A3 WO 2015019194A3
Authority
WO
WIPO (PCT)
Prior art keywords
systems
methods
devices
electrochemical detection
helper oligonucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2014/002522
Other languages
French (fr)
Other versions
WO2015019194A2 (en
Inventor
Graham D. JACK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xagenic Inc
Original Assignee
Xagenic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xagenic Inc filed Critical Xagenic Inc
Priority to CN201480055373.7A priority Critical patent/CN105593379A/en
Priority to CA2920419A priority patent/CA2920419A1/en
Priority to EP14834013.6A priority patent/EP3030678A4/en
Publication of WO2015019194A2 publication Critical patent/WO2015019194A2/en
Publication of WO2015019194A3 publication Critical patent/WO2015019194A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Disclosed herein are systems, devices, and methods for the electrochemical detection of a target using a helper oligonucleotide (each a helper oligo, or collectively, helper oligos).
PCT/IB2014/002522 2013-08-07 2014-08-07 Systems, methods and devices for electrochemical detection using helper oligonucleotides Ceased WO2015019194A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201480055373.7A CN105593379A (en) 2013-08-07 2014-08-07 Systems, methods and devices for electrochemical detection using helper oligonucleotides
CA2920419A CA2920419A1 (en) 2013-08-07 2014-08-07 Systems, methods and devices for electrochemical detection using helper oligonucleotides
EP14834013.6A EP3030678A4 (en) 2013-08-07 2014-08-07 Systems, methods and devices for electrochemical detection using helper oligonucleotides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361863280P 2013-08-07 2013-08-07
US61/863,280 2013-08-07

Publications (2)

Publication Number Publication Date
WO2015019194A2 WO2015019194A2 (en) 2015-02-12
WO2015019194A3 true WO2015019194A3 (en) 2015-07-02

Family

ID=52449149

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/002522 Ceased WO2015019194A2 (en) 2013-08-07 2014-08-07 Systems, methods and devices for electrochemical detection using helper oligonucleotides

Country Status (6)

Country Link
US (1) US20150045254A1 (en)
EP (1) EP3030678A4 (en)
CN (1) CN105593379A (en)
CA (1) CA2920419A1 (en)
HK (1) HK1226104A1 (en)
WO (1) WO2015019194A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9506908B2 (en) 2014-10-06 2016-11-29 Alveo Technologies, Inc. System for detection of analytes
US10196678B2 (en) 2014-10-06 2019-02-05 ALVEO Technologies Inc. System and method for detection of nucleic acids
US9921182B2 (en) 2014-10-06 2018-03-20 ALVEO Technologies Inc. System and method for detection of mercury
US10627358B2 (en) * 2014-10-06 2020-04-21 Alveo Technologies, Inc. Method for detection of analytes
US10352899B2 (en) * 2014-10-06 2019-07-16 ALVEO Technologies Inc. System and method for detection of silver
US10597719B2 (en) 2015-03-24 2020-03-24 National University Corporation Gunma University Detection kit and simple method for detecting target nucleic acids
WO2016170179A1 (en) 2015-04-24 2016-10-27 Qiagen Gmbh Method for immobilizing a nucleic acid molecule on solid support
ES2940189T3 (en) * 2015-04-24 2023-05-04 Miltenyi Biotec Bv & Co Kg Method for hybridizing a nucleic acid molecule
US11085073B2 (en) 2015-04-24 2021-08-10 Qiagen Gmbh Method for immobilizing a nucleic acid molecule on a solid support
EP3472355A4 (en) 2016-06-15 2020-07-29 Genecapture, Inc. COMPOSITIONS, METHODS AND DEVICES WITH HAIRPIN STRUCTURE CATCHER MOLECULES
ES3008759T3 (en) * 2016-08-02 2025-03-25 Hoffmann La Roche Helper oligonucleotide for improving efficiency of amplification and detection/quantitation of nucleic acids
KR20220151011A (en) 2016-09-23 2022-11-11 알베오 테크놀로지스 인크. Methods and compositions for detecting analytes
CN107049587A (en) * 2017-05-14 2017-08-18 郭宝煊 Intelligent menstrual cup
JP2022516443A (en) 2018-12-20 2022-02-28 アルヴェオ テクノロジーズ インコーポレイテッド Portable diagnostic inspection system for impedance-based analysis detection
US12472492B2 (en) 2020-08-14 2025-11-18 Alveo Technologies, Inc. Systems and methods of sample depositing and testing
WO2022036005A2 (en) * 2020-08-14 2022-02-17 Alveo Technologies, Inc. Nucleic acids for detection of infectious agents

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US20050053962A1 (en) * 1998-01-27 2005-03-10 Gary Blackburn Amplification of nucleic acids with electronic detection
WO2000004193A1 (en) * 1998-07-20 2000-01-27 Yale University Method for detecting nucleic acids using target-mediated ligation of bipartite primers
US6942771B1 (en) * 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
IL138229A (en) * 2000-09-04 2005-03-20 Yissum Res Dev Co Method and system for detecting nucleic acids
EP1478783A4 (en) * 2002-02-06 2006-12-27 Ge Healthcare Bio Sciences Ab COMPOSITIONS AND METHODS FOR ROLLING CIRCLE AMPLIFICATION
EP1687406B1 (en) * 2003-11-10 2010-01-27 Geneohm Sciences, Inc. Nucleic acid detection method having increased sensitivity
CA2547804A1 (en) * 2003-12-08 2005-06-30 F. Hoffmann-La Roche Ag Novel thiazole derivatives
US7763426B2 (en) * 2004-11-01 2010-07-27 The Regents Of The University Of California Probes and methods for detection of Escheridia coli and antibiotic resistance
WO2007120299A2 (en) * 2005-11-29 2007-10-25 The Regents Of The University Of California Signal-on architecture for electronic, oligonucleotide-based detectors
WO2010060060A1 (en) * 2008-11-24 2010-05-27 Adnavance Technologies, Inc. Electrochemical methods of detecting nucleic acid hybridization

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BARKEN, K.B. ET AL.: "Effect of unlabeled helper probes on detection of an RNA target by bead-based sandwich hybridization.", BIOTECHNIQUES, vol. 36, no. 1, January 2004 (2004-01-01), pages 124 - 132, XP001538550 *
LI, J. ET AL.: "Efficient detection of secondary structure folded nucleic acids related to Alzheimer's disease based on junction probes.", BIOSENSORS AND BIOELECTRONICS, vol. 36, 21 April 2012 (2012-04-21), pages 142 - 146, XP028511803 *
METFIES, K. ET AL.: "Electrochemical detection of the toxic dinoflagellate Alexandrium ostenfeldii with a DNA-biosensor.", BIOSENSORS AND BIOELECTRONICS, vol. 20, 7 July 2004 (2004-07-07), pages 1349 - 1357, XP027619294 *
PEPLIES, J. ET AL.: "Optimization strategies for DNA microarray-based detection of bacteria with 16S rRNA-targeting oligonucleotide probes.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 69, no. 3, March 2003 (2003-03-01), pages 1397 - 1407, XP055318069 *

Also Published As

Publication number Publication date
CA2920419A1 (en) 2015-02-12
EP3030678A4 (en) 2017-05-10
CN105593379A (en) 2016-05-18
WO2015019194A2 (en) 2015-02-12
US20150045254A1 (en) 2015-02-12
EP3030678A2 (en) 2016-06-15
HK1226104A1 (en) 2017-09-22

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