WO2017181967A1 - 预填充笔式注射器 - Google Patents

预填充笔式注射器 Download PDF

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Publication number
WO2017181967A1
WO2017181967A1 PCT/CN2017/081254 CN2017081254W WO2017181967A1 WO 2017181967 A1 WO2017181967 A1 WO 2017181967A1 CN 2017081254 W CN2017081254 W CN 2017081254W WO 2017181967 A1 WO2017181967 A1 WO 2017181967A1
Authority
WO
WIPO (PCT)
Prior art keywords
wall
cylinder
disposed
rotating
barrel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2017/081254
Other languages
English (en)
French (fr)
Inventor
王春生
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Gangan Technology Co Ltd
Original Assignee
Beijing Gangan Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Gangan Technology Co Ltd filed Critical Beijing Gangan Technology Co Ltd
Priority to ES17785451T priority Critical patent/ES2815425T3/es
Priority to US16/095,349 priority patent/US11052197B2/en
Priority to EP17785451.0A priority patent/EP3446733B1/en
Publication of WO2017181967A1 publication Critical patent/WO2017181967A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms

Definitions

  • the invention relates to the field of diabetes human insulin injection technology, in particular to a pre-filled pen injector.
  • Diabetes is a group of metabolic diseases characterized by high blood sugar. Hyperglycemia is caused by defects in insulin secretion or its biological effects, or both. There are many treatments for diabetes, including medication, exercise therapy, diet therapy, and more. Among them, insulin injection therapy in drug therapy is the most common and effective treatment method, which requires patients to regularly and quantitatively inject insulin. Therefore, the injection pen becomes a tool for the patient to inject insulin himself.
  • the injection pen of the prior art includes a medicine pipe, a coil, a clutch pipe, a screw, and a nut pipe.
  • One end of the screw is provided with a piston, and the piston is disposed in the medicine water pipe.
  • the other end of the screw is disposed in the nut tube, the nut tube is provided with a clutch tube, and the clutch tube is provided with a coil.
  • turn the coil, and the coil will drive the clutch tube to move axially until the desired position.
  • the nut tube is rotated, and the nut tube drives the screw to move and pushes the piston to move in the medicine pipe for injection.
  • the user performs a quantitative injection by adjusting the position of the clutch tube each time the injection is performed.
  • the user adjusts the scale value by adjusting the position of the clutch tube. After the medicine in the medicine tube is injected, the user can still move the clutch tube to adjust the scale value through the coil.
  • the prior art injection pen can still adjust the scale value after the injection of the medicine water in the medicine water pipe, so that the user cannot accurately know whether the medicine is injected or not.
  • the prefilled pen injector comprises: a screw, a memory connecting cylinder, a fixed cylinder and a rotating cylinder; on one end surface of the rotating cylinder, a plurality of first one-way teeth are evenly arranged around the axis of the rotating cylinder
  • the opening of the rotating cylinder near one end of the first one-way tooth is a waist hole
  • the memory tube is disposed in the rotating cylinder, and the inner wall of the memory barrel is provided with a protrusion matching the thread of the screw
  • a pawl matched with the first one-way tooth, and the fixed cylinder is provided with a first internal thread matched with the screw
  • on the screw two cutting surfaces are oppositely arranged along the direction of the screw extension, and one end of the screw is disposed
  • There is a piston, and a stopper is arranged in the screw groove at the other end, and the stopper is used to block the rotation of the memory cylinder relative to the screw.
  • the pre-filled pen injector further comprises a fixed housing, a scale drum and a top cap tube;
  • the outer wall of the fixing tube is provided with a first fixing protrusion;
  • the fixed housing is a hollow shell with two ends open, fixed a second internal thread is disposed on the inner wall of the casing, and a first groove is formed on the inner wall of the other end to cooperate with the first fixing protrusion;
  • the outer wall of the scale drum is provided with the first inner thread corresponding to the second internal thread External thread, the inner wall of the scale drum is provided with a rotating protrusion;
  • the top hat tube is disposed in the scale drum, and the outer wall of the top hat barrel is provided with a second groove that engages with the rotating protrusion;
  • a sliding groove is disposed on the inner wall of the cap connecting barrel in a direction in which the top cap is extended; the end of the memory connecting barrel away from the fixed cylinder is provided with a sliding protrusion that cooperates with the sliding groove.
  • the pre-filled pen injector further includes a top cap, a spring, a single-sided one-way gear, and a double-faced one-way gear with two teeth facing each other obliquely;
  • a rotating strip is arranged in the direction in which the rotating cylinder extends;
  • the inner wall of the scale rotating cylinder near one end of the fixed cylinder is provided with an annular boss, and the annular boss is centered on the axis of the scale drum, evenly surrounding a plurality of second one-way teeth;
  • the double-sided one-way gear is sleeved on the rotating cylinder, one side of which cooperates with the single-sided one-way gear, and the other side cooperates with the second one-way tooth;
  • a third groove corresponding to the rotating strip is disposed on the inner wall of the gear, and a side of the single-sided one-way tooth away from the double-sided one-way tooth abuts against one end of the top-capped cylinder;
  • the other end of the top-capped barrel is provided with an end surface a connecting plate, a side of the connecting plate away from the top cap connecting cylinder is provided with a sleeve, and a circumferential surface of the connecting plate is provided with
  • the top cap is a hollow shell open at one end, the inner end surface of the top cap is provided with a cylinder body; the cylinder body is disposed in the sleeve; the spring sleeve is disposed outside the sleeve, one end of which is abutted against the connecting disc, and the other end is top The inner end surface of the cap abuts.
  • the fixed casing comprises an outer cylinder and an observation cylinder; the inner wall of one end of the outer cylinder is provided with a card slot, the inner wall of the other end is provided with a first groove, and the outer cylinder is provided with a viewing port; and the outer wall of one end of the observation cylinder is provided with The card slot is provided with a matching protrusion, and the observation tube is provided with a notch at a position corresponding to the observation port, the notch is in communication with the observation port, and the second internal thread is disposed in the observation tube.
  • an end of the scale drum adjacent to the top cap is provided with an annular rotating portion that is open at both ends, the annular rotating portion is sleeved outside the top cap, and the rotating protrusion is disposed on the inner wall of the annular rotating portion.
  • the outer wall of the top cap is provided with an annular groove
  • the inner wall of the annular rotating portion is provided with a first annular protrusion
  • the first annular protrusion is disposed in the annular groove
  • the first annular protrusion and the side wall of the annular groove There is a gap between them.
  • the pre-filled pen injector further comprises a vial and a needle; the vial is open at one end, the other end is inserted with a needle, and the needle is connected with the vial; the piston is disposed in the vial, and the circumferential surface of the piston and the inner wall of the vial are Abut.
  • the pre-filled pen injector further includes a medicine bottle protection tube; the second inner fixing wall is disposed on an inner wall of one end of the outer tube near the fixed tube; the medicine bottle protection tube is open at both ends, and the medicine bottle protection tube is sleeved outside the medicine bottle A fourth groove is formed on the outer wall of one end of the fixed cylinder to be engaged with the second fixing protrusion.
  • the medicine bottle casing is provided with a second external thread on an outer wall of one end of the fixed cylinder;
  • the needle includes a needle body and a rotating cylinder;
  • the rotating cylinder has one end opening, and the inner wall is provided with a second external thread a matching third internal thread;
  • the needle body is inserted at one end of the rotating barrel and communicated with the vial.
  • the pre-filled pen injector further includes a cap; the cap is a hollow shell that is open at one end, and the inner wall of the cap is provided with a second annular protrusion; and the outer wall of the vial is provided with a second annular protrusion Ring groove.
  • the prefilled pen injector provided by the invention has a fixed fixing cylinder when the user is in use, and rotates the memory cylinder clockwise by a certain number of turns. Since the first one-way tooth and the pawl are locked in a clockwise direction, the rotating cylinder is rotated. And the screw in the rotating cylinder does not move, the memory connecting cylinder moves a certain distance with respect to the axial direction of the screw, and the scale is adjusted.
  • the user rotates the rotating cylinder counterclockwise, the rotating cylinder drives the screw and the memory cylinder on the screw rotates, and the screw and the memory cylinder rotate according to the fixed cylinder, and move the same distance in the opposite axial direction with respect to the fixed cylinder.
  • the screw pushes the piston to move and completes a certain dose of injection.
  • the user rotates the memory tube clockwise again, and the memory tube moves again a certain distance relative to the screw.
  • the protrusion in the memory tube abuts against the stopper on the screw, and the block blocks the memory tube from rotating relative to the screw, that is, at this time, the user cannot rotate the memory tube clockwise, thereby notifying The user has finished using the potion.
  • the user after the medicinal water is used, the user cannot rotate the memory splicing adjustment scale clockwise, so that the user can know that the syrup in the injection pen has been used.
  • FIG. 1 is an assembled view of a prefilled pen injector according to an embodiment of the present invention
  • FIG. 2 is a schematic structural view of a part of a prefilled pen injector according to an embodiment of the present invention
  • FIG. 3 is a schematic structural view of a rotating cylinder and a fixed cylinder in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 4 is a schematic structural view of a fixed cylinder in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 5 is a schematic structural view of a rotating cylinder in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 6 is a schematic structural view of a screw in a prefilled pen injector according to an embodiment of the present invention.
  • FIG. 7 is a schematic structural view of a rotating cylinder and a screw in a prefilled pen injector according to an embodiment of the present invention.
  • FIG. 8 is a schematic structural view of a top cap barrel, a memory barrel, and a screw in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 9 is a schematic structural view of a scale drum and a top hat barrel in a prefilled pen injector according to an embodiment of the present invention.
  • FIG. 10 is a schematic structural view of a single-sided one-way gear in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 11 is a schematic structural view of a double-sided one-way gear in a prefilled pen injector according to an embodiment of the present invention.
  • FIG. 12 is a schematic structural view of an observation cylinder in a prefilled pen injector according to an embodiment of the present invention.
  • FIG. 13 is a schematic structural view of an outer cylinder of a prefilled pen injector according to an embodiment of the present invention.
  • installation In the description of the present invention, it should be noted that the terms “installation”, “connected”, and “connected” are to be understood broadly, and, for example, may be fixed connections, unless explicitly stated and defined otherwise. It can also be a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and can be internal communication between the two elements.
  • detachable connection or an integral connection
  • it can be a mechanical connection or an electrical connection
  • the specific meaning of the above terms in the present invention can be understood in a specific case by those skilled in the art.
  • FIG. 1 is a schematic structural view of a prefilled pen injector according to an embodiment of the present invention
  • FIG. 2 is a schematic structural view of a prefilled pen injector according to an embodiment of the present invention
  • FIG. 3 is a prefilled pen type according to an embodiment of the present invention
  • FIG. 4 is a schematic structural view of a fixed cylinder in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 5 is a rotating cylinder of a prefilled pen injector according to an embodiment of the present invention
  • FIG. 6 is a schematic structural view of a screw in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 1 is a schematic structural view of a prefilled pen injector according to an embodiment of the present invention
  • FIG. 2 is a schematic structural view of a prefilled pen injector according to an embodiment of the present invention
  • FIG. 3 is a prefilled pen type according to an embodiment of the present invention
  • FIG. 4 is a schematic structural view of a fixed cylinder
  • the pre-filled pen injector provided in this embodiment includes: a screw 4, a memory barrel 5, a fixed barrel 12, and a rotating barrel 11; on one end surface of the rotating barrel 11, to rotate the barrel 11
  • the axis is centered, and a plurality of first one-way teeth 18 are evenly arranged;
  • the opening of the rotating cylinder 11 near one end of the first one-way tooth 18 is a waist-shaped hole 28;
  • the memory tube 5 is disposed in the rotating cylinder 11, and the memory is connected
  • the inner wall of the 5 is provided with a protrusion 41 matching the thread of the screw 4;
  • the end surface of the fixed barrel 12 is provided with a pawl 19 which cooperates with the first one-way tooth 18, and the fixed barrel 12 is provided with a screw 4 a matching first internal thread 24; on the screw 4, in the direction in which the screw 4 extends, two cutting faces 42 are oppositely
  • the two cut faces 42 of the screw 4 are parallel to the plane of the waist hole 28, and the screw 4 is axially movable within the waist hole 28.
  • the number of the pawls 19 may be one or more than two.
  • the number of the pawls 19 is two, and the two pawls 19 are symmetrically disposed on one end surface of the fixed cylinder 12. The engagement of the two pawls 19 with the first one-way teeth 18 allows the first one-way teeth 18 to be more stable during rotation.
  • the prefilled pen injector provided by the present invention in use, the user fixes the fixed cylinder 12, rotates the memory cylinder 5 clockwise by a certain number of turns, because the first one-way tooth 18 and the pawl 19 are locked in a clockwise direction Therefore, the rotating cylinder 11 and the screw 4 in the rotating cylinder 11 are not moved, and the memory cylinder 5 is axially moved by a certain distance with respect to the screw 4, and the scale is adjusted.
  • the user rotates the rotating cylinder 11 counterclockwise. Since the first one-way tooth 18 and the pawl 19 are not locked in the counterclockwise direction, the rotating cylinder 11 drives the screw 4 and the memory cylinder 5 on the screw 4 to rotate.
  • the screw 4 and the memory cylinder 5 rotate and move the same distance in the opposite axial direction with respect to the fixed cylinder 12, while the screw 4 pushes the piston 13 to move, completing a certain dose of injection.
  • the user turns the memory barrel 5 clockwise again, and the memory barrel 5 moves again a certain distance with respect to the screw 4.
  • the protrusion 41 in the memory barrel 5 abuts against the stopper 29 on the screw 4, and the stopper 29 blocks the rotation of the memory barrel 5 relative to the screw 4, that is, at this time, the user cannot clockwise.
  • the memory cartridge 5 is rotated to inform the user that the syrup has been used.
  • the user after the medicinal water is used, the user cannot rotate the memory splicing cylinder 5 to adjust the scale clockwise, so that the user can know that the syrup in the syringe has been used.
  • FIG. 8 is a schematic structural view of a top cap barrel, a memory barrel and a screw in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 9 is a schematic diagram of a scale drum and a top hat barrel in an injection pen according to an embodiment of the present invention
  • Schematic diagram of the structure as shown in FIG.
  • the pre-filled pen injector further comprises a fixed housing, a scale drum 8 and a top cap barrel 3; the outer wall of the fixed barrel 12
  • the first fixing protrusion 20 is disposed;
  • the fixing housing is a hollow housing having two ends open, the inner wall of the fixing housing is provided with a second internal thread, and the other end inner wall is provided with the first fixing protrusion 20 a first groove;
  • the outer wall of the scale drum 8 is provided with a first external thread 25 matched with the second internal thread, and the inner wall of the scale drum 8 is provided with a rotation convex 17;
  • the top cap barrel 3 is disposed in the scale drum 8, and the outer wall of the top hat barrel 3 is provided with a second groove that engages with the rotation protrusion 17;
  • the top hat is connected to the inner wall of the barrel 3,
  • a sliding groove 22 is disposed in a direction in which the top cap connecting cylinder 3 extends; and one end of the memory connecting barrel 5 away from the fixed cylinder is provided with a sliding pro
  • the shape of the first fixing protrusion 20 may be various, for example, a square shape, a circular shape, a ring shape, or the like.
  • the number of the first fixing protrusions 20 and the first grooves may be one or more than two.
  • the user when in use, the user holds the fixed housing, rotates the scale drum 8 clockwise, and the fixed housing and the fixed cylinder 12 do not move. Because the scale drum 8 and the fixed housing have a threaded relationship, the scale The rotating drum 8 rotates relative to the fixed casing and moves axially a certain distance. At the same time, the scale rotating drum 8 drives the top cap connecting cylinder 3 to rotate and moves in the axial direction, and the top cap connecting cylinder 3 drives the memory connecting cylinder 5 to rotate relative to the screw 4 The axis moves a certain distance and the scale is adjusted. The user turns the rotating cylinder 11 counterclockwise to complete the injection.
  • the user can rotate the scale drum 8 to realize the rotation of the memory barrel 5 relative to the screw 4, that is, by fixing the housing and rotating the scale.
  • the cooperation of the barrel 8 and the top cap tube 3 realizes the adjustment of the scale, which is convenient for the user to use.
  • the fixed casing prevents the scale drum 8 and the top hat barrel 3 from falling into the dust, thereby keeping the injection pen member clean.
  • FIG. 10 is a schematic structural view of a single-sided one-way gear in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 11 is a schematic structural view of a double-sided one-way gear in a prefilled pen injector according to an embodiment of the present invention
  • 1-11 based on the above embodiment, further, the pre-filled pen injector further comprises a top cap 1, a spring 2, a single-sided one-way gear 6 and a double-sided one-way gear with two teeth intersecting each other obliquely.
  • the double-sided one-way gear 7 is sleeved on the rotating cylinder 11, one side of which cooperates with the single-sided one-way gear 6, and the other side cooperates with the second one-way tooth;
  • a third groove 23 is formed on the inner wall of the gear 6 to cooperate with the rotating bar 27, and one side of the one-sided one-way tooth away from the double-sided one-way tooth abuts against one end of the top cap connecting cylinder 3;
  • the top cap is connected to the cylinder 3
  • a connecting plate is disposed on the end surface of the other end, and a sleeve is disposed on a side of the connecting plate away from the top cap connecting cylinder 3, and a groove matching the rotating protrusion 17 is disposed on the circumferential surface of the connecting plate;
  • the top cap 1 is open at one end a hollow casing, the inner end surface of the top cap 1 is provided with a cylinder;
  • the cylinder is disposed in the sleeve;
  • the spring 2 is
  • the double-sided one-way gear 7 is a hollow shell open at both ends, and the end faces of the two ends are centered on the axis of the double-sided one-way gear 7, and a plurality of one-way teeth are evenly arranged, and both ends are respectively The one-way teeth on the end faces are inclined in an oblique direction.
  • the single-faced one-way gear 6 is a hollow casing that is open at both ends, and one end face is centered on the axis of the single-sided one-way gear 6, and a plurality of one-way teeth are evenly arranged.
  • the user when in use, the user holds the fixed housing, rotates the scale drum 8 clockwise, the scale drum 8 rotates and moves in the axial direction, and the scale drum 8 drives the top hat tube 3 and the top
  • the cap barrel 3 drives the memory barrel 5 to rotate and moves in the axial direction.
  • the double-sided one-way gear 7 and one side The teeth between the one-way gears 6 are in a locked state, and at the same time, the single-sided one-way gear 6 and the rotating cylinder 11 have a cooperation of the rotating strip 27 and the third recess 23, and therefore, the double-sided one-way gear 7 and the single-sided single The gear 6 is simultaneously moved in the axial direction without rotation, and simultaneously pushes the top cap barrel 3 to move axially.
  • the user presses down on the top cap 1 so that the top cap cylinder 3, the double-sided one-way gear 7 and the single-sided one-way gear 6 have no gap, so that the spring 2 has no bounce space, the first one-way The tooth 18 and the double-sided one-way tooth cannot generate tooth bounce.
  • the user rotates the scale drum 8 counterclockwise, and the scale drum 8 drives the single-sided one-way gear 6 to rotate by the double-sided one-way gear 7.
  • the one-side one-way gear 6 drives the rotating cylinder 11 to rotate, and the rotating cylinder 11 drives the screw 4 Rotate and move in the opposite axial direction.
  • the scale drum 8 drives the top cap barrel 3 to rotate and moves in the opposite axial direction, and the top cap 1 connects the cylinder 3 to rotate the memory barrel 5 and moves in the opposite axial direction. Since the angular velocity of the screw 4 and the memory cylinder 5 are the same at this time, the screw 4 and the memory cylinder 5 are simultaneously rotated and moved in the opposite axial direction, and the screw 4 pushes the piston 13 to move, completing the injection.
  • the double-sided one-way gear 7 and the single-sided one-way gear 6 are disposed on the rotating cylinder 11, and the user can rotate the scale drum 8 to complete the adjustment of the scale and the injection of the medicine, and the operation is convenient.
  • the beating of the teeth between the double-sided one-way gear 7 and the first one-way tooth 18 can facilitate the user to control the rotation force when rotating the scale drum 8 to facilitate the adjustment of the scale.
  • FIG. 12 is a schematic structural view of an observation cylinder in a prefilled pen injector according to an embodiment of the present invention
  • FIG. 13 is a schematic structural view of an outer cylinder in a prefilled pen injector according to an embodiment of the present invention.
  • the fixed housing further includes an outer cylinder 10 and an observation cylinder 9 ; the inner wall of one end of the outer cylinder 10 is provided with a card slot 32 .
  • the inner wall of the other end is provided with a first groove, and the outer tube 10 is provided with a viewing port 33; the outer wall of one end of the observation tube 9 is provided with a locking protrusion 30 matched with the card slot 32, and the observation tube 9 is opposite to the observation port 33.
  • a notch 31 is provided at the corresponding position, the notch 31 is in communication with the observation port 33, and the second internal thread is provided in the observation cylinder 9.
  • the fixed casing is disposed as the outer cylinder 10 and the observation cylinder 9, and the observation port 33 is disposed on the outer cylinder 10, and the notch 31 is disposed on the observation cylinder 9, which is convenient for the user to observe the scale drum 8 to be removed. The distance is convenient for observing the scale value.
  • the end of the top reel 8 adjacent to the top cap 1 is provided with an annular rotating portion 26 which is open at both ends, and the annular rotating portion 26 is sleeved outside the top cap 1 .
  • the rotation projection 17 is provided on the inner wall of the annular rotating portion 26.
  • a plurality of protrusions may be disposed on the outer wall of the annular rotating portion 26, so that the friction between the user's hand and the annular rotating portion 26 is increased when the user holds the annular rotating portion 26 to rotate, which is convenient to use. The person turns.
  • annular rotating portion 26 is disposed on the scale drum 8, and the user can rotate the ring rotating portion 26 by rotating the ring rotating portion 26 during use to facilitate the user's operation.
  • the outer wall of the top cap 1 is provided with an annular groove
  • the inner wall of the annular rotating portion 26 is provided with a first annular protrusion, the first annular convex It is disposed in the annular groove, and has a gap between the first annular protrusion and the side wall of the annular groove.
  • the top cap barrel 3 moves in the axial direction
  • the annular groove moves relative to the first annular protrusion
  • the spring 2 compresses.
  • the annular groove moves in the opposite direction with respect to the first annular projection, and the spring 2 extends.
  • the prefilled pen injector further includes a vial 14 and a needle; the vial 14 is open at one end, the other end is inserted with a needle, and the needle and the vial are inserted. 14 is connected; the piston 13 is disposed in the vial 14 and the peripheral surface of the piston 13 abuts against the inner wall of the vial 14.
  • the user rotates the scale drum 8 clockwise to adjust the scale, and then presses the top cap 1, and rotates the scale drum 8 counterclockwise, and the piston 13 moves and pushes the medicine through the needle to the human body.
  • the syrup bottle 14 and the needle cooperate to complete the injection, and the structure is simple, and the processing and manufacture are convenient.
  • the pre-filled pen injector further includes a vial cover 15; the outer cylinder 10 is disposed on an inner wall of one end of the fixed cylinder 12.
  • a second fixing protrusion is disposed; the medicine bottle casing 15 is open at both ends, and the medicine bottle casing 15 is sleeved outside the medicine bottle 14, and the outer wall of one end of the fixing cylinder 12 is disposed to be engaged with the second fixing protrusion.
  • Fixed fourth groove is disposed
  • a medicine bottle protection cylinder 15 is disposed outside the medicine bottle 14 , and the medicine bottle protection tube 15 can protect the medicine bottle 14 , thereby preventing the medicine bottle 14 from being damaged by external force collision, thereby prolonging the service life of the injection pen. .
  • the medicine bottle casing 15 is provided with a second external thread on the outer wall of one end of the fixed cylinder 12; the needle includes a needle body and a rotating cylinder; The opening has an inner wall provided with a third internal thread that cooperates with the second external thread; the needle body is inserted at one end of the rotating barrel and is in communication with the vial 14.
  • the detachment of the two is achieved by the screw connection between the rotating cylinder and the vial guard 15 to facilitate the user to install the needle.
  • the prefilled pen injector further includes a cap 16; the cap 16 is a hollow housing that is open at one end, and the inner wall of the cap 16 is provided with a second An annular protrusion; an annular groove of the second annular protrusion is disposed on the outer wall of the medicine bottle casing.
  • the user pulls the cap 16 from the vial of the vial, rotates the scale drum 8 clockwise to adjust the scale, presses the top cap 1, and rotates the scale drum 8 counterclockwise to complete the injection.
  • the cap 16 when the user does not use the syringe, the cap 16 is sleeved outside the vial of the vial, which prevents the needle from falling into dust and other impurities, and ensures the cleanliness of the syringe during use.

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  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
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  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

一种用于注射胰岛素的预填充笔式注射器，包括：螺杆（4）、记忆连筒（5）、固定筒（12）以及转动筒（11）。转动筒（11）的一端端面上，以转动筒（11）的轴线为中心，均匀围设有多个第一单向齿（18）；转动筒（11）靠近第一单向齿（18）一端的开口为腰形孔（28）；记忆连筒（5）设置在转动筒（11）内，记忆连筒（5）的内壁上设置有与螺杆（4）的螺纹相配合的凸起（41）；固定筒（12）一端端面上设置有与第一单向齿（18）相配合的棘爪（19），且固定筒（12）上设置有与螺杆（4）相配合的第一内螺纹（24）；螺杆（4）上设置有两个切面（42），螺杆（4）的一端设置有活塞（13），另一端的螺槽内设置有挡块（29），挡块（29）用于阻挡记忆连筒（5）相对螺杆（4）转动。当药水使用完毕后，使用者不能顺时针转动记忆连筒（5）调整刻度，从而使用者可得知注射器内的药水已经使用完毕。

Description

预填充笔式注射器
本申请要求于2016年04月21日提交中国专利局的申请号为CN201610258059.X、名称为“预填充笔式注射器”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本发明涉及糖尿病人胰岛素注射技术领域，尤其是涉及一种预填充笔式注射器。
背景技术
糖尿病是一组以高血糖为特征的代谢性疾病。高血糖则是由于胰岛素分泌缺陷或其生物作用受损，或两者兼有引起。糖尿病的治疗方法有多种，包括药物治疗、运动治疗、饮食治疗等等。其中药物治疗中的胰岛素注射治疗方法是最常见和最有效的治疗方法，该方法需要患者定期定量地注射胰岛素。因此，注射笔成为患者自己进行注射胰岛素的工具。
现有技术中的注射笔包括药水管、旋管、离合管、螺杆以及螺母管。螺杆的一端设置有活塞，活塞设置在药水管内。螺杆的另一端穿设在螺母管内，螺母管外套设离合管，离合管外套设旋管。当需要调节注射计量时，转动旋管，旋管带动离合管延轴向移动，直至所需位置。调节完毕后，旋转螺母管，螺母管带动螺杆移动并推动活塞在药水管内移动进行注射。使用者每次注射时通过调整离合管位置来进行定量注射。
但是，现有技术中的注射笔，使用者通过调整离合管的位置调整刻度值，当药水管内的药水注射完毕后，使用者仍可通过旋管带动离合管轴向移动调整刻度值，而此时使用者已不能进行注射，因此，现有技术中的注射笔在药水管的药水注射完毕后仍可进行刻度值调整，从而使得使用者不能准确获知药水是否注射完毕。
发明内容
本发明的目的在于提供一种预填充笔式注射器，以解决现有技术中存在的使用者不能准确获知药水是否注射完毕的技术问题。
本发明提供的预填充笔式注射器，包括：螺杆、记忆连筒、固定筒以及转动筒；转动筒的一端端面上，以转动筒的轴线为中心，均匀围设有多个第一单向齿；转动筒靠近第一单向齿一端的开口为腰形孔；记忆连筒设置在转动筒内，记忆连筒的内壁上设置有与螺杆的螺纹相配合的凸起；固定筒一端端面上设置有与第一单向齿相配合的棘爪，且固定筒上设置有与螺杆相配合的第一内螺纹；螺杆上，沿螺杆延伸的方向，相对地设置有两个切面，螺杆的一端设置有活塞，另一端的螺槽内设置有挡块，挡块用于阻挡记忆连筒相对螺杆转动。
进一步地，预填充笔式注射器还包括固定壳体、刻度转筒和顶帽连筒；固定筒的外壁上设置有第一固定凸起；固定壳体为两端开口的中空壳体，固定壳体的内壁上设置有第二内螺纹，另一端内壁上设置有与第一固定凸起相配合的第一凹槽；刻度转筒的外壁上设置有与第二内螺纹相配合的第一外螺纹，刻度转筒的内壁上设置有转动凸起；顶帽连筒设置在刻度转筒内，且顶帽连筒的外壁上设置有与转动凸起相卡合的第二凹槽；顶帽连筒的内壁上，沿顶帽连筒延伸的方向，设置有滑槽；记忆连筒远离固定筒的一端设置有与滑槽相配合的滑动凸起。
进一步地，预填充笔式注射器还包括顶帽、弹簧、单面单向齿轮和两面齿倾斜方向相互交叉的双面单向齿轮；
转动筒的外壁上，延转动筒延伸的方向，设置有转动条；刻度转筒靠近固定筒一端的内壁上设置有环形凸台，环形凸台上，以刻度转筒的轴线为中心，均匀围设有多个第二单向齿；双面单向齿轮套设在转动筒上，其一面与单面单向齿轮配合，另一面与第二单向齿配合；单面单向 齿轮的内壁上设置有与转动条相配合的第三凹槽，单面单向齿远离双面单向齿的一面与顶帽连筒的一端抵接；顶帽连筒另一端端面上设置有连接盘，连接盘远离顶帽连筒的一面上设置有套筒，连接盘的周面上设置有与转动凸起相配合的凹槽；
顶帽为一端开口的中空壳体，顶帽的内端面上设置有圆柱体；圆柱体设置在套筒内；弹簧套设在套筒外，其一端与连接盘抵接，另一端与顶帽的内端面抵接。
进一步地，固定壳体包括外筒和观察筒；外筒一端内壁上设置有卡槽，另一端内壁上设置有第一凹槽，外筒上设置有观察口；观察筒一端外壁上设置有与卡槽相配合的卡设凸起，观察筒与观察口相对应的位置上设置有缺口，缺口与观察口连通，观察筒内设置有第二内螺纹。
进一步地，刻度转筒靠近顶帽的一端设置有两端开口的环形转动部，环形转动部套设在顶帽外，转动凸起设置在环形转动部的内壁上。
进一步地，顶帽的外壁上设置有环形槽，环形转动部的内壁上设置有第一环形凸起，第一环形凸起设置在环形槽内，且第一环形凸起与环形槽的侧壁之间具有间隙。
进一步地，预填充笔式注射器还包括药水瓶和针头；药水瓶一端开口，另一端插设针头，且针头与药水瓶连通；活塞设置在药水瓶内，且活塞的周面与药水瓶的内壁抵接。
进一步地，预填充笔式注射器还包括药瓶护筒；外筒靠近固定筒的一端内壁上设置有第二固定凸起；药瓶护筒两端开口，药瓶护筒套设在药水瓶外，其靠近固定筒的一端外壁上设置有与第二固定凸起相卡合固定的第四凹槽。
进一步地，药瓶护筒远离固定筒一端外壁上设置有第二外螺纹；针头包括针本体和旋转筒；旋转筒一端开口，其内壁设置有与第二外螺纹 相配合的第三内螺纹；针本体一端插设在旋转筒封闭端上，且与药水瓶连通。
进一步地，预填充笔式注射器还包括笔帽；笔帽为一端开口的中空壳体，笔帽的内壁上设置有第二环形凸起；药瓶护筒的外壁上设置有卡设第二环形凸起的环形槽。
本发明提供的预填充笔式注射器，在使用时，使用者固定固定筒，顺时针转动记忆连筒一定圈数，由于第一单向齿与棘爪在顺时针方向上锁死，所以转动筒以及转动筒内的螺杆不动，记忆连筒相对螺杆延轴向移动一定距离，刻度调节完毕。在注射时，使用者逆时针转动转动筒，转动筒带动螺杆以及螺杆上的记忆连筒转动，由于固定筒不动，螺杆以及记忆连筒旋转，并相对固定筒沿相反轴向方向移动相同距离，同时螺杆推动活塞移动，完成一定剂量的注射。待下次使用时，使用者再次顺时针转动记忆连筒，记忆连筒再次相对螺杆移动一定距离。待药水使用完后，记忆连筒内的凸起与螺杆上的挡块抵接，挡块阻挡记忆连筒相对螺杆转动，也即，此时，使用者不能顺时针转动记忆连筒，从而告知使用者该药水已经使用完毕。
本发明提供的预填充笔式注射器，当药水使用完毕后，使用者不能顺时针转动记忆连筒调整刻度，从而使用者可得知注射笔内的药水已经使用完毕。
附图说明
为了更清楚地说明本发明具体实施方式或现有技术中的技术方案，下面将对具体实施方式或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图是本发明的一些实施方式，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本发明实施例提供的预填充笔式注射器的装配图；
图2为本发明实施例提供的预填充笔式注射器的零件结构示意图；
图3为本发明实施例提供的预填充笔式注射器中转动筒和固定筒配合的结构示意图；
图4为本发明实施例提供的预填充笔式注射器中固定筒的结构示意图；
图5为本发明实施例提供的预填充笔式注射器中转动筒的结构示意图；
图6为本发明实施例提供的预填充笔式注射器中螺杆的结构示意图；
图7为本发明实施例提供的预填充笔式注射器中转动筒和螺杆配合的结构示意图；
图8为本发明实施例提供的预填充笔式注射器中顶帽连筒、记忆连筒和螺杆的结构示意图；
图9为本发明实施例提供的预填充笔式注射器中刻度转筒和顶帽连筒的结构示意图；
图10为本发明实施例提供的预填充笔式注射器中单面单向齿轮的结构示意图；
图11为本发明实施例提供的预填充笔式注射器中双面单向齿轮的结构示意图；
图12为本发明实施例提供的预填充笔式注射器中观察筒的结构示意图；
图13为本发明实施例提供的预填充笔式注射器中外筒的结构示意图。
附图标记：
1-顶帽；          2-弹簧；          3-顶帽连筒；
4-螺杆；            5-记忆连筒；       6-单面单向齿轮；
7-双面单向齿轮；    8-刻度转筒；       9-观察筒；
10-外筒；           11-转动筒；        12-固定筒；
13-活塞；           14-药水瓶；        15-药瓶护筒；
16-笔帽；           17-转动凸起；      18-第一单向齿；
19-棘爪；           20-第一固定凸起；  21-滑动凸起；
22-滑槽；           23-第三凹槽；      24-第一内螺纹；
25-第一外螺纹；     26-环形转动部；    27-转动条；
28-腰形孔；         29-挡块；          30-卡设凸起；
31-缺口；           32-卡槽；          33-观察口；
41-凸起；           42-切面。
具体实施方式
下面将结合附图对本发明的技术方案进行清楚、完整地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
在本发明的描述中，需要说明的是，术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。此外，术语“第一”、“第二”、“第三”仅用于描述目的，而不能理解为指示或暗示相对重要性。
在本发明的描述中，需要说明的是，除非另有明确的规定和限定，术语“安装”、“相连”、“连接”应做广义理解，例如，可以是固定连接， 也可以是可拆卸连接，或一体地连接；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间接相连，可以是两个元件内部的连通。对于本领域的普通技术人员而言，可以具体情况理解上述术语在本发明中的具体含义。
图1为本发明实施例提供的预填充笔式注射器的结构示意图；图2为本发明实施例提供的预填充笔式注射器的零件结构示意图；图3为本发明实施例提供的预填充笔式注射器中转动筒和固定筒配合的结构示意图；图4为本发明实施例提供的预填充笔式注射器中固定筒的结构示意图；图5为本发明实施例提供的预填充笔式注射器中转动筒的结构示意图；图6为本发明实施例提供的预填充笔式注射器中螺杆的结构示意图；图7为本发明实施例提供的预填充笔式注射器中转动筒和螺杆配合的结构示意图。如图1-7所示，本实施例提供的预填充笔式注射器，包括：螺杆4、记忆连筒5、固定筒12以及转动筒11；转动筒11的一端端面上，以转动筒11的轴线为中心，均匀围设有多个第一单向齿18；转动筒11靠近第一单向齿18一端的开口为腰形孔28；记忆连筒5设置在转动筒11内，记忆连筒5的内壁上设置有与螺杆4的螺纹相配合的凸起41；固定筒12一端端面上设置有与第一单向齿18相配合的棘爪19，且固定筒12上设置有与螺杆4相配合的第一内螺纹24；螺杆4上，沿螺杆4延伸的方向，相对地设置有两个切面42，螺杆4的一端设置有活塞13，另一端的螺槽内设置有挡块29，挡块29用于阻挡记忆连筒5相对螺杆4转动。
其中，螺杆4的两个切面42与腰形孔28的平面平行，且螺杆4可在腰形孔28内轴向移动。
棘爪19的数量可以为一个，也可以为两个以上的多个。较佳地，棘爪19的数量为两个，两个棘爪19对称设置在固定筒12一端端面上。 两个棘爪19与第一单向齿18的配合，可使第一单向齿18在转动的过程中更加稳定。
本发明提供的预填充笔式注射器，在使用时，使用者固定固定筒12，顺时针转动记忆连筒5一定圈数，由于第一单向齿18与棘爪19在顺时针方向上锁死，所以转动筒11以及转动筒11内的螺杆4不动，记忆连筒5相对螺杆4延轴向移动一定距离，刻度调节完毕。在注射时，使用者逆时针转动转动筒11，由于第一单向齿18与棘爪19在逆时针方向上未锁死，转动筒11带动螺杆4以及螺杆4上的记忆连筒5转动，由于固定筒12不动，螺杆4以及记忆连筒5旋转，并相对固定筒12沿相反轴向方向移动相同距离，同时螺杆4推动活塞13移动，完成一定剂量的注射。待下次使用时，使用者再次顺时针转动记忆连筒5，记忆连筒5再次相对螺杆4移动一定距离。待药水使用完后，记忆连筒5内的凸起41与螺杆4上的挡块29抵接，挡块29阻挡记忆连筒5相对螺杆4转动，也即，此时，使用者不能顺时针转动记忆连筒5，从而告知使用者该药水已经使用完毕。
本发明提供的预填充笔式注射器，当药水使用完毕后，使用者不能顺时针转动记忆连筒5调整刻度，从而使用者可得知注射器内的药水已经使用完毕。
图8为本发明实施例提供的预填充笔式注射器中顶帽连筒、记忆连筒和螺杆的结构示意图；图9为本发明实施例提供的注射笔中刻度转筒和顶帽连筒的结构示意图；如图1-9所示，在上述实施例的基础上，进一步地，预填充笔式注射器还包括固定壳体、刻度转筒8和顶帽连筒3；固定筒12的外壁上设置有第一固定凸起20；固定壳体为两端开口的中空壳体，固定壳体的内壁上设置有第二内螺纹，另一端内壁上设置有与第一固定凸起20相配合的第一凹槽；刻度转筒8的外壁上设置有与第二内螺纹相配合的第一外螺纹25，刻度转筒8的内壁上设置有转动凸 起17；顶帽连筒3设置在刻度转筒8内，且顶帽连筒3的外壁上设置有与转动凸起17相卡合的第二凹槽；顶帽连筒3的内壁上，沿顶帽连筒3延伸的方向，设置有滑槽22；记忆连筒5远离固定筒的一端设置有与滑槽22相配合的滑动凸起21。
其中，第一固定凸起20的形状可以为多种，例如：方形、圆形或者环形等等。
第一固定凸起20和第一凹槽的数量可以为一个，也可以为两个以上的多个。
本实施例中，在使用时，使用者手握固定壳体，顺时针转动刻度转筒8，固定壳体和固定筒12不动，由于刻度转筒8与固定壳体有螺纹配合关系，刻度转筒8相对固定壳体旋转并轴向移动一定距离，同时，刻度转筒8带动顶帽连筒3旋转并沿轴向移动，顶帽连筒3带动记忆连筒5相对螺杆4旋转并沿轴向移动一定距离，刻度调节完毕。使用者逆时针转动转动筒11，完成注射。
本实施例中，通过设置固定壳体、刻度转筒8和顶帽连筒3，使用者转动刻度转筒8即可实现记忆连筒5相对螺杆4的转动，即通过固定壳体、刻度转筒8和顶帽连筒3的配合实现刻度的调节，方便使用者使用。同时，固定壳体可防止刻度转筒8和顶帽连筒3落入灰尘，从而可保持注射笔部件的清洁。
图10为本发明实施例提供的预填充笔式注射器中单面单向齿轮的结构示意图；图11为本发明实施例提供的预填充笔式注射器中双面单向齿轮的结构示意图，如图1-11所示，在上述实施例的基础上，进一步地，预填充笔式注射器还包括顶帽1、弹簧2、单面单向齿轮6和两面齿倾斜方向相互交叉的双面单向齿轮7；转动筒11的外壁上，延转动筒11延伸的方向，设置有转动条27；刻度转筒8靠近固定筒12一端的内壁上设置有环形凸台，环形凸台上，以刻度转筒8的轴线为中心， 均匀围设有多个第二单向齿；双面单向齿轮7套设在转动筒11上，其一面与单面单向齿轮6配合，另一面与第二单向齿配合；单面单向齿轮6的内壁上设置有与转动条27相配合的第三凹槽23，单面单向齿远离双面单向齿的一面与顶帽连筒3的一端抵接；顶帽连筒3另一端端面上设置有连接盘，连接盘远离顶帽连筒3的一面上设置有套筒，连接盘的周面上设置有与转动凸起17相配合的凹槽；顶帽1为一端开口的中空壳体，顶帽1的内端面上设置有圆柱体；圆柱体设置在套筒内；弹簧2套设在套筒外，其一端与连接盘抵接，另一端与顶帽1的内端面抵接。
其中，双面单向齿轮7为两端开口的中空壳体，其两端端面上，以双面单向齿轮7的轴线为中心，分别均匀围设有多个单向齿，且两端端面上的单向齿倾斜方向交叉。
单面单向齿轮6为两端开口的中空壳体，其一端端面上，以单面单向齿轮6的轴线为中心，均匀围设有多个单向齿。
本实施例中，在使用时，使用者手握固定壳体，顺时针转动刻度转筒8，刻度转筒8旋转并沿轴向方向移动，同时刻度转筒8带动顶帽连筒3、顶帽连筒3带动记忆连筒5旋转并沿轴向方向移动，由于第一单向齿18与双面单向齿轮7之间的齿处于未锁死状态，双面单向齿轮7与单面单向齿轮6之间的齿处于锁死状态，同时，单面单向齿轮6与转动筒11有转动条27和第三凹槽23的配合，因此，双面单向齿轮7与单面单向齿轮6同时沿轴向方向移动而无旋转，并同时推动顶帽连筒3轴向移动。当双面单向齿轮7与第一单向齿18之间出现跳齿时，弹簧2被压缩，双面单向齿轮7与第一单向齿18之间跳齿后，弹簧2伸展回复原状，从而使得使用者在旋转刻度转筒8时，弹簧2反复压缩和伸展。
在注射时，使用者向下按住顶帽1，使得顶帽连筒3、双面单向齿轮7和单面单向齿轮6无间隙，从而使得弹簧2无弹跳空间，第一单向 齿18与双面单向齿无法产生齿跳动。此时，使用者逆时针旋转刻度转筒8，刻度转筒8通过双面单向齿轮7带动单面单向齿轮6转动，单面单向齿轮6带动转动筒11转动，转动筒11带动螺杆4转动并沿相反轴向方向移动。同时，刻度转筒8带动顶帽连筒3转动并沿相反轴向方向移动，顶帽1连筒3带动记忆连筒5旋转并沿相反轴向方向移动。由于，此时螺杆4和记忆连筒5的角速度相同，因此，螺杆4和记忆连筒5同时旋转并沿相反轴线方向移动，螺杆4推动活塞13移动，完成注射。
本实施例中，在转动筒11上设置双面单向齿轮7和单面单向齿轮6，使用者转动刻度转筒8即可完成刻度的调节和药水的注射，操作方便。另外，双面单向齿轮7和第一单向齿18之间齿的跳动，可方便使用者在旋转刻度转筒8时控制转动的力度，方便刻度调节。
图12为本发明实施例提供的预填充笔式注射器中观察筒的结构示意图；图13为本发明实施例提供的预填充笔式注射器中外筒的结构示意图。如图1、图2、图12和图13所示，在上述实施例的基础上，进一步地，固定壳体包括外筒10和观察筒9；外筒10一端内壁上设置有卡槽32，另一端内壁上设置有第一凹槽，外筒10上设置有观察口33；观察筒9一端外壁上设置有与卡槽32相配合的卡设凸起30，观察筒9与观察口33相对应的位置上设置有缺口31，缺口31与观察口33连通，观察筒9内设置有第二内螺纹。
本实施例中，将固定壳体设置为外筒10和观察筒9，且在外筒10上设置观察口33，在观察筒9上设置缺口31，这样的设置方便使用者观察刻度转筒8移出的距离，即方便观察刻度数值。
如图9所示，在上述实施例的基础上，进一步地，刻度转筒8靠近顶帽1的一端设置有两端开口的环形转动部26，环形转动部26套设在顶帽1外，转动凸起17设置在环形转动部26的内壁上。
其中，可在环形转动部26的外壁上设置多个凸起，从而可使使用者手握环形转动部26转动时，使用者的手与环形转动部26之间的摩擦力增大，方便使用者转动。
本实施例中，在刻度转筒8上设置环形转动部26，使用者在使用时旋转环形转动部26即可转动刻度转筒8，方便使用者操作。
如图1和图2所示，在上述实施例的基础上，进一步地，顶帽1的外壁上设置有环形槽，环形转动部26的内壁上设置有第一环形凸起，第一环形凸起设置在环形槽内，且第一环形凸起与环形槽的侧壁之间具有间隙。
本实施例中，在第一单向齿18和双面单向齿发生齿的跳动时，顶帽连筒3沿轴向移动，环形槽相对第一环形凸起移动，弹簧2压缩。在第一单向齿18和双面单向齿发生齿的跳动后，环形槽相对第一环形凸起向相反方向移动，弹簧2伸展。
本实施例中，通过第一环形凸起41和环形槽的配合，从而限定顶帽1连筒3相对刻度转筒8的相对位移，结构简单，操作方便。
如图1和图2所示，在上述实施例的基础上，进一步地，预填充笔式注射器还包括药水瓶14和针头；药水瓶14一端开口，另一端插设针头，且针头与药水瓶14连通；活塞13设置在药水瓶14内，且活塞13的周面与药水瓶14的内壁抵接。
本实施例中，使用者顺时针转动刻度转筒8调节刻度，再按下顶帽1，逆时针转动刻度转筒8，活塞13移动并推动药水通过针头注射至人体。
本实施例中，药水瓶14和针头配合完成注射，结构简单，方便加工制造。
如图1和图2所示，在上述实施例的基础上，进一步地，预填充笔式注射器还包括药瓶护筒15；外筒10靠近固定筒12的一端内壁上设 置有第二固定凸起；药瓶护筒15两端开口，药瓶护筒15套设在药水瓶14外，其靠近固定筒12的一端外壁上设置有与第二固定凸起相卡合固定的第四凹槽。
本实施例中，在药水瓶14外设置药瓶护筒15，药瓶护筒15可对药水瓶14起到保护作用，从而避免药水瓶14受外力碰撞而破损，进而延长注射笔的使用寿命。
如图1和图2所示，在上述实施例的基础上，进一步地，药瓶护筒15远离固定筒12一端外壁上设置有第二外螺纹；针头包括针本体和旋转筒；旋转筒一端开口，其内壁设置有与第二外螺纹相配合的第三内螺纹；针本体一端插设在旋转筒封闭端上，且与药水瓶14连通。
本实施例中，通过旋转筒与药瓶护筒15之间的螺纹连接实现两者的可拆卸，方便使用者安装针头。
如图1和图2所示，在上述实施例的基础上，进一步地，预填充笔式注射器还包括笔帽16；笔帽16为一端开口的中空壳体，笔帽16的内壁上设置有第二环形凸起；药瓶护筒的外壁上设置有卡设第二环形凸起的环形槽。
本实施例中，在使用时，使用者将笔帽16从药瓶护筒上拔出，顺时针转动刻度转筒8调节刻度，按下顶帽1，逆时针转动刻度转筒8完成注射。
本实施例中，使用者在不使用注射器时，将笔帽16套设在药瓶护筒外，可避免针头落入灰尘等杂质，保证了注射器使用时的清洁性。
最后应说明的是：以上各实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述各实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分或者全部技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各实施例技术 方案的范围。

Claims (10)

  1. 一种预填充笔式注射器，其特征在于，所述预填充笔式注射器包括：螺杆、记忆连筒、固定筒以及转动筒；
    所述转动筒的一端端面上，以所述转动筒的轴线为中心，均匀围设有多个第一单向齿；所述转动筒靠近所述第一单向齿一端的开口为腰形孔；所述记忆连筒设置在所述转动筒内，所述记忆连筒的内壁上设置有与所述螺杆的螺纹相配合的凸起；所述固定筒一端端面上设置有与所述第一单向齿相配合的棘爪，且所述固定筒上设置有与所述螺杆相配合的第一内螺纹；
    所述螺杆上，沿所述螺杆延伸的方向，相对地设置有两个切面，所述螺杆的一端设置有活塞，另一端的螺槽内设置有挡块，所述挡块用于阻挡所述记忆连筒相对所述螺杆转动。
  2. 根据权利要求1所述的预填充笔式注射器，其特征在于，所述预填充笔式注射器还包括固定壳体、刻度转筒和顶帽连筒；
    所述固定筒的外壁上设置有第一固定凸起；所述固定壳体为两端开口的中空壳体，所述固定壳体的内壁上设置有第二内螺纹，另一端内壁上设置有与所述第一固定凸起相配合的第一凹槽；所述刻度转筒的外壁上设置有与所述第二内螺纹相配合的第一外螺纹，所述刻度转筒的内壁上设置有转动凸起；所述顶帽连筒设置在所述刻度转筒内，且所述顶帽连筒的外壁上设置有与所述转动凸起相卡合的第二凹槽；所述顶帽连筒的内壁上，沿所述顶帽连筒延伸的方向，设置有滑槽；所述记忆连筒远离所述固定筒的一端设置有与所述滑槽相配合的滑动凸起。
  3. 根据权利要求2所述的预填充笔式注射器，其特征在于，所述预填充笔式注射器还包括顶帽、弹簧、单面单向齿轮和两面齿倾斜方向相互交叉的双面单向齿轮；
    所述转动筒的外壁上，延所述转动筒延伸的方向，设置有转动条；所述刻度转筒靠近所述固定筒一端的内壁上设置有环形凸台，所述环形凸台上，以所述刻度转筒的轴线为中心，均匀围设有多个第二单向齿；所述双面单向齿轮套设在所述转动筒上，其一面与所述单面单向齿轮配合，另一面与所述第二单向齿配合；所述单面单向齿轮的内壁上设置有与所述转动条相配合的第三凹槽，所述单面单向齿远离所述双面单向齿的一面与所述顶帽连筒的一端抵接；所述顶帽连筒另一端端面上设置有连接盘，所述连接盘远离所述顶帽连筒的一面上设置有套筒，所述连接盘的周面上设置有与所述转动凸起相配合的凹槽；
    所述顶帽为一端开口的中空壳体，所述顶帽的内端面上设置有圆柱体；所述圆柱体设置在所述套筒内；所述弹簧套设在所述套筒外，其一端与所述连接盘抵接，另一端与所述顶帽的内端面抵接。
  4. 根据权利要求3所述的预填充笔式注射器，其特征在于，所述固定壳体包括外筒和观察筒；
    所述外筒一端内壁上设置有卡槽，另一端内壁上设置有所述第一凹槽，所述外筒上设置有观察口；所述观察筒一端外壁上设置有与所述卡槽相配合的卡设凸起，所述观察筒与所述观察口相对应的位置上设置有缺口，所述缺口与所述观察口连通，所述观察筒内设置有所述第二内螺纹。
  5. 根据权利要求4所述的预填充笔式注射器，其特征在于，所述刻度转筒靠近所述顶帽的一端设置有两端开口的环形转动部，所述环形转动部套设在所述顶帽外，所述转动凸起设置在所述环形转动部的内壁上。
  6. 根据权利要求5所述的预填充笔式注射器，其特征在于，所述顶帽的外壁上设置有环形槽，所述环形转动部的内壁上设置有第一环形 凸起，所述第一环形凸起设置在所述环形槽内，且所述第一环形凸起与所述环形槽的侧壁之间具有间隙。
  7. 根据权利要求1所述的预填充笔式注射器，其特征在于，所述预填充笔式注射器还包括药水瓶和针头；
    所述药水瓶一端开口，另一端插设所述针头，且所述针头与所述药水瓶连通；所述活塞设置在所述药水瓶内，且所述活塞的周面与所述药水瓶的内壁抵接。
  8. 根据权利要求7所述的预填充笔式注射器，其特征在于，所述预填充笔式注射器还包括药瓶护筒；
    所述外筒靠近所述固定筒的一端内壁上设置有第二固定凸起；所述药瓶护筒两端开口，所述药瓶护筒套设在所述药水瓶外，其靠近所述固定筒的一端外壁上设置有与所述第二固定凸起相卡合固定的第四凹槽。
  9. 根据权利要求8所述的预填充笔式注射器，其特征在于，所述药瓶护筒远离所述固定筒一端外壁上设置有第二外螺纹；
    所述针头包括针本体和旋转筒；所述旋转筒一端开口，其内壁设置有与所述第二外螺纹相配合的第三内螺纹；所述针本体一端插设在所述旋转筒封闭端上，且与所述药水瓶连通。
  10. 根据权利要求9所述的预填充笔式注射器，其特征在于，所述预填充笔式注射器还包括笔帽；
    所述笔帽为一端开口的中空壳体，所述笔帽的内壁上设置有第二环形凸起；所述药瓶护筒的外壁上设置有卡设所述第二环形凸起的环形槽。
PCT/CN2017/081254 2016-04-21 2017-04-20 预填充笔式注射器 Ceased WO2017181967A1 (zh)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109107003A (zh) * 2018-09-13 2019-01-01 张露 一种新型注射笔
CN116650763A (zh) * 2023-06-02 2023-08-29 苏州赛卫生物科技有限公司 自动注射胰岛素笔

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
JP7017512B2 (ja) 2015-10-09 2022-02-08 ウェスト ファーマ サービシーズ イスラエル リミテッド 充填済流体容器の屈曲流体路型付属物
US11311674B2 (en) 2016-01-21 2022-04-26 West Pharma. Services IL, Ltd. Medicament delivery device comprising a visual indicator
CN105749383B (zh) * 2016-04-21 2017-03-08 北京甘甘科技有限公司 预填充笔式注射器
CN106215288A (zh) * 2016-09-28 2016-12-14 江苏德尔福医疗器械有限公司 排气可调的定量注射器
JP7313795B2 (ja) * 2016-10-10 2023-07-25 ウエスト・ファーマ．サービシーズ・イスラエル，リミテッド 角度付注射器パッチ式注入器
CN106620963B (zh) * 2016-11-01 2022-11-11 昆山翰尔西医疗器械有限公司 一种推送装置
CN107050575B (zh) * 2017-04-24 2023-02-24 无锡市馨亿生物医疗科技有限公司 一种可重复使用的笔式注射器
CN107274637B (zh) * 2017-07-14 2023-01-31 河南驰诚电气股份有限公司 旋转配合装置及警报器
US11369748B2 (en) * 2017-12-04 2022-06-28 Novo Nordisk A/S Drug injection device with deflectable transducers
US12465695B2 (en) 2018-08-15 2025-11-11 Sanofi Data collection apparatus for attachment to an injection device
CN111084918A (zh) * 2018-10-24 2020-05-01 群康生技股份有限公司 具有注射剂量调整功能的注射器
CN109395205B (zh) * 2018-11-12 2024-07-16 江苏万海医疗器械有限公司 注射装置及注射装置组件
CN110141727B (zh) * 2019-05-06 2024-07-30 甘甘医疗科技江苏有限公司 药物输送装置
CN110215573B (zh) * 2019-06-06 2025-02-14 甘甘医疗科技江苏有限公司 单向转动机构及具有其的注射器
CN113750323B (zh) * 2020-06-03 2025-02-11 苏州天合云朵医疗科技有限公司 一种可循环使用精准注射推送装置
CN114129824B (zh) * 2020-09-03 2026-01-02 甘甘医疗科技江苏有限公司 药物输送装置
CN112156278A (zh) * 2020-10-14 2021-01-01 上海优米泰医疗科技有限公司 一种带有记忆功能的注射装置
CN112999089B (zh) * 2021-03-10 2023-05-30 青岛市中医医院(青岛市海慈医院、青岛市康复医学研究所) 一种儿科用药物捣碎方法
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CN113332537A (zh) * 2021-06-04 2021-09-03 常熟康信医疗器械有限公司 一种便携式智能注射器组件
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CN117224781B (zh) * 2023-09-11 2024-09-10 上海倍莱弗科技有限公司 可设定与回调剂量的给药装置

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829381A (zh) * 2010-04-07 2010-09-15 邓源基 一次性可调计量胰岛素注射笔
CN104321096A (zh) * 2012-03-30 2015-01-28 特克法马许可公司 带有剂量显示器和弹簧驱动器的注射装置
WO2015032780A1 (en) * 2013-09-03 2015-03-12 Sanofi Pen-type drug injection device with dose setting and re-setting mechanism
WO2016055623A1 (en) * 2014-10-09 2016-04-14 Sanofi Drive sleeve, drug delivery device and method for assembling a drug delivery device
CN105749383A (zh) * 2016-04-21 2016-07-13 北京甘甘科技有限公司 预填充笔式注射器
CN205759066U (zh) * 2016-04-21 2016-12-07 北京甘甘科技有限公司 预填充笔式注射器

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1545663B1 (en) 2002-10-01 2006-08-30 Becton Dickinson and Company Medication delivery pen
EP1663354A1 (en) * 2003-09-03 2006-06-07 Novo Nordisk A/S Threaded rod and nut assembly
PL1843809T3 (pl) * 2005-01-21 2017-09-29 Novo Nordisk A/S Automatyczne urządzenie wstrzykujące z górnym mechanizmem wyzwalania
WO2007060156A1 (en) * 2005-11-22 2007-05-31 Novo Nordisk A/S System of different shaped injection devices
WO2013137893A1 (en) * 2012-03-15 2013-09-19 Becton, Dickinson And Company Multiple use disposable injection pen
CN102716529B (zh) * 2012-06-29 2014-02-19 北京甘甘科技有限公司 笔式注射器
EP2829292B1 (de) * 2013-07-22 2017-11-01 TecPharma Licensing AG Antriebs- und Dosiervorrichtung mit einem Begrenzungselement zur Verhinderung der Einstellung einer höheren Dosis als verfügbar

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829381A (zh) * 2010-04-07 2010-09-15 邓源基 一次性可调计量胰岛素注射笔
CN104321096A (zh) * 2012-03-30 2015-01-28 特克法马许可公司 带有剂量显示器和弹簧驱动器的注射装置
WO2015032780A1 (en) * 2013-09-03 2015-03-12 Sanofi Pen-type drug injection device with dose setting and re-setting mechanism
WO2016055623A1 (en) * 2014-10-09 2016-04-14 Sanofi Drive sleeve, drug delivery device and method for assembling a drug delivery device
CN105749383A (zh) * 2016-04-21 2016-07-13 北京甘甘科技有限公司 预填充笔式注射器
CN205759066U (zh) * 2016-04-21 2016-12-07 北京甘甘科技有限公司 预填充笔式注射器

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3446733A4 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109107003A (zh) * 2018-09-13 2019-01-01 张露 一种新型注射笔
CN109107003B (zh) * 2018-09-13 2024-01-26 深圳惠迈智能科技有限公司 一种新型注射笔
CN116650763A (zh) * 2023-06-02 2023-08-29 苏州赛卫生物科技有限公司 自动注射胰岛素笔

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