WO2019128773A1 - 用于分支血管的支架 - Google Patents

用于分支血管的支架 Download PDF

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Publication number
WO2019128773A1
WO2019128773A1 PCT/CN2018/121720 CN2018121720W WO2019128773A1 WO 2019128773 A1 WO2019128773 A1 WO 2019128773A1 CN 2018121720 W CN2018121720 W CN 2018121720W WO 2019128773 A1 WO2019128773 A1 WO 2019128773A1
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WO
WIPO (PCT)
Prior art keywords
developing
stent
developing portion
bracket
blood vessels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2018/121720
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English (en)
French (fr)
Inventor
肖本好
方毅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lifetech Scientific Shenzhen Co Ltd
Original Assignee
Lifetech Scientific Shenzhen Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifetech Scientific Shenzhen Co Ltd filed Critical Lifetech Scientific Shenzhen Co Ltd
Priority to PL18893638.9T priority Critical patent/PL3733121T3/pl
Priority to ES18893638T priority patent/ES2924079T3/es
Priority to EP18893638.9A priority patent/EP3733121B1/en
Publication of WO2019128773A1 publication Critical patent/WO2019128773A1/zh
Priority to US16/913,764 priority patent/US11529248B2/en
Anticipated expiration legal-status Critical
Priority to US17/990,913 priority patent/US12156823B2/en
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/852—Two or more distinct overlapping stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/856—Single tubular stent with a side portal passage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91575—Adjacent bands being connected to each other connected peak to trough
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers

Definitions

  • the present invention relates to the field of medical devices, and more particularly to a stent for branching blood vessels.
  • vascular stents are placed in the lesions to support the vessels in the stenosis and occlusion, reduce the elastic retraction and reshape the blood vessels, and maintain the blood flow in the lumen. the goal of.
  • treatment of the vascular lesion with the main stent can block the blood flow of the branch vessel, causing occlusion of the branch vessel or insufficient blood supply.
  • the diseased blood vessel 10 includes a main blood vessel 110 and a branch blood vessel 120.
  • the branch blood vessel 120 extends from the main blood vessel 110, and the branch blood vessel 120 is connected to the main blood vessel 110 to form an intersection 111, and the lesion 112 is formed on the blood vessel wall of the main blood vessel 110 near the intersection 111.
  • a common method is to insert the main body bracket 200 in the main blood vessel 110 when the diseased blood vessel 10 is reconstructed, and to open the window in the main body bracket 200 at the intersection 110. Then, the branch guide wire approach is used to introduce a stent for the branch vessel to complete the reconstruction of the branch vessel.
  • the relative position of the stent for branching and the body stent of the in-situ fenestration cannot be expressed, and the position of the stent for branching blood vessels entering the main stent is uncertain, when the stent for branching blood vessels enters the main stent When the inside is too long, it may cause blockage of blood flow inside the main body stent.
  • the anchoring property of the stent for branching blood vessels in the main body stent may be deteriorated, and The distal end of the stent for branching blood vessels may also cause blockage of the distal branch port; in addition, the current way of reconstructing the branch vessel is not recognized when the branch vessel is distorted or knotted.
  • a bracket for branching a blood vessel comprising: a bracket body and a first developing member, the bracket body having a first end and a second end opposite to the first end, the first developing member being located at the first Between the end and the second end and adjacent to the first end, the first developing member comprises a first developing portion and a second developing portion;
  • the first developing portion extends in a first direction
  • the second developing portion extends in a second direction
  • the first direction obliquely intersects the second direction
  • the first developing portion and the second portion The length of the developing portion in the axial direction of the bracket body is not less than 0.5 mm;
  • a distance between the intersection of the first developing portion and the second developing portion on a plane perpendicular to the axis direction of the bracket body is perpendicular to the bracket body from the first developing portion and the second developing portion a position where a distance between intersections on a plane in the axial direction is the smallest to an end of the first developing portion or the second developing portion away from the first end, and the first developing portion and the first portion
  • the minimum distance between the intersections of the two developing portions on a plane perpendicular to the axial direction of the stent body is not more than 2 mm.
  • a distance between an intersection of the first developing portion and the second developing portion near the first end in a plane perpendicular to the axis direction of the bracket body is the smallest.
  • the bracket body includes a bare bracket and a coating covering the bare bracket, and the first developing portion and the second developing portion are both disposed on the bare bracket.
  • the bare bracket includes a plurality of axially arranged coils, the coil includes a plurality of alternating peaks and troughs, and waves passing between the peaks and the valleys
  • the rods are connected, the first developing portion is disposed on the wave rod, and the second developing portion is disposed on the adjacent wave rods on the same wave circle as the first developing portion.
  • the length of the first developing portion and the second developing portion is 1/2 to 2/3 of the length of the pole in which the beam is located.
  • a distance between the first developing portion and the second developing portion at a minimum distance between intersections on a plane perpendicular to the axis direction of the bracket body is 5 mm from the first end. ⁇ 10mm.
  • the bracket body includes a proximal end portion, a connecting portion and a distal end portion that are sequentially connected, and the first end portion of the proximal end portion away from the connecting portion forms the first end, the distal end portion Forming the second end away from an end of the connecting portion;
  • a cross-sectional area of the connecting portion near an end of the proximal end portion is less than or equal to a cross-sectional area of an end of the connecting portion near the distal end portion, and the connecting portion is adjacent to an end of the proximal end portion
  • a line connecting the connecting portion to an end of the distal end portion forms an angle of 0 to 30° with the axial direction, and the first developing member is located at the proximal end portion.
  • the second developing member and the third developing member are further included, the second developing member is disposed at the first end, and the third developing member is disposed at the second end.
  • the method further includes a skirt bracket sleeved on the bracket body, the skirt bracket is coupled to the bracket body and extends toward the first end, the first developing portion and the An end of the second developing portion away from the first end is located at a joint of the skirt bracket and the bracket body.
  • the skirt bracket includes a flexible section and a folded section connected to the flexible section, the flexible section is coupled to the bracket body, and the first developing portion or the second developing portion is away from a distance from one end of the first end to a position where the distance between the intersection of the first developing portion and the second developing portion on a plane perpendicular to the axis direction of the bracket body is the same as the contour of the flexible segment length.
  • the above-described stent for branching blood vessels can conveniently observe the middle portion of the stent for branching blood vessels by providing a first developing member between the first end and the second end, and can be present in the release of the stent for branching blood vessels.
  • the distortion and the folding are recognized, and the distance between the intersection of the first developing portion and the second developing portion on a plane perpendicular to the axis direction of the bracket body is from the first developing portion and the second developing portion in a direction perpendicular to the axis of the bracket body
  • the position where the distance between the intersections on the plane is the smallest is gradually increased to the end of the first developing portion or the second developing portion away from the first end, and when the operation is performed, the development of the wire in the main body bracket can be avoided for the branch blood vessel
  • the occlusion and confusion of the developing member of the stent is advantageous for observing and predicting the relative position of the stent for the branch vessel in the body stent when the stent for the branch vessel is
  • FIG. 1 is a schematic structural view of a diseased blood vessel according to an embodiment
  • FIG. 2 is a schematic structural view of the diseased blood vessel shown in FIG. 1 placed in a main body bracket;
  • FIG. 3 is a schematic structural view of a stent for branching blood vessels according to an embodiment
  • FIG. 4 is a schematic structural view of the stent for branching blood vessels shown in FIG. 3 placed on the main body bracket;
  • FIG. 5 is a schematic structural view of a stent for branching blood vessels in a natural state according to another embodiment
  • Figure 6 is a schematic view showing the structure of the stent for branching blood vessels shown in Figure 5 when sheathing;
  • Figure 7 is a schematic view showing the structure of the stent for branching blood vessels shown in Figure 5 when sheathing is completed;
  • Figure 8 is a schematic view showing the structure of the stent for branching blood vessels shown in Figure 5 placed on the main body bracket;
  • Figure 9 is an enlarged schematic view of the portion of the circle A of Figure 8.
  • the stent 300 for branching blood vessels of the embodiment includes a bracket body 310 and a developing assembly 320.
  • the developing assembly 320 is disposed on the bracket body 310.
  • the bracket body 310 has a first end 316 and is opposite to the first end. The second end 317.
  • the stent body 310 includes a bare stent and a coating 315 covering the bare stent.
  • the bare bracket includes a plurality of coils 312 arranged in the axial direction.
  • the wave circle 312 includes a plurality of peaks and troughs alternately arranged, and adjacent peaks and troughs are connected by a wave rod.
  • the angle formed by the extension of the adjacent two poles is from 30° to 120°.
  • the stent body 310 is formed with a proximal portion 3101, a connecting portion 3102, and a distal portion 3103 that are sequentially connected.
  • the first end 316 is formed at one end of the proximal end portion 3101 away from the connecting portion 3102, and the second end 317 is formed at one end of the distal end portion 3103 away from the connecting portion 3102.
  • the film of the first end 316 forms a petal-shaped structure to facilitate blood flow from the first end; the film of the second end 317 is of a flush structure.
  • the cross-sectional area of the proximal portion 3101 is less than the cross-sectional area of the distal portion 3103.
  • the cross-sectional area of the connecting portion 3102 near the end of the proximal portion 3101 is less than or equal to the cross-sectional area of the end of the connecting portion 3102 near the distal end portion 3103, and the connecting portion 3102 is near the end of the proximal portion 3101 and the connecting portion 3102 is near the distal end.
  • the line connecting one end of the portion 3103 forms an angle of 0 to 30° with respect to the axial direction.
  • a line connecting the one end of the connecting portion 3102 near the proximal end portion 3101 and the end portion of the connecting portion 3102 near the distal end portion 3103 forms an angle of 15° to 25° with respect to the axial direction.
  • the above structure allows the main body bracket 310 to form a tapered structure, which can increase the anchoring force of the distal end portion 3103 while suppressing the aortic pulsation from being transmitted to the distal end portion 3103 of the stent for branching blood vessels.
  • proximal portion 3101, the connecting portion 3102, and the distal portion 3103 are only for convenience of explanation, and do not mean that the bracket body 310 is separated and disconnected at the connection boundary, and the bracket body 310 may be a uniform integrated structure.
  • the developing assembly 320 includes a first developing member 321, a second developing member 322, and a third developing member 323.
  • the first developing member 321 is located between the first end 316 and the second end 317 and adjacent to the first end 316. Specifically, the first developing member 321 is located at the proximal end portion 3101.
  • the second developing member 322 is disposed at the first end 316, and the third developing member 323 is disposed at the second end 317.
  • the second developing member 322 is used to characterize the beginning end of the stent 300 for branching blood vessels.
  • the third developing member 323 is used to characterize the terminating end of the stent 300 for branching blood vessels.
  • the development assembly 320 is disposed on a bare bracket of the stent body 310. It will be appreciated that in other embodiments, at least one of the developing assemblies 320 may also be formed on the film 315.
  • the first developing member 321 includes a first developing portion 3211 and a second developing portion 3212.
  • the first developing portion 3211 extends in the first direction
  • the second developing portion 3212 extends in the second direction.
  • the first developing portion 3211 and the second developing portion 3212 have a length in the axial direction of the bracket body 310 of not less than 0.5 mm.
  • the distance between the intersection of the first developing portion 3211 and the second developing portion 3212 on a plane perpendicular to the axial direction of the holder body 310 is from a plane perpendicular to the axis direction of the holder body 310 from the first developing portion 3211 and the second developing portion 3212.
  • the minimum distance between the intersections on the plane is no more than 2 mm.
  • the distance between the first developing portion 3211 and the second developing portion 3212 near the first end 316 is the smallest between the intersections on the plane perpendicular to the axial direction of the bracket body 310.
  • the first developing portion 3211 and the second developing portion 3212 are symmetrical about the axis of the bracket body 310.
  • first developing portion 3211 and the second developing portion 3212 may also be located at the first developing portion 3211 and/or the second developing portion at a minimum distance between the intersections on the plane perpendicular to the axial direction of the bracket body 310. The middle of the portion 3212.
  • the first developing portion 3211 and the second developing portion 3212 are both disposed on the bare bracket.
  • the first developing portion 3211 is disposed on one of the wave rods 312, and the second developing portion 3212 is disposed on the wave rod 312 on the wave rod adjacent to the first developing portion 3211.
  • the first developing unit 3211 and the second developing unit 3212 are respectively formed by winding a developing material (for example, a twisted wire or the like) on a corresponding wave rod.
  • the lengths of the first developing unit 3211 and the second developing unit 3212 are 1/2 to 2/3 of the length of the pole in which it is placed to facilitate sheathing.
  • the first developing unit 3211 and the second developing unit 3212 both extend from the position close to the peak to the trough, and the peaks of the first developing unit 3211 and the second developing unit 3212 are not connected. That is, the first developing portion 3211 and the second developing portion 3212 form a " ⁇ /" type structure with a gap between the end points.
  • the lengths of the first developing unit 3211 and the second developing unit 3212 are both 2 to 4 mm.
  • first developing portion 3211 and the second developing portion 3212 may also be connected to each other to form a V-shaped structure.
  • the distance between the first developing portion 3211 and the second developing portion 3212 at the minimum distance between the intersections on the plane perpendicular to the axial direction of the bracket body 310 is 5 to 10 mm from the first end, which can be used for One end of the stent 300 for branching blood vessels is 5 to 10 mm beyond the length of the main body bracket 200, so that the stent 300 for branching blood vessels can be prevented from falling off from the main body stent 200, and the stent 300 for branching blood vessels can also be reduced for the main body.
  • the effect of blood flow in the stent 200 is 5 to 10 mm from the first end, which can be used for One end of the stent 300 for branching blood vessels is 5 to 10 mm beyond the length of the main body bracket 200, so that the stent 300 for branching blood vessels can be prevented from falling off from the main body stent 200, and the stent 300 for branching blood vessels can also be reduced for the main body.
  • the effect of blood flow in the stent 200 is 5
  • the second developing member 322 and the third developing member 323 are also disposed on the wave rod of the coil.
  • the second developing member 322 is disposed on the first wave ring adjacent to the first end 316
  • the third developing member 323 is disposed on the first wave ring adjacent to the second end 317.
  • Both the second developing member 322 and the third developing member 323 can be formed by winding a developing material on the wave rod.
  • the second developing member 322 and the third developing member 323 are both of an I-type structure.
  • the lengths of the second developing member 322 and the third developing member 323 may be 1/2 to 2/3 of the length of the rod. In the present embodiment, the lengths of the second developing member 322 and the third developing member 323 are both 2 to 4 mm.
  • the second developing member 322 and the third developing member 323 may have other structures, and the number thereof may be plural.
  • the main body stent 200 is first completely released at the lesion, and then the in-situ window is opened at the intersection 111 of the main body stent 200 at the branch blood vessel.
  • the instrument is reamed to a predetermined aperture; then, along the branch guidewire, the stent 300 for the branch vessel is delivered from the branch vessel using a sheath.
  • the first end 316 is a front end for movement of the stent 300 for branching blood vessels, and the stent 300 for branching blood vessels is placed up to the first developing portion 3211 or the second developing portion 3212
  • the initial positioning of the insertion is completed; then, the stent 300 for branching blood vessels is released from the sheath tube, and the first developing portion 3211 or the second developing portion 3212 is away from the first portion.
  • One end 316 stops releasing when it is just released from the sheath tube; then the locking device of the sheath tube is locked, and the sheath tube and the stent 300 for branching blood vessels are moved in the branch vessel to move toward the end of the branch vessel away from the main blood vessel, moving
  • the first developing portion 3211 and the second developing portion 3212 are at the minimum position of the intersection distance on the plane perpendicular to the axial direction of the stent body 310, just when they are flush with the mouth wall of the intersection 111, the dragging is stopped and the branching blood vessel is used.
  • the stent 300 is completely released from the sheath to achieve reconstruction of the branch vessel.
  • the above-described stent 300 for branching blood vessels can conveniently observe the middle portion of the stent 300 for branching blood vessels by providing the first developing member 321 between the first end 316 and the second end 317, and can be used for branching blood vessels.
  • the stent 300 is identified by the distortion and folding that occurs during the release, and the length of the stent 300 for branching the blood vessel into the body stent 200 is also positioned, and the first developing portion 3211 and the second developing portion 3212 are perpendicular to the stent body 310.
  • the distance between the intersections on the plane in the axial direction is from the position where the distance between the intersection of the first developing portion 3211 and the second developing portion 3212 on the plane perpendicular to the axis direction of the stent body is the smallest to the first developing portion 3211 or the second
  • the one end of the developing portion 3212 away from the first end is gradually increased, and when the first developing portion 3211 and the second developing portion 3212 are moved out from the inside of the main body bracket 200 during the operation, the development of the wire in the main body bracket 200 can be avoided.
  • the occlusion and confusion of the developing member of the stent 300 for branching blood vessels, and then passing through the gradual first developing member 321 is advantageous for observing and predicting when the stent 300 for branching blood vessels is dragged.
  • the stent 400 for branching blood vessels of another embodiment includes a stent body 410, a developing member 420, and a skirt bracket 430.
  • the structure of the bracket body 410 and the developing member 420 is substantially the same as that in the previous embodiment, and details are not described herein again.
  • the skirt bracket 430 is sleeved on the outer side of the bracket body 410, and one end of the skirt bracket 430 is connected to the bracket body 410.
  • the other end of the skirt bracket 430 forms an open end, and the open end faces the first end. End 416.
  • the skirt bracket 430 includes a flexible section 431 and a folded section 432 that is coupled to the flexible section 431.
  • the flexible section 431 is coupled to the bracket body 410, and the flexible section 431 is coupled to the bracket body 410 by a connecting strap 434 for connection and support of the bracket body 410 and the flexible section 431, and the strap 434 can be stitched, wound, Formed by cutting or laminating.
  • an end of the first developing portion 4211 and the second developing portion 4212 away from the first end 416 is located at a joint of the skirt bracket 430 and the bracket body 410 , that is, the first developing portion 4211 and the second developing portion 4212 are away from the first portion.
  • One end of one end 416 is flush with the connecting strip 434.
  • the folded section 432 is rotatably coupled to the end of the flexible section 431 that is remote from the strap 434 such that the folded section 432 can be folded or folded.
  • the distance between the end of the first developing portion 4211 or the second developing portion 4212 away from the first end 416 to the intersection of the first developing portion 4211 and the second developing portion 4212 on a plane perpendicular to the axial direction of the bracket body 410 is the smallest.
  • the distance between the positions is equal to the length of the outline of the flexible section 431, that is, after the sheath is inserted, the first developing portion 4211 and the second developing portion 4212 intersect at a plane perpendicular to the axial direction of the stent body 410.
  • the position where the distance between the distances is the smallest is flush with the end of the flexible section 431 away from the bracket body 410 so as to indicate the starting position of the flexible section 431 by the first developing portion 4211 and the second developing portion 4212.
  • the flexible segment 431 extends away from the connecting strip 434 toward the first end 416 to abut the bracket body 410, the flexible segment 431 is adjacent to the end of the first end 416 and the first developing portion 4211 or the second.
  • the developing portion 4212 is flush with one end near the first end 416.
  • the diameter of the folded section 432 away from the end of the flexible section 431 ie, the end of the folded section 432 away from the flexible section 431 is perpendicular to the plane of the bracket body 410.
  • the distance of the projection on the upper side is 1.5 to 3 times the diameter of the stent body 410 at the position.
  • the diameter of the skirt bracket 430 is larger than the diameter of the bracket body 410 at the location, and such a design can effectively reduce the risk of endoleak caused by the cooperation between the brackets.
  • the length of the folded section 432 is less than the length of the flexible section 431.
  • the flexible section 431 is unfolded, and the folding section 432 is also turned away from the stent body 410 so that the skirt bracket 430 is folded.
  • the second end 417 of the stent body 410 first enters the sheath tube until the connecting strip 434 enters the sheath tube, and the flexible segment 431 is pushed under the inner wall of the sheath tube to It is attached to the bracket body 410, and at this time, the folding section 432 is still in an unfolded state.
  • the inner wall of the sheath pushes the folding section 432 to be folded to fit the main body bracket 410 to achieve the state shown in Fig. 7 to complete the sheathing process of the stent for branching blood vessels.
  • the main body stent 200 when performing the blood vessel reconstruction using the above-described stent 400 for branching blood vessels, the main body stent 200 is first completely released at the lesion, and then the body stent 200 is located at the intersection of the branch blood vessels.
  • the in-situ fenestration device is reamed to a predetermined aperture at the port 111; then, along the branch guidewire approach, the stent 400 for branching blood vessels is fed from the branch vessel using a sheath.
  • the first end 416 is a front end for moving the stent 400 for branching blood vessels, and the stent 400 for branching blood vessels is placed to the first developing portion 4211 and the second developing portion 4212.
  • the initial positioning of the insertion is completed after fully entering the main body bracket 200; then the stent 400 for branching blood vessels is released from the sheath tube until the first developing portion 4211 or the second developing portion 4212 is released from the first end 416.

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Abstract

一种用于分支血管的支架（300），包括支架本体（310）及第一显影件（321），第一显影件（321）包括第一显影部（3211）及第二显影部（3212）；第一显影部（3211）及第二显影部（3212）在支架本体（310）轴线方向上的长度均不小于0.5mm；第一显影部（3211）与第二显影部（3212）在垂直于支架本体（310）轴线方向的平面上的交点之间的距离从第一显影部（3211）与第二显影部（3212）在垂直于支架本体（310）轴线方向的平面上的交点之间距离最小的位置到第一显影部（3211）或第二显影部（3212）远离第一端（316）的一端逐渐增大，第一显影部（3211）与第二显影部（3212）在垂直于支架本体（310）轴线方向的平面上交点之间的最小距离不大于2mm。用于分支血管的支架（300）能够对用于分支血管的支架（300）的位置进行准确定位，且能够对用于分支血管的支架（300）的扭曲和打结进行识别。

Description

用于分支血管的支架 技术领域
本发明涉及医疗器械领域，特别是涉及用于分支血管的支架。
背景技术
在血管病变发生闭塞时，常常在管腔球囊扩张成形的基础上，在病变段置入血管支架以达到支撑狭窄闭塞段血管，减少血管弹性回缩及再塑形，保持管腔血流通畅的目的。然而，在分支血管的附近发生病变时，采用主体支架对血管病变处进行治疗，会封闭分支血管的血流，造成分支血管闭塞或供血不足。
请参阅图1，病变血管10包括主血管110及分支血管120。分支血管120从主血管110延伸而出，分支血管120与主血管110连接形成有交叉口111，在靠近交叉口111处的主血管110的血管壁上形成病变112。请一并参阅图2，一种常用的方法是在对病变血管10进行重建时，在主血管110中置入主体支架200，并在主体支架200位于交叉口110处进行原位开窗扩孔，接着采用分支导丝入路，导入用于分支血管的支架，完成分支血管的重建。
然而这种方式，无法表达用于分支的支架与原位开窗的主体支架的相对位置，导致用于分支血管的支架进入主体支架的位置不确定，当用于分支血管的支架进入主体支架的内部过长时，可能导致主体支架内部血流的阻塞，当用于分支血管的支架进入主体支架的内部过短时，可能导致用于分支血管的支架在主体支架中的锚定性变差，且用于分支血管的支架的远端也可能造成远端分支口的堵塞；另外，目前分支血管的重建方式，在分支血管出现扭曲或打结的情况时，也无法进行识别。
发明内容
基于此，有必要针对在分支血管的重建过程中无法表达分支血管进入主体支架的位置，且在分支血管出现扭曲或打结的情况时无法进行识别的问题，提 供一种用于分支血管的支架。
一种用于分支血管的支架，包括支架本体及第一显影件，所述支架本体具有第一端及与所述第一端相对的第二端，所述第一显影件位于所述第一端及所述第二端之间且靠近所述第一端，所述第一显影件包括第一显影部及第二显影部；
所述第一显影部沿第一方向延伸，所述第二显影部沿第二方向延伸，所述第一方向与所述第二方向倾斜相交，且所述第一显影部及所述第二显影部在所述支架本体轴线方向上的长度均不小于0.5mm；
所述第一显影部与所述第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间的距离从所述第一显影部与第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间距离最小的位置到所述第一显影部或所述第二显影部远离所述第一端的一端逐渐增大，且所述第一显影部与所述第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间的最小距离不大于2mm。
在其中一个实施方式中，所述第一显影部及所述第二显影部靠近所述第一端的一端在垂直于所述支架本体轴线方向的平面上的交点之间的距离最小。
在其中一个实施方式中，所述支架本体包括裸支架及覆盖在所述裸支架上的覆膜，所述第一显影部及所述第二显影部均设置于所述裸支架上。
在其中一个实施方式中，所述裸支架包括多个沿轴向排布的波圈，所述波圈包括多个交替设置的波峰和波谷，相邻所述波峰与所述波谷之间通过波杆连接，所述第一显影部设置于所述波杆上，所述第二显影部设置于与所述第一显影部位于同一波圈上的相邻的所述波杆上。
在其中一个实施方式中，所述第一显影部及所述第二显影部的长度为所在的所述波杆的长度的1/2～2/3。
在其中一个实施方式中，所述第一显影部与所述第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间距离最小的位置与所述第一端的距离为5mm～10mm。
在其中一个实施方式中，所述支架本体包括依次连接的近端部、连接部及远端部，所述近端部远离所述连接部的一端形成所述第一端，所述远端部远离 所述连接部的一端形成所述第二端；
所述连接部靠近所述近端部的一端的横截面积小于或等于所述连接部靠近所述远端部的一端的横截面积，且所述连接部靠近所述近端部的一端与所述连接部靠近所述远端部的一端的连线与所述轴向形成0～30°的夹角，所述第一显影件位于所述近端部。
在其中一个实施方式中，还包括第二显影件及第三显影件，所述第二显影件设于所述第一端，所述第三显影件设于所述第二端。
在其中一个实施方式中，还包括套设于所述支架本体的裙边支架，所述裙边支架与所述支架本体连接并向所述第一端延伸，所述第一显影部及所述第二显影部远离所述第一端的一端位于所述裙边支架与所述支架本体的连接处。
在其中一个实施方式中，所述裙边支架包括柔性段及与所述柔性段连接的翻折段，所述柔性段与所述支架本体连接，所述第一显影部或第二显影部远离所述第一端的一端到所述第一显影部与第二显影部在垂直于所述支架本体轴线方向的平面上交点之间距离最小的位置之间的距离等于所述柔性段的轮廓线的长度。
上述用于分支血管的支架通过在第一端和第二端之间设置第一显影件，可以方便观测用于分支血管的支架的中部的情况，能够对用于分支血管的支架在释放中出现的扭曲和打折进行识别，而且第一显影部与第二显影部在垂直于支架本体轴线方向的平面上的交点之间的距离从第一显影部与第二显影部在垂直于支架本体轴线方向的平面上的交点之间距离最小的位置到第一显影部或第二显影部远离第一端的一端逐渐增大，在进行手术时，可以避免主体支架中丝材的显影对用于分支血管的支架的显影件的遮挡和混淆，且有利于在拖动用于分支血管的支架时观察且预判用于分支血管的支架在主体支架中的相对位置，从而进行准确的定位。
附图说明
图1为一实施方式的病变血管的结构示意图；
图2为图1所示的病变血管置入主体支架的结构示意图；
图3为一实施方式的用于分支血管的支架的结构示意图；
图4为图3所示的用于分支血管的支架置入主体支架上的结构示意图；
图5为另一实施方式的用于分支血管的支架在自然状态下的结构示意图；
图6为图5所示的用于分支血管的支架在装鞘时的结构示意图；
图7为图5所示的用于分支血管的支架在装鞘完成时的结构示意图；
图8为图5所示的用于分支血管的支架置入主体支架上的结构示意图；
图9为图8中圈A部分的放大结构示意图。
具体实施方式
为使本发明的上述目的、特征和优点能够更加明显易懂，下面结合附图对本发明的具体实施方式做详细的说明。在下面的描述中阐述了很多具体细节以便于充分理解本发明。但是本发明能够以很多不同于在此描述的其它方式来实施，本领域技术人员可以在不违背本发明内涵的情况下做类似改进，因此本发明不受下面公开的具体实施的限制。
需要说明的是，当元件被称为“固定于”另一个元件，它可以直接在另一个元件上或者也可以存在居中的元件。当一个元件被认为是“连接”另一个元件，它可以是直接连接到另一个元件或者可能同时存在居中元件。本文所使用的术语“垂直的”、“水平的”、“左”、“右”以及类似的表述只是为了说明的目的，并不表示是唯一的实施方式。
除非另有定义，本文所使用的所有的技术和科学术语与属于本发明的技术领域的技术人员通常理解的含义相同。本文中在本发明的说明书中所使用的术语只是为了描述具体的实施例的目的，不是旨在于限制本发明。以上所述实施例的各技术特征可以进行任意的组合，为使描述简洁，未对上述实施例中的各个技术特征所有可能的组合都进行描述，然而，只要这些技术特征的组合不存在矛盾，都应当认为是本说明书记载的范围。
请参阅图3，一实施方式的用于分支血管的支架300包括支架本体310及显影组件320，显影组件320设置于支架本体310上，支架本体310具有第一端316及与第一端相对设置的第二端317。
具体的，支架本体310包括裸支架及覆盖在裸支架上的覆膜315。裸支架包括多个沿轴向排布的波圈312。波圈312包括若干相互交替设置的波峰和波谷，相邻波峰与波谷之间通过波杆连接。在其中一个实施方式中，相邻两个波杆的延长线所形成的夹角的角度为30°～120°。
在图示的实施例中，支架本体310形成有依次连接的近端部3101、连接部3102及远端部3103。其中，近端部3101远离连接部3102的一端形成有第一端316，远端部3103远离连接部3102的一端形成有第二端317。第一端316的覆膜形成花瓣形结构，有利于血液从第一端通过；第二端317的覆膜为平齐结构。
在其中一个实施方式中，近端部3101的横截面积小于远端部3103的横截面积。连接部3102靠近近端部3101的一端的横截面积小于或等于连接部3102靠近远端部3103的一端的横截面积，且连接部3102靠近近端部3101的一端与连接部3102靠近远端部3103的一端的连线与轴向形成0～30°的夹角。进一步的，连接部3102靠近近端部3101的一端与连接部3102靠近远端部3103的一端的连线与轴向形成15°～25°的夹角。上述结构使得主体支架310形成锥形结构，可以增大远端部3103的锚定力，同时可以抑制主动脉博动被传递到用于分支血管的支架的远端部3103。应当知晓，近端部3101、连接部3102及远端部3103仅是为了阐述方便而做的区分，并不代表支架本体310在连接边界被分离断开，支架本体310可以是均匀的一体结构。
显影组件320包括第一显影件321、第二显影件322及第三显影件323。第一显影件321位于第一端316与第二端317之间且靠近第一端316。具体的，第一显影件321位于近端部3101。第二显影件322设于第一端316，第三显影件323设于第二端317。第二显影件322用于表征用于分支血管的支架300的起始端。第三显影件323用于表征用于分支血管的支架300的终止端。
在图示的实施例中，显影组件320设于支架本体310的裸支架上。可以理解的是，在其他实施例中，显影组件320中的至少一个显影件还可以形成于覆膜315上。
请继续参阅图3，第一显影件321包括第一显影部3211及第二显影部3212，第一显影部3211沿第一方向延伸，第二显影部3212沿着第二方向延伸，第一 方向与第二方向倾斜相交，且第一显影部3211及第二显影部3212在支架本体310轴线方向上的长度均不小于0.5mm。第一显影部3211与第二显影部3212在垂直于支架本体310轴线方向的平面上的交点之间的距离从第一显影部3211及第二显影部3212在垂直于支架本体310轴线方向的平面上的交点之间距离最小的位置到第一显影部3211或第二显影部3212远离第一端逐渐增大，且第一显影部3211与第二显影部3212在垂直于支架本体310轴线方向的平面上的交点之间的最小距离不大于2mm。
具体的，第一显影部3211及第二显影部3212靠近第一端316的一端在垂直于支架本体310轴线方向的平面上的交点之间的距离最小。在本实施例中，第一显影部3211及第二显影部3212关于支架本体310的轴线对称。
需要说明的是，第一显影部3211及第二显影部3212在垂直于支架本体310轴线方向的平面上的交点之间的距离最小位置处也可以位于第一显影部3211和/或第二显影部3212的中部。
第一显影部3211及第二显影部3212均设置在裸支架上。在图示的实施例中，第一显影部3211设置于波圈312的一个波杆上，第二显影部3212设置于波圈312上与第一显影部3211相邻的波杆上。第一显影部3211及第二显影部3212分别通过在对应的波杆上缠绕显影材料(例如钽丝等)形成。进一步的，第一显影部3211及第二显影部3212的长度为所在的波杆的长度的1/2～2/3，以便于装鞘。优选的，第一显影部3211及第二显影部3212均从靠近波峰的位置向波谷的方向延伸，且第一显影部3211及第二显影部3212波峰处不连接。即，第一显影部3211及第二显影部3212形成“\/”型结构，端点处之间具有间隙。在本实施例中，第一显影部3211及第二显影部3212的长度均为2～4mm。
可以理解的是，在其他实施例中，第一显影部3211与第二显影部3212也可以相互连接形成V型结构。
请参阅图3，第一显影部3211与第二显影部3212在垂直于支架本体310轴线方向的平面上的交点之间距离最小位置处与第一端的距离为5～10mm，可以使得用于分支血管的支架300的一端超出主体支架200之间的长度为5～10mm，这样可以避免用于分支血管的支架300从主体支架200上脱落，也可以减小用于 分支血管的支架300对于主体支架200血流的影响。
第二显影件322及第三显影件323也设置在波圈的波杆上。第二显影件322设置于靠近第一端316的第一个波圈上，第三显影件323设置于靠近第二端317的第一个波圈上。第二显影件322及第三显影件323均可以通过在波杆上缠绕显影材料形成。在本实施例中，第二显影件322及第三显影件323均为I型结构。第二显影件322及第三显影件323的长度可以均为所在波杆长度的1/2～2/3。在本实施例中，第二显影件322及第三显影件323的长度均为2～4mm。
需要说明的是，第二显影件322及第三显影件323还可以为其他结构，其数量也可以为多个。
请一并参阅图4，当采用上述用于分支血管的支架300进行血管重建时，首先在病变处完全释放主体支架200，然后在主体支架200位于分支血管的交叉口111处进行原位开窗器械扩孔至预设孔径；然后，沿着分支导丝入路，采用鞘管将用于分支血管的支架300从分支血管中送入。在用于分支血管的支架300的置入中，第一端316为用于分支血管的支架300移动的前端，置入用于分支血管的支架300直至第一显影部3211或第二显影部3212靠近第一端316的一端完全进入主体支架200时完成置入的初始定位；然后开始将用于分支血管的支架300从鞘管中释放，至第一显影部3211或第二显影部3212远离第一端316从鞘管中刚好释放出来时停止释放；再锁紧鞘管的释放装置，拖动鞘管和用于分支血管的支架300在分支血管中向着分支血管远离主血管的一端移动，移动至第一显影部3211及第二显影部3212在垂直于支架本体310轴线方向的平面上的交点距离最小位置处正好与交叉口111的口壁齐平时，停止拖动，并将用于分支血管的支架300完全从鞘管中释放，以实现分支血管的重建。
上述用于分支血管的支架300通过在第一端316和第二端317之间设置第一显影件321，可以方便观测用于分支血管的支架300的中部的情况，能够对用于分支血管的支架300在释放中出现的扭曲和打折进行识别，还能定位用于分支血管的支架300伸进主体支架200中的长度，而且第一显影部3211与第二显影部3212在垂直于支架本体310轴线方向的平面上的交点之间的距离从第一显影部3211与第二显影部3212在垂直于支架本体轴线方向的平面上的交点之间 距离最小的位置到第一显影部3211或第二显影部3212远离第一端的一端逐渐增大，在进行手术时，当第一显影部3211与第二显影部3212从主体支架200内部移动出来，可以避免主体支架200中丝材的显影对用于分支血管的支架300的显影件的遮挡和混淆，再通过渐变的第一显影件321，有利于在拖动用于分支血管的支架300时观察且预判用于分支血管的支架300在主体支架200中的相对位置，从而进行准确的定位。
请参阅图5，另一实施方式的用于分支血管的支架400包括支架本体410、显影件420及裙边支架430。
在图示的实施方式中，支架本体410及显影件420的结构和上一实施方式中的基本相同，在此不再赘述。
在图示的实施方式中，裙边支架430套设在支架本体410的外侧，且裙边支架430的一端与支架本体410连接，裙边支架430的另一端形成开口端，开口端朝向第一端416。
请继续参阅图5，裙边支架430包括柔性段431及与柔性段431连接的翻折段432。柔性段431与支架本体410连接，且柔性段431与支架本体410通过连接带434连接，连接带434用于支架本体410与柔性段431的连接和支撑，且连接带434可以采用缝合、缠绕、切割或覆膜的方式形成。请参阅图6，第一显影部4211与第二显影部4212远离第一端416的一端位于裙边支架430与支架本体410的连接处，即第一显影部4211与第二显影部4212远离第一端416的一端与连接带434齐平。
在图示的实施方式中，翻折段432与柔性段431远离连接带434的一端转动连接从而使得翻折段432可以收拢或翻折。进一步的，第一显影部4211或第二显影部4212远离第一端416的一端到第一显影部4211与第二显影部4212在垂直于支架本体410的轴线方向的平面上交点之间距离最小的位置之间的距离等于柔性段431的轮廓线的长度，即，装入鞘管后，第一显影部4211与第二显影部4212在垂直于支架本体410的轴向方向的平面上交点之间距离最小的位置与柔性段431远离支架本体410的一端齐平，以便于通过第一显影部4211及第二显影部4212指示柔性段431的起始位置。在本实施例中，当柔性段431远离 连接带434的一端向着靠近第一端416延伸至于支架本体410抵接时，柔性段431靠近第一端416的一端与第一显影部4211或第二显影部4212靠近第一端416的一端齐平。
在其中一个实施方式中，当裙边支架430展开至最大位置时，翻折段432远离柔性段431的一端的直径(即翻折段432远离柔性段431的一端在垂直于支架本体410的平面上的投影的距离)为所在位置的支架本体410的直径的1.5倍～3倍。裙边支架430的直径大于所在位置的支架本体410的直径，如此的设计能够有效降低因支架之间的配合而产生的内漏风险。优选的，翻折段432的长度小于柔性段431的长度。
请一并参阅图5至图7，将用于分支血管的支架400在自然状态下时，柔性段431展开，翻折段432也向着远离支架本体410的方向翻转使得裙边支架430翻折。将自然状态下的用于分支血管的支架400进行装鞘时，支架本体410的第二端417首先进入鞘管，直至连接带434进入鞘管后，柔性段431在鞘管内壁推动下收拢至与支架本体410贴合，此时，翻折段432仍处于展开状态。继续进行装鞘，鞘管内壁推动翻折段432收拢至与主体支架410贴合从而达到图7所示的状态完成用于分支血管的支架的装鞘过程。
请一并参阅图8和图9，在进行手术时，当采用上述用于分支血管的支架400进行血管重建时，首先在病变处完全释放主体支架200，然后在主体支架200位于分支血管的交叉口111处进行原位开窗器械扩孔至预设孔径；然后沿着分支导丝入路，采用鞘管将用于分支血管的支架400从分支血管中送入。在用于分支血管的支架400的置入中，第一端416为用于分支血管的支架400移动的前端，置入用于分支血管的支架400至第一显影部4211及第二显影部4212完全进入主体支架200后完成置入的初始定位；然后开始将用于分支血管的支架400从鞘管中释放，至第一显影部4211或第二显影部4212远离第一端416处刚好释放时停止释放，释放出裙边支架430；再锁紧鞘管的释放装置，拖动鞘管和用于分支血管的支架400在分支血管中向着分支血管远离主血管的一端移动，移动至第一显影部4211及第二显影部4212在垂直于支架本体410轴线方向的平面上的交点距离最小位置处正好与交叉口111的口壁齐平时，停止拖动，此 时，柔性段431因受到挤压会贴住主体支架200的内侧，对交叉口111位置进行有效封堵；最后，将用于分支血管的支架400完全从鞘管中释放。
以上所述实施例的各技术特征可以进行任意的组合，为使描述简洁，未对上述实施例中的各个技术特征所有可能的组合都进行描述，然而，只要这些技术特征的组合不存在矛盾，都应当认为是本说明书记载的范围。
以上所述实施例仅表达了本发明的几种实施方式，其描述较为具体和详细，但并不能因此而理解为对发明专利范围的限制。应当指出的是，对于本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干变形和改进，这些都属于本发明的保护范围。因此，本发明专利的保护范围应以所附权利要求为准。

Claims (10)

  1. 一种用于分支血管的支架，其特征在于，包括支架本体及第一显影件，所述支架本体具有第一端及与所述第一端相对的第二端，所述第一显影件位于所述第一端及所述第二端之间且靠近所述第一端，所述第一显影件包括第一显影部及第二显影部；
    所述第一显影部沿第一方向延伸，所述第二显影部沿第二方向延伸，所述第一方向与所述第二方向倾斜相交，且所述第一显影部及所述第二显影部在所述支架本体轴线方向上的长度均不小于0.5mm；
    所述第一显影部与所述第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间的距离从所述第一显影部与第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间距离最小的位置到所述第一显影部或所述第二显影部远离所述第一端的一端逐渐增大，且所述第一显影部与所述第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间的最小距离不大于2mm。
  2. 根据权利要求1所述的用于分支血管的支架，其特征在于，所述第一显影部及所述第二显影部靠近所述第一端的一端在垂直于所述支架本体轴线方向的平面上的交点之间的距离最小。
  3. 根据权利要求1所述的用于分支血管的支架，其特征在于，所述支架本体包括裸支架及覆盖在所述裸支架上的覆膜，所述第一显影部及所述第二显影部均设置于所述裸支架上。
  4. 根据权利要求3所述的用于分支血管的支架，其特征在于，所述裸支架包括多个沿轴向排布的波圈，所述波圈包括多个交替设置的波峰和波谷，相邻所述波峰与所述波谷之间通过波杆连接，所述第一显影部设置于所述波杆上，所述第二显影部设置于与所述第一显影部位于同一波圈上的相邻的所述波杆上。
  5. 根据权利要求4所述的用于分支血管的支架，其特征在于，所述第一显影部及所述第二显影部的长度为所在的所述波杆的长度的1/2～2/3。
  6. 根据权利要求1所述的用于分支血管的支架，其特征在于，所述第一显影部与所述第二显影部在垂直于所述支架本体轴线方向的平面上的交点之间距 离最小的位置与所述第一端的轴向距离为5mm～10mm。
  7. 根据权利要求1所述的用于分支血管的支架，其特征在于，所述支架本体包括依次连接的近端部、连接部及远端部，所述近端部远离所述连接部的一端形成所述第一端，所述远端部远离所述连接部的一端形成所述第二端；
    所述连接部靠近所述近端部的一端的横截面积小于或等于所述连接部靠近所述远端部的一端的横截面积，且所述连接部靠近所述近端部的一端与所述连接部靠近所述远端部的一端的连线与所述轴向形成0～30°的夹角，所述第一显影件位于所述近端部。
  8. 根据权利要求1～7任一项所述的用于分支血管的支架，其特征在于，所述的用于分支血管的支架还包括第二显影件及第三显影件，所述第二显影件设于所述第一端，所述第三显影件设于所述第二端。
  9. 根据权利要求1～7任一项所述的用于分支血管的支架，其特征在于，所述的用于分支血管的支架还包括套设于所述支架本体的裙边支架，所述裙边支架与所述支架本体连接并向所述第一端延伸，所述第一显影部及所述第二显影部远离所述第一端的一端位于所述裙边支架与所述支架本体的连接处。
  10. 根据权利要求9所述的用于分支血管的支架，其特征在于，所述裙边支架包括柔性段及与所述柔性段连接的翻折段，所述柔性段与所述支架本体连接，所述第一显影部或所述第二显影部远离所述第一端的一端到所述第一显影部与第二显影部在垂直于所述支架本体轴线方向的平面上交点之间距离最小的位置之间的距离等于所述柔性段的轮廓线的长度。
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US11529248B2 (en) 2022-12-20
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EP3733121A1 (en) 2020-11-04
CN109984864B (zh) 2020-07-17
US12156823B2 (en) 2024-12-03
PL3733121T3 (pl) 2022-11-07
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US20230078930A1 (en) 2023-03-16
CN109984864A (zh) 2019-07-09

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