WO2022028070A1 - 体液分析物检测器件 - Google Patents

体液分析物检测器件 Download PDF

Info

Publication number
WO2022028070A1
WO2022028070A1 PCT/CN2021/097188 CN2021097188W WO2022028070A1 WO 2022028070 A1 WO2022028070 A1 WO 2022028070A1 CN 2021097188 W CN2021097188 W CN 2021097188W WO 2022028070 A1 WO2022028070 A1 WO 2022028070A1
Authority
WO
WIPO (PCT)
Prior art keywords
transmitter
bottom case
detection device
analyte detection
body fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2021/097188
Other languages
English (en)
French (fr)
Inventor
杨翠军
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtrum Technologies Inc
Original Assignee
Medtrum Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtrum Technologies Inc filed Critical Medtrum Technologies Inc
Priority to EP21854556.4A priority Critical patent/EP4190237A4/en
Priority to US18/015,331 priority patent/US20230210408A1/en
Priority to PCT/CN2021/136493 priority patent/WO2022252548A1/en
Priority to EP21943900.7A priority patent/EP4346586A4/en
Priority to US18/562,836 priority patent/US20240225492A1/en
Priority to US18/562,838 priority patent/US20240266661A1/en
Priority to PCT/CN2021/136533 priority patent/WO2022252550A1/en
Priority to EP21943902.3A priority patent/EP4346588A4/en
Priority to PCT/CN2021/136506 priority patent/WO2022252549A1/en
Priority to EP21943901.5A priority patent/EP4346587A4/en
Priority to US18/562,842 priority patent/US20240237926A1/en
Priority to CN202111490401.6A priority patent/CN115474932B/zh
Priority to CN202111492198.6A priority patent/CN115483489B/zh
Priority to CN202111490408.8A priority patent/CN115483485B/zh
Priority to US18/562,337 priority patent/US20240260862A1/en
Priority to CN202111651908.5A priority patent/CN115475303A/zh
Priority to CN202111656191.3A priority patent/CN115475304A/zh
Priority to EP21943957.7A priority patent/EP4346589A4/en
Priority to PCT/CN2021/143067 priority patent/WO2022252605A1/en
Priority to PCT/CN2021/143074 priority patent/WO2022252606A1/en
Priority to EP21943958.5A priority patent/EP4346590A4/en
Priority to US18/562,840 priority patent/US20240285193A1/en
Publication of WO2022028070A1 publication Critical patent/WO2022028070A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/002—Monitoring the patient using a local or closed circuit, e.g. in a room or building
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6838—Clamps or clips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • A61B5/6849—Needles in combination with a needle set
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic using feedback of body parameters, e.g. blood sugar or pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505—Flexible containers without fluid transport within
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M50/00—Constructional details or processes of manufacture of the non-active parts of electrochemical cells other than fuel cells, e.g. hybrid cells
    • H01M50/20—Mountings; Secondary casings or frames; Racks, modules or packs; Suspension devices; Shock absorbers; Transport or carrying devices; Holders
    • H01M50/247—Mountings; Secondary casings or frames; Racks, modules or packs; Suspension devices; Shock absorbers; Transport or carrying devices; Holders specially adapted for portable devices, e.g. mobile phones, computers, hand tools or pacemakers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M50/00—Constructional details or processes of manufacture of the non-active parts of electrochemical cells other than fuel cells, e.g. hybrid cells
    • H01M50/20—Mountings; Secondary casings or frames; Racks, modules or packs; Suspension devices; Shock absorbers; Transport or carrying devices; Holders
    • H01M50/271—Lids or covers for the racks or secondary casings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0204—Operational features of power management
    • A61B2560/0214—Operational features of power management of power generation or supply
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0443—Modular apparatus
    • A61B2560/045—Modular apparatus with a separable interface unit, e.g. for communication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0462—Apparatus with built-in sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0462—Apparatus with built-in sensors
    • A61B2560/0468—Built-in electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/22—Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
    • A61B2562/225—Connectors or couplings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/22—Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
    • A61B2562/225—Connectors or couplings
    • A61B2562/227—Sensors with electrical connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0233—Conductive materials, e.g. antistatic coatings for spark prevention
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/023—Sending and receiving of information, e.g. using Bluetooth®
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/10—Energy storage using batteries

Definitions

  • the invention mainly relates to the field of medical devices, and in particular to a body fluid analyte detection device.
  • the pancreas in a normal human body can automatically monitor the glucose level in the human blood and secrete the required insulin/glucagon automatically.
  • the pancreas does not function properly and cannot secrete insulin normally. Therefore, diabetes is a metabolic disease caused by abnormal pancreatic function in the human body, and diabetes is a lifelong disease.
  • medical technology cannot cure diabetes, and the occurrence and development of diabetes and its complications can only be controlled by stabilizing blood sugar.
  • CGM Continuous Glucose Monitoring
  • the existing body fluid analyte detection device cannot achieve good waterproof effect.
  • water droplets will enter the detection device. Once in contact with the electrical connection area, it will cause a short circuit fault or current Intensity disturbance affects the accuracy and reliability of detection. Therefore, users often need to remove the detection device from the body before performing underwater activities, causing great inconvenience.
  • the embodiment of the present invention discloses a body fluid analyte detection device.
  • a waterproof structure is arranged in the electrical connection area in the body fluid analyte detection device.
  • the waterproof structure includes a groove and a sealing ring arranged on the bottom case. One end of the sealing ring is placed in the groove, and the other end is in contact with the transmitter housing to prevent water droplets. Enter the electrical connection area to avoid short circuit and current intensity disturbance. Users do not need to remove the detector from the body when bathing, washing, swimming and other underwater actions, which enhances the user experience and improves the reliability of detection data.
  • the invention discloses a body fluid analyte detection device, comprising: a transmitter, on which at least one first engaging part is arranged; and a bottom case, on which a second card corresponding to the first engaging part is arranged
  • the first engaging portion and the second engaging portion are engaged with each other, and the transmitter can be assembled on the bottom case.
  • the bottom case includes a fixing portion and a force-applying portion. When the bottom case and the transmitter are separated, the fixing portion is fixed.
  • the bottom case fails, and at least a pair of the first engaging part and the second engaging part that are engaged with each other are separated from each other, and then the bottom case and the transmitter are separated;
  • the sensor on the bottom case includes a probe and a conductive strip, the probe is used to detect the parameter information of the body fluid analyte, and is electrically connected to the transmitter through the conductive strip to transmit the parameter signal; the battery is electrically connected to the transmitter for The transmitter provides electrical energy;
  • the waterproof structure includes a groove and a sealing ring arranged on the bottom case, the lower end face of the sealing ring is placed in the groove, and the upper end face is in contact with the shell of the transmitter, and is used for the body fluid analyte
  • the electrical connection area of the detection device provides protection against water.
  • the battery is sealed in the bottom case to form a battery sealing chamber, and at least two electrodes are drawn out from the battery sealing chamber, and the electrodes include at least one positive electrode and one negative electrode.
  • the waterproof structure is located at the electrical connection area of the emitter with the positive and negative electrodes.
  • the sealing ring may provide a spring force that facilitates separation of the launcher and the bottom case.
  • the electrodes are elastic conductive materials.
  • the sealing ring is an insulating rubber ring.
  • the upper end face of the sealing ring is higher than the upper end face of the groove.
  • sealing rings which are respectively located on the upper and lower sides of the probe.
  • a side edge of the bottom case is provided with an outward convex portion, and the convex portion is the force applying portion.
  • a sealing ring is provided around the connection hole to seal the electrical connection position, and when a force is applied to the force applying part, the sealing ring provides an elastic force to promote the separation of the bottom case and the launcher.
  • the invention also discloses a continuous glucose monitoring device, comprising the above-mentioned body fluid analyte detection device, and a receiver for receiving the parameter signal transmitted by the transmitter.
  • a waterproof structure is arranged in each electrical connection area to prevent water droplets from entering the electrical connection area and avoid short circuit and current intensity disturbance. , the detector does not need to be removed from the body, which enhances the user experience. On the other hand, it reduces the interference of the detection data beating caused by the disturbance of the current intensity, and improves the reliability of the detection data.
  • the transmitter is provided with at least one first engaging portion
  • the bottom case is provided with a second engaging portion corresponding to the first engaging portion
  • the bottom case includes a fixing portion and a force applying portion
  • the bottom case is separated.
  • the battery can be sealed in the bottom case and discarded with the bottom case.
  • the user replaces the battery every time the bottom case is replaced, and the battery always maintains a high-performance working state.
  • a waterproof structure is arranged in the electrical connection area between the transmitter and the battery extraction electrode to prevent water droplets from entering the electrical connection area and avoid short circuit and current intensity disturbance.
  • the sealing ring is made of insulating rubber. Since the rubber is a flexible material and has a certain compressive elasticity, the transmitter has a certain pressing force on the sealing ring when it is installed on the bottom case, which can better maintain the sealing ring and the transmitter. The close contact of the shell prevents water droplets from entering the electrical connection area, avoiding short circuit and current intensity disturbance.
  • the first engaging portion and the second engaging portion are separated from each other, and the sealing ring can promote the separation of the transmitter and the bottom case.
  • the diameter of the sealing ring is larger than the inner diameter of the groove, and the sealing ring can be more tightly fixed in the groove, thereby increasing the reliability of the waterproof structure.
  • the upper end surface of the sealing ring is higher than the upper end surface of the groove, and the transmitter housing and the sealing ring can be in closer contact, thereby increasing the reliability of the waterproof structure.
  • FIG. 1a is a schematic structural diagram of a body fluid analyte detection device according to an embodiment of the present invention
  • FIG. 2 is a schematic three-dimensional structure diagram of a sensor according to an embodiment of the present invention.
  • 3a is a schematic cross-sectional structure diagram of an electrical connection area of a sensor according to an embodiment of the present invention.
  • 3b is a schematic cross-sectional structural diagram of a waterproof structure in an electrical connection area of a sensor according to an embodiment of the present invention
  • 3c is a schematic cross-sectional structural diagram of the waterproof structure in the electrical connection area of the sensor after the transmitter is installed according to an embodiment of the present invention
  • FIG. 4 is a top view of a bottom case with a battery according to an embodiment of the present invention.
  • 5a is a schematic cross-sectional structure diagram of an electrode electrical connection region according to an embodiment of the present invention.
  • 5b is a schematic cross-sectional structural diagram of a waterproof structure in an electrode electrical connection area according to an embodiment of the present invention
  • 5c is a schematic cross-sectional structural diagram of the waterproof structure of the electrode electrical connection area after the transmitter is installed according to an embodiment of the present invention
  • FIG. 6 is a schematic diagram of a continuous glucose monitoring device according to one embodiment of the present invention.
  • the present invention provides a body fluid analyte detection device.
  • a waterproof structure is provided in each electrical connection area to prevent water droplets from entering the electrical connection area, so as to avoid short circuit and current intensity disturbance. Users are bathing, rinsing, swimming, etc. During underwater action, the detector does not need to be removed from the body, which enhances the user experience and improves the reliability of detection data.
  • FIG. 1a is a schematic three-dimensional structure diagram of a body fluid analyte detection device according to an embodiment of the present invention.
  • the detection device includes a bottom case 10 , a sensor 11 and a transmitter 12 .
  • the bottom case 10 is used for assembling the transmitter 12 and the sensor 11, and the detection device is pasted on the skin surface through the bottom adhesive tape (not shown in the figure).
  • the bottom case 10 includes a fixing portion and a force applying portion.
  • the bottom case 10 is provided with at least one second engaging portion 101.
  • the second engaging portion 101 is used for engaging the transmitter 12 .
  • the number of the second engaging portions 101 is two, and the two second engaging portions 101 are correspondingly disposed on the side walls of the bottom case 10 .
  • the fixed portion and the biasing portion are relative concepts. According to the structural design of the bottom case 10 and the transmitter 12, the positions of the fixing portion and the force applying portion can be selected differently, which will be described in detail below.
  • the connecting line 1 of the two second engaging portions 101 divides the bottom case 10 into an A side and a B side.
  • the A side is provided with the urging part, and the B side is provided with the fixing part.
  • the process of separating the bottom case 10 and the transmitter 12 is as follows: use a finger to fix the fixing part on the B side, and use another finger to apply a force F to the force application part in one direction, so that the second card
  • the engaging portion 101 fails, the second engaging portion 101 and the first engaging portion 121 are further separated, so that the transmitter 12 is separated from the bottom case 10 .
  • the number of the second engaging portions 101 is four, and the four second engaging portions 101 are correspondingly disposed on the opposite side walls of the bottom case 10 , two on each side.
  • the number of the second engaging portions 101 is six, and the six second engaging portions 101 are correspondingly disposed on the side walls of the bottom case 10 , two on each side.
  • the embodiments of the present invention do not specifically limit the shape of the top view of the detection device, and the shape may also be a rounded rectangle, a rectangle, a circle, an ellipse, or other shapes.
  • At least one first engaging portion 121 is disposed on the transmitter 12 .
  • the first engaging portion 121 corresponds to the second engaging portion 101 .
  • the transmitter 12 is assembled on the bottom case 10 by engaging the second engaging portion 101 and the first engaging portion 121 with each other.
  • the transmitter 12 is provided with two first engaging portions 121 , that is, two pairs of the first engaging portions 121 and the second engaging portions 101 that engage with each other.
  • the correspondence between the first engaging portion 121 and the second engaging portion 101 means that the two are equal in number and corresponding in position.
  • the fixing part is fixed by a finger or other equipment, and another finger or other auxiliary equipment is used to exert force on the force-applying part in one direction, the bottom case 10 will fail, and the second The engaging portion 101 and the first engaging portion 121 are separated from each other, thereby separating the transmitter 12 from the bottom case 10 . That is, when the user separates the bottom case 10 and the transmitter 12, only one finger can apply force to the force applying part in one direction, and the two can be separated, which is convenient for the user to operate. After separation, the transmitter can be reused, reducing the cost for the user.
  • failure is a conventional concept in the field of engineering materials. After failure, the material loses its original function, and the failed part cannot be restored again. Since the second engaging portion 101 is a part of the bottom case 10 , the failure of the bottom case 10 includes the failure of the bottom plate, the side wall or the second engaging portion 101 of the bottom case 10 . Therefore, the failure modes of the bottom case 10 include one or more of the bottom or side walls of the bottom case 10 being broken, the bottom case 10 being broken, the second engaging portion 101 being broken, and the bottom case 10 being plastically deformed. Obviously, after the bottom case 10 fails, the bottom case 10 loses the function and function of the engaging transmitter 12 .
  • the manner of fixing the fixing portion includes clamping, supporting and other manners, which are not specifically limited here, as long as the conditions for fixing the fixing portion can be met.
  • the senor 11 is installed on the bottom case 10, and at least includes a probe 113 and a conductive rubber strip 114.
  • the probe 113 is used to penetrate the human skin, detect the parameter information of the body fluid analyte, and convert it into an electrical signal , the electrical signal is transmitted to the conductive electrode 122 of the transmitter 12 through the conductive rubber strip 114, and the transmitter 12 transmits the parameter information of the body fluid analyte to the user.
  • the battery is located in the housing of the transmitter 12 to form a good waterproof seal.
  • the conductive electrode 122 is electrically connected to the conductive rubber strip 114 .
  • a groove 131 is provided on the sensor bottom case 111 and around the conductive rubber strip 114 for placing the sealing ring 130 . The outline of the sealing ring and the groove outline are consistent.
  • the contour of the sealing ring and the contour of the groove may also be inconsistent, for example, the groove is a square, a circle, an arc or a combination thereof, and the corresponding sealing ring is a circle, an arc, a square or a combination thereof shape.
  • FIGS. 3 a , 3 b and 3 c For a clearer understanding of the waterproof principle of the waterproof structure composed of the groove 131 and the sealing ring 130 , please refer to FIGS. 3 a , 3 b and 3 c .
  • Fig. 3a is a C-C' sectional view of the sensor 11 shown in Fig. 2 before the sealing ring 130 is installed.
  • the probe 113 is divided into an internal part 113b and an external part 113a.
  • the external part 113a is bent or bent toward the upper end of the bottom case 111 and is laid flat on the bottom case 111 .
  • Fig. 3b is a CC' sectional view of the sensor 11 shown in Fig. 2 after the sealing ring 131 is installed.
  • 114 and the upper end surface of the sealing ring 130 is slightly higher than the upper end surface of the conductive rubber strip 114 .
  • 3c is a CC' cross-sectional view of the sensor 11 shown in FIG. 2 after the sealing ring 131 and the transmitter 12 are installed.
  • the conductive electrode 122 is in contact with the conductive rubber strip 114
  • the transmitter housing is in contact with the upper surface of the sealing ring 130. It is envisioned that the transmitter housing 12, the sealing ring 130 and the groove 131 may form a sealed chamber 132 within which the probe body portion 113a, the conductive strip 114 and the conductive electrode 122 are located.
  • the water droplets are blocked by the transmitter housing 12 , the sealing ring 130 and the groove 131 and cannot enter the chamber 132 , thereby electrically connecting the conductive electrodes 122 and the conductive rubber strips 114 area to form waterproof protection.
  • the size of the sealing ring is slightly larger than the size of the groove, so that the sealing ring 130 can be installed in the groove 131 more tightly, and it is not easy to fall off, and the edge of the sealing ring 130 can form a more airtight connection with the groove 131 contact, to achieve a more ideal waterproof protection.
  • a layer of sealing ring (not shown in the figure) can also be added under the probe body part 113a and above the bottom shell 111, which together with the seal ring and the groove above the probe body part 113a form a waterproof layer
  • the structure can better prevent water droplets from entering the electrical connection area, and has a better waterproof effect.
  • the material of the sealing ring is preferably insulating rubber. Since the rubber is a flexible material and has a certain compressive elasticity, the transmitter 12 has a certain pressing force on the sealing ring 130 when it is installed on the bottom case 10 . , which can better keep the sealing ring 130 in close contact with the housing of the transmitter 10 , prevent water droplets from entering the electrical connection area, and avoid short circuit and current intensity disturbance.
  • the second engaging portion 101 and the first engaging portion 121 are separated from each other, and the compressive elasticity of the sealing ring 130 can promote the separation of the bottom case 10 and the transmitter 12 .
  • Figure 1b is a schematic structural diagram of a body fluid analyte detection device according to another embodiment of the invention.
  • the detection device includes a bottom case 20 , a sensor 11 and a transmitter 22 .
  • the fixing portion and the force applying portion are relative concepts. According to the structural design of the bottom case 20 and the transmitter 22, the positions of the fixing part and the force applying part can be selected differently.
  • the connecting line l1 of the two second engaging portions 202 divides the bottom case 20 into an A side and a B side.
  • the A side is provided with the urging part, and the B side is provided with the fixing part.
  • the process of separating the bottom case 20 and the transmitter 22 is as follows: use a finger to fix the fixing part on the B side, and use another finger to apply a force F to the force application part in one direction, so that the second card
  • the engaging portion 202 fails, the second engaging portion 202 and the first engaging portion 221 are separated, so that the transmitter 22 is separated from the bottom case 20 .
  • the number of the second engaging portions 202 is two, and the two second engaging portions 202 are correspondingly disposed on the side walls of the bottom case 10 .
  • the number of the second engaging portions 202 is four, and the four second engaging portions 202 are correspondingly disposed on the opposite side walls of the bottom case 10 , two on each side.
  • the number of the second engaging portions 202 is six, and the six second engaging portions 202 are correspondingly disposed on the side walls of the bottom case 10 , two on each side.
  • the embodiments of the present invention do not specifically limit the shape of the top view of the detection device, and the shape may also be a rounded rectangle, a rectangle, a circle, an ellipse, or other shapes.
  • the detection device of the embodiment of the present invention further includes a battery 208 .
  • a battery 208 is used to power the transmitter and is located in the bottom case 20 .
  • the part of the bottom case 20 where the battery 208 is arranged is the battery sealing chamber 203 .
  • the battery 208 can be replaced at the same time every time the bottom case 20 is replaced, and the transmitter 22 can be used repeatedly because the battery is no longer provided, which reduces the cost of replacing the transmitter 22 by the user.
  • the battery can ensure the continuous high-performance working state of the transmitter 22 .
  • the top of the battery sealing chamber 203 is flush with the top of the emitter 22, so that the thickness dimension of the detection device can be reduced.
  • the battery sealing chamber 203 can be directly used as the force applying part, therefore, the battery is arranged on the A side of l1 . Since the battery sealing chamber 203 is relatively thick and has a relatively large area, as a force applying part, it is easier for the user to apply force on the battery sealing chamber 203, thereby optimizing the user's operation steps.
  • FIG. 4 is a top view of the bottom case 20 .
  • the bottom case 20 is further provided with at least two electrodes 204 .
  • the electrical contacts 223 of the transmitter 22 are respectively electrically connected to the positive and negative electrodes of the battery through the electrodes 204 to form an electrical connection area.
  • the battery 208 supplies power to the transmitter through the electrodes 204 and the electrical contacts 223. Once the water droplets enter the electrical connection area, a short circuit occurs, resulting in unstable power supply to the battery 208 and fluctuations in the current intensity received by the transmitter 22, which may cause the transmitter 22 to receive
  • the body fluid analyte parameter information and the transmitted parameter information of the probe 113 jump, which affects the reliability of the analyte detection device. Therefore, the electrical connection area needs to be protected against water.
  • the waterproof structure of the electrical connection area includes a groove 207 and a sealing ring 205 .
  • FIG. 5a For a clearer understanding of the waterproof principle of the waterproof structure composed of the groove 207 and the sealing ring 205, refer to FIG. 5a, FIG. 5b, and FIG. 5c.
  • FIG. 5a is a DD' cross-sectional view of the bottom case 20 shown in FIG. 4 before the sealing ring 205 is installed.
  • the battery 208 is placed in the battery sealing chamber 203.
  • the battery sealing chamber 203 is formed by the positive and negative conductive strips 209 of the battery 208. It is formed with the shell of the bottom case 20 to form a completely closed space, and water droplets cannot enter the battery sealing chamber.
  • 204 is located in the middle of the groove 207, and one end is fixed on the positive and negative conductive strips 209.
  • Figure 5b is a DD' cross-sectional view of the bottom case 20 shown in Figure 4 after the sealing ring 205 is installed.
  • the sealing ring 205 is located on the upper end face of the groove 207, and its contour is consistent with the groove contour, and can surround the electrode 204,
  • the upper end surface of the sealing ring 205 is slightly higher than the upper end surface of the groove 207 , and “slightly higher” here means that the upper end surface of the sealing ring 205 is 0-5 mm higher than the upper end surface of the groove 207 , preferably 1 mm.
  • Fig. 5c is a DD' cross-sectional view of the bottom case 20 shown in Fig. 4 after the sealing ring 205 and the transmitter 22 are installed.
  • the housing of the transmitter 22, the sealing ring 205, the groove 207 and the positive and negative conductive strips 209 form a sealed chamber 210, and the transmitter power supply electrodes 223 and 204 are located in the sealed chamber within 210.
  • the water droplets are blocked by the housing of the transmitter 22, the sealing ring 205 and the groove 207, and cannot enter the chamber 210, thus affecting the transmitter power electrodes 223, 204, positive and negative
  • the electrical connection area of the extremely conductive strip 209 forms waterproof protection.
  • the size of the sealing ring is slightly larger than the size of the groove, so that the sealing ring 205 can be installed in the groove 207 more tightly, and it is not easy to fall off, and the edge of the sealing ring 205 and the groove 207 can form a more airtight contact, to achieve a more ideal waterproof protection.
  • the electrode 204 is an elastic conductive material that can be electrically connected to the transmitter power supply electrode 223, such as a conductive spring or a conductive elastic sheet.
  • the transmitter power supply electrode 223 squeezes the electrode 204, so that the electrode 204 is continuously compressed and maintains elastic force, so that the electrode 204 can maintain continuous close contact with the transmitter power electrode 223, and ensure that the battery 208 can deliver stable power to the transmitter 22.
  • the material of the sealing ring is preferably insulating rubber. Since the rubber is a flexible material and has a certain compressive elasticity, the transmitter 22 has a certain pressing force on the sealing ring 205 when it is installed on the bottom case 20 . , which can better keep the sealing ring 205 in close contact with the housing of the transmitter 20, prevent water droplets from entering the electrical connection area, and avoid causing short circuit and current intensity disturbance.
  • the waterproof structures of the conductive electrodes 222 of the sensor 11 and the transmitter 22 are the same as those of the first embodiment, and are not repeated here.
  • the pressed sealing ring 105 exerts a certain elastic force on the launcher 22 , and when a force F is applied to the force applying portion, the sealing ring 105 provides elastic force to promote the separation of the launcher 22 from the bottom case 20 .
  • a sealing ring is provided around the sensor. Similar to the above-mentioned sealing ring 105 , when the bottom case 20 is about to fail, the second engaging portion 201 and the first engaging portion 221 are separated from each other.
  • the present invention discloses a body fluid analyte detection device.
  • a waterproof structure is arranged in the electrical connection area of the device to prevent water droplets from entering the electrical connection area, and to avoid short circuits and current intensity disturbances. Users are bathing, rinsing, swimming, etc. During underwater action, the detector does not need to be removed from the body, which enhances the user experience and improves the reliability of detection data.
  • the invention also discloses a continuous glucose monitoring device. As shown in FIG. 6 , the sensor 11 is installed on the bottom case 10 (20), and then the transmitter 12 (22) is installed on the bottom case 20. After the transmitter 12 ( 22) The detection data indication signal of the sensor 11 can be acquired, and the transmitter 12 (22) is then wirelessly connected to the receiver 30 to transmit the detection data indication signal to the receiver 30 for the user to know the detection data.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Electrochemistry (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Emergency Medicine (AREA)
  • Computer Hardware Design (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

一种体液分析物检测器件，包括发射器(12)，发射器上设置有至少一个第一卡合部(121)；底壳(10)上设置有与第一卡合部相对应的第二卡合部(101)，通过第一卡合部与第二卡合部互相卡合，发射器装配于底壳上，底壳包括固定部与施力部，固定固定部，并在一个方向上对施力部施加力的作用，底壳失效，第一卡合部与第二卡合部互相分离，进而分离底壳与发射器；用于向发射器供电的电池(208)；传感器(11)，用于检测体液分析物参数信息，传感器与发射器电连接，以传输参数信号；和防水结构，用于阻止水滴进入到电连接区，提高体液分析物检测器件的使用可靠性，改善用户使用的便利性。

Description

体液分析物检测器件 技术领域
本发明主要涉及医疗器械领域，特别涉及一种体液分析物检测器件。
背景技术
正常人身体中的胰腺可自动监测人体血液中的葡萄糖含量，并自动分泌所需的胰岛素/胰高血糖素。而糖尿病患者胰腺的功能出现异常状况，无法正常分泌人体所需胰岛素。因此糖尿病是人体胰腺功能出现异常而导致的代谢类疾病，糖尿病为终身疾病。目前医疗技术尚无法根治糖尿病，只能通过稳定血糖来控制糖尿病及其并发症的发生和发展。
糖尿病患者在向体内注射胰岛素之前需要检测血糖。目前多数的检测手段可以对血糖连续检测，并将血糖数据实时发送至远程设备，便于用户查看，这种检测方法称为连续葡萄糖检测(Continuous Glucose Monitoring，CGM)法。该方法需要检测器件贴在皮肤表面，将其携带的传感器探头刺入皮下的组织液完成检测。
现有体液分析物检测器件无法做到良好的防水效果，当用户进行沐浴、冲洗、游泳等水下活动时，水滴会进入到检测器件内，一旦与电连接区接触，会引起短路故障或者电流强度扰动，影响检测准确性和可靠性，因此用户往往在进行水下活动前，需要先将检测器件从身上取下，造成极大的不便。
因此，现有技术亟需一种防水性能良好的体液分析物检测器件。
发明内容
本发明实施例公开了一种体液分析物检测器件。在体液分析物检测器件内的电连接区设置防水结构，防水结构包括设置在底壳上的凹槽和密封环，密封环一端放置在凹槽内，另一端与发射器壳体接触，阻止水滴进入电连接区，避免引起短路和电流强度扰动，用户在进行沐浴、冲洗、游泳等水下动作时，无需将检测器从身上取下，增强了用户体验，提高了检测数据的可靠性。
本发明公开了一种体液分析物检测器件，包括：发射器，发射器上设置有至少一个第一卡合部；底壳，底壳上设置有与第一卡合部相对应的第二卡合部，通过第一卡合部与第二卡合部互相卡合，发射器可装配于底壳上，底壳包括固定部与施力部，在分离底壳与发射器时，固定固定部，并在一个方向上对施力部施加力的作用，底壳失效，至少一对互相卡合的第一卡合部与第二卡合部互相分离，进而分离底壳与发射器；安装至底壳上的传感 器，包括探头和导电胶条，探头用于检测体液分析物参数信息，并通过导电胶条与发射器电连接，以传输参数信号；电池，与发射器电连接，用于为发射器提供电能；防水结构，防水结构包括设置在底壳上的凹槽和密封环，密封环的下端面放置于凹槽内，上端面与发射器的壳体接触，用于为体液分析物检测器件的电连接区提供防水保护。
根据本发明的一个方面，电池密封在发射器内，防水结构位于传感器与发射器的电连接区。
根据本发明的一个方面，电池密封在底壳内，形成电池密封腔室，并从电池密封腔室引出至少2个电极，电极至少包括1个正极和1个负极。
根据本发明的一个方面，发射器分别与正极、负极电连接，以获取电池的电能。
根据本发明的一个方面，防水结构位于发射器与正极和负极的电连接区。
根据本发明的一个方面，密封环可提供促进发射器和底壳分离的弹力。
根据本发明的一个方面，电极为弹性导电材料。
根据本发明的一个方面，密封环为绝缘橡胶环。
根据本发明的一个方面，密封环的直径大于凹槽的内径。
根据本发明的一个方面，密封环的上端面高于凹槽的上端面。
根据本发明的一个方面，密封环有2个，分别位于探头的上、下侧。
根据本发明的一个方面，底壳装配发射器的部分为施力部。
根据本发明的一个方面，底壳侧边设置有向外的凸部，所述凸部为所述施力部。
根据本发明的一个方面，电池设置于底壳内，底壳中设置有至少一个连接孔，通过连接孔，发射器与电池的两极电连接，电池部位为施力部。
根据本发明的一个方面，连接孔周围设置有密封圈以密封电连接位置，在对施力部施加作用力时，密封圈提供促进底壳与发射器分离的弹力。
本发明还公开了一种连续葡萄糖监测装置，包括如上所述的体液分析物检测器件，还包括接收器，用于接收发射器传输的参数信号。
与现有技术相比，本发明的技术方案具备以下优点：
本发明公开的体液分析物检测器件中，在各电连接区设置防水结构，阻止水滴进入电连接区，避免引起短路和电流强度扰动，一方面用户在进行沐浴、冲洗、游泳等水下动作时，无需将检测器从身上取下，增强了用户体验，另一方面减少因电流强度扰动带来的检测数据跳动的干扰，提高了检测数据的可靠性。
进一步的，发射器上设置有至少一个第一卡合部，底壳上设置有与第一卡合部相对应的第二卡合部，底壳包括固定部与施力部，在分离底壳与发射器时，固定固定部，并在一 个方向上对施力部施加力的作用，底壳失效，至少一对互相卡合的第一卡合部与第二卡合部互相分离，进而分离底壳与发射器；和用于向发射器供电的电池。只在一个方向上对底壳的施力部施加作用力，即可使底壳失效，进而使第一卡合部与第二卡合部互相分离，发射器能够重复使用；且减少了用户在分离发射器与底壳时的操作步骤，增强了用户体验。
进一步的，电池可直接密封在发射器内，为发射器提供电能，无需额外的防水结构即可实现电池与发射器间的防水效果，避免引起短路而损坏发射器，提高了体液分析物检测器件的可靠性。
进一步的，电池可密封在底壳内，随底壳抛弃，用户每次更换底壳同时更换了电池，电池始终保持高性能工作状态。在发射器和电池引出电极的电连接区设置防水结构，阻止水滴进入电连接区，避免引起短路和电流强度扰动。
进一步的，电极采用导电弹性材料，发射器与电极接触时挤压电极，使电极处于持续压缩状态，缩进凹槽内，并保持弹力，一方面电极与发射器保持紧密接触，保证电能输送的稳定性，另一方面便于发射器壳体与密封环紧密接触，提高防水性能，阻止水滴进入电连接区，避免引起短路和电流强度扰动。
进一步的，密封环采用绝缘橡胶，由于橡胶为柔性材料，且具备一定的抗压弹性，发射器安装到底壳上时对密封环有一定的挤压力，能更好的保持密封环与发射器壳体的紧密接触，阻止水滴进入电连接区，避免引起短路和电流强度扰动。
进一步的，底壳失效时，第一卡合部与第二卡合部相互分离，密封环可促进发射器和底壳分离。
进一步的，密封环直径大于凹槽内径，密封环可以更加紧密的固定在凹槽内，增加防水结构的可靠性。
进一步的，密封环的上端面高于凹槽的上端面，发射器壳体与密封环可以更加紧密的接触，增加防水结构的可靠性。
附图说明
图1a为根据本发明一个实施例体液分析物检测器件的结构示意图；
图1b为根据本发明再一个实施例体液分析物检测器件的结构示意图；
图2为根据本发明一个实施例传感器的立体结构示意图；
图3a为根据本发明一个实施例传感器电连接区的剖面结构示意图；
图3b为根据本发明一个实施例传感器电连接区防水结构的剖面结构示意图；
图3c为根据本发明一个实施例安装发射器后传感器电连接区防水结构的剖面结构示意 图；
图4为根据本发明一个实施例底壳带电池的俯视图；
图5a为根据本发明一个实施例电极电连接区的剖面结构示意图；
图5b为根据本发明一个实施例电极电连接区防水结构的剖面结构示意图；
图5c为根据本发明一个实施例安装发射器后电极电连接区防水结构的剖面结构示意图；
图6为根据本发明一个实施例连续葡萄糖监测装置的示意图。
具体实施方式
如前所述，现有技术的检测器件无法做到良好的防水效果，当用户进行沐浴、冲洗、游泳等水下活动时，水滴会进入到检测器件内，一旦与电连接区接触，会引起短路故障或者电流强度扰动，影响检测准确性和可靠性，因此用户往往在进行水下活动前，需要先将检测器件从身上取下，造成极大的不便。
为了解决该问题，本发明提供了一种体液分析物检测器件，在各电连接区设置防水结构，阻止水滴进入电连接区，避免引起短路和电流强度扰动，用户在进行沐浴、冲洗、游泳等水下动作时，无需将检测器从身上取下，增强了用户体验，提高了检测数据的可靠性。
现在将参照附图来详细描述本发明的各种示例性实施例。应理解，除非另外具体说明，否则在这些实施例中阐述的部件和步骤的相对布置、数字表达式和数值不应被理解为对本发明范围的限制。
此外，应当理解，为了便于描述，附图中所示出的各个部件的尺寸并不必然按照实际的比例关系绘制，例如某些单元的厚度、宽度、长度或距离可以相对于其他结构有所放大。
以下对示例性实施例的描述仅仅是说明性的，在任何意义上都不作为对本发明及其应用或使用的任何限制。这里对于相关领域普通技术人员已知的技术、方法和装置可能不作详细讨论，但在适用这些技术、方法和装置情况下，这些技术、方法和装置应当被视为本说明书的一部分。
应注意，相似的标号和字母在下面的附图中表示类似项，因此，一旦某一项在一个附图中被定义或说明，则在随后的附图说明中将不需要对其进行进一步讨论。
第一实施例
图1a为本发明实施例体液分析物检测器件的立体结构示意图。
检测器件包括底壳10、传感器11和发射器12。
底壳10用于装配发射器12和传感器11，并通过底部粘结胶布(图中未示出)将检测器件粘贴在皮肤表面。底壳10包括固定部与施力部。底壳10上设置有至少一个第二卡合 部101。第二卡合部101用于卡合发射器12。具体的，在本发明实施例中，第二卡合部101的数量为两个，两个第二卡合部101对应设置于底壳10的侧壁。
在这里，固定部与施力部是相对的概念。根据底壳10与发射器12的结构设计，固定部与施力部的位置可以有不同的选择，下文将详细叙述。
在本发明实施例中，两个第二卡合部101的连线l将底壳10分为A侧与B侧。A侧设置有施力部，B侧设置有固定部。
因此，在本发明实施例中，分离底壳10和发射器12的过程如下：用手指固定B侧的固定部，用另一个手指沿一个方向对施力部施加作用力F，使第二卡合部101失效，进而分离第二卡合部101与第一卡合部121，使发射器12与底壳10分离。
在本发明其他实施例中，第二卡合部101的数量为四个，四个第二卡合部101对应设置于底壳10相对的侧壁，每侧各两个。
在本发明其他实施例中，第二卡合部101的数量为六个，六个第二卡合部101对应设置于底壳10的侧壁，每侧各两个。
本发明的实施例对检测器件俯视图的形状并不作具体限制，其形状还可以为圆角矩形、矩形、圆形、椭圆形或者其它形状。
发射器12上设置有至少一个第一卡合部121。第一卡合部121与第二卡合部101相对应。通过第二卡合部101和第一卡合部121互相卡合，发射器12装配于底壳10上。明显的，在本发明实施例中，发射器12上设置有两个第一卡合部121，即，两对互相卡合的第一卡合部121与第二卡合部101。
在这里，第一卡合部121与第二卡合部101相对应是指两者的数量相等、位置对应。
当在分离底壳10与发射器12时，固定部被手指或者其他设备固定，利用另一个手指或者其他辅助设备在一个方向上对施力部施加力的作用，底壳10将失效，第二卡合部101和第一卡合部121互相分离，进而使发射器12与底壳10分离。即，用户在分离底壳10与发射器12时，仅用一根手指在一个方向对施力部施加作用力，就可将两者分离，便于用户操作。分离之后，发射器能够重复使用，降低了用户的成本。
在这里需要说明的是，失效为工程材料领域的常规概念。失效后，材料失去原有的功能作用，失效部位不能再次复原。由于第二卡合部101为底壳10的一部分，底壳10失效包括底壳10的底板、侧壁或者第二卡合部101失效。因此，底壳10的失效方式包括底壳10的底板或侧壁断裂、底壳10折损、第二卡合部101断裂、底壳10塑性形变中的一种或者多种。明显的，底壳10失效后，底壳10失去卡合发射器12的功能和作用。
固定固定部的方式包括夹持，支撑等方式，在这里并不作具体限制，只要能够满足将 固定部固定的条件即可。
结合图2所示传感器立体结构示意图，传感器11安装在底壳10上，至少包括探头113和导电胶条114，探头113用于刺入人体皮肤，检测体液分析物参数信息，并转换为电信号，电信号通过导电胶条114传递到发射器12的导电电极122，发射器12再向用户传输体液分析物参数信息。
在本发明实施例中，电池位于发射器12壳体内，形成良好的防水密封。导电电极122与导电胶条114形成电连接，在传感器底壳111上、导电胶条114四周设有凹槽131，用于放置密封环130，密封环轮廓与凹槽轮廓保持一致。
在本发明其他实施例中，密封环轮廓与凹槽轮廓也可以不一致，例如凹槽为方形、圆形、弧形或其组合形状，相应的密封环为圆形、弧形、方形或其组合形状。
为更清楚的理解凹槽131及密封环130组成的防水结构的防水原理，参照图3a、图3b、图3c。
图3a为安装密封环130前，图2所示传感器11的C-C’剖面图，凹槽131设置在传感器底壳111上，环绕在探头113和导电胶条114四周。探头113分为体内部分113b和体外部分113a，体外部分113a向底壳111上端弯折或者弯曲，并平铺在底壳111上。图3b为安装密封环131后，图2所示传感器11的C-C’剖面图，密封环130轮廓与凹槽131轮廓一致，密封环130紧密贴合凹槽131、探头13和导电胶条114，并且密封环130的上端面略高于导电胶条114的上端面。这里“略高”指密封环130上端面高于导电胶条114上端面0～5mm，优选为1mm。图3c为安装密封环131和发射器12后，图2所示传感器11的C-C’剖面图，导电电极122与导电胶条114接触，发射器壳体与密封环130上表面接触，可以预见的是发射器壳体12、密封环130和凹槽131可以形成密封的容室132，探头体外部分113a、导电胶条114和导电电极122位于该容室132内。当体液分析物检测器件进入水下时，水滴被发射器壳体12、密封环130和凹槽131阻挡，无法进入到容室132内，由此对导电电极122和导电胶条114的电连接区形成防水保护。
在本发明的其他实施例中，密封环尺寸略大于凹槽尺寸，这样可以使得密封环130更加紧密安装在凹槽131中，不易脱落，并且密封环130边缘可与凹槽131形成更密闭的接触，达到更理想的防水保护。
在本发明的其他实施例中，也可在探头体外部分113a下方、底壳111上方增设一层密封环(图中未示出)，与探头体外部分113a上方的密封环、凹槽共同组成防水结构，能更好的阻止水滴进入到电连接区，起到更好的防水效果。
在本发明的其他实施例中，密封环材料优选为绝缘橡胶，由于橡胶为柔性材料，且具 备一定的抗压弹性，发射器12安装到底壳10上时对密封环130有一定的挤压力，能更好的保持密封环130与发射器10壳体的紧密接触，阻止水滴进入电连接区，避免引起短路和电流强度扰动。在本发明实施例中，当底壳10将失效，第二卡合部101和第一卡合部121互相分离，密封环130的抗压弹性可以促使底壳10和发射器12分离。
第二实施例
图1b为发明另一个实施例体液分析物检测器件的结构示意图。
检测器件包括底壳20、传感器11和发射器22。
在本发明实施例中，固定部与施力部是相对的概念。根据底壳20与发射器22的结构设计，固定部与施力部的位置可以有不同的选择
在本发明实施例中，两个第二卡合部202的连线l 1将底壳20分为A侧与B侧。A侧设置有施力部，B侧设置有固定部。
因此，在本发明实施例中，分离底壳20和发射器22的过程如下：用手指固定B侧的固定部，用另一个手指沿一个方向对施力部施加作用力F，使第二卡合部202失效，进而分离第二卡合部202与第一卡合部221，使发射器22与底壳20分离。
在本发明实施例中，第二卡合部202的数量为两个，两个第二卡合部202对应设置于底壳10的侧壁。
在本发明其他实施例中，第二卡合部202的数量为四个，四个第二卡合部202对应设置于底壳10相对的侧壁，每侧各两个。
在本发明其他实施例中，第二卡合部202的数量为六个，六个第二卡合部202对应设置于底壳10的侧壁，每侧各两个。
本发明的实施例对检测器件俯视图的形状并不作具体限制，其形状还可以为圆角矩形、矩形、圆形、椭圆形或者其它形状。
本发明实施例的检测器件还包括电池208。电池208用于向发射器供电，并设置于底壳20内。底壳20中设置电池208的部位为电池密封腔室203。这样在每次更换底壳20时可以同时更换电池208，发射器22因不再设置电池而可以一直重复使用，减小了用户更换发射器22的成本，同时底壳20一直使用高性能的新电池，可以保证发射器22的持续高性能工作状态。
优选的，在本发明实施例中，电池密封腔室203的顶部与发射器22的顶部平齐，这样能够减小检测器件的厚度尺寸。
电池密封腔室203可直接作为施力部，因此，电池设置于l 1的A侧。由于电池密封腔室203较厚，面积相对较大，作为施力部，用户更容易将作用力施加在电池密封腔室203 上，优化用户的操作步骤。
图4为底壳20的俯视图。
由于电池208需要向发射器22供电，因此，在本发明实施例中，底壳20还设置有至少两个电极204。发射器22的电触点223通过电极204分别与电池的正负极电连接，形成电连接区。电池208通过电极204及电触点223向发射器供电，一旦电连接区进入水滴，导致短路，造成电池208供电不稳定，发射器22接收到的电流强度出现波动，可能导致发射器22接收到探头113的体液分析物参数信息以及发射的参数信息出现跳动，影响分析物检测器件的可靠性，因此需要对该电连接区进行防水保护。该电连接区防水结构包括凹槽207和密封环205。
在本发明其他实施例中，密封环轮廓与凹槽轮廓也可以不一致，例如凹槽为方形、圆形、弧形或其组合形状，相应的密封环为圆形、弧形、方形或其组合形状。
为更清楚的理解凹槽207及密封环205组成的防水结构的防水原理，参照图5a、图5b、图5c。
图5a为安装密封环205前，图4所示底壳20的D-D’剖面图，电池208放置在电池密封腔室203内，电池密封腔室203由电池208的正负极导电条209和底壳20的壳体构成，形成完全密闭空间，水滴无法进入电池密封腔室内，正负极导电条209持续向电池密封腔室203外延伸至凹槽207并覆盖凹槽207底端面，电极204位于凹槽207中间，一端固定于正负极导电条209上。图5b为安装密封环205后，图4所示底壳20的D-D’剖面图，密封环205位于凹槽207上端面，其轮廓与凹槽轮廓一致，并能包络住电极204，密封环205上端面略高于凹槽207上端面，这里“略高”指密封环205上端面高于凹槽207上端面0～5mm，优选为1mm。图5c为安装密封环205和发射器22后，图4所示底壳20的D-D’剖面图，发射器电源电极223与电极204接触，以获取电池208电能，发射器22的壳体与密封环205上表面接触，可以预见的是发射器22壳体、密封环205、凹槽207和正负极导电条209形成密封的容室210，发射器电源电极223、电极204位于该密封容室210内。当体液分析物检测器件进入水下时，水滴被发射器22壳体、密封环205和凹槽207阻挡，无法进入到容室210内，由此对发射器电源电极223、电极204、正负极导电条209的电连接区形成防水保护。
在本发明的其他实施例中，密封环尺寸略大于凹槽尺寸，这样可以使得密封环205更加紧密安装在凹槽207中，不易脱落，并且密封环205边缘可与凹槽207形成更密闭的接触，达到更理想的防水保护。
在本发明的其他实施例中，电极204为能够与发射器电源电极223电连接的弹性导电 材料，例如可以是导电弹簧或者导电弹片，发射器22安装在底壳20上时，发射器电源电极223挤压电极204，使电极204持续压缩并保持弹力，这样电极204可与发射器电源电极223保持持续的紧密接触，保证电池208为发射器22输送稳定的电能。
在本发明的其他实施例中，密封环材料优选为绝缘橡胶，由于橡胶为柔性材料，且具备一定的抗压弹性，发射器22安装到底壳20上时对密封环205有一定的挤压力，能更好的保持密封环205与发射器20壳体的紧密接触，阻止水滴进入电连接区，避免引起短路和电流强度扰动。
在本发明实施例中，传感器11与发射器22的导电电极222的防水结构与第一实施例相同，在此不再赘述。
在本发明实施例中，受到挤压的密封环105对发射器22施加一定的弹力，在对施力部施加作用力F时，密封环105提供促进发射器22与底壳20分离的弹力。
优选的，在本发明实施例中，为了密封发射器22与传感器的连接位置，传感器周围设置有密封环。与上述密封环105类似，当底壳20将失效，第二卡合部201和第一卡合部221互相分离，密封环130、205的抗压弹性可以促使底壳10和发射器12分离。
综上所述，本发明公开了一种体液分析物检测器件，在器件电连接区设置防水结构，阻止水滴进入电连接区，避免引起短路和电流强度扰动，用户在进行沐浴、冲洗、游泳等水下动作时，无需将检测器从身上取下，增强了用户体验，提高了检测数据的可靠性。
本发明还公开了一种连续葡萄糖监测装置，如图6所示，将传感器11安装到底壳10(20)上，后再将发射器12(22)安装到底壳20上后，发射器12(22)可以获取传感器11的检测数据指示信号，发射器12(22)再与接收器30无线数据连接，以向接收器30传输检测数据指示信号，供用户知晓检测数据。
虽然已经通过示例对本发明的一些特定实施例进行了详细说明，但是本领域的技术人员应该理解，以上示例仅是为了进行说明，而不是为了限制本发明的范围。本领域的技术人员应该理解，可在不脱离本发明的范围和精神的情况下，对以上实施例进行修改。本发明的范围由所附权利要求来限定。

Claims (18)

  1. 一种体液分析物检测器件，其特征在于，包括：
    发射器，所述发射器上设置有至少一个第一卡合部；
    底壳，所述底壳上设置有与所述第一卡合部相对应的第二卡合部，通过所述第一卡合部与所述第二卡合部互相卡合，所述发射器装配于所述底壳上，所述底壳包括固定部与施力部，在分离所述底壳与所述发射器时，固定所述固定部，并在一个方向上对所述施力部施加力的作用，所述底壳失效，至少一对互相卡合的所述第一卡合部与所述第二卡合部互相分离，进而分离所述底壳与所述发射器；
    安装至所述底壳上的传感器，包括探头和导电胶条，所述探头用于检测体液分析物参数信息，并通过所述导电胶条与所述发射器电连接，以传输参数信号；
    电池，与发射器电连接，用于为发射器提供电能；和
    防水结构，所述防水结构包括设置在所述底壳上的凹槽和密封环，所述密封环的下端面放置于凹槽内，上端面与所述发射器的壳体接触，用于为所述体液分析物检测器件的电连接区提供防水保护。
  2. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述电池密封在所述发射器内。
  3. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述电池密封在所述底壳内，形成电池密封腔室，并从所述电池密封腔室引出至少2个电极，所述电极至少包括1个正极和1个负极。
  4. 根据权利要求3所述的体液分析物检测器件，其特征在于，所述发射器与所述正极和所述负极分别电连接，以获取电池的电能。
  5. 根据权利要求4所述的体液分析物检测器件，其特征在于，所述防水结构分别位于所述发射器与所述正极、所述负极的电连接区。
  6. 根据权利要求2或5所述的体液分析物检测器件，其特征在于，所述防水结构还位于所述传感器与所述发射器的电连接区。
  7. 根据权利要求6所述的体液分析物检测装置，其特征在于，在对所述施力部施加作用力时，所述密封环提供促进所述底壳与所述发射器分离的弹力。
  8. 根据权利要求3～5任一所述的体液分析物检测器件，其特征在于，所述电极为弹性导电材料。
  9. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述密封环为绝缘橡胶环。
  10. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述密封环的直径大于所述凹槽的内径。
  11. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述密封环的上端面高于 所述凹槽的上端面。
  12. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述密封环有2个，分别位于所述探头的上、下侧。
  13. 根据权利要求1所述的体液分析物检测装置，其特征在于，所述底壳装配所述发射器的部分为所述施力部。
  14. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述底壳侧边设置有向外的凸部，所述凸部为所述施力部。
  15. 根据权利要求1所述的体液分析物检测装置，其特征在于，所述电池设置于所述底壳内，所述底壳中设置有至少一个连接孔，通过所述连接孔，所述发射器与所述电池的两极电连接，所述电池部位为所述施力部。
  16. 根据权利要求15所述的体液分析物检测装置，其特征在于，所述连接孔周围设置有密封圈以密封电连接位置，在对所述施力部施加作用力时，所述密封圈提供促进所述底壳与所述发射器分离的弹力。
  17. 根据权利要求1所述的体液分析物检测器件，其特征在于，所述底壳失效方式包括所述底壳的底板断裂、所述底壳折损、所述第二卡合部断裂、所述底壳变形中的一种或多种组合。
  18. 一种连续葡萄糖监测装置，包括接收器和如权利要求1所述的体液分析物检测器件，所述接收器用于接收所述发射器传输的参数信号。
PCT/CN2021/097188 2019-08-19 2021-05-31 体液分析物检测器件 Ceased WO2022028070A1 (zh)

Priority Applications (22)

Application Number Priority Date Filing Date Title
EP21854556.4A EP4190237A4 (en) 2019-08-19 2021-05-31 DEVICE FOR DETECTING ANALYTES OF BODY FLUIDS
US18/015,331 US20230210408A1 (en) 2019-08-19 2021-05-31 Body fluid analyte detection device and continuous glucose monitoring device
PCT/CN2021/136493 WO2022252548A1 (en) 2019-08-19 2021-12-08 Battery shell integrated analyte detection device
EP21943900.7A EP4346586A4 (en) 2021-05-31 2021-12-08 ANALYTE DETECTION DEVICE INTEGRATED IN A BATTERY CASE
US18/562,836 US20240225492A1 (en) 2019-08-19 2021-12-08 Battery shell integrated analyte detection device
US18/562,838 US20240266661A1 (en) 2021-05-31 2021-12-08 Battery shell integrated analyte detection device
PCT/CN2021/136533 WO2022252550A1 (en) 2019-08-19 2021-12-08 Highly integrated analyte detection device
EP21943902.3A EP4346588A4 (en) 2021-05-31 2021-12-08 HIGHLY INTEGRATED ANALYTE DETECTION DEVICE
PCT/CN2021/136506 WO2022252549A1 (en) 2019-08-19 2021-12-08 Battery shell integrated analyte detection device
EP21943901.5A EP4346587A4 (en) 2021-05-31 2021-12-08 Battery shell integrated analyte detection device
US18/562,842 US20240237926A1 (en) 2021-05-31 2021-12-08 Highly integrated analyte detection device
CN202111490401.6A CN115474932B (zh) 2019-08-19 2021-12-08 高集成型分析物检测器件
CN202111492198.6A CN115483489B (zh) 2019-08-19 2021-12-08 电池壳体一体化分析物检测器件
CN202111490408.8A CN115483485B (zh) 2019-08-19 2021-12-08 电池壳体一体化分析物检测器件
US18/562,337 US20240260862A1 (en) 2021-05-31 2021-12-30 Analyte detection device with circuit board and shell integration
CN202111651908.5A CN115475303A (zh) 2021-05-31 2021-12-30 电路壳体集成型分析物检测器件
CN202111656191.3A CN115475304A (zh) 2021-05-31 2021-12-30 电路壳体集成型分析物检测器件
EP21943957.7A EP4346589A4 (en) 2021-05-31 2021-12-30 ANALYTE DETECTION DEVICE WITH PRINTED CIRCUIT BOARD AND SHELL INTEGRATION
PCT/CN2021/143067 WO2022252605A1 (en) 2021-05-31 2021-12-30 Analyte detection device with circuit board and shell integration
PCT/CN2021/143074 WO2022252606A1 (en) 2021-05-31 2021-12-30 Analyte detection device with circuit board and shell integration
EP21943958.5A EP4346590A4 (en) 2021-05-31 2021-12-30 ANALYTE DETECTION DEVICE WITH CIRCUIT BOARD AND SHELL INTEGRATION
US18/562,840 US20240285193A1 (en) 2021-05-31 2021-12-30 Analyte detection device with circuit board and shell integration

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/CN2019/101271 WO2021031057A1 (en) 2019-08-19 2019-08-19 Sensing device
CNPCT/CN2020/106518 2020-08-03
PCT/CN2020/106522 WO2021164207A1 (en) 2019-08-19 2020-08-03 A body fluid analyte detection device
PCT/CN2020/106518 WO2021164206A1 (en) 2019-08-19 2020-08-03 A body fluid analyte detection device
CNPCT/CN2020/106522 2020-08-03

Publications (1)

Publication Number Publication Date
WO2022028070A1 true WO2022028070A1 (zh) 2022-02-10

Family

ID=74603809

Family Applications (18)

Application Number Title Priority Date Filing Date
PCT/CN2019/101271 Ceased WO2021031057A1 (en) 2019-08-19 2019-08-19 Sensing device
PCT/CN2020/075969 Ceased WO2021031542A1 (en) 2019-08-19 2020-02-20 Micro-analyte detection device
PCT/CN2020/075966 Ceased WO2021031541A1 (en) 2019-08-19 2020-02-20 Highly integrated analyte detection device
PCT/CN2020/079802 Ceased WO2021164085A1 (en) 2019-08-19 2020-03-18 A mounting unit of an analyte detection device and a mounting method thereof
PCT/CN2020/100601 Ceased WO2021164184A1 (en) 2019-08-19 2020-07-07 Highly integrated intelligent analyte detection device
PCT/CN2020/100599 Ceased WO2021164183A1 (en) 2019-08-19 2020-07-07 Intelligent detention device
PCT/CN2020/100604 Ceased WO2021164185A1 (en) 2019-08-19 2020-07-07 Highly integrated analyte detection device
PCT/CN2020/106518 Ceased WO2021164206A1 (en) 2019-08-19 2020-08-03 A body fluid analyte detection device
PCT/CN2020/106522 Ceased WO2021164207A1 (en) 2019-08-19 2020-08-03 A body fluid analyte detection device
PCT/CN2020/120776 Ceased WO2021164278A1 (en) 2019-08-19 2020-10-14 Analyte detection device with intelligent identification function
PCT/CN2021/097188 Ceased WO2022028070A1 (zh) 2019-08-19 2021-05-31 体液分析物检测器件
PCT/CN2021/097173 Ceased WO2022012187A1 (zh) 2019-08-19 2021-05-31 高可靠性分析物检测器件
PCT/CN2021/105107 Ceased WO2022012400A1 (en) 2019-08-19 2021-07-08 Highly integrated analyte detection device
PCT/CN2021/136493 Ceased WO2022252548A1 (en) 2019-08-19 2021-12-08 Battery shell integrated analyte detection device
PCT/CN2021/136506 Ceased WO2022252549A1 (en) 2019-08-19 2021-12-08 Battery shell integrated analyte detection device
PCT/CN2021/136533 Ceased WO2022252550A1 (en) 2019-08-19 2021-12-08 Highly integrated analyte detection device
PCT/CN2022/080845 Ceased WO2022252744A1 (en) 2019-08-19 2022-03-15 Analyte detection device
PCT/CN2022/110056 Ceased WO2023173654A1 (en) 2019-08-19 2022-08-03 Highly integrated drug infusion device

Family Applications Before (10)

Application Number Title Priority Date Filing Date
PCT/CN2019/101271 Ceased WO2021031057A1 (en) 2019-08-19 2019-08-19 Sensing device
PCT/CN2020/075969 Ceased WO2021031542A1 (en) 2019-08-19 2020-02-20 Micro-analyte detection device
PCT/CN2020/075966 Ceased WO2021031541A1 (en) 2019-08-19 2020-02-20 Highly integrated analyte detection device
PCT/CN2020/079802 Ceased WO2021164085A1 (en) 2019-08-19 2020-03-18 A mounting unit of an analyte detection device and a mounting method thereof
PCT/CN2020/100601 Ceased WO2021164184A1 (en) 2019-08-19 2020-07-07 Highly integrated intelligent analyte detection device
PCT/CN2020/100599 Ceased WO2021164183A1 (en) 2019-08-19 2020-07-07 Intelligent detention device
PCT/CN2020/100604 Ceased WO2021164185A1 (en) 2019-08-19 2020-07-07 Highly integrated analyte detection device
PCT/CN2020/106518 Ceased WO2021164206A1 (en) 2019-08-19 2020-08-03 A body fluid analyte detection device
PCT/CN2020/106522 Ceased WO2021164207A1 (en) 2019-08-19 2020-08-03 A body fluid analyte detection device
PCT/CN2020/120776 Ceased WO2021164278A1 (en) 2019-08-19 2020-10-14 Analyte detection device with intelligent identification function

Family Applications After (7)

Application Number Title Priority Date Filing Date
PCT/CN2021/097173 Ceased WO2022012187A1 (zh) 2019-08-19 2021-05-31 高可靠性分析物检测器件
PCT/CN2021/105107 Ceased WO2022012400A1 (en) 2019-08-19 2021-07-08 Highly integrated analyte detection device
PCT/CN2021/136493 Ceased WO2022252548A1 (en) 2019-08-19 2021-12-08 Battery shell integrated analyte detection device
PCT/CN2021/136506 Ceased WO2022252549A1 (en) 2019-08-19 2021-12-08 Battery shell integrated analyte detection device
PCT/CN2021/136533 Ceased WO2022252550A1 (en) 2019-08-19 2021-12-08 Highly integrated analyte detection device
PCT/CN2022/080845 Ceased WO2022252744A1 (en) 2019-08-19 2022-03-15 Analyte detection device
PCT/CN2022/110056 Ceased WO2023173654A1 (en) 2019-08-19 2022-08-03 Highly integrated drug infusion device

Country Status (5)

Country Link
US (12) US20220218240A1 (zh)
EP (11) EP4017357A4 (zh)
CN (16) CN112386251B (zh)
ES (1) ES3058746T3 (zh)
WO (18) WO2021031057A1 (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021031057A1 (en) * 2019-08-19 2021-02-25 Medtrum Technologies Inc. Sensing device
EP4093460A4 (en) * 2020-01-21 2023-09-27 Medtrum Technologies Inc. Medical device with safety verification and safety verification method thereof
US20230173492A1 (en) * 2020-05-29 2023-06-08 Hewlett-Packard Development Company, L.P. Consumable microfluidic device
ES3069612T3 (en) * 2020-07-15 2026-06-09 Medtrum Tech Inc High-reliability analyte detection device
EP4346588A4 (en) * 2021-05-31 2024-10-30 Medtrum Technologies Inc. HIGHLY INTEGRATED ANALYTE DETECTION DEVICE
CN115474931B (zh) * 2021-05-31 2025-10-31 上海移宇科技股份有限公司 体液分析物检测器件
WO2022252002A1 (zh) * 2021-05-31 2022-12-08 上海移宇科技股份有限公司 体液分析物检测器件
EP4346586A4 (en) * 2021-05-31 2024-10-30 Medtrum Technologies Inc. ANALYTE DETECTION DEVICE INTEGRATED IN A BATTERY CASE
CN115704820B (zh) * 2021-08-06 2025-08-05 上海移宇科技股份有限公司 体液分析物检测器件
CN115886803B (zh) * 2021-08-18 2025-11-25 上海移宇科技股份有限公司 智能检测装置
WO2023019453A1 (en) * 2021-08-18 2023-02-23 Medtrum Technologies Inc. Intelligent detection device
EP4408280B1 (en) * 2021-09-27 2026-07-22 Medtrum Technologies Inc. Installation unit of analyte detection device
US20240389890A1 (en) * 2021-09-27 2024-11-28 Medtrum Technologies Inc. Analyte detection system
WO2023102778A1 (en) * 2021-12-08 2023-06-15 Medtrum Technologies Inc. Positive electrode plate for medical device battery and its preparation method
CN114886422A (zh) * 2022-05-20 2022-08-12 湖州美奇医疗器械有限公司 一种传感器和发射器的卡合结构
US12594031B2 (en) * 2022-06-03 2026-04-07 Oura Health Oy Detachable battery in a wearable ring device
CN114711765B (zh) * 2022-06-07 2022-10-14 苏州百孝医疗科技有限公司 连续分析物浓度监测系统
CN117617965A (zh) * 2024-01-16 2024-03-01 上海移宇科技有限公司 分析物检测器件
WO2025152017A1 (zh) * 2024-01-16 2025-07-24 上海移宇科技有限公司 体液分析物检测器件
WO2025152020A1 (zh) * 2024-01-16 2025-07-24 上海移宇科技有限公司 分析物检测系统
CN122070090A (zh) * 2024-01-16 2026-05-19 上海移宇科技有限公司 体液分析物检测器件
WO2025152018A1 (zh) * 2024-01-16 2025-07-24 上海移宇科技有限公司 紧凑型体液分析物检测器件

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202266572U (zh) * 2011-09-21 2012-06-06 深圳市理邦精密仪器股份有限公司 一种密封装配结构
EP2332466B1 (en) * 2004-07-13 2014-04-09 DexCom, Inc. Transcutaneous analyte sensor
CN106470593A (zh) * 2014-02-24 2017-03-01 美多尼克监测公司 可分离式监测装置和方法
CN110584676A (zh) * 2019-08-19 2019-12-20 上海移宇科技股份有限公司 传感装置
CN210204726U (zh) * 2019-01-31 2020-03-31 青岛光电医疗科技有限公司 一次性防水型心电电极及移动式心电监测设备
CN112394097A (zh) * 2019-08-19 2021-02-23 上海移宇科技股份有限公司 微型分析物检测装置

Family Cites Families (194)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4449774A (en) * 1981-02-05 1984-05-22 Shin-Etsu Polymer Co., Ltd. Electroconductive rubbery member and elastic connector therewith
GB8414036D0 (en) * 1984-06-01 1984-07-04 Emi Ltd Field effect devices
WO1988009643A1 (fr) * 1987-06-13 1988-12-15 Tdk Corporation Electrode terminale etanche a l'eau pour corps vivants
EP0443073A1 (en) * 1990-02-23 1991-08-28 Kabushiki Kaisha Fine Rubber Kenkyuusho Pressure sensor utilizing extension type conductive rubber
FR2675124A1 (fr) * 1991-04-15 1992-10-16 Sincoplas Boite d'emballage perdu destinee notamment a contenir une recharge de produit cosmetique.
JPH05205531A (ja) * 1992-01-27 1993-08-13 Nitto Denko Corp 異方性導電膜及びその製造方法
US8974386B2 (en) * 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) * 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8688188B2 (en) * 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US7113069B1 (en) * 1999-11-30 2006-09-26 Smiths Detection Inc. Aligned particle based sensor elements
JP2001281197A (ja) * 2000-03-30 2001-10-10 Matsushita Electric Ind Co Ltd バイオセンサ測定装置
EP1466007A1 (en) * 2001-12-17 2004-10-13 Powderject Research Limited Non-or minimally invasive monitoring methods
CN2542206Y (zh) * 2002-06-03 2003-04-02 古鹏飞 破坏型一次性安全自动采血针
US20140121989A1 (en) * 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
JP4530333B2 (ja) * 2003-11-14 2010-08-25 日立マクセル株式会社 密閉型電池
US9247900B2 (en) * 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
JP2005251654A (ja) * 2004-03-05 2005-09-15 Jst Mfg Co Ltd 異方導電性シート及びその製造方法
US8277713B2 (en) * 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US8792955B2 (en) * 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US7905833B2 (en) * 2004-07-13 2011-03-15 Dexcom, Inc. Transcutaneous analyte sensor
US7946984B2 (en) * 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
ES2334671T3 (es) * 2004-08-13 2010-03-15 Egomedical Technologies Ag Sistema de ensayo de analitos para determinar la concentracion de un analito en un fluido fisiologico o acuoso.
CN101091114A (zh) * 2004-08-31 2007-12-19 生命扫描苏格兰有限公司 制造自动校准传感器的方法
US7418285B2 (en) * 2004-12-29 2008-08-26 Abbott Laboratories Analyte test sensor and method of manufacturing the same
US20090105569A1 (en) * 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
DE202005002650U1 (de) * 2005-02-18 2005-08-11 TaiDoc Technology Corp., Ltd., San-Chung Intelligentes Biosensormessgerät
US20090076360A1 (en) * 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US9072476B2 (en) * 2005-09-23 2015-07-07 Medtronic Minimed, Inc. Flexible sensor apparatus
ATE433711T1 (de) * 2005-12-19 2009-07-15 Hoffmann La Roche Sandwichsensor zur ermittlung einer analytkonzentration
RU2008130871A (ru) * 2005-12-27 2010-02-10 Байер Хелткэр Ллк (Us) Способ создания автокалибровочных контуров для тестовых датчиков с нанесением покрытия методом химического восстановления
JP2007281013A (ja) * 2006-04-03 2007-10-25 Seiko Epson Corp 半導体装置
JP2006318923A (ja) * 2006-06-16 2006-11-24 Jsr Corp 導電性ゴムシートならびにそれを用いたコネクターおよび回路基板の電気的検査用冶具、ならびに導電性ゴムシートの製造方法
US9119582B2 (en) * 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
US7918121B2 (en) * 2006-08-14 2011-04-05 Bayer Healthcare, Llc Meter system designed to run singulated test sensors
CN101563022B (zh) * 2006-12-22 2012-05-30 梅丁格有限公司 带体内电化学分析物感测的流体传输
JP2010522012A (ja) * 2007-03-19 2010-07-01 インスライン メディカル エルティーディー． 薬物送達のための方法及びデバイス
EP1987761B1 (de) * 2007-05-03 2019-10-23 F. Hoffmann-La Roche AG Schlauchförmiger Sensor zum Nachweis eines Analyten
US20100324398A1 (en) * 2007-05-11 2010-12-23 Jung Tzyy-Ping Non-invasive characterization of a physiological parameter
WO2009060432A1 (en) * 2007-11-07 2009-05-14 Medingo Ltd. Device and method for preventing diabetic complications
DK2224977T3 (en) * 2007-11-21 2017-08-14 Hoffmann La Roche ANALYSIS MONITORING AND FLUID DISTRIBUTION SYSTEM
CA2718265C (en) * 2008-03-17 2017-08-29 Isense Corporation Analyte sensor subassembly and methods and apparatuses for inserting an analyte sensor associated with same
US8396528B2 (en) * 2008-03-25 2013-03-12 Dexcom, Inc. Analyte sensor
JP4919093B2 (ja) * 2008-03-31 2012-04-18 Ｊｓｒ株式会社 異方導電性シート
WO2010019485A2 (en) * 2008-08-14 2010-02-18 Balan Biomedical, Inc. High energy density battery for use in implantable medical devices and methods of manufacture
WO2010032484A1 (ja) * 2008-09-22 2010-03-25 パナソニック株式会社 携帯電子機器
WO2010064998A1 (en) * 2008-12-04 2010-06-10 Venture Corporation Limited A lancing device
US20100198034A1 (en) * 2009-02-03 2010-08-05 Abbott Diabetes Care Inc. Compact On-Body Physiological Monitoring Devices and Methods Thereof
WO2010098067A1 (ja) * 2009-02-24 2010-09-02 パナソニック株式会社 電池モジュールとそれを用いた電池モジュール集合体
TW201031384A (en) * 2009-02-25 2010-09-01 Micro Star Int Co Ltd A portable physiological information measurement device
CN104825171B (zh) * 2009-02-26 2017-08-04 雅培糖尿病护理公司 改进的分析物传感器及其制造和使用方法
US20100277119A1 (en) * 2009-05-01 2010-11-04 Medtronic Minimed, Inc. Medical Device Charging System
US8970384B2 (en) * 2009-06-14 2015-03-03 Roche Diagnostics Operations, Inc. Devices and methods for malfunctions recognition in a therapeutic dispensing device
CN201522508U (zh) * 2009-11-13 2010-07-07 沁业科技有限公司 矩阵列式导接模块
HUE054269T2 (hu) * 2010-01-28 2021-08-30 Hoffmann La Roche Moduláris infúziós készlet integrált, elektromosan mûködtetett funkcionális alkatrésszel
US10448872B2 (en) * 2010-03-16 2019-10-22 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US20110256024A1 (en) * 2010-04-16 2011-10-20 Abbott Diabetes Care Inc. Modular Analyte Monitoring Device
JP2013524888A (ja) * 2010-04-16 2013-06-20 アボット ダイアベティス ケア インコーポレイテッド アナライト監視装置および方法
WO2011141753A1 (en) * 2010-05-13 2011-11-17 Aircraft Medical Limited Electrical device power management
EP2400292A1 (de) * 2010-06-24 2011-12-28 Roche Diagnostics GmbH System zur Messung einer Analytkonzentration einer Körperflüssigkeitsprobe
ES2708093T3 (es) * 2010-08-27 2019-04-08 Hoffmann La Roche Dispositivo y procedimiento para realizar al menos una función médica
US8507119B2 (en) * 2010-09-17 2013-08-13 Panasonic Corporation Battery block and battery module
CN107961016B (zh) * 2010-12-09 2021-06-15 雅培糖尿病护理股份有限公司 具有包括小型感测斑点的感测表面的分析物传感器
CN103687535B (zh) * 2011-06-17 2017-03-22 雅培糖尿病护理股份有限公司 实现分析物传感器与其它装置之间的连接的连接器
US20130060106A1 (en) * 2011-09-06 2013-03-07 Medtronic Minimed, Inc. Optical sensing systems and methods
EP2754392B1 (en) * 2011-09-09 2021-01-06 Terumo Kabushiki Kaisha Sensor insertion device
CN102579054B (zh) * 2012-03-06 2014-07-16 北京超思电子技术股份有限公司 一种防水壳体及血氧测量仪
US9451912B2 (en) * 2012-03-13 2016-09-27 Terumo Kabushiki Kaisha Sensor insertion device and method for operating said device
US9931065B2 (en) * 2012-04-04 2018-04-03 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
US9493807B2 (en) * 2012-05-25 2016-11-15 Medtronic Minimed, Inc. Foldover sensors and methods for making and using them
EP2668902A1 (en) * 2012-05-31 2013-12-04 Roche Diagniostics GmbH Sensor cartridge and inserter
EP2880432A4 (en) * 2012-08-05 2016-03-02 Univ Ramot PLACEABLE SENSOR AND METHOD FOR ITS USE
CN104582570B (zh) * 2012-09-24 2016-12-21 泰尔茂株式会社 传感器插入装置
JP6112338B2 (ja) * 2012-10-24 2017-04-12 トヨタ自動車株式会社 二次電池
US9344777B2 (en) * 2012-12-20 2016-05-17 Abbott Diabetes Care Inc. Wireless communication authentication for medical monitoring device
US10426383B2 (en) * 2013-01-22 2019-10-01 Medtronic Minimed, Inc. Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating
GB2510600B (en) * 2013-02-08 2015-05-20 R & D Core Ltd Calibration of Contact Sensor
KR20140123007A (ko) * 2013-04-11 2014-10-21 주식회사 엘지화학 라운드 코너를 포함하는 전지셀
CN105393108A (zh) * 2013-04-30 2016-03-09 成都领御生物技术有限公司 量子点免疫层析试条检测系统及其应用
US10213141B2 (en) * 2013-04-30 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for energy efficient electrical device activation
CN203707529U (zh) * 2013-07-09 2014-07-09 古河电气工业株式会社 旋转连接器
CN103367797A (zh) * 2013-07-23 2013-10-23 耀安电池电源科技（深圳）有限公司 可充电的纽扣式锂离子电池及其制造方法
CN103462615B (zh) * 2013-09-13 2015-12-16 上海移宇科技有限公司 微米尺度葡萄糖传感器微电极
CN203576512U (zh) * 2013-11-04 2014-05-07 理康互联科技(北京)有限公司 分析物传感装置
EP2899791B1 (en) * 2013-11-27 2018-08-01 LG Chem, Ltd. Electrode assembly and electrochemical device including same
KR101519742B1 (ko) * 2013-11-28 2015-05-12 율촌화학 주식회사 내충격성 및 안정성을 갖는 셀 파우치 및 그 제조방법
CN103750819B (zh) * 2013-12-25 2016-08-31 浙江凯立特医疗器械有限公司 可控制植入角度的皮下组织内传感器装置
CN103750818B (zh) * 2013-12-25 2016-03-30 浙江凯立特医疗器械有限公司 用于植入式生物传感器的快速植入器
CN104749228B (zh) * 2013-12-30 2018-07-06 深圳先进技术研究院 同时检测血糖和血脂的试纸条及方法
CN104739444B (zh) * 2013-12-31 2018-04-27 深圳迈瑞生物医疗电子股份有限公司 超声探头及含有该超声探头的超声检测装置
US20150238118A1 (en) * 2014-02-27 2015-08-27 Biorasis, Inc. Detection of the spatial location of an implantable biosensing platform and method thereof
CN104887242B (zh) * 2014-03-07 2018-08-28 上海移宇科技股份有限公司 分析物传感系统
JP6629232B2 (ja) * 2014-04-11 2020-01-15 アセンシア・ディアベティス・ケア・ホールディングス・アーゲー バッテリで動作するバイオセンサメータのための無線送信機アダプタおよびその提供方法
WO2016009251A1 (en) * 2014-07-15 2016-01-21 Comftech S.R.L. Sensor for measurement of physiological electrical signals
US10335066B2 (en) * 2014-09-03 2019-07-02 Nova Biomedical Corporation Subcutaneous sensor inserter and method
US9872633B2 (en) * 2014-09-29 2018-01-23 Becton, Dickinson And Company Cannula insertion detection
US10119993B2 (en) * 2014-10-30 2018-11-06 Tongfu Microelectronics Co., Ltd. Testing probe and semiconductor testing fixture, and fabrication methods thereof
CN105651980A (zh) * 2014-11-14 2016-06-08 厚美德生物科技股份有限公司 具有一体成型顶盖的生化数值检测仪
US10251605B2 (en) * 2015-02-16 2019-04-09 Verily Life Sciences Llc Bandage type of continuous glucose monitoring system
WO2016133841A1 (en) * 2015-02-16 2016-08-25 Verily Life Sciences Llc Electrochemical sensor for a bandage type of continuous glucose monitoring system
US9985255B2 (en) * 2015-03-05 2018-05-29 Medtronic, Inc. Battery encasement for implantable devices
CN204542144U (zh) * 2015-03-12 2015-08-12 深圳市光聚通讯技术开发有限公司 微型动态血糖仪
KR101848417B1 (ko) * 2015-04-27 2018-04-12 주식회사 아모그린텍 웨어러블 장치
CN204606554U (zh) * 2015-05-09 2015-09-02 杜启明 一种基于一次性卡扣的安全箱袋
US9839382B2 (en) * 2015-05-18 2017-12-12 Pacesetter, Inc. Device and method for sensing blood glucose
CN204833208U (zh) * 2015-07-28 2015-12-02 南昌欧菲光科技有限公司 触控产品及其电连接装置
CN105615841A (zh) * 2015-10-08 2016-06-01 上海温尔信息科技有限公司 连接器及温度计探头、温度计主体和防水型分体式温度计
CN112932477A (zh) * 2015-10-19 2021-06-11 中国农业大学 植于活鱼眼球巩膜组织间液内的血糖传感器及制备方法
CN120938426A (zh) * 2015-10-21 2025-11-14 德克斯康公司 经皮分析物传感器、其施加器以及相关联方法
EP3170453B1 (en) * 2015-11-19 2021-03-17 Roche Diabetes Care GmbH Sensor assembly for detecting at least one analyte in a body fluid and method of assembling a sensor assembly
EP3610791A1 (en) * 2015-11-19 2020-02-19 Roche Diabetes Care GmbH Sensor and sensor assembly for detecting an analyte in a body fluid
JP2017118911A (ja) * 2015-12-28 2017-07-06 セイコーエプソン株式会社 センサー基板、分析素子、グルコース測定装置およびインスリン供給装置
WO2017117416A1 (en) * 2015-12-30 2017-07-06 Dexcom, Inc. System and method for factory calibration or reduced calibration of an indwelling sensor based on sensitivity profile
EP3397142B1 (en) * 2015-12-30 2020-09-23 Dexcom, Inc. Transcutaneous analyte sensor systems
US10436773B2 (en) * 2016-01-18 2019-10-08 Jana Care, Inc. Mobile device based multi-analyte testing analyzer for use in medical diagnostic monitoring and screening
ES2961001T3 (es) * 2016-01-19 2024-03-07 Hoffmann La Roche Conjunto de sensor y procedimiento para detectar al menos un analito en un líquido corporal
EP3203396A1 (en) * 2016-02-02 2017-08-09 Roche Diabetes Care GmbH System and method for analyzing glucose monitoring data indicative of a glucose level, and a computer program product
PL4233721T3 (pl) * 2016-02-05 2024-10-21 F. Hoffmann-La Roche Ag Urządzenie medyczne do wykrywania co najmniej jednego analitu w płynie ustrojowym
ITUA20161342A1 (it) * 2016-03-04 2017-09-04 Eltek Spa Dispositivo sensore per contenitori di sostanze liquide
ITUA20161345A1 (it) * 2016-03-04 2017-09-04 Eltek Spa Dispositivo sensore per contenitori di sostanze liquide
US20170290535A1 (en) * 2016-04-08 2017-10-12 Medtronic Minimed, Inc. Analyte sensor with indicators
US10765369B2 (en) * 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Analyte sensor
US10765348B2 (en) * 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Sensor and transmitter product
US10420508B2 (en) * 2016-04-08 2019-09-24 Medtronic Minimed, Inc. Sensor connections
JP6462186B2 (ja) * 2016-04-27 2019-01-30 Ｐｈｃホールディングス株式会社 センサ挿入装置
US20170325725A1 (en) * 2016-05-13 2017-11-16 Percusense, LLC Vivo sensing and infusion devices
CN106025366A (zh) * 2016-07-13 2016-10-12 深圳市秸川材料科技有限公司 一种锂离子纽扣电池
EP3278729B1 (en) 2016-08-04 2020-06-24 Roche Diabetes Care GmbH Medical device for detecting at least one analyte in a body fluid
CN106137214A (zh) * 2016-08-12 2016-11-23 上海移宇科技股份有限公司 一种经皮分析物传感设备及其安装方法
WO2018027940A1 (en) * 2016-08-12 2018-02-15 Medtrum Technologies Inc. Transcutaneous analyte sensing system and methods of installation thereof
KR102589016B1 (ko) * 2016-08-25 2023-10-16 삼성전자주식회사 반도체 소자
JP6738247B2 (ja) * 2016-09-08 2020-08-12 Ykk Ap株式会社 開閉制御装置及び建具
WO2018057318A1 (en) * 2016-09-21 2018-03-29 Cardiac Pacemakers, Inc. Leadless stimulation device with a housing that houses internal components of the leadless stimulation device and functions as the battery case and a terminal of an internal battery
KR102588428B1 (ko) * 2016-10-10 2023-10-12 삼성전자주식회사 안테나 장치 및 그것을 포함하는 전자 장치
US20180115017A1 (en) * 2016-10-20 2018-04-26 Johnson & Johnson Vision Care, Inc. Biomedical energization elements with polymer electrolytes
US11462320B2 (en) * 2016-11-09 2022-10-04 Dexcom, Inc. Systems and methods for technical support of continuous analyte monitoring and sensor systems
CN108078569B (zh) * 2016-11-21 2024-06-25 南通九诺医疗科技有限公司 一种手机app直接监控的动态血糖监测仪及其控制方法
CN108078570B (zh) * 2016-11-21 2024-06-25 南通九诺医疗科技有限公司 一种内置加速度传感器的动态血糖监测电路及其控制方法
CN206576873U (zh) * 2016-11-21 2017-10-24 南通九诺医疗科技有限公司 一种手机app直接监控的动态血糖监测仪
CN110177501B (zh) * 2016-12-22 2022-04-29 圣维塔医疗公司 持续葡萄糖监测系统及方法
CA3139635A1 (en) * 2016-12-27 2018-07-05 Dexcom, Inc. Systems and methods for patient monitoring using an hcp-specific device
CN108281200A (zh) * 2016-12-30 2018-07-13 上海移宇科技股份有限公司 一种在动态血糖监测系统中调整算法的方法及应用该方法的动态血糖监测系统
CN106949988A (zh) * 2017-03-13 2017-07-14 泉州市小新智能科技有限公司 一种纽扣式温感器及其工作方法
HUE071675T2 (hu) * 2017-03-21 2025-09-28 Hoffmann La Roche Orvostechnikai eszköz és eljárás annak gyártására
CN207662531U (zh) * 2017-04-21 2018-07-27 深圳市爱立康医疗股份有限公司 一种体温计
CN206772463U (zh) * 2017-04-21 2017-12-19 深圳市爱立康医疗股份有限公司 一种超薄体温计
EP3406193B1 (en) * 2017-05-23 2021-12-08 Roche Diabetes Care GmbH Sensor system and method for manufacturing thereof
CN207898483U (zh) * 2017-05-27 2018-09-25 北京怡唐生物科技有限公司 动态连续血糖监测系统的一次性监测装置信号发送器
CN107014877B (zh) * 2017-05-27 2023-06-20 北京怡唐生物科技有限公司 一种动态连续血糖监测系统
JP7562259B2 (ja) 2017-06-19 2024-10-07 デックスコム・インコーポレーテッド 経皮的分析物センサを適用するためのアプリケータ、および関連した製造方法
JP7532036B2 (ja) * 2017-06-23 2024-08-13 デックスコム・インコーポレーテッド 経皮分析物センサ、そのためのアプリケータ、および関連した方法
MX2019014579A (es) * 2017-06-24 2020-02-07 Nxstage Medical Inc Sistemas, dispositivos y metodos de manejo y medicion de fluidos.
CN107361775A (zh) 2017-07-24 2017-11-21 湖州美奇医疗器械有限公司 一种血糖仪
CN111246797B (zh) * 2017-10-24 2025-09-09 德克斯康公司 预连接分析物传感器
TWI640296B (zh) 2017-12-12 2018-11-11 研能科技股份有限公司 血糖偵測裝置
JP7413279B2 (ja) * 2018-05-03 2024-01-15 デックスコム・インコーポレーテッド 自動分析物センサ較正および誤差検出のための方法
WO2019213608A1 (en) * 2018-05-04 2019-11-07 Dexcom, Inc. Systems and methods relating to an analyte sensor system having a battery located within a disposable base
CN208142255U (zh) * 2018-05-21 2018-11-23 青岛迈金智能科技有限公司 一种心率检测模块及心率带
CN109085329A (zh) * 2018-07-23 2018-12-25 青岛厚美德生物科技有限公司 一种免调码生物传感试纸及其免调码识别处理方法
KR102200138B1 (ko) * 2018-07-31 2021-01-11 주식회사 아이센스 연속 혈당 측정 장치
CN109199400B (zh) * 2018-09-10 2021-08-31 中山大学 基于微针阵列的血糖电化学传感器
US11239668B2 (en) * 2018-09-21 2022-02-01 Google Llc Charger case for wearable electronics
CN109148786A (zh) * 2018-10-18 2019-01-04 天津中聚新能源科技有限公司 一种具有灭火防护功能的电池
CN109350079A (zh) * 2018-11-14 2019-02-19 贝生(广州)传感科技有限公司 一种持续葡萄糖监测系统的植入装置
US20200194749A1 (en) * 2018-12-14 2020-06-18 TeraWatt Technolgy Inc. Prelithiated anode in battery cells for electric vehicles
CN109730674B (zh) * 2019-01-31 2024-04-30 青岛光电医疗科技有限公司 一次性防水型心电电极及移动式心电监测设备
US20200330009A1 (en) * 2019-04-22 2020-10-22 Dexcom, Inc. Preconnected analyte sensors
CN210541578U (zh) * 2019-04-30 2020-05-19 三诺生物传感股份有限公司 一种新型动态血糖监测仪发射器和动态血糖监测仪
CN109998560B (zh) * 2019-04-30 2023-12-22 苏州百孝医疗科技有限公司 分离供电动态血糖监测发射器、系统及信号采样方法
CN210056040U (zh) * 2019-04-30 2020-02-14 苏州百孝医疗科技有限公司 分离供电动态血糖监测发射器及其系统
CN109998555B (zh) 2019-04-30 2023-12-15 苏州百孝医疗科技有限公司 一种受体生理参数测量系统
TWI699189B (zh) * 2019-05-29 2020-07-21 華廣生技股份有限公司 生物感測裝置及生物感測裝置啟動方法
CN110370738A (zh) * 2019-06-28 2019-10-25 佛山佛塑科技集团股份有限公司 一种锂离子电池用软包装膜
WO2021012075A1 (en) * 2019-07-19 2021-01-28 Medtrum Technologies Inc. Integrated drug infusion device
CN112237658B (zh) * 2019-07-19 2022-10-04 上海移宇科技股份有限公司 集成型药物输注装置
CN112294257B (zh) * 2019-08-02 2024-08-20 华广生技股份有限公司 生理讯号传感装置
CN211014024U (zh) 2019-08-02 2020-07-14 普乐药业有限公司 便携式血糖测量仪
CN110296970A (zh) 2019-08-02 2019-10-01 普乐药业有限公司 便携式血糖测量仪
CN110680343A (zh) * 2019-09-11 2020-01-14 杭州瀚科医疗科技有限公司 新型皮下葡萄糖传感器电路导通方法
CN110722863B (zh) * 2019-10-15 2021-10-08 界首市天鸿新材料股份有限公司 一种锂电池用耐腐蚀软包装膜制备方法
US12303261B2 (en) * 2019-11-08 2025-05-20 Ascensia Diabetes Care Holdings Ag Devices, systems, and methods for measuring analytes in interstitial fluid
CN110881983B (zh) * 2019-11-20 2025-05-06 浙江大学 一种柔性微创血糖传感器
CN211749634U (zh) * 2019-12-03 2020-10-27 华东数字医学工程研究院 分析物传感器模块和分析物传感器系统
CN210868333U (zh) * 2019-12-03 2020-06-26 华东数字医学工程研究院 分析物传感系统
EP3851038A1 (en) * 2020-01-14 2021-07-21 Bionime Corporation Charging device for physiological signal sensor
US12471810B2 (en) * 2020-02-20 2025-11-18 Medtrum Technologies Inc. Highly integrated analyte detection device
CN111244381A (zh) * 2020-03-05 2020-06-05 清华大学 一种全极耳型纽扣电池及其制造方法
WO2021177906A1 (en) * 2020-03-06 2021-09-10 Chulalongkorn University A non-invasive wearable sensor device for detecting biomarkers in secretion
EP4164489A4 (en) * 2020-06-10 2024-06-19 Zense-Life Inc. GAS STERILIZED CONTINUOUS METABOLIC MONITORING DEVICE
ES3069612T3 (en) * 2020-07-15 2026-06-09 Medtrum Tech Inc High-reliability analyte detection device
US12082924B2 (en) * 2020-07-31 2024-09-10 Medtronic Minimed, Inc. Sensor identification and integrity check design
CN112120709A (zh) * 2020-09-27 2020-12-25 微泰医疗器械(杭州)有限公司 一种血糖监测装置
CN214632156U (zh) * 2020-11-27 2021-11-09 浙江凯立特医疗器械有限公司 一种可充电式发射器
CN113363592A (zh) * 2021-06-08 2021-09-07 四川启睿克科技有限公司 一种芯片与电池一体化集成方法及设备
US20240389890A1 (en) * 2021-09-27 2024-11-28 Medtrum Technologies Inc. Analyte detection system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2332466B1 (en) * 2004-07-13 2014-04-09 DexCom, Inc. Transcutaneous analyte sensor
CN202266572U (zh) * 2011-09-21 2012-06-06 深圳市理邦精密仪器股份有限公司 一种密封装配结构
CN106470593A (zh) * 2014-02-24 2017-03-01 美多尼克监测公司 可分离式监测装置和方法
CN210204726U (zh) * 2019-01-31 2020-03-31 青岛光电医疗科技有限公司 一次性防水型心电电极及移动式心电监测设备
CN110584676A (zh) * 2019-08-19 2019-12-20 上海移宇科技股份有限公司 传感装置
CN112394097A (zh) * 2019-08-19 2021-02-23 上海移宇科技股份有限公司 微型分析物检测装置

Also Published As

Publication number Publication date
EP4106613B1 (en) 2025-04-09
WO2021164185A1 (en) 2021-08-26
CN116785528A (zh) 2023-09-22
US20230092945A1 (en) 2023-03-23
EP4107526A1 (en) 2022-12-28
CN113274003A (zh) 2021-08-20
EP4017360B1 (en) 2025-08-13
EP4346593A1 (en) 2024-04-10
EP4017361A1 (en) 2022-06-29
CN113281382B (zh) 2025-01-28
WO2022252550A1 (en) 2022-12-08
EP4107526A4 (en) 2024-05-22
CN113274006A (zh) 2021-08-20
EP4106628A4 (en) 2024-05-01
WO2021164085A1 (en) 2021-08-26
US20230210408A1 (en) 2023-07-06
US20230066226A1 (en) 2023-03-02
CN112386251A (zh) 2021-02-23
CN114052728A (zh) 2022-02-18
CN115474928B (zh) 2025-10-31
CN113274013A (zh) 2021-08-20
CN115483485B (zh) 2023-11-21
EP4017357A4 (en) 2023-04-19
EP4017361B1 (en) 2025-06-18
CN112386251B (zh) 2024-08-20
US20230255517A1 (en) 2023-08-17
WO2021031541A1 (en) 2021-02-25
CN115474932B (zh) 2025-09-02
CN113274002A (zh) 2021-08-20
US12402815B2 (en) 2025-09-02
CN113274005A (zh) 2021-08-20
WO2021164184A1 (en) 2021-08-26
WO2023173654A1 (en) 2023-09-21
US20220218240A1 (en) 2022-07-14
WO2021164207A1 (en) 2021-08-26
ES3058746T3 (en) 2026-03-12
US20240245327A1 (en) 2024-07-25
CN113285268A (zh) 2021-08-20
EP4182677B1 (en) 2025-12-31
CN113274006B (zh) 2023-09-26
US20220234039A1 (en) 2022-07-28
EP4183339A1 (en) 2023-05-24
EP4182677A4 (en) 2024-08-14
EP4183339A4 (en) 2024-07-24
US12622610B2 (en) 2026-05-12
EP4182677A1 (en) 2023-05-24
CN113940673A (zh) 2022-01-18
WO2022252549A1 (en) 2022-12-08
WO2022012400A1 (en) 2022-01-20
CN115474932A (zh) 2022-12-16
CN115474928A (zh) 2022-12-16
US20250195759A1 (en) 2025-06-19
EP4017357A1 (en) 2022-06-29
CN114052728B (zh) 2025-06-03
WO2021031542A1 (en) 2021-02-25
WO2022252744A1 (en) 2022-12-08
WO2021164183A1 (en) 2021-08-26
WO2021031057A1 (en) 2021-02-25
US20230263433A1 (en) 2023-08-24
CN115483489B (zh) 2023-11-21
CN115483489A (zh) 2022-12-16
WO2022012187A1 (zh) 2022-01-20
EP4017361A4 (en) 2023-06-07
CN113274013B (zh) 2023-07-04
CN113285268B (zh) 2023-09-12
EP4106613A4 (en) 2024-04-17
EP4346593A4 (en) 2025-05-07
US20230066019A1 (en) 2023-03-02
EP4493057A1 (en) 2025-01-22
EP4017360A4 (en) 2023-09-06
EP4190237A4 (en) 2024-08-14
CN115483485A (zh) 2022-12-16
EP4183339B1 (en) 2026-04-01
US12484810B2 (en) 2025-12-02
WO2021164206A1 (en) 2021-08-26
WO2022252548A1 (en) 2022-12-08
CN113281382A (zh) 2021-08-20
CN113274003B (zh) 2023-09-12
EP4017360A1 (en) 2022-06-29
EP4493057A4 (en) 2025-12-17
CN113274005B (zh) 2024-02-13
CN113274002B (zh) 2023-04-28
CN113940673B (zh) 2024-02-13
EP4106628A1 (en) 2022-12-28
US20240225492A1 (en) 2024-07-11
CN112394097A (zh) 2021-02-23
EP4190237A1 (en) 2023-06-07
US12521044B2 (en) 2026-01-13
WO2021164278A1 (en) 2021-08-26
EP4106613A1 (en) 2022-12-28
US20220225900A1 (en) 2022-07-21

Similar Documents

Publication Publication Date Title
US20230210408A1 (en) Body fluid analyte detection device and continuous glucose monitoring device
CN113940670B (zh) 高可靠性分析物检测器件
CN114432535A (zh) 贴片式药物输注装置
WO2022252002A1 (zh) 体液分析物检测器件
CN115474931A (zh) 体液分析物检测器件
EP4237042A1 (en) A patch-type drug infusion device
US20260083356A1 (en) Installation unit for analyte detection device

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21854556

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2021854556

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2021854556

Country of ref document: EP

Effective date: 20230303