WO2024240071A1 - 用于样本检测设备的控制方法、样本检测设备及存储介质 - Google Patents

用于样本检测设备的控制方法、样本检测设备及存储介质 Download PDF

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Publication number
WO2024240071A1
WO2024240071A1 PCT/CN2024/093875 CN2024093875W WO2024240071A1 WO 2024240071 A1 WO2024240071 A1 WO 2024240071A1 CN 2024093875 W CN2024093875 W CN 2024093875W WO 2024240071 A1 WO2024240071 A1 WO 2024240071A1
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WIPO (PCT)
Prior art keywords
central control
control device
control instruction
target
instruction
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/CN2024/093875
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English (en)
French (fr)
Inventor
戴立忠
解亚平
罗满华
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Sansure Biotech Inc
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Sansure Biotech Inc
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Publication date
Priority claimed from CN202310580606.6A external-priority patent/CN118995405A/zh
Priority claimed from CN202310579473.0A external-priority patent/CN118995404A/zh
Priority claimed from CN202321246461.8U external-priority patent/CN219907658U/zh
Application filed by Sansure Biotech Inc filed Critical Sansure Biotech Inc
Priority to EP24810317.8A priority Critical patent/EP4596669A4/en
Publication of WO2024240071A1 publication Critical patent/WO2024240071A1/zh
Priority to US19/193,842 priority patent/US20250258189A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00—Program-control systems
    • G05B19/02—Program-control systems electric
    • G05B19/04—Program control other than numerical control, i.e. in sequence controllers or logic controllers
    • G05B19/042—Program control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
    • G05B19/0421—Multiprocessor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00752—Type of codes bar codes

Definitions

  • the present invention relates to the field of equipment control, and in particular to a control method for a sample detection device, a sample detection device and a storage medium.
  • PCR technology is a molecular biological technology used to amplify specific deoxyribonucleic acid (DNA) fragments.
  • DNA deoxyribonucleic acid
  • PCR technology has been widely used in the field of biological sample detection such as gene diagnosis and disease diagnosis.
  • the sample detection device based on PCR technology usually includes a control device and multiple execution devices, among which the execution device is a robotic arm and an electric gripper.
  • the control device is used to control the execution device to perform actions such as grabbing a test tube and shaking the test tube, so that the operator can perform sample detection while being away from the sample detection device.
  • the sample detection device includes a large number of actuators, and the control device is required to control multiple actuators at the same time.
  • the control device needs to integrate multiple control functions, which leads to the complexity of the instructions and structure of the control device. Since the control device needs to send a large number of instructions at the same time, the overall process response time of the sample detection device is required to be short.
  • the complexity of the instructions of the control device leads to control delays in the instructions of the control device, which makes it easy for the sample detection device to perform abnormalities, and thus it is impossible to obtain effective sample detection results.
  • the control device of the sample detection device is usually a control chip that integrates multiple control functions. When one control function of the control chip is abnormal, the entire control device needs to be replaced, which is inconvenient for maintenance.
  • the complexity of the instructions and structure of the control device increases the probability of abnormalities during the operation of the sample detection device, which easily leads to the inability to obtain effective sample detection results.
  • the purpose of the embodiments of the present invention is to provide a control method for a sample detection device, a sample detection device and a storage medium.
  • the control method for the sample detection device is used to solve the problem that the instructions and structure of the control device of the sample detection device are complicated, resulting in the inability to obtain effective sample detection results.
  • the present application provides a control method for a sample detection device, the sample detection device comprising a main control device, a plurality of central control devices and a plurality of driving devices, and the control method for the sample detection device comprises:
  • the target central control device Utilizing the target central control device to parse the main control instruction, generate a combination logic central control instruction, and send the combination logic central control instruction to the target drive device, wherein the target drive device is a drive device connected to the target central control device;
  • the target drive device is used to respond to the combinational logic central control instructions to execute the actions of the detection process.
  • the present application provides a sample detection device, the sample detection device comprising a main control device, a plurality of central control devices and a plurality of drive devices;
  • a main control device which is used to generate a main control instruction based on the detection process of the sample, and send the main control instruction to each central control device, wherein the main control instruction is used to control the target central control device to execute the detection process, and the target central control device is a central control device that can parse the main control instruction;
  • the target central control device is used to parse the main control instruction, generate the combinational logic central control instruction, and send the combinational logic central control instruction to the target drive device, wherein the target drive device is a drive device connected to the target central control device;
  • the target drive device is used to respond to the combinational logic central control instructions and execute the actions of the detection process.
  • the present application provides a computer-readable storage medium having a computer program stored thereon.
  • the machine program is executed by the processor, the above-mentioned control method for the sample detection device is implemented.
  • the main control device controls the central control device and the central control device controls the driving device, which simplifies the main control instructions and structure of the main control device, reduces the probability of abnormalities in the sample detection device, and ensures that the sample detection device obtains effective sample detection results.
  • the central control device controls the driving device, which simplifies the main control instructions and structure of the main control device, reduces the probability of abnormalities in the sample detection device, and ensures that the sample detection device obtains effective sample detection results.
  • FIG1 is a flow chart showing a control method for a sample detection device provided in Embodiment 1 of the present application;
  • FIG2 shows a schematic diagram of the structure of a sample detection device provided in Example 1 of the present application
  • FIG3 shows a flow chart of a control method for a sample detection device provided in Embodiment 2 of the present application
  • FIG4 shows a schematic diagram of the structure of a sample detection device provided in Example 2 of the present application.
  • FIG5 is a flow chart showing a control method for a sample detection device provided in Embodiment 3 of the present application.
  • FIG6 shows a schematic diagram of the structure of a sample detection device provided in Embodiment 3 of the present application.
  • FIG. 7 shows a first structural schematic diagram of a control device for a sample detection device provided in Embodiment 4 of the present application.
  • FIG8 shows a schematic structural diagram of an opening and closing cover control panel provided in Embodiment 4 of the present application.
  • FIG9 shows a schematic structural diagram of a pipetting control board provided in Example 4 of the present application.
  • FIG10 shows a schematic diagram of the structure of a sample delivery control board provided in Embodiment 4 of the present application.
  • FIG11 shows a schematic diagram of the structure of a central control panel provided in Embodiment 4 of the present application.
  • FIG12 shows a second structural schematic diagram of a control device for a sample detection device provided in Embodiment 4 of the present application.
  • 200-sample detection equipment 200-sample detection equipment; 210-main control device, 220-central control device, 230-driving device.
  • 400-sample detection equipment 410-main control device, 420-central control device, 430-driving device; 421-opening and closing lid central control device, 422-liquid transfer central control device, 423-extraction central control device.
  • FIG1 shows a flow chart of a control method for a sample detection device provided in Embodiment 1 of the present application.
  • the sample detection device includes a main control device, multiple central control devices, and multiple drive devices.
  • the control method for the sample detection device in FIG1 includes:
  • FIG. 2 shows a schematic diagram of the structure of a sample detection device provided in Example 1 of the present application.
  • the sample detection device 200 includes a main control device 210, a plurality of central control devices 220, and a plurality of driving devices 230. For ease of understanding, only one central control device 220 and one driving device 230 are shown in the figure.
  • the main control device 210 obtains the sample detection process, wherein the sample detection process is set according to actual needs and is not limited here.
  • the sample detection process can be directly stored in the main control device 210.
  • the sample detection device can also be connected to an external device, and the sample detection process is sent to the main control device 210 through the external device, and then the sample detection device is remotely controlled through the external device.
  • the main control device 210 sends the main control instruction to each central control device 220, wherein the main control instruction is used to control the target central control device to execute the detection process, and the target central control device is the central control device 220 that can parse the main control instruction. All central control devices 220 receive the main control instruction, and only the target central control device responds to the main control instruction and controls the drive device 230, ensuring that the sample detection device 200 performs detection based on the detection process of the sample.
  • the main control device 210 controls the operation of the central control device 220 to control the drive device 230 through the central control device 220, simplifies the main control instruction of the main control device 210, reduces the probability of abnormal situations such as long instruction delay, and enables the sample detection device 200 to obtain effective sample detection results.
  • the main control instructions include the main control instructions of the lid opening and closing process, the main control instructions of the liquid transfer sub-process, the main control instructions of the extraction sub-process, the main control instructions of the sample delivery process and the main control instructions of the detection sub-process.
  • the main control device determines the sample detection process as multiple sub-processes and generates a main control instruction for each sub-process.
  • the sample detection process in the embodiment of the present application is determined as a plurality of sub-processes such as the lid opening and closing process, the liquid transfer sub-process, the extraction sub-process, the sample delivery process, and the detection sub-process.
  • the main control instructions correspond to the main control instructions for the lid opening and closing process, the main control instructions for the liquid transfer sub-process, the main control instructions for the extraction sub-process, the main control instructions for the sample delivery process, and the main control instructions for the detection sub-process.
  • the master control instruction is used to control the central control device, so that the central control device controls the drive device to execute the sample detection process.
  • the combinational logic central control instruction is used to control the drive device to execute the sample detection process.
  • the master control device only needs to control the operation of the central control device through the master control instruction, thereby simplifying the instructions of the master control device.
  • the target central control device responds to the master control instruction.
  • the central control device is a central control device that can parse the master control instruction and determine the combined action that needs to be performed by all target drive devices together, wherein the target drive device is a drive device connected to the target central control device.
  • the target central control device generates a combination logic central control instruction based on the combined action, and sends the combination logic central control instruction to the target drive device.
  • one target central control device is usually connected to at least one target drive device.
  • the target central control device needs to control the target drive device to perform a combination action consisting of multiple actions such as the gun head removal action, the liquid aspiration action, the liquid injection action and the gun head removal action.
  • the target central control device controls the target drive device to complete the combined action together through the combination logic central control instruction to complete a sub-process of the sample detection process.
  • the main control device sends the main control instruction to multiple central control devices, the target central control device responds to the main control instruction, and the central control devices other than the target central control device do not respond to the main control instruction. Even if there is a delay in the transmission and response of the instruction, the sample detection device can still complete each sub-process of the detection process in sequence, thereby enabling the sample detection device to perform detection based on the sample detection process.
  • each central control device determines whether to respond and generates a combinational logic central control instruction corresponding to the sample detection process.
  • the target drive device After the target drive device receives the combinational logic central control instruction, the target drive device directly responds to the combinational logic central control instruction and executes the action of the detection process.
  • the drive device does not need to determine whether to respond to the instruction sent by the main control device, but can directly execute the action, which avoids the main control device's instruction not being correctly responded to by the drive device, and ensures that the sample detection device can perform detection based on the sample detection process. Since the main control device, multiple central control devices and multiple drive devices are not integrated into an integrated device, when the sample detection device is abnormal, only the device where the abnormality occurs needs to be replaced. For example, when one of the central control devices is abnormal, only the central control device where the abnormality occurs needs to be replaced, and there is no need to replace the main control device, the central control device and the drive device together.
  • control method for the sample detection device also includes:
  • the target driving device When the target driving device completes the action, the target driving device is used to generate an action completion signal, and the action signal is sent to the target central control device;
  • the target central control device is used to send the combinational logic central control instruction to the next target drive device.
  • the target central control device is required to send the combination logic central control instruction to each target drive device in turn to control multiple target drive devices to jointly perform the combined action of the pipetting sub-process.
  • the target central control device sends the combination logic central control instruction to the target drive device, and after the target drive device completes the action of taking the gun tip, the target drive device generates an action completion signal and sends the action signal to the target central control device.
  • the target central control device detects whether the main control instruction is completed according to the action completion signal.
  • the target central control device determines the combined action of the pipetting sub-process according to the main control instruction of the pipetting sub-process.
  • the target central control device determines that the completed pipetting sub-process action is the gun tip removal action according to the action completion signal, and it is not the last action of the combined action, and then determines that the central control device has not completed the main control instruction.
  • the target central control device sends the combination logic central control instruction to the next target drive device, and controls the next target drive device to perform the liquid aspiration action.
  • the central control device In the case where the completed pipetting sub-process action is the last action of the combined action, it is determined that the central control device has completed the main control instruction but has not completed the main control instruction. Compared with the central control device directly sending instructions to all drive devices, the central control device sends instructions to each drive device in turn according to the action completion signal. Even if there is a delay in the transmission and response of the instruction, the sample detection device will not execute the action of the next detection process in advance, ensuring that the sample detection device can perform detection based on the sample detection process.
  • control method for the sample detection device also includes:
  • the steps of using the main control device to perform a sample-based detection process, generate a main control instruction, and send the main control instruction to each central control device are performed.
  • the central control device After the central control device determines that the main control instruction is completed according to the action completion signal sent by the driving device, it generates an instruction completion signal and sends the instruction completion signal to the main control device.
  • the main control device determines whether the sample detection is completed based on the instruction completion signal. Specifically, the main control device determines the completed sub-process based on the instruction completion signal, and determines whether the completed sub-process is the last process of the detection process. If the completed sub-process is the last process of the detection process, it is determined that the sample detection is completed.
  • the main control device determines the next sub-process based on the sample detection process.
  • the main control device generates a main control instruction for the next sub-process and sends the main control instruction for the next sub-process to each central control device. Repeat the steps of using the main control device to generate a main control instruction based on the sample detection process and sending the main control instruction to each central control device until the sample detection device completes all sub-processes of the sample detection process, so that the sample detection device can perform detection based on the sample detection process.
  • the central control device includes a functional central control device, which uses a target central control device to parse a main control instruction, generates a combination logic central control instruction, and sends the combination logic central control instruction to a target drive device, including:
  • the functional central control device is used to parse the main control instruction to generate a fifth combination logic central control instruction, and the fifth combination logic central control instruction is sent to each target drive device in turn, wherein the fifth combination logic central control instruction is used to control the target drive device to perform a combination action of adjusting the detection environment.
  • the functional central control device responds to the main control instruction, and the central control devices other than the functional central control device do not respond to the main control instruction.
  • the functional central control device is used to parse the main control instruction to generate the fifth combinational logic central control instruction to control the target drive
  • the device executes a combination action of adjusting the detection environment, wherein the combination action of adjusting the detection environment includes a temperature adjustment action, an exhaust action, etc., which will not be elaborated here.
  • the target drive device includes an exhaust device and a temperature control device.
  • the target central control device sequentially sends the fifth combination logic central control instruction to each target drive device in turn.
  • the exhaust device responds to the combination logic central control instruction and performs an exhaust action;
  • the temperature control device responds to the combination logic central control instruction and performs an adjustment action, thereby adjusting the detection environment of the sample detection device to prevent the sample from being contaminated.
  • the present application provides a control method for a sample detection device, in which a central control device controls a driving device, and the driving device directly performs a detection action after receiving a command from the central control device.
  • the driving device no longer needs to determine whether to respond to the received command, thereby avoiding the situation where the command of the main control device is not correctly responded to by the driving device, and ensuring that the sample detection device can perform detection based on the detection process of the sample.
  • FIG3 shows a flow chart of a control method for a sample detection device provided in Example 2 of the present application.
  • the sample detection device includes a main control device, multiple central control devices, and multiple drive devices.
  • the control method for the sample detection device in FIG3 includes:
  • FIG. 4 shows a schematic diagram of the structure of a sample detection device provided in the second embodiment of the present application.
  • the central control device 420 in the sample detection device 400 includes a cover opening and closing central control device 421, a liquid transfer central control device 422, and an extraction central control device 423.
  • the main control device 410 generates a main control instruction based on the sample detection process, and sends the main control instruction to the cover opening and closing central control device 421, the liquid transfer central control device 422, and the extraction central control device 423.
  • the figure only shows a driving device 430 connected to the cover opening and closing central control device 421, a driving device 430 connected to the liquid transfer central control device 422, and a driving device 430 connected to the extraction central control device 423.
  • the sample detection process includes a lid opening process, a reagent aspiration sub-process, a lid closing process, a nucleic acid extraction sub-process, and a reagent mixing sub-process.
  • the main control device 410 Based on the sample detection process, the main control device 410 generates a master control instruction for the lid opening process, a master control instruction for the reagent aspiration sub-process, a master control instruction for the lid closing process, a master control instruction for the nucleic acid extraction sub-process, and a master control instruction for the reagent mixing sub-process, and sends each master control instruction to the lid opening and closing central control device 421, the pipetting central control device 422, and the extraction central control device 423 in turn.
  • the opening and closing cover central control device is used to parse the main control instruction, generate a first combination logic central control instruction, and send the first combination logic central control instruction to each target driving device in sequence.
  • the main control device generates the master control instruction of the lid opening process, and sends the master control instruction of the lid opening process to each central control device.
  • the target central control device responds to the master control instruction, while the pipetting central control device and the extraction central control device do not respond to the master control instruction, that is, the target central control device is the lid opening and closing central control device.
  • the lid opening and closing central control device is used to parse the main control instruction to generate a first combination logic central control instruction, wherein the first combination logic central control instruction generated by parsing the main control instruction of the lid opening process is used to control the target drive device to perform the combination action of lid opening.
  • the lid opening and closing central control device sends the first combination logic central control instruction to each target drive device corresponding to the lid opening process in sequence, and controls multiple target drive devices to jointly perform the combination action of lid opening, wherein the combination action of lid opening includes the action of grabbing the test tube and the action of opening the test tube cover.
  • each target drive device performs an action, that is, one target drive device performs the test tube grabbing action, and the other target drive device performs the test tube cover opening action, and then the two target drive devices jointly perform the combined action of opening the cover.
  • the pipetting central control device when the target central control device is a pipetting central control device, the pipetting central control device is used to parse the main control instruction, generate a second combination logic central control instruction, and send the second combination logic central control instruction to each target driving device in sequence.
  • the main control device responds to the command completion signal and sends the reagent aspirating subprocess main control command to each central control device.
  • the target central control device that responds to the main control command is the liquid transfer central control device.
  • the target central control device parses the main control command to generate a second combination logic central control command, wherein the second combination logic central control command generated by parsing the main control command of the reagent aspirating subprocess is used to control the target drive device to perform the combined action of aspirating the reagent.
  • the target central control device sends the second combination logic central control instruction to each target drive device corresponding to the reagent absorption sub-process in sequence, controlling A plurality of target driving devices jointly execute a combined action of drawing reagents, wherein the combined action of drawing reagents includes an action of taking a gun tip, drawing a test sample and injecting it into a deep-well plate.
  • the main control device responds to the instruction completion signal and sends the main control instruction of the lid closing process to each central control device.
  • the target central control device that responds to the main control instruction is the lid opening and closing central control device.
  • the target central control device parses the main control instruction to generate a first combination logic central control instruction, wherein the first combination logic central control instruction generated by parsing the main control instruction of the lid closing process is used to control the target drive device to perform the combination action of lid closing.
  • the target central control device sends the first combination logic central control instruction to each target drive device corresponding to the lid closing process in sequence, and controls multiple target drive devices to jointly perform the combined action of lid closing, wherein the combined action of lid closing includes the action of closing the test tube lid and the action of placing the test tube into the carrier.
  • the extracted central control device when the target central control device is the extracted central control device, the extracted central control device is used to parse the main control instruction, generate a third combination logic central control instruction, and send the third combination logic central control instruction to each target driving device in sequence.
  • the main control device After completing the required number of sample collections, the main control device responds to the instruction completion signal and sends the main control instruction of the nucleic acid extraction subprocess to each central control device.
  • the target central control device that responds to the main control instruction is the liquid transfer central control device.
  • the target central control device parses the main control instruction to generate a third combinational logic central control instruction, wherein the third combinational logic central control instruction generated by parsing the main control instruction of the nucleic acid extraction subprocess is used to control the target drive device to perform the combined action of nucleic acid extraction.
  • the target central control device sends the third combination logic central control instruction to each target drive device corresponding to the nucleic acid extraction sub-process in sequence, and controls multiple target drive devices to jointly perform the combined action of extracting nucleic acid, wherein the combined action of extracting nucleic acid includes removing the magnetic rod cover action, cell lysis action, nucleic acid adsorption and transfer action, and nucleic acid washing and purification action.
  • the main control device responds to the instruction completion signal and sends the main control instruction of the reagent mixing sub-process to each central control device.
  • the target central control device that responds to the main control instruction is the lid opening and closing central control device.
  • the target central control device parses the main control instruction to generate a second combination logic central control instruction, wherein the second combination logic central control instruction generated by parsing the main control instruction of the reagent mixing sub-process is used to control the target drive device to perform the combination action of mixing reagents.
  • the target central control device sends the second combination logic central control instruction to each target drive device corresponding to the mixed reagent sub-process in sequence, and controls multiple target drive devices to jointly perform the combined action of mixed reagents, wherein the combined action of mixed reagents includes the action of removing the gun tip, the action of removing the plunger, the action of injecting the purified nucleic acid liquid and the detection reagent into the reagent cartridge, the action of mixing the reagent cartridge, and the action of pressing the plunger.
  • the target drive device directly responds to the combination logic central control command and executes an action of the detection process.
  • the sample detection process is divided into multiple actions, each drive device executes an action, and the combined action of the detection process is obtained, and then the reagent cartridge to be detected is obtained.
  • FIG5 shows a flow chart of a control method for a sample detection device provided in Example 3 of the present application.
  • the sample detection device includes a main control device, multiple central control devices, and multiple driving devices.
  • the control method for the sample detection device in FIG5 includes:
  • FIG. 6 shows a schematic diagram of the structure of a sample detection device provided in Embodiment 3 of the present application.
  • the central control device 620 in the sample detection device 600 includes a sample delivery central control device 621 and a detection central control device 622.
  • the main control device 610 generates a main control instruction based on the sample detection process, and sends the main control instruction to the sample delivery central control device 621 and the detection central control device 622.
  • the figure only shows one driving device 630 connected to the sample delivery central control device 621 and one driving device 630 connected to the detection central control device 622.
  • the sample testing process includes a sample delivery process and a detection sub-process.
  • the main control device 610 generates a main control instruction for the sample delivery process and a main control instruction for the detection sub-process based on the sample detection process, and sends each main control instruction to the sample delivery central control device 621 and the detection central control device 622 in turn.
  • the sample delivery central control device when the target central control device is a sample delivery central control device, the sample delivery central control device is used to parse the main control instruction, generate a fourth combination logic central control instruction, and send the fourth combination logic central control instruction to each target drive device in sequence.
  • the main control device After obtaining the reagent cartridge to be tested, the main control device responds to the command completion signal and sends the main control command of the sample delivery process to each
  • the target central control device that responds to the master control instruction is the sample delivery central control device.
  • the target central control device parses the master control instruction to generate a fourth combinational logic central control instruction, wherein the fourth combinational logic central control instruction generated by parsing the master control instruction of the sample delivery process is used to control the target drive device to perform the sample delivery combination action.
  • the target central control device sends the fourth combination logic central control instruction to each target drive device corresponding to the sample delivery process in sequence, and controls multiple target drive devices to jointly perform the combined action of sample delivery, wherein the combined action of sample delivery includes opening the door of the detection position, transferring the reagent cartridge to the detection position, closing the door of the detection position, opening the detection cartridge, inserting the reagent cartridge into the detection position, and closing the detection cartridge.
  • the detection central control device when the target central control device is a detection central control device, the detection central control device is used to parse the main control instruction, generate a sixth combination logic central control instruction, and send the sixth combination logic central control instruction to each target driving device in sequence.
  • the main control device After completing the sample sending process, the main control device responds to the instruction completion signal and sends the main control instruction of the detection sub-process to each central control device.
  • the target central control device that responds to the main control instruction is the detection central control device.
  • the target central control device parses the main control instruction to generate a sixth combination logic central control instruction, wherein the sixth combination logic central control instruction generated by parsing the main control instruction of the detection sub-process is used to control the target drive device to perform a combination action of obtaining sample detection data.
  • the target central control device sends the sixth combination logic central control instruction to each target drive device corresponding to the detection sub-process in sequence, and controls multiple target drive devices to jointly perform the combination action of obtaining sample detection data, wherein the combination action of obtaining sample detection data includes nucleic acid amplification action and single sample detection data.
  • the first combination logic central control instruction, the second combination logic central control instruction, the third combination logic central control instruction, the fourth combination logic central control instruction, the fifth combination logic central control instruction and the sixth combination logic central control instruction in the embodiments of the present application are only used to distinguish the description and cannot be understood as indicating or implying relative importance.
  • control method for the sample detection device also includes:
  • the main control device is used to obtain the sample detection data obtained by the detection central control device, and generate a sample detection result based on the sample detection data.
  • the detection central control device sends the acquired sample detection data to the main control device, and the main control device generates a sample detection result based on the sample detection data.
  • the central control device can be implemented by a control board, etc., which will not be elaborated here.
  • the drive device can be regarded as a device including the central control device.
  • the sample detection device in the embodiment of the present application includes a PCR sample detection device.
  • the target drive device directly responds to the combination logic central control command and executes an action of the detection process.
  • the sample detection process is divided into multiple actions, each drive device executes an action, and the combined action of the detection process is obtained, and then the sample detection result is obtained.
  • FIG. 7 shows a first structural schematic diagram of a control device for a sample detection device provided in Embodiment 4 of the present application.
  • the control device 1000 is used to control the sample detection device, and the control device 1000 includes: a main control device 1100, a plurality of central control devices 1200 and a plurality of driving devices 1300;
  • each central control device 1200 is connected to the main control device 1100, and the other end is connected to at least one driving device 1300;
  • the main control device 1100 is used to generate a main control instruction based on the detection process of the sample, and send the main control instruction to each central control device 1200, wherein the main control instruction is used to control the central control device 1200 to execute the detection process;
  • the central control device 1200 is used to parse the main control instruction, generate a combinational logic central control instruction, and send the combinational logic central control instruction to the drive device 1300;
  • the driving device 1300 is used to respond to the combinational logic central control instruction and execute the action of the detection process.
  • each central control device 1200 is connected to the main control device 1100, and the other end of the central control device 1200 is connected to at least one drive device 1300.
  • the connection method between the main control device 1100 and the central control device 1200 is set according to actual needs, and can be an RS (Recommended Standard) 232 bus connection or a CAN bus connection, which is not limited here.
  • the connection method between the drive device 1300 and the central control device 1200 is also set according to actual needs, which is not limited here.
  • the number of central control devices 1200 and drive devices 1300 is set according to actual needs, and the number of drive devices 1300 connected to each central control device 1200 is also set according to actual needs, which is not limited here. For ease of understanding, only two central control devices 1200 and four drive devices 1300 are shown in the figure, and each central control device 1200 is connected to two drive devices 1300.
  • the main control device 1100 determines the sample detection process as multiple sub-processes and generates a main control instruction for each sub-process.
  • the sample detection process in the embodiment of the present application consists of multiple sub-processes such as the lid opening and closing process, the liquid transfer sub-process, the extraction sub-process, the sample delivery process, and the detection sub-process.
  • the control device 1000 includes multiple central control devices 1200, and each central control device 1200 is used to control the drive device 1300 to perform at least one sub-process action.
  • the central control device 1200 that responds to the main control instruction of the lid opening and closing process is the target central control device; in the case of the extraction sub-process, the central control device 1200 that responds to the main control instruction of the extraction sub-process is the target central control device, and the target central control devices of the remaining sub-processes are not described here.
  • the main control device 1100 sends the main control instruction to each central control device 1200, and the target central control device responds to the main control instruction and parses the main control instruction to determine the sub-process of the detection process.
  • the central control device 1200 detects the sub-process of the process, determines it as multiple actions, and generates a combination logic central control instruction according to the execution order of the multiple actions of the sub-process.
  • the main control device 1100 controls the operation of the central control device 1200 to control the driving device 1300 through the central control device 1200, simplifies the main control instructions of the main control device 1100, reduces the probability of abnormal situations such as long instruction delay, and enables the sample detection device to obtain effective sample detection results.
  • the target central control device sends each combination logic central control instruction to each target drive device 1300 in turn based on the execution order of multiple actions, wherein the target drive device 1300 is a target drive device 1300 connected to the target central control device.
  • Each drive device 1300 is controlled by the combination logic central control instruction to perform an action of the detection process, and then all actions of the detection process are completed by multiple drive devices 1300.
  • the drive device 1300 does not perform the action of the detection process if it does not receive the instruction.
  • the drive device 1300 directly performs the action of the detection process when it receives the instruction.
  • the drive device 1300 no longer needs to determine whether to respond to the received instruction, which avoids the instruction of the main control device 1100 not being correctly responded by the drive device 1300, and ensures that the sample detection device can be detected based on the detection process of the sample. Since the main control device 1100, multiple central control devices 1200 and multiple drive devices 1300 are not integrated into an integrated device, when an abnormality occurs in the sample detection device, only the abnormal device needs to be replaced. For example, when one of the central control devices 1200 malfunctions, only the malfunctioning central control device 1200 needs to be replaced, and there is no need to replace the main control device 1100 , the central control device 1200 , and the driving device 1300 together.
  • FIG. 8 shows a schematic diagram of the structure of the opening and closing cover control panel provided in the fourth embodiment of the present application.
  • the central control device 1200 includes an opening and closing cover control board 1210
  • the driving device 1300 includes a barcode scanner 1311, a first power supply control board 1312, and multiple opening and closing cover motor control boards 1313, multiple first clamps 1314, and multiple second clamps 1315;
  • the opening and closing cover control board 1210 is respectively connected to the barcode scanner 1311, the first power supply control board 1312, the opening and closing cover motor control board 1313, the first clamping claw 1314 and the second clamping claw 1315;
  • a barcode scanner 1311 is used to obtain barcode information of the sample tube
  • a first power supply control board 1312 used to control the power supply status of the opening and closing cover motor control board 1313, the first clamping jaw 1314, and the second clamping jaw 1315;
  • the cover opening and closing motor control board 1313 is used to control the motor operation state of the cover opening and closing mechanical arm
  • the first clamping jaw 1314 is used to clamp the cap of the reagent cartridge
  • the second clamping claw 1315 is used to clamp the base of the reagent cartridge.
  • the detection process of the sample is determined as multiple sub-processes.
  • the opening and closing lid control board 1210 is used to respond to the main control instructions of the main control device 1100, and the central control device 1200 other than the opening and closing lid control board 1210 does not respond to the main control instructions of the main control device 1100.
  • the opening and closing lid control board 1210 parses the main control instructions and generates combinational logic central control instructions. Based on the action sequence of the opening and closing lid process, the opening and closing lid control board 1210 sends combinational logic central control instructions to multiple drive devices 1300 in sequence, wherein the action sequence of the opening and closing lid process is set according to actual needs and will not be elaborated here.
  • the opening and closing lid central control device includes the opening and closing lid control board 1210 and other devices, and the other devices are set according to the actual opening and closing lid process and are not limited here.
  • the sample detection equipment needs to detect multiple samples at the same time.
  • the barcode scanner 1311 obtains the barcode information of the sample test tube to distinguish multiple samples.
  • the first power supply control board 1312 controls the power supply status of the opening and closing cover motor control board 1313, the first clamp 1314, and the second clamp 1315.
  • the opening and closing cover motor control board 1313 controls the motor working state of the opening and closing cover mechanical arm.
  • the first clamp 1314 clamps the cap of the reagent cartridge.
  • the second clamp 1315 clamps the base of the reagent cartridge.
  • the clamping position, clamping force value, running speed, rotation angle and other parameters of the first clamp 1314 and the second clamp 1315 are controlled by the opening and closing cover control board 1210, so that multiple drive devices execute the opening and closing cover flow such as clamping the test tube, opening the test tube cover and closing the test tube cover.
  • the action of the process is controlled, and then the sample detection equipment is controlled to carry out the sample detection process.
  • the number of the opening and closing cover motor control board 1313, the first clamping jaw 1314 and the second clamping jaw 1315 is set according to actual needs and is not limited here.
  • the figure only shows one opening and closing cover motor control board 1313, one first clamping jaw 1314 and one second clamping jaw 1315, and does not show the connection relationship between the first power supply control board 1312 and the opening and closing cover motor control board 1313, the first clamping jaw 1314 and the second clamping jaw 1315.
  • Figure 9 shows a schematic structural diagram of the pipetting control board provided in Example 4 of the present application.
  • the central control device 1200 includes a pipetting control board 1220
  • the driving device 1300 includes a second power supply control board 1321, a gun tip discarding door motor control board 1322, and a plurality of pipetting pumps 1323, a plurality of pipetting motor control boards 1324, and a plurality of plunger removal motor control boards 1325;
  • the liquid transfer control board 1220 is respectively connected to the second power supply control board 1321, the gun tip discarding door motor control board 1322, the liquid transfer pump 1323, the liquid transfer motor control board 1324 and the plunger removal motor control board 1325;
  • the second power supply control board 1321 is used to control the power supply status of the gun tip discarding door motor control board 1322, the liquid transfer pump 1323, the liquid transfer motor control board 1324 and the plunger removal motor control board 1325;
  • the gun tip discarding door motor control board 1322 is used to control the motor operation state of the gun tip discarding device
  • a pipette pump 1323 used for sucking or discharging liquid
  • the liquid transfer motor control board 1324 is used to control the motor operation state of the liquid transfer robot arm
  • the plunger removal motor control board 1325 is used to control the motor operation state of the plunger removal device.
  • the sample detection process is determined as multiple sub-processes.
  • the pipetting control board 1220 is used to respond to the main control instructions of the main control device 1100, and the central control device 1200 other than the pipetting control board 1220 does not respond to the main control instructions of the main control device 1100.
  • the pipetting control board 1220 parses the main control instructions and generates combinational logic central control instructions. Based on the action sequence of the pipetting sub-process, the pipetting control board 1220 sends the combinational logic central control instructions to multiple driving devices 1300 in sequence, wherein the action sequence of the pipetting sub-process is set according to actual needs and will not be elaborated here.
  • the central control device 1200 is a pipetting central control device
  • the pipetting central control device includes the pipetting control board 1220 and other devices, and the other devices are set according to the actual pipetting sub-process and are not limited here.
  • the second power supply control board 1321 controls the power supply status of the gun tip discarding door motor control board 1322, the pipetting pump 1323, the pipetting motor control board 1324 and the plunger removal motor control board 1325 when receiving the combinational logic central control command.
  • the gun tip discarding door motor control board 1322 controls the motor working state of the gun tip discarding device when receiving the combinational logic central control command.
  • the pipetting pump 1323 absorbs or discharges liquid when receiving the combinational logic central control command.
  • the pipetting motor control board 1324 controls the motor working state of the pipetting mechanical arm when receiving the combinational logic central control command.
  • the plunger removal motor control board 1325 controls the motor working state of the plunger removal device when receiving the combinational logic central control command.
  • the actions of the pipetting sub-processes such as the reagent absorption action, the liquid level detection action, the reagent discharge action, the gun tip removal action, and the gun tip removal action are executed through multiple driving devices, thereby controlling the sample detection device to perform the sample detection process.
  • the number of the pipetting pump 1323, the pipetting motor control board 1324 and the plunger removal motor control board 1325 is set according to actual needs and is not limited here.
  • the figure only shows one pipetting pump 1323, one pipetting motor control board 1324 and one plunger removal motor control board 1325, and does not show the connection relationship between the second power supply control board 1321 and the gun tip discarding door motor control board 1322, the pipetting pump 1323, the pipetting motor control board 1324 and the plunger removal motor control board 1325.
  • Figure 10 shows a schematic diagram of the structure of the sample delivery control board provided in Example 4 of the present application.
  • the central control device 1200 includes a sample delivery control board 1230
  • the driving device 1300 includes a third clamp 1331, a third power supply control board 1332, a feed door motor control board 1333, a cartridge discard door motor control board 1334, and multiple feed motor control boards 1335, multiple sample delivery arm motor control boards 1336, and multiple bin opening motor control boards 1337;
  • the sample delivery control board 1230 is respectively connected to the third clamping jaw 1331, the third power supply control board 1332, the feed door motor control board 1333, the cartridge discard door motor control board 1334, the feed motor control board 1335, the sample delivery arm motor control board 1336 and the bin opening motor control board 1337;
  • the third clamping jaw 1331 is used to clamp the reagent cartridge
  • a third power supply control board 1332 used for controlling the power supply state of the third clamping jaw 1331
  • the feed door motor control board 1333 is used to control the motor operation state of the feed device
  • the card box discarding door motor control board 1334 is used to control the motor operation state of the card box discarding device
  • the feeding motor control board 1335 is used to control the motor running state of the feeding device
  • the sample delivery arm motor control board 1336 is used to control the motor operation state of the sample delivery mechanical arm
  • the opening motor control board 1337 is used to control the motor operating state of the opening device.
  • the sample detection process is determined as multiple sub-processes.
  • the sample delivery control board 1230 is used to respond to the main control instructions of the main control device 1100, and the central control device 1200 other than the sample delivery control board 1230 does not respond to the main control instructions of the main control device 1100.
  • the sample delivery control board 1230 parses the main control instructions and generates combinational logic central control instructions. Based on the action sequence of the sample delivery process, the sample delivery control board 1230 sends the combinational logic central control instructions to multiple drive devices 1300 in sequence, wherein the action sequence of the sample delivery process is set according to actual needs and is not repeated here.
  • the central control device 1200 is a sample delivery central control device
  • the sample delivery central control device includes the sample delivery control board 1230 and other devices, and the other devices are set according to the actual sample delivery process and are not limited here.
  • the third clamp 1331 clamps the reagent cartridge when receiving the combination logic central control command.
  • the third power supply control board 1332 controls the power supply state of the third clamp 1331 when receiving the combination logic central control command.
  • the feed door motor control board 1333 controls the motor working state of the feed device when receiving the combination logic central control command.
  • the cartridge discard door motor control board 1334 controls the motor working state of the cartridge discard device when receiving the combination logic central control command.
  • the feed motor control board 1335 controls the motor working state of the feed device when receiving the combination logic central control command.
  • the sample delivery arm motor control board 1336 controls the motor working state of the sample delivery manipulator when receiving the combination logic central control command.
  • the warehouse opening motor control board 1337 controls the motor working state of the cabin opening device when receiving the combination logic central control command.
  • the opening detection position door action, the transfer of the reagent cartridge to the detection position action, the closing detection position door action, the opening detection cartridge action, the reagent cartridge insertion detection position action, and the closing detection cartridge action are executed through multiple drive devices. Wait for the sample delivery process to proceed, and then control the sample testing equipment to carry out the sample testing process.
  • the number of the multiple feeding motor control boards 1335, the sample feeding arm motor control boards 1336 and the bin opening motor control boards 1337 is set according to actual needs and is not limited here.
  • the figure only shows one of the multiple feeding motor control boards 1335, one sample feeding arm motor control board 1336 and one bin opening motor control board 1337, and does not show the connection relationship between the third power supply control board 1332 and the third clamping jaw 1331.
  • Figure 11 shows a schematic diagram of the structure of the central control panel provided in Example 4 of the present application.
  • the central control device 1200 includes a central control panel 1240
  • the driving device 1300 includes a fourth power supply control panel 1341, a laminar flow purification device 1342, a plurality of indicator light control panels 1343 and a plurality of ultraviolet devices 1344;
  • the central control panel 1240 is respectively connected to the fourth power supply control panel 1341, the laminar flow purification device 1342, the indicator light control panel 1343 and the ultraviolet device 1344;
  • a laminar flow purification device 1342 used to purify pollutants in the sample detection device
  • the ultraviolet device 343 is used to disinfect the sample detection equipment
  • the indicator light control panel 1343 is used to control the indication status of the indicator light
  • the fourth power supply control board 1341 is used to control the power supply status of the indicator light, the laminar flow purification device 1342 and the ultraviolet device 1344.
  • the main control device 1100 is also used to determine the working state of the sample detection device. Specifically, the main control device 1100 receives a working state determination request and generates a main control instruction.
  • the sample delivery control board 1230 is used to respond to the main control instruction of the main control device 1100, and the central control device 1200 other than the sample delivery control board 1230 does not respond to the main control instruction of the main control device 1100.
  • the fourth power supply control board 1341 controls the power supply state of the indicator light, the laminar flow purification device 1342 and the ultraviolet device 1344.
  • the central control board 1240 sends instructions to the indicator light control board 1343 and the fourth power supply control board 1341 according to the working state of the sample detection device.
  • the fourth power supply control board 1341 is used to control the power supply state of the indicator light.
  • the indicator light control board 1343 is used to control the indicator light to adjust to the indication state such as interval flashing and long light. It should be understood that the sample detection device can be configured to different working states according to actual needs, and the indicator light feedbacks the working state of the sample detection device through different indication states, which will not be repeated here.
  • the laminar flow purification device 1342 purifies the pollutants in the sample detection equipment when receiving the combinational logic central control command.
  • the ultraviolet device 343 disinfects the sample detection equipment when receiving the combinational logic central control command.
  • the figure only shows an indicator light control board 1343 and an ultraviolet device 1344, and does not show the connection relationship between the fourth power supply control board 1341 and the control indicator light, the laminar flow purification device 1342 and the ultraviolet device 1344, nor does it show the connection relationship between the indicator light control board 1343 and the control indicator light.
  • the central control device 1200 is a functional central control device
  • the functional central control device includes a central control board 1240 and other devices, and other devices are set according to actual functional requirements and are not limited here.
  • FIG. 12 shows a second structural schematic diagram of a control device for a sample detection device provided in the fourth embodiment of the present application.
  • control device 1000 further includes an emergency stop control panel 1400, and the emergency stop control panel 1400 is connected to the central control panel 1240;
  • the central control panel 1240 is used to adjust the operating state of the sample detection equipment according to the state of the emergency stop control panel 1400.
  • the emergency stop control panel 1400 is an emergency stop button
  • the central control panel 1240 adjusts the operating state of the sample detection device according to the state of the emergency stop control panel 1400, wherein the operating state of the sample detection device includes a working state and a stopped working state.
  • the operating state of the sample detection device is the working state, and the state of the emergency stop control panel 1400 is not the pressed state
  • the sample detection device remains in the operating state.
  • the central control panel 1240 switches the sample detection device from the working state to the stopped working state.
  • the central control device 1200 further includes an extraction device 1250 , and the extraction device 1250 is connected to the main control device 1100 ;
  • the extraction device 1250 is used to extract the nucleic acid solution in response to the received main control instruction.
  • the central control device 1200 can be equivalent to a device including a driving device 1300, that is, the central control device 1200 can be not connected to the driving device 1300.
  • the central control device 1200 also includes an extraction device 1250, and the extraction device 1250 is connected to the main control device 1100, and is not connected to the driving device 1300.
  • the main control device 1100 sends a main control instruction to each central control device 1200
  • the extraction device 1250 responds to the main control instruction
  • the central control device 1200 other than the extraction device 1250 does not respond to the main control instruction.
  • the extraction device 1250 responds to the main control instruction, performs the action of removing and removing the magnetic rod cover, the action of cell lysis, the action of adsorbing and transferring nucleic acids, and the action of washing and purifying nucleic acids, and then controls the sample detection device to perform the sample detection process.
  • the type of the extraction device 1250 is set according to actual needs and is not limited here.
  • the extraction device 1250 is a semi-automatic extraction device. It should be understood that when the central control device 1200 is an extraction central control device, the extraction central control device includes a central control panel 1240 and other devices, and the other devices are set according to the actual extraction sub-process and are not limited here.
  • the central control device 1200 further includes a plurality of detection devices 1260 , each of which is connected to the main control device 1100 ;
  • the detection device 1260 is used to respond to the received main control instruction, obtain sample detection data, and send the sample detection data to the main control device 1100;
  • the main control device 1100 is also used to generate sample detection results based on the sample detection data.
  • the central control device 1200 also includes a detection device 1260, and the detection device 1260 is connected to the main control device 1100, and is not connected to the drive device 1300.
  • the main control device 1100 sends a main control instruction to each central control device 1200, the detection device 1260 responds to the main control instruction, and the central control device 1200 other than the detection device 1260 does not respond to the main control instruction.
  • the detection device 1260 performs nucleic acid amplification to obtain sample detection data, and the sample detection data is sent to the main control device 1100.
  • the main control device 1100 generates a sample detection result based on the sample detection data. It should be understood that the number of detection devices 1260 is set according to actual needs and is not limited here.
  • the type of detection device 1260 is also set according to actual needs and is not limited here.
  • the detection device 1260 in the embodiment of the present application is a PCR detection device, and only one detection device 1260 is shown in the figure.
  • the detection device 1260 directly responds to the received main control instruction and executes the action of obtaining the sample detection data, and the detection device 1260 is not connected to the driving device 1300.
  • the central control device 1200 is a detection central control device
  • the detection central control device includes a central control board 1240 and other devices, and the other devices are set according to the actual detection sub-process and are not limited here.
  • the central control device 1200 further includes a communication device 1270 , and the communication device 1270 is connected to the main control device 1100 ;
  • the communication device 1270 is used to upload the operation status data of the sample detection device.
  • the communication device 1270 is used to communicate with external devices and upload the operating status data of the sample detection device. It should be understood that the communication device 1270 can be used to receive remote control instructions from external devices and send the remote control instructions to the main control device 1100 to remotely control the sample detection device. The communication device 1270 can also be used to upload sample detection results to external devices.
  • the type of the communication device 1270 is set according to actual needs and is not limited here.
  • the communication device 1270 is an AIOT (Artificial Intelligence & Internet of Things) device.
  • the communication device 1270 directly performs the action of uploading the operating status data of the sample detection device, and the communication device 1270 is connected to the drive device 1300.
  • the present application provides a control device for a sample detection device, in which a main control device controls a central control device and the central control device controls a driving device, thereby simplifying the main control instructions and structure of the main control device, reducing the probability of abnormalities in the sample detection device, and ensuring that the sample detection device is effectively At the same time, when an abnormality occurs in the sample detection device, only the abnormal device needs to be replaced, and there is no need to replace the main control device, central control device and drive device together.
  • the embodiment of the present application further provides a sample detection device, including the control device 1000 used for the sample detection device in the embodiment.
  • the sample detection equipment also includes an execution device.
  • the type of the execution device is set according to the needs, and can be a robotic arm, a gun tip discarding device, a plunger removal device, a feeding device, a feeding device, a cabin opening device and other equipment, which will not be described in detail here.
  • the drive device 1300 when the drive device 1300 is not connected to the execution device, the drive device 1300 responds to the instruction and directly executes the action of the detection process.
  • the drive device 1300 drives the execution device to execute the action of the detection process. Whether the drive device 1300 is connected to the execution device is set according to the actual needs of the drive device 1300, which will not be described in detail here.
  • An embodiment of the present application further provides a computer device, the computer device comprising a memory and a processor, the memory storing a computer program, and when the computer program is executed by the processor, the control method for the sample detection device as described above is implemented.
  • the embodiment of the present application further provides a computer-readable storage medium, on which a computer program is stored.
  • a computer program is stored on which a computer program is stored.
  • the embodiments of the present application may be provided as methods, systems, or computer program products. Therefore, the present application may adopt the form of a complete hardware embodiment, a complete software embodiment, or an embodiment in combination with software and hardware. Moreover, the present application may adopt the form of a computer program product implemented in one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) that include computer-usable program code.
  • a computer-usable storage media including but not limited to disk storage, CD-ROM, optical storage, etc.
  • These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing device to work in a specific manner, so that the instructions stored in the computer-readable memory produce a manufactured product including an instruction device that implements the functions specified in one or more processes in the flowchart and/or one or more boxes in the block diagram.
  • These computer program instructions may also be loaded onto a computer or other programmable data processing device so that a series of operational steps are executed on the computer or other programmable device to produce a computer-implemented process, whereby the instructions executed on the computer or other programmable device provide steps for implementing the functions specified in one or more processes in the flowchart and/or one or more boxes in the block diagram.
  • a computing device includes one or more processors (CPU), input/output interfaces, network interfaces, and memory.
  • processors CPU
  • input/output interfaces network interfaces
  • memory volatile and non-volatile memory
  • Memory may include non-permanent storage in a computer-readable medium, random access memory (RAM) and/or non-volatile memory in the form of read-only memory (ROM) or flash memory (flash RAM). Memory is an example of a computer-readable medium.
  • RAM random access memory
  • ROM read-only memory
  • flash RAM flash memory
  • Computer readable storage media include permanent and non-permanent, removable and non-removable media that can be implemented by any method or technology to store information.
  • Information can be computer readable instructions, data structures, program modules or other data.
  • Examples of computer storage media include, but are not limited to, phase change memory (PRAM), static random access memory (SRAM), dynamic random access memory (DRAM), other types of random access memory (RAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), flash memory or other memory technology, compact disk read-only memory (CD-ROM), digital versatile disk (DVD) or other optical storage, magnetic cassettes, magnetic tape magnetic disk storage or other magnetic storage devices or any other non-transmission media that can be used to store information that can be accessed by a computing device.
  • computer readable media does not include temporary computer readable media (transitory media), such as modulated data signals and carrier waves.

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Abstract

提供一种用于样本检测设备的控制方法、样本检测设备及存储介质，涉及设备控制领域。样本检测设备包括主控制装置、多个中控装置及多个驱动装置，用于样本检测设备的控制方法包括：利用主控制装置基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置；利用目标中控装置解析主控指令，生成组合逻辑中控指令，并将组合逻辑中控指令发送至目标驱动装置；利用目标驱动装置响应组合逻辑中控指令，执行检测流程的动作。

Description

用于样本检测设备的控制方法、样本检测设备及存储介质
相关申请的交叉引用
本申请要求2023年5月22日提交的中国专利申请202310580606.6、202310579473.0及202321246461.8的权益，本申请的内容通过引用被合并于本文。
技术领域
本发明涉及设备控制领域，具体地涉及一种用于样本检测设备的控制方法、样本检测设备及存储介质。
背景技术
聚合酶链式反应(Polymerase Chain Reaction，PCR)技术是一种用于放大扩增特定的脱氧核糖核酸(DeoxyriboNucleic Acid，DNA)片段的分子生物技术。目前PCR技术在基因诊断、疾病诊断等生物学样本检测领域得到了广泛应用。基于PCR技术的样本检测设备进行样本检测时，样本检测设备的操作步骤繁杂，且需要操作者远离样本检测设备。基于PCR技术的样本检测设备通常包括一个控制设备和多个执行设备，其中，执行设备为机械臂及电夹爪等设备。控制设备用于控制执行设备执行抓取试管及摇晃试管等动作，以便于操作者在远离样本检测设备的情况下进行样本检测。
然而，样本检测设备中包括大量的执行器件，需要控制设备同时控制多个执行器件。控制设备需要集成多个控制功能，导致了控制设备的指令复杂化和结构复杂化。由于控制设备需要同时发送大量的指令，要求样本检测设备的整机流程响应时间短。控制设备的指令复杂化导致控制设备的指令存在控制延时，导致样本检测设备进行样本检测容易出现异常，进而无法得到有效的样本检测结果。此外，样本检测设备的控制设备通常为多个控制功能集成的控制芯片，当控制芯片一个控制功能发生异常时，则需要更换整个控制设备，不便于进行维护。控制设备的指令复杂化和结构复杂化，增加了样本检测设备运行时发生异常的概率，进而容易导致无法得到有效的样本检测结果。
发明内容
本发明实施例的目的是提供一种用于样本检测设备的控制方法、样本检测设备及存储介质，用于样本检测设备的控制方法用于解决样本检测设备的控制设备的指令复杂化和结构复杂化，导致无法得到有效的样本检测结果的问题。
为了实现上述目的，第一方面，本申请提供一种用于样本检测设备的控制方法，样本检测设备包括主控制装置、多个中控装置及多个驱动装置，用于样本检测设备的控制方法包括：
利用主控制装置基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置，其中，主控指令用于控制目标中控装置执行检测流程，目标中控装置为可解析主控指令的中控装置；
利用目标中控装置解析主控指令，生成组合逻辑中控指令，并将组合逻辑中控指令发送至目标驱动装置，其中，目标驱动装置为与目标中控装置连接的驱动装置；
利用目标驱动装置响应组合逻辑中控指令，执行检测流程的动作。
第二方面，本申请提供一种样本检测设备，样本检测设备包括主控制装置、多个中控装置及多个驱动装置；
主控制装置，用于基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置，其中，主控指令用于控制目标中控装置执行检测流程，目标中控装置为可解析主控指令的中控装置；
目标中控装置，用于解析主控指令，生成组合逻辑中控指令，并将组合逻辑中控指令发送至目标驱动装置，其中，目标驱动装置为与目标中控装置连接的驱动装置；
目标驱动装置，用于响应组合逻辑中控指令，执行检测流程的动作。
第三方面，本申请提供一种计算机可读存储介质，计算机可读存储介质上存储有计算机程序，计算 机程序被处理器执行时，实现上述的用于样本检测设备的控制方法。
通过上述方案，由主控制装置控制中控装置并由中控装置控制驱动装置，简化了主控装置的主控指令和结构，降低样本检测设备出现异常的概率，保证样本检测设备得到有效的样本检测结果。同时，当样本检测设备发生异常时，只需要更换发生异常的装置，不需要连同主控制装置、中控装置及驱动装置一并进行更换。
附图说明
附图是用来提供对本发明实施例的进一步理解，并且构成说明书的一部分，与下面的具体实施方式一起用于解释本发明实施例，但并不构成对本发明实施例的限制。在附图中：
图1示出了本申请实施例一提供的用于样本检测设备的控制方法的流程图；
图2示出了本申请实施例一提供的样本检测设备的结构示意图；
图3示出了本申请实施例二提供的用于样本检测设备的控制方法的流程图；
图4示出了本申请实施例二提供的样本检测设备的结构示意图；
图5示出了本申请实施例三提供的用于样本检测设备的控制方法的流程图；
图6示出了本申请实施例三提供的样本检测设备的结构示意图；
图7示出了本申请实施例四提供的用于样本检测设备的控制设备的第一种结构示意图；
图8示出了本申请实施例四提供的开合盖控制板的结构示意图；
图9示出了本申请实施例四提供的移液控制板的结构示意图；
图10示出了本申请实施例四提供的送样控制板的结构示意图；
图11示出了本申请实施例四提供的中控控制板的结构示意图；
图12示出了本申请实施例四提供的用于样本检测设备的控制设备的第二种结构示意图；
附图标记说明：
200-样本检测设备；210-主控制装置、220-中控装置、230-驱动装置。400-样本检测设备；410-主控
制装置、420-中控装置、430-驱动装置；421-开合盖中控装置、422-移液中控装置、423-提取中控装置。600-样本检测设备；610-主控制装置、620-中控装置、630-驱动装置；621-送样中控装置、622-检测中控装置。1000-控制设备；1100-主控制装置、1200-中控装置、1300-驱动装置、1400-急停控制板；1210-开合盖控制板、1220-移液控制板、1230-送样控制板、1240-中控控制板、1250-提取装置、1260-检测装置、1270-通信装置；1311-扫码器、1312-第一供电控制板、1313-开合盖电机控制板、1314-第一夹爪、1315-第二夹爪、1321-第二供电控制板、1322-枪头丢弃门电机控制板、1323-移液泵、1324-移液电机控制板、1325-脱柱塞电机控制板、1331-第三夹爪、1332-第三供电控制板、1333-进料门电机控制板、1334-卡盒丢弃门电机控制板、1335-送料电机控制板、1336-送样臂电机控制板、1337-开仓电机控制板、1341-第四供电控制板、1342-层流净化装置、1343-指示灯控制板、1344-紫外装置。
具体实施方式
下面将结合本申请实施例中附图，对本申请实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本申请一部分实施例，而不是全部的实施例。
通常在此处附图中描述和示出的本申请实施例的组件可以以各种不同的配置来布置和设计。因此，以下对在附图中提供的本申请的实施例的详细描述并非旨在限制要求保护的本申请的范围，而是仅仅表示本申请的选定实施例。基于本申请的实施例，本领域技术人员在没有做出创造性劳动的前提下所获得的所有其他实施例，都属于本申请保护的范围。
在下文中，可在本申请的各种实施例中使用的术语“包括”、“具有”及其同源词仅意在表示特定特征、数字、步骤、操作、元件、组件或前述项的组合，并且不应被理解为首先排除一个或更多个其它特征、数字、步骤、操作、元件、组件或前述项的组合的存在或增加一个或更多个特征、数字、步骤、操作、 元件、组件或前述项的组合的可能性。
此外，术语“第一”、“第二”、“第三”等仅被配置为区分描述，而不能理解为指示或暗示相对重要性。
除非另有限定，否则在这里使用的所有术语(包括技术术语和科学术语)具有与本申请的各种实施例所属领域普通技术人员通常理解的含义相同的含义。所述术语(诸如在一般使用的词典中限定的术语)将被解释为具有与在相关技术领域中的语境含义相同的含义并且将不被解释为具有理想化的含义或过于正式的含义，除非在本申请的各种实施例中被清楚地限定。
实施例一
请参阅图1，图1示出了本申请实施例一提供的用于样本检测设备的控制方法的流程图。样本检测设备包括主控制装置、多个中控装置及多个驱动装置，图1中的用于样本检测设备的控制方法包括：
S110，利用主控制装置基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置。
请参阅图2，图2示出了本申请实施例一提供的样本检测设备的结构示意图。
样本检测设备200包括主控制装置210、多个中控装置220及多个驱动装置230。为便于理解，图中仅示出了1个中控装置220和1个驱动装置230。
主控制装置210获取样本的检测流程，其中，样本的检测流程是根据实际需求设置的，在此不做限定。样本的检测流程可直接存储于主控制装置210，同时，样本检测设备也可以与外部设备连接，通过外部设备将样本的检测流程发送至主控制装置210，进而通过外部设备对样本检测设备进行远程控制。
主控制装置210将主控指令发送至每个中控装置220，其中，主控指令用于控制目标中控装置执行检测流程，目标中控装置为可解析主控指令的中控装置220。所有的中控装置220均接收主控指令，仅目标中控装置响应主控指令并控制驱动装置230，保证了样本检测设备200基于样本的检测流程进行检测。主控制装置210控制中控装置220的运行，以通过中控装置220控制驱动装置230，简化了主控制装置210的主控指令，降低了指令延时过长等异常情况的出现概率，使得样本检测设备200能够得到有效的样本检测结果。
本申请的实施例中，主控指令包括开合盖子流程的主控指令、移液子流程的主控指令、提取子流程的主控指令、送样子流程的主控指令及检测子流程的主控指令。
主控制装置将样本的检测流程，确定为多个子流程，并对于每个子流程生成主控指令。为便于理解，本申请的实施例中样本的检测流程确定为开合盖子流程、移液子流程、提取子流程、送样子流程、检测子流程等多个子流程。主控指令对应包括开合盖子流程的主控指令、移液子流程的主控指令、提取子流程的主控指令、送样子流程的主控指令及检测子流程的主控指令。
S120，利用目标中控装置解析主控指令，生成组合逻辑中控指令，并将组合逻辑中控指令发送至目标驱动装置。
样本检测设备在进行样本检测的过程中，主控指令用于控制中控装置，使得中控装置控制驱动装置执行样本的检测流程的动作。组合逻辑中控指令用于控制驱动装置执行样本的检测流程的动作。主控装置只需要通过主控指令控制中控装置的运行，实现了主控装置的指令简化。具体地，主控制装置将主控指令发送至每个中控装置之后，目标中控装置响应主控指令。中控装置为可解析主控指令的中控装置，确定需要所有目标驱动装置共同执行的组合动作，其中，目标驱动装置为与目标中控装置连接的驱动装置。
目标中控装置基于组合动作，生成组合逻辑中控指令，并将组合逻辑中控指令发送至目标驱动装置。具体地，通常一个目标中控装置连接至少一个目标驱动装置。以样本的检测流程的移液子流程为例，目标中控装置需控制目标驱动装置执行取枪头动作、吸液动作、注液动作及脱枪头动作等多个动作组成的组合动作。目标中控装置通过组合逻辑中控指令，控制目标驱动装置共同完成组合动作，以完成样本的检测流程的一个子流程。主控制装置将主控指令发送至多个中控装置，目标中控装置响应主控指令，目标中控装置以外的中控装置不响应主控指令，即使指令的传输和响应存在延时，样本检测设备仍能够依次完成检测流程的每个子流程，进而使得样本检测设备能够基于样本的检测流程进行检测。
S130，利用目标驱动装置响应组合逻辑中控指令，执行检测流程的动作。
本申请的实施例中，由每个中控装置确定是否响应，生成样本的检测流程对应的组合逻辑中控指令。目标驱动装置接收到组合逻辑中控指令之后，目标驱动装置直接响应组合逻辑中控指令，并执行检测流程的动作。驱动装置不需要确定是否响应主控制装置发送的指令，而是可直接执行动作，避免了主控制装置的指令未被驱动装置正确响应，保证了样本检测设备能够基于样本的检测流程进行检测。由于主控制装置、多个中控装置及多个驱动装置没有集成为一个集成化的装置，当样本检测设备发生异常时，只需要更换发生异常的装置。举例而言，当其中一个中控装置发生异常时，只需要更换发生异常的中控装置，不需要连同主控制装置、中控装置及驱动装置一并进行更换。
作为一个示例，用于样本检测设备的控制方法还包括：
在目标驱动装置完成动作的情况下，利用目标驱动装置生成动作完成信号，并将动作信号发送至目标中控装置；
利用目标中控装置根据动作完成信号，检测是否完成主控指令；
在未完成主控指令的情况下，利用目标中控装置将组合逻辑中控指令发送至下一个目标驱动装置。
为便于理解，以样本的检测流程的移液子流程为例，需要目标中控装置依次将组合逻辑中控指令发送至每个目标驱动装置，以控制多个目标驱动装置共同执行移液子流程的组合动作。具体地，目标中控装置将组合逻辑中控指令发送至目标驱动装置，目标驱动装置执行完成取枪头动作之后，目标驱动装置生成动作完成信号，并将动作信号发送至目标中控装置。
目标中控装置根据动作完成信号，检测是否完成主控指令。目标中控装置根据移液子流程的主控指令，确定移液子流程的组合动作。目标中控装置根据动作完成信号，确定已完成的移液子流程动作为取枪头动作，不为组合动作的最后一个动作，则确定中控装置未完成主控指令。目标中控装置将组合逻辑中控指令发送至下一个目标驱动装置，控制下一个目标驱动装置执行吸液动作。
在完成的移液子流程动作为组合动作的最后一个动作的情况下，则确定中控装置已完成主控指令未完成主控指令。相对于中控装置直接将指令发送至所有的驱动装置，中控装置根据动作完成信号依次将指令发送至每个驱动装置，即使指令的传输和响应存在延时，样本检测设备也不会提前执行下一个检测流程的动作，保证了样本检测设备能够基于样本的检测流程进行检测。
作为一个示例，用于样本检测设备的控制方法还包括：
利用主控制装置获取中控装置生成的指令完成信号，并基于指令完成信号确定是否完成样本检测；
在未完成样本检测的情况下，执行利用主控制装置基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置的步骤。
中控装置根据驱动装置发送的动作完成信号，确定完成主控指令之后，生成指令完成信号，并将指令完成信号发送至主控制装置。主控制装置基于指令完成信号确定是否完成样本检测，具体地，主控制装置基于指令完成信号确定已完成的子流程，并确定已完成的子流程是否为检测流程的最后一个流程。在已完成的子流程为检测流程的最后一个流程的情况下，则确定完成样本检测。
在已完成的子流程不为检测流程的最后一个流程的情况下，则确定未完成样本检测。主控制装置基于样本的检测流程，确定下一个子流程。主控制装置生成下一个子流程的主控指令，并将下一个子流程的主控指令发送至每个中控装置。重复执行利用主控制装置基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置的步骤，直到样本检测设备完成样本的检测流程所有子流程，使得样本检测设备能够基于样本的检测流程进行检测。
作为一个示例，中控装置包括功能中控装置，利用目标中控装置解析主控指令，生成组合逻辑中控指令，并将组合逻辑中控指令发送至目标驱动装置，包括：
在目标中控装置为功能中控装置的情况下，利用功能中控装置解析主控指令，生成第五组合逻辑中控指令，并将第五组合逻辑中控指令依次发送至每个目标驱动装置，其中，第五组合逻辑中控指令用于控制目标驱动装置执行调整检测环境的组合动作。
在目标中控装置为功能中控装置的情况下，功能中控装置响应主控指令，且功能中控装置以外的中控装置不响应主控指令。利用功能中控装置解析主控指令，生成第五组合逻辑中控指令，以控制目标驱动 装置执行调整检测环境的组合动作，其中，调整检测环境的组合动作包括调整温度动作、排风动作等，在此不做赘述。
本申请的实施例中，目标驱动装置包括排风装置和温度控制装置。目标中控装置依次将第五组合逻辑中控指令依次发送至每个目标驱动装置。排风装置响应组合逻辑中控指令，执行排风动作；温度控制装置响应组合逻辑中控指令，执行调整动作，进而调整样本检测设备的检测环境，避免样本被污染。
本申请提供一种用于样本检测设备的控制方法，由中控装置控制驱动装置，驱动装置接收到中控装置指令之后直接执行检测动作。驱动装置不再需要确定是否响应接收到的指令，避免了主控制装置的指令未被驱动装置正确响应，保证了样本检测设备能够基于样本的检测流程进行检测。
实施例二
请参阅图3，图3示出了本申请实施例二提供的用于样本检测设备的控制方法的流程图。样本检测设备包括主控制装置、多个中控装置及多个驱动装置，图3中的用于样本检测设备的控制方法包括：
S310，利用主控制装置基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置。
请参阅图4，图4示出了本申请实施例二提供的样本检测设备的结构示意图。
本申请的实施例中，样本检测设备400中的中控装置420包括开合盖中控装置421、移液中控装置422及提取中控装置423。主控制装置410基于样本的检测流程，生成主控指令，并将主控指令发送至开合盖中控装置421、移液中控装置422及提取中控装置423。为便于理解，图中仅示出一个连接开合盖中控装置421的驱动装置430，一个连接移液中控装置422的驱动装置430，一个连接提取中控装置423的驱动装置430。
通常进行样本检测时，需要得到提纯后的核酸液。将提纯后的核酸液与检测试剂注入试剂卡盒，得到待检测的试剂卡盒。为便于理解，本申请的实施例中样本检测设备用于得到待检测的试剂卡盒。基于待检测的试剂卡盒，得到样本检测结果的步骤，在此不做赘述。样本的检测流程包括开盖子流程、吸取试剂子流程、合盖子流程、提取核酸子流程及混合试剂子流程。
主控制装置410基于样本的检测流程，生成开盖子流程的主控指令、吸取试剂子流程的主控指令、合盖子流程的主控指令、提取核酸子流程的主控指令及混合试剂子流程的主控指令，并依次将每个主控指令发送至开合盖中控装置421、移液中控装置422及提取中控装置423。
S321，在目标中控装置为开合盖中控装置的情况下，利用开合盖中控装置解析主控指令，生成第一组合逻辑中控指令，并将第一组合逻辑中控指令依次发送至每个目标驱动装置。
主控制装置生成开盖子流程的主控指令，并将开盖子流程的主控指令发送至每个中控装置之后，目标中控装置响应主控指令，移液中控装置和提取中控装置不响应主控指令，即目标中控装置为开合盖中控装置。
利用开合盖中控装置解析主控指令，生成第一组合逻辑中控指令，其中，解析开盖子流程的主控指令生成的第一组合逻辑中控指令，用于控制目标驱动装置执行开盖的组合动作。开合盖中控装置将第一组合逻辑中控指令依次发送至开盖子流程对应的每个目标驱动装置，控制多个目标驱动装置共同执行开盖的组合动作，其中，开盖的组合动作包括抓取试管动作、打开试管盖动作。
为便于理解，以目标中控装置控制目标驱动装置执行开盖的组合动作为例，每个目标驱动装置执行一个动作，即一个目标驱动装置执行抓取试管动作，另一个目标驱动装置执行打开试管盖动作，进而通过两个目标驱动装置共同执行开盖的组合动作。
S322，在目标中控装置为移液中控装置的情况下，利用移液中控装置解析主控指令，生成第二组合逻辑中控指令，并将第二组合逻辑中控指令依次发送至每个目标驱动装置。
开盖子流程完成之后，主控制装置响应指令完成信号，将吸取试剂子流程主控指令发送至每个中控装置，响应主控指令的目标中控装置为移液中控装置。利用目标中控装置解析主控指令，生成第二组合逻辑中控指令，其中，解析吸取试剂子流程的主控指令生成的第二组合逻辑中控指令，用于控制目标驱动装置执行吸取试剂的组合动作。
目标中控装置将第二组合逻辑中控指令依次发送至吸取试剂子流程对应的每个目标驱动装置，控制 多个目标驱动装置共同执行吸取试剂的组合动作，其中，吸取试剂的组合动作包括取枪头动作、吸取检测样本并注入深孔板动作。
吸取试剂子流程完成之后，主控制装置响应指令完成信号，将合盖子流程的主控指令发送至每个中控装置，响应主控指令的目标中控装置为开合盖中控装置。利用目标中控装置解析主控指令，生成第一组合逻辑中控指令，其中，解析合盖子流程的主控指令生成的第一组合逻辑中控指令，用于控制目标驱动装置执行合盖的组合动作。
目标中控装置将第一组合逻辑中控指令依次发送至合盖子流程对应的每个目标驱动装置，控制多个目标驱动装置共同执行合盖的组合动作，其中，合盖的组合动作包括关闭试管盖动作、将试管放入载架动作。
S323，在目标中控装置为提取中控装置的情况下，利用提取中控装置解析主控指令，生成第三组合逻辑中控指令，并将第三组合逻辑中控指令依次发送至每个目标驱动装置。
完成需求数量的样本采集之后，主控制装置响应指令完成信号，将提取核酸子流程的主控指令发送至每个中控装置，响应主控指令的目标中控装置为移液中控装置。利用目标中控装置解析主控指令，生成第三组合逻辑中控指令，其中，解析提取核酸子流程的主控指令生成的第三组合逻辑中控指令，用于控制目标驱动装置执行提取核酸的组合动作。
目标中控装置将第三组合逻辑中控指令依次发送至提取核酸子流程对应的每个目标驱动装置，控制多个目标驱动装置共同执行提取核酸的组合动作，其中，提取核酸的组合动作包括取脱磁棒套动作、细胞裂解动作、吸附转移核酸动作及洗涤提纯核酸动作。
提取核酸子流程完成之后，主控制装置响应指令完成信号，将混合试剂子流程的主控指令发送至每个中控装置，响应主控指令的目标中控装置为开合盖中控装置。利用目标中控装置解析主控指令，生成第二组合逻辑中控指令，其中，解析混合试剂子流程的主控指令生成的第二组合逻辑中控指令，用于控制目标驱动装置执行混合试剂的组合动作。
目标中控装置将第二组合逻辑中控指令依次发送至混合试剂子流程对应的每个目标驱动装置，控制多个目标驱动装置共同执行混合试剂的组合动作，其中，混合试剂的组合动作包括脱枪头动作、脱柱塞动作、提纯后的核酸液与检测试剂注入试剂卡盒动作。混匀试剂卡盒动作及压柱塞动作。
S330，利用目标驱动装置响应组合逻辑中控指令，执行检测流程的动作。
目标驱动装置直接响应组合逻辑中控指令，并执行检测流程的一个动作。将样本的检测流程分为多个动作，每个驱动装置执行一个动作，得到检测流程的组合动作，进而得到待检测的试剂卡盒。
实施例三
请参阅图5，图5示出了本申请实施例三提供的用于样本检测设备的控制方法的流程图。样本检测设备包括主控制装置、多个中控装置及多个驱动装置，图5中的用于样本检测设备的控制方法包括：
S510，利用主控制装置基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置。
请参阅图6，图6示出了本申请实施例三提供的样本检测设备的结构示意图。
本申请的实施例中，样本检测设备600中的中控装置620包括送样中控装置621和检测中控装置622。主控制装置610基于样本的检测流程，生成主控指令，并将主控指令发送至送样中控装置621和检测中控装置622。为便于理解，图中仅示出一个连接送样中控装置621的驱动装置630，一个连接检测中控装置622的驱动装置630。
通常进行样本检测时，得到待检测的试剂卡盒之后，对试剂卡盒进行检测，得到样本检测结果。为便于理解，本申请的实施例中样本检测设备用于得到样本检测结果。样本的检测流程包括送样子流程和检测子流程。主控制装置610基于样本的检测流程，生成送样子流程的主控指令及检测子流程的主控指令，并依次将每个主控指令发送至送样中控装置621和检测中控装置622。
S521，在目标中控装置为送样中控装置的情况下，利用送样中控装置解析主控指令，生成第四组合逻辑中控指令，并将第四组合逻辑中控指令依次发送至每个目标驱动装置。
获取到待检测的试剂卡盒之后，主控制装置响应指令完成信号，将送样子流程的主控指令发送至每 个中控装置，响应主控指令的目标中控装置为送样中控装置。利用目标中控装置解析主控指令，生成第四组合逻辑中控指令，其中，解析送样子流程的主控指令生成的第四组合逻辑中控指令，用于控制目标驱动装置执行送样的组合动作。
目标中控装置将第四组合逻辑中控指令依次发送至送样子流程对应的每个目标驱动装置，控制多个目标驱动装置共同执行送样的组合动作，其中，送样的组合动作包括打开检测位置舱门动作、转移试剂卡盒至检测位置动作、关闭检测位置舱门动作、打开检测卡盒动作、试剂卡盒插入检测位动作及关闭检测卡盒动作。
S522，在目标中控装置为检测中控装置的情况下，利用检测中控装置解析主控指令，生成第六组合逻辑中控指令，并将第六组合逻辑中控指令依次发送至每个目标驱动装置。
完成送样子流程之后，主控制装置响应指令完成信号，将检测子流程的主控指令发送至每个中控装置，响应主控指令的目标中控装置为检测中控装置。利用目标中控装置解析主控指令，生成第六组合逻辑中控指令，其中，解析检测子流程的主控指令生成的第六组合逻辑中控指令，用于控制目标驱动装置执行获取样本检测数据的组合动作。
目标中控装置将第六组合逻辑中控指令依次发送至检测子流程对应的每个目标驱动装置，控制多个目标驱动装置共同执行获取样本检测数据的组合动作，其中，获取样本检测数据的组合动作包括核酸扩增动作和独取样本检测数据。需要理解的是，本申请的实施例中第一组合逻辑中控指令、第二组合逻辑中控指令、第三组合逻辑中控指令、第四组合逻辑中控指令、第五组合逻辑中控指令及第六组合逻辑中控指令，仅用于区分描述，而不能理解为指示或暗示相对重要性。
作为一个示例，用于样本检测设备的控制方法还包括：
利用主控制装置获取检测中控装置得到的样本检测数据，并基于样本检测数据生成样本检测结果。
检测中控装置将获取到的样本检测数据发送至主控制装置，主控制装置基于样本检测数据生成样本检测结果。需要理解的是，中控装置可以通过控制板等实现，在此不做赘述。在驱动装置可直接响应主控制装置的指令的情况下，可将驱动装置视为包括中控装置的设备。为便于理解，本申请的实施例中样本检测设备包括PCR样本检测设备。
S530，利用目标驱动装置响应组合逻辑中控指令，执行检测流程的动作。
目标驱动装置直接响应组合逻辑中控指令，并执行检测流程的一个动作。将样本的检测流程分为多个动作，每个驱动装置执行一个动作，得到检测流程的组合动作，进而得到样本检测结果。
实施例四
请参阅图7，图7示出了本申请实施例四提供的用于样本检测设备的控制设备的第一种结构示意图。
控制设备1000用于控制样本检测设备，控制设备1000包括：主控制装置1100、多个中控装置1200及多个驱动装置1300；
每个中控装置1200的一端连接主控制装置1100，且另一端连接至少一个驱动装置1300；
主控制装置1100，用于基于样本的检测流程，生成主控指令，并将主控指令发送至每个中控装置1200，其中，主控指令用于控制中控装置1200执行检测流程；
中控装置1200，用于解析主控指令，生成组合逻辑中控指令，并将组合逻辑中控指令发送至驱动装置1300；
驱动装置1300，用于响应组合逻辑中控指令，执行检测流程的动作。
每个中控装置1200的一端连接主控制装置1100，且中控装置1200的另一端连接至少一个驱动装置1300。主控制装置1100与中控装置1200之间的连接方式是根据实际需求设置的，可以是RS(Recommended Standard，推荐标准)232总线连接，也可以是CAN总线连接，在此不做限定。驱动装置1300与中控装置1200之间的连接方式也是根据实际需求设置的，在此不做限定。中控装置1200和驱动装置1300的数量是根据实际需求设置，每个中控装置1200连接的驱动装置1300的数量也是根据实际需求设置的，在此不做限定。为便于理解，图中仅示出了两个中控装置1200和四个驱动装置1300，每个中控装置1200连接两个驱动装置1300。
主控制装置1100将样本的检测流程，确定为多个子流程，并对于每个子流程生成主控指令。为便于理解，本申请的实施例中样本的检测流程由开合盖子流程、移液子流程、提取子流程、送样子流程、检测子流程等多个子流程组成。控制设备1000包括多个中控装置1200，每个中控装置1200用于控制驱动装置1300执行至少一个子流程的动作。在进行开合盖子流程的情况下，响应开合盖子流程的主控指令的中控装置1200为目标中控装置；在进行提取子流程的情况下，响应提取子流程的主控指令的中控装置1200为目标中控装置，其余的子流程的目标中控装置在此不做赘述。主控制装置1100将主控指令发送至每个中控装置1200，目标中控装置响应主控指令，解析主控指令确定检测流程的子流程。中控装置1200检测流程的子流程，确定为多个动作，并根据子流程的多个动作执行顺序，生成组合逻辑中控指令。主控制装置1100控制中控装置1200的运行，以通过中控装置1200控制驱动装置1300，简化了主控制装置1100的主控指令，降低了指令延时过长等异常情况的出现概率，使得样本检测设备能够得到有效的样本检测结果。
目标中控装置基于多个动作执行顺序，依次将每个组合逻辑中控指令发送至每个目标驱动装置1300，其中，目标驱动装置1300为连接目标中控装置的目标驱动装置1300。通过组合逻辑中控指令控制每个驱动装置1300执行检测流程的一个动作，进而通过多个驱动装置1300共同完成检测流程的所有动作。驱动装置1300在未接收到指令的情况下，不执行检测流程的动作。驱动装置1300在接收到指令的情况下，直接执行检测流程的动作。驱动装置1300不再需要确定是否响应接收到的指令，避免了主控制装置1100的指令未被驱动装置1300正确响应，保证了样本检测设备能够基于样本的检测流程进行检测。由于主控制装置1100、多个中控装置1200及多个驱动装置1300没有集成为一个集成化的装置，当样本检测设备发生异常时，只需要更换发生异常的装置。举例而言，当其中一个中控装置1200发生异常时，只需要更换发生异常的中控装置1200，不需要连同主控制装置1100、中控装置1200及驱动装置1300一并进行更换。
请参阅图8，图8示出了本申请实施例四提供的开合盖控制板的结构示意图。
本申请的实施例中，中控装置1200包括开合盖控制板1210，驱动装置1300包括扫码器1311、第一供电控制板1312，以及多个开合盖电机控制板1313、多个第一夹爪1314、多个第二夹爪1315；
开合盖控制板1210分别连接扫码器1311、第一供电控制板1312、开合盖电机控制板1313、第一夹爪1314及第二夹爪1315；
扫码器1311，用于获取样本试管的条码信息；
第一供电控制板1312，用于控制开合盖电机控制板1313、第一夹爪1314、第二夹爪1315的供电状态；
开合盖电机控制板1313，用于控制开合盖机械臂的电机运行状态；
第一夹爪1314，用于夹持试剂卡盒的盖帽；
第二夹爪1315，用于夹持试剂卡盒的底座。
将样本的检测流程，确定为多个子流程。在样本检测设备进行开合盖子流程的情况下，开合盖控制板1210用于响应主控制装置1100的主控指令，开合盖控制板1210以外的中控装置1200不响应主控制装置1100的主控指令。开合盖控制板1210解析主控指令，生成组合逻辑中控指令。开合盖控制板1210基于开合盖子流程的动作顺序，依次发送组合逻辑中控指令至多个驱动装置1300，其中，开合盖子流程的动作顺序是根据实际需求设置的，在此不做赘述。需要理解的是，在中控装置1200为开合盖中控装置的情况下，开合盖中控装置包括开合盖控制板1210和其他器件，其他器件是根据实际开合盖子流程设置的，在此不做限定。
通常样本检测设备需要同时对多个样本进行检测，扫码器1311在接收到组合逻辑中控指令的情况下，获取样本试管的条码信息，以区分多个样本。第一供电控制板1312在接收到组合逻辑中控指令的情况下，控制开合盖电机控制板1313、第一夹爪1314、第二夹爪1315的供电状态。开合盖电机控制板1313在接收到组合逻辑中控指令的情况下，控制开合盖机械臂的电机工作状态。第一夹爪1314在接收到组合逻辑中控指令的情况下，夹持试剂卡盒的盖帽。第二夹爪1315在接收到组合逻辑中控指令的情况下，夹持试剂卡盒的底座。通过开合盖控制板1210控制第一夹爪1314和第二夹爪1315的夹持位置、夹持力值、运行速度及旋转角度等参数，进而多个驱动设备执行夹持试管动作、试管开盖动作及试管合盖动作等开合盖子流 程的动作，进而控制样本检测设备进行样本的检测流程。
开合盖电机控制板1313、第一夹爪1314及第二夹爪1315的数量均是根据实际需求设置的，在此不做限定。为便于理解，图中仅示出一个开合盖电机控制板1313、一个第一夹爪1314及一个第二夹爪1315，且不示出第一供电控制板1312与开合盖电机控制板1313、第一夹爪1314、第二夹爪1315的连接关系。
请参阅图9，图9示出了本申请实施例四提供的移液控制板的结构示意图。
本申请的实施例中，中控装置1200包括移液控制板1220，驱动装置1300包括第二供电控制板1321、枪头丢弃门电机控制板1322，以及多个移液泵1323、多个移液电机控制板1324、多个脱柱塞电机控制板1325；
移液控制板1220分别连接第二供电控制板1321、枪头丢弃门电机控制板1322、移液泵1323、移液电机控制板1324及脱柱塞电机控制板1325；
第二供电控制板1321，用于控制枪头丢弃门电机控制板1322、移液泵1323、移液电机控制板1324及脱柱塞电机控制板1325的供电状态；
枪头丢弃门电机控制板1322，用于控制枪头丢弃装置的电机运行状态；
移液泵1323，用于吸取或排出液体；
移液电机控制板1324，用于控制移液机械臂的电机运行状态；
脱柱塞电机控制板1325，用于控制脱柱塞装置的电机运行状态。
将样本的检测流程，确定为多个子流程。在样本检测设备进行移液子流程的情况下，移液控制板1220用于响应主控制装置1100的主控指令，移液控制板1220以外的中控装置1200不响应主控制装置1100的主控指令。移液控制板1220解析主控指令，生成组合逻辑中控指令。移液控制板1220基于移液子流程的动作顺序，依次发送组合逻辑中控指令至多个驱动装置1300，其中，移液子流程的动作顺序是根据实际需求设置的，在此不做赘述。需要理解的是，在中控装置1200为移液中控装置的情况下，移液中控装置包括移液控制板1220和其他器件，其他器件是根据实际移液子流程设置的，在此不做限定。
第二供电控制板1321在接收到组合逻辑中控指令的情况下，控制枪头丢弃门电机控制板1322、移液泵1323、移液电机控制板1324及脱柱塞电机控制板1325的供电状态。枪头丢弃门电机控制板1322在接收到组合逻辑中控指令的情况下，控制枪头丢弃装置的电机工作状态。移液泵1323在接收到组合逻辑中控指令的情况下，吸取或排出液体。移液电机控制板1324在接收到组合逻辑中控指令的情况下，控制移液机械臂的电机工作状态。脱柱塞电机控制板1325在接收到组合逻辑中控指令的情况下，控制脱柱塞装置的电机工作状态。通过多个驱动设备执行吸取试剂动作、液面探测动作、排出试剂动作、取枪头动作、脱枪头动作等移液子流程的动作，进而控制样本检测设备进行样本的检测流程。
移液泵1323、移液电机控制板1324及脱柱塞电机控制板1325的数量均是根据实际需求设置的，在此不做限定。为便于理解，图中仅示出一个移液泵1323、一个移液电机控制板1324及一个脱柱塞电机控制板1325，且不示出第二供电控制板1321与枪头丢弃门电机控制板1322、移液泵1323、移液电机控制板1324及脱柱塞电机控制板1325的连接关系。
请参阅图10，图10示出了本申请实施例四提供的送样控制板的结构示意图。
本申请的实施例中，中控装置1200包括送样控制板1230，驱动装置1300包括第三夹爪1331、第三供电控制板1332、进料门电机控制板1333、卡盒丢弃门电机控制板1334，以及多个送料电机控制板1335、多个送样臂电机控制板1336、多个开仓电机控制板1337；
送样控制板1230分别连接第三夹爪1331、第三供电控制板1332、进料门电机控制板1333、卡盒丢弃门电机控制板1334、送料电机控制板1335、送样臂电机控制板1336及开仓电机控制板1337；
第三夹爪1331，用于夹持试剂卡盒；
第三供电控制板1332，用于控制第三夹爪1331的供电状态；
进料门电机控制板1333，用于控制进料装置的电机运行状态；
卡盒丢弃门电机控制板1334，用于控制卡盒丢弃装置的电机运行状态；
送料电机控制板1335，用于控制送料装置的电机运行状态；
送样臂电机控制板1336，用于控制送样机械臂的电机运行状态；
开仓电机控制板1337，用于控制开舱装置的电机运行状态。将样本的检测流程，确定为多个子流程。在样本检测设备进行送样子流程的情况下，送样控制板1230用于响应主控制装置1100的主控指令，送样控制板1230以外的中控装置1200不响应主控制装置1100的主控指令。送样控制板1230解析主控指令，生成组合逻辑中控指令。送样控制板1230基于送样子流程的动作顺序，依次发送组合逻辑中控指令至多个驱动装置1300，其中，送样子流程的动作顺序是根据实际需求设置的，在此不做赘述。需要理解的是，在中控装置1200为送样中控装置的情况下，送样中控装置包括送样控制板1230和其他器件，其他器件是根据实际送样子流程设置的，在此不做限定。
第三夹爪1331在接收到组合逻辑中控指令的情况下，夹持试剂卡盒。第三供电控制板1332在接收到组合逻辑中控指令的情况下，控制第三夹爪1331的供电状态。进料门电机控制板1333在接收到组合逻辑中控指令的情况下，控制进料装置的电机工作状态。卡盒丢弃门电机控制板1334在接收到组合逻辑中控指令的情况下，控制卡盒丢弃装置的电机工作状态。送料电机控制板1335在接收到组合逻辑中控指令的情况下，控制送料装置的电机工作状态。送样臂电机控制板1336在接收到组合逻辑中控指令的情况下，控制送样机械臂的电机工作状态。开仓电机控制板1337在接收到组合逻辑中控指令的情况下，控制开舱装置的电机工作状态。通过多个驱动设备执行打开检测位置舱门动作、转移试剂卡盒至检测位置动作、关闭检测位置舱门动作、打开检测卡盒动作、试剂卡盒插入检测位动作及关闭检测卡盒动作。等送样子流程的动作，进而控制样本检测设备进行样本的检测流程。
多个送料电机控制板1335、送样臂电机控制板1336及开仓电机控制板1337的数量均是根据实际需求设置的，在此不做限定。为便于理解，图中仅示出一个多个送料电机控制板1335、一个送样臂电机控制板1336及一个开仓电机控制板1337，且不示出第三供电控制板1332与第三夹爪1331的连接关系。
请参阅图11，图11示出了本申请实施例四提供的中控控制板的结构示意图。
本申请的实施例中，中控装置1200包括中控控制板1240，驱动装置1300包括第四供电控制板1341、层流净化装置1342、多个指示灯控制板1343及多个紫外装置1344；
中控控制板1240分别连接第四供电控制板1341、层流净化装置1342、指示灯控制板1343及所述紫外装置1344；
层流净化装置1342，用于净化所述样本检测设备内的污染物；
所述紫外装置343，用于进行所述样本检测设备的消毒；
指示灯控制板1343，用于控制指示灯的指示状态；
第四供电控制板1341，用于控制指示灯、层流净化装置1342及紫外装置1344的供电状态。
主控制装置1100还用于确定样本检测设备的工作状态。具体地，主控制装置1100接收到工作状态确定请求，生成主控指令。送样控制板1230用于响应主控制装置1100的主控指令，送样控制板1230以外的中控装置1200不响应主控制装置1100的主控指令。第四供电控制板1341控制指示灯、层流净化装置1342及紫外装置1344的供电状态。中控控制板1240根据样本检测设备的工作状态，发送指令至指示灯控制板1343和第四供电控制板1341。具体地，第四供电控制板1341用于控制指示灯的供电状态。指示灯控制板1343用于控制指示灯调整为间隔闪烁和长亮等指示状态。需要理解的是，样本检测设备可根据实际需求配置为不同的工作状态，指示灯通过不同的指示状态反馈样本检测设备的工作状态，在此不做赘述。层流净化装置1342在接收到组合逻辑中控指令的情况下，净化所述样本检测设备内的污染物。所述紫外装置343在接收到组合逻辑中控指令的情况下，进行所述样本检测设备的消毒。为便于理解，图中仅示出一个指示灯控制板1343和一个紫外装置1344，且不示出第四供电控制板1341与控制指示灯、层流净化装置1342及紫外装置1344的连接关系，也不示出指示灯控制板1343与控制指示灯的连接关系。需要理解的是，在中控装置1200为功能中控装置的情况下，功能中控装置包括中控控制板1240和其他器件，其他器件是根据实际功能需求设置的，在此不做限定。
请参阅图12，图12示出了本申请实施例四提供的用于样本检测设备的控制设备的第二种结构示意图。
本申请的实施例中，控制设备1000还包括急停控制板1400，急停控制板1400连接中控控制板1240；
中控控制板1240，用于根据急停控制板1400的状态，调整样本检测设备的运行状态。
当样本的检测流程发生异常时，用户可通过急停控制板1400，控制样本检测设备停止运行。为便于理解本申请的实施例中急停控制板1400为急停按键，中控控制板1240根据急停控制板1400的状态，调整样本检测设备的运行状态，其中，样本检测设备的运行状态包括工作状态和停止工作状态。在样本检测设备的运行状态为工作状态，且急停控制板1400的状态不为按下状态的情况下，样本检测设备保持为运行状态。在样本检测设备的运行状态为工作状态，且急停控制板1400的状态为按下状态的情况下，中控控制板1240将样本检测设备由工作状态切换为停止工作状态。
本申请的实施例中，中控装置1200还包括提取装置1250，提取装置1250连接主控制装置1100；
提取装置1250，用于响应接收到的主控指令，提取核酸液。
在中控装置1200可用于执行检测流程的动作的情况下，可将中控装置1200等效为包括驱动装置1300的设备，即中控装置1200可不连接驱动装置1300。中控装置1200还包括提取装置1250，且提取装置1250连接主控制装置1100，不连接驱动装置1300。当进行检测流程的提取子流程时，主控制装置1100发送主控指令至每个中控装置1200，提取装置1250响应主控指令，且提取装置1250以外的中控装置1200不响应主控指令。具体地，提取装置1250响应主控指令，执行取脱磁棒套动作、细胞裂解动作、吸附转移核酸动作及洗涤提纯核酸动作，进而控制样本检测设备进行样本的检测流程。需要理解的是，提取装置1250的类型是根据实际需求设置的，在此不做限定。为便于理解，本申请的实施例中，提取装置1250为半自动提取仪。需要理解的是，在中控装置1200为提取中控装置的情况下，提取中控装置包括中控控制板1240和其他器件，其他器件是根据实际提取子流程设置的，在此不做限定。
本申请的实施例中，中控装置1200还包括多个检测装置1260，每个检测装置1260均连接主控制装置1100；
检测装置1260，用于响应接收到的主控指令，获取样本检测数据，并将样本检测数据发送至主控制装置1100；
主控制装置1100，还用于根据样本检测数据，生成样本检测结果。
中控装置1200还包括检测装置1260，且检测装置1260连接主控制装置1100，不连接驱动装置1300。当进行检测流程的提取子流程时，主控制装置1100发送主控指令至每个中控装置1200，检测装置1260响应主控指令，且检测装置1260以外的中控装置1200不响应主控指令。检测装置1260进行核酸扩增，得到样本检测数据，并样本检测数据发送至主控制装置1100。主控制装置1100根据样本检测数据，生成样本检测结果。需要理解的是，检测装置1260的数量是根据实际需求设置，在此不做限定。检测装置1260的类型也是根据实际需求设置，在此不做限定。为便于理解，本申请的实施例中检测装置1260为PCR检测设备，且图中仅示出一个检测装置1260。本申请的实施例中，检测装置1260直接响应接收到的主控指令，执行获取样本检测数据的动作，检测装置1260不连接驱动装置1300。需要理解的是，在中控装置1200为检测中控装置的情况下，检测中控装置包括中控控制板1240和其他器件，其他器件是根据实际检测子流程设置的，在此不做限定。
本申请的实施例中，中控装置1200还包括通信装置1270，通信装置1270连接主控制装置1100；
通信装置1270，用于上传样本检测设备的运行状态数据。
通信装置1270用于与外部设备通信，上传样本检测设备的运行状态数据。需要理解的是，通信装置1270可以用于接收外部设备的远程控制指令，并将远程控制指令发送至主控制装置1100，以远程控制样本检测设备。通信装置1270还可以用于将样本检测结果上传至外部设备。通信装置1270的类型是根据实际需求设置的，在此不做限定。为便于理解，本申请的实施例中通信装置1270为AIOT(Artificial Intelligence&Internet of Things，人工智能物联网)设备。本申请的实施例中，通信装置1270直接执行上传样本检测设备的运行状态数据的动作，通信装置1270连接驱动装置1300。
本申请提供一种用于样本检测设备的控制设备，由主控制装置控制中控装置并由中控装置控制驱动装置，简化了主控装置的主控指令和结构，降低样本检测设备出现异常的概率，保证样本检测设备得到有 效的样本检测结果。同时，当样本检测设备发生异常时，只需要更换发生异常的装置，不需要连同主控制装置、中控装置及驱动装置一并进行更换。
本申请实施例还提供一种样本检测设备，包括本实施例中用于样本检测设备的控制设备1000。
样本检测设备还包括执行装置，执行装置的类型是根据需求设置的，可以是机械臂、枪头丢弃装置、脱柱塞装置、进料装置、送料装置、开舱装置等设备，在此不做赘述。如图所示，在驱动装置1300未连接执行装置的情况下，驱动装置1300响应指令并直接执行检测流程的动作。在驱动装置1300连接执行装置的情况下，驱动装置1300驱动执行装置执行检测流程的动作。驱动装置1300是否连接执行装置，是根据驱动装置1300的实际需求设置的，在此不做赘述。
本申请实施例还提供一种计算机设备，计算机设备包括存储器及处理器，存储器存储有计算机程序，计算机程序在处理器执行时，实现如上述的用于样本检测设备的控制方法。
本申请实施例还提供一种计算机可读存储介质，计算机可读存储介质上存储有计算机程序，计算机程序被处理器执行时，实现如上述的用于样本检测设备的控制方法。
本领域内的技术人员应明白，本申请的实施例可提供为方法、系统、或计算机程序产品。因此，本申请可采用完全硬件实施例、完全软件实施例、或结合软件和硬件方面的实施例的形式。而且，本申请可采用在一个或多个其中包含有计算机可用程序代码的计算机可用存储介质(包括但不限于磁盘存储器、CD-ROM、光学存储器等)上实施的计算机程序产品的形式。
本申请是参照根据本申请实施例的方法、设备(系统)、和计算机程序产品的流程图和/或方框图来描述的。应理解可由计算机程序指令实现流程图和/或方框图中的每一流程和/或方框、以及流程图和/或方框图中的流程和/或方框的结合。可提供这些计算机程序指令到通用计算机、专用计算机、嵌入式处理机或其他可编程数据处理设备的处理器以产生一个机器，使得通过计算机或其他可编程数据处理设备的处理器执行的指令产生用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的装置。
这些计算机程序指令也可存储在能引导计算机或其他可编程数据处理设备以特定方式工作的计算机可读存储器中，使得存储在该计算机可读存储器中的指令产生包括指令装置的制造品，该指令装置实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能。
这些计算机程序指令也可装载到计算机或其他可编程数据处理设备上，使得在计算机或其他可编程设备上执行一系列操作步骤以产生计算机实现的处理，从而在计算机或其他可编程设备上执行的指令提供用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的步骤。
在一个典型的配置中，计算设备包括一个或多个处理器(CPU)、输入/输出接口、网络接口和内存。
存储器可能包括计算机可读介质中的非永久性存储器，随机存取存储器(RAM)和/或非易失性内存等形式，如只读存储器(ROM)或闪存(flash RAM)。存储器是计算机可读介质的示例。
计算机可读存储介质包括永久性和非永久性、可移动和非可移动媒体可以由任何方法或技术来实现信息存储。信息可以是计算机可读指令、数据结构、程序的模块或其他数据。计算机的存储介质的例子包括，但不限于相变内存(PRAM)、静态随机存取存储器(SRAM)、动态随机存取存储器(DRAM)、其他类型的随机存取存储器(RAM)、只读存储器(ROM)、电可擦除可编程只读存储器(EEPROM)、快闪记忆体或其他内存技术、只读光盘只读存储器(CD-ROM)、数字多功能光盘(DVD)或其他光学存储、磁盒式磁带，磁带磁磁盘存储或其他磁性存储设备或任何其他非传输介质，可用于存储可以被计算设备访问的信息。按照本文中的界定，计算机可读介质不包括暂存电脑可读媒体(transitory media)，如调制的数据信号和载波。
还需要说明的是，术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含，从而使得包括一系列要素的过程、方法、商品或者设备不仅包括那些要素，而且还包括没有明确列出的其他要素，或者是还包括为这种过程、方法、商品或者设备所固有的要素。在没有更多限制的情况下，由语句“包括一个……”限定的要素，并不排除在包括要素的过程、方法、商品或者设备中还存在另外的相同要素。
以上仅为本申请的实施例而已，并不用于限制本申请。对于本领域技术人员来说，本申请可以有各 种更改和变化。凡在本申请的精神和原理之内所作的任何修改、等同替换、改进等，均应包含在本申请的权利要求范围之内。

Claims (15)

  1. 一种用于样本检测设备的控制方法，其特征在于，所述样本检测设备包括主控制装置、多个中控装置及多个驱动装置，所述方法包括：
    利用所述主控制装置基于样本的检测流程，生成主控指令，并将所述主控指令发送至每个所述中控装置，其中，所述主控指令用于控制目标中控装置执行所述检测流程，所述目标中控装置为可解析所述主控指令的所述中控装置；
    利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，其中，所述目标驱动装置为与所述目标中控装置连接的所述驱动装置；
    利用所述目标驱动装置响应所述组合逻辑中控指令，执行所述检测流程的动作。
  2. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述方法还包括：
    利用所述主控制装置获取所述中控装置生成的指令完成信号，并基于所述指令完成信号确定是否完成样本检测；
    在未完成样本检测的情况下，执行利用所述主控制装置基于样本的检测流程，生成主控指令，并将所述主控指令发送至每个所述中控装置的步骤。
  3. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述方法还包括：
    在所述目标驱动装置完成所述动作的情况下，利用所述目标驱动装置生成动作完成信号，并将所述动作信号发送至所述目标中控装置；
    利用所述目标中控装置根据所述动作完成信号，检测是否完成所述主控指令；
    在未完成所述主控指令的情况下，利用所述目标中控装置将所述组合逻辑中控指令发送至下一个目标驱动装置。
  4. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括开合盖中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述开合盖中控装置的情况下，利用所述开合盖中控装置解析所述主控指令，生成第一组合逻辑中控指令，并将所述第一组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第一组合逻辑中控指令用于控制所述目标驱动装置执行开盖和合盖的组合动作。
  5. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括移液中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述移液中控装置的情况下，利用所述移液中控装置解析所述主控指令，生成第二组合逻辑中控指令，并将所述第二组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第二组合逻辑中控指令用于控制所述目标驱动装置执行吸取试剂、混合试剂的组合动作。
  6. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括提取中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述提取中控装置的情况下，利用所述提取中控装置解析所述主控指令，生成第三组合逻辑中控指令，并将所述第三组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第三组合逻辑中控指令用于控制所述目标驱动装置执行提取核酸的组合动作。
  7. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括送样中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述送样中控装置的情况下，利用所述送样中控装置解析所述主控指令，生成第四组合逻辑中控指令，并将所述第四组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第四组合逻辑中控指令用于控制所述目标驱动装置执行送样的组合动作。
  8. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括功能中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述功能中控装置的情况下，利用所述功能中控装置解析所述主控指令，生成第五组合逻辑中控指令，并将所述第五组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第五组合逻辑中控指令用于控制所述目标驱动装置执行调整检测环境的组合动作。
  9. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括检测中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述检测中控装置的情况下，利用所述检测中控装置解析所述主控指令，生成第六组合逻辑中控指令，并将所述第六组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第六组合逻辑中控指令用于控制所述目标驱动装置执行获取样本检测数据的组合动作。
  10. 根据权利要求9所述的用于样本检测设备的控制方法，其特征在于，所述方法还包括：
    利用所述主控制装置获取所述检测中控装置得到的样本检测数据，并基于所述样本检测数据生成样本检测结果。
  11. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括开合盖中控装置、移液中控装置及提取中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述开合盖中控装置的情况下，利用所述开合盖中控装置解析所述主控指令，生成第一组合逻辑中控指令，并将所述第一组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第一组合逻辑中控指令用于控制所述目标驱动装置执行开盖和合盖的组合动作；
    在所述目标中控装置为所述移液中控装置的情况下，利用所述移液中控装置解析所述主控指令，生成第二组合逻辑中控指令，并将所述第二组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第二组合逻辑中控指令用于控制所述目标驱动装置执行吸取试剂、混合试剂的组合动作；
    在所述目标中控装置为所述提取中控装置的情况下，利用所述提取中控装置解析所述主控指令，生成第三组合逻辑中控指令，并将所述第三组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第三组合逻辑中控指令用于控制所述目标驱动装置执行提取核酸的组合动作。
  12. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括送样中控装置和检测中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述送样中控装置的情况下，利用所述送样中控装置解析所述主控指令，生成第四组合逻辑中控指令，并将所述第四组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第 四组合逻辑中控指令用于控制所述目标驱动装置执行送样的组合动作；
    在所述目标中控装置为所述检测中控装置的情况下，利用所述检测中控装置解析所述主控指令，生成第六组合逻辑中控指令，并将所述第六组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第六组合逻辑中控指令用于控制所述目标驱动装置执行获取样本检测数据的组合动作。
  13. 根据权利要求1所述的用于样本检测设备的控制方法，其特征在于，所述中控装置包括开合盖中控装置、移液中控装置、提取中控装置、送样中控装置及检测中控装置，所述利用所述目标中控装置解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，包括：
    在所述目标中控装置为所述开合盖中控装置的情况下，利用所述开合盖中控装置解析所述主控指令，生成第一组合逻辑中控指令，并将所述第一组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第一组合逻辑中控指令用于控制所述目标驱动装置执行开盖和合盖的组合动作；
    在所述目标中控装置为所述移液中控装置的情况下，利用所述移液中控装置解析所述主控指令，生成第二组合逻辑中控指令，并将所述第二组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第二组合逻辑中控指令用于控制所述目标驱动装置执行吸取试剂、混合试剂的组合动作；
    在所述目标中控装置为所述提取中控装置的情况下，利用所述提取中控装置解析所述主控指令，生成第三组合逻辑中控指令，并将所述第三组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第三组合逻辑中控指令用于控制所述目标驱动装置执行提取核酸的组合动作；
    在所述目标中控装置为所述送样中控装置的情况下，利用所述送样中控装置解析所述主控指令，生成第四组合逻辑中控指令，并将所述第四组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第四组合逻辑中控指令用于控制所述目标驱动装置执行送样的组合动作；
    在所述目标中控装置为所述检测中控装置的情况下，利用所述检测中控装置解析所述主控指令，生成第六组合逻辑中控指令，并将所述第六组合逻辑中控指令依次发送至每个目标驱动装置，其中，所述第六组合逻辑中控指令用于控制所述目标驱动装置执行获取样本检测数据的组合动作。
  14. 一种样本检测设备，其特征在于，所述样本检测设备包括主控制装置、多个中控装置及多个驱动装置；
    所述主控制装置，用于基于样本的检测流程，生成主控指令，并将所述主控指令发送至每个所述中控装置，其中，所述主控指令用于控制目标中控装置执行所述检测流程，所述目标中控装置为可解析所述主控指令的所述中控装置；
    所述目标中控装置，用于解析所述主控指令，生成组合逻辑中控指令，并将所述组合逻辑中控指令发送至目标驱动装置，其中，所述目标驱动装置为与所述目标中控装置连接的所述驱动装置；
    所述目标驱动装置，用于响应所述组合逻辑中控指令，执行所述检测流程的动作。
  15. 一种计算机可读存储介质，其特征在于，所述计算机可读存储介质上存储有计算机程序，所述计算机程序被处理器执行时，实现如权利要求1至11、权利要求11及权利要求12中任一项所述的用于样本检测设备的控制方法。
PCT/CN2024/093875 2023-05-22 2024-05-17 用于样本检测设备的控制方法、样本检测设备及存储介质 Ceased WO2024240071A1 (zh)

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