WO2025072977A1 - Robot télescopique - Google Patents

Robot télescopique Download PDF

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Publication number
WO2025072977A1
WO2025072977A1 PCT/US2024/049346 US2024049346W WO2025072977A1 WO 2025072977 A1 WO2025072977 A1 WO 2025072977A1 US 2024049346 W US2024049346 W US 2024049346W WO 2025072977 A1 WO2025072977 A1 WO 2025072977A1
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WO
WIPO (PCT)
Prior art keywords
link
links
mount
assembly
overtube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2024/049346
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English (en)
Inventor
Roman Devengenzo
Spencer J. WITTE
Neal Tanner
Aren HILL
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Neptune Medical Inc
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Neptune Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neptune Medical Inc filed Critical Neptune Medical Inc
Priority to AU2024353942A priority Critical patent/AU2024353942A1/en
Publication of WO2025072977A1 publication Critical patent/WO2025072977A1/fr
Anticipated expiration legal-status Critical
Pending legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
    • B25J18/00—Arms
    • B25J18/02—Arms extensible
    • B25J18/025—Arms extensible telescopic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00147—Holding or positioning arrangements
    • A61B1/00149—Holding or positioning arrangements using articulated arms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00147—Holding or positioning arrangements
    • A61B1/00154—Holding or positioning arrangements using guiding arrangements for insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00147—Holding or positioning arrangements
    • A61B1/0016—Holding or positioning arrangements using motor drive units

Definitions

  • Medical procedures such as endoscopy may involve accessing and visualizing the inside of a patient's anatomy for diagnostic and/or therapeutic purposes.
  • gastroenterology, urology, and bronchoscopy involve medical procedures that allow a physician to examine patient lumens, such as the gastrointestinal tract, urology tract, vasculature, and airways.
  • flexible tools or instruments generally referred to as flexible tubular members such as endoscopes, overtubes, catheters, or guidewires, are inserted into the patient through an orifice (e.g., a natural orifice or an incision) and advanced towards a tissue site identified for subsequent diagnosis and/or treatment.
  • the medical instrument can be controllable and articulable to facilitate navigation through the anatomy.
  • Colonoscopes are just one example of a device, in this case an endoscope, that may be long and difficult to manage, particularly for robotic systems in which advancing/retracting and/or steering may be driven by a controller such as a robotic controller
  • Enteroscopes are used for navigation of the small intestine, and they may be even longer in length. Similar challenges exist for catheters, which are also longer length and flexible.
  • Vascular catheters may advance into the neurovasculature, peripheral vasculature, pulmonary vasculature, and the cardiac and coronary vasculature.
  • Guidewires may be used in the vasculature, usually in conjunction with catheters.
  • Overtubes may be used with endoscopes. Overtubes may be used in conjunction with endoscopes, or an endoscope may be withdrawn such that only an overtube remains.
  • Described herein are robotic apparatuses (e.g., systems, devices, etc.) and methods for positioning (relative to the patient), loading, dispensing or deploying, driving (e.g., advancing/retracting, steering, etc.), and withdrawing one or more flexible tubular members.
  • a flexible tubular member may include one or more of: endoscopes, catheters, overtubes and/or guidewires, and in particular long-length endoscopes, including colonoscopes and enteroscopes.
  • the methods and apparatuses described herein may address the challenges of positioning, loading, dispensing or deploying, driving, and withdrawing and/or otherwise operating such elongate medical instruments.
  • these apparatuses provide a telescoping platform for supporting and controlling a flexible tubular member, and in particular a nested robotic endoscope that may provide significant advantages over previously described delivery and control platforms.
  • the telescoping platform may allow extension and retraction relative to a base in both proximal and distal directions (e.g., bidirectional) from an un-extended neutral position in which the platform (e.g., the link assembly) has a compact footprint.
  • This design may generally be significantly more compact than previously described positioning and/or controlling systems, and in particular than previously described telescoping positioning and/or controlling systems.
  • each link may be a platform or plank shape that is generally long and thin.
  • Each link may have a width that is less than the length and height, and may include a first major surface along both a front side and a back side (along the length and height).
  • the link may enclose one or more elements within its thickness, such as a belt (e.g., a synchronization belt, as described below).
  • the links of the link assembly may be similar or identical in their general shape.
  • the innermost link may be coupled to the mount assembly or attachments for the flexible tubular member and/or flexible tubular member driver).
  • the mount assembly may be configured to include multiple actuating regions that may separately mount to different regions of the flexible tubular member, or in some cases an inner endoscope and an outer overtube, which may move relative to each other.
  • the outmost link may be coupled to the link assembly driver and/or may couple to the rest of the system, e.g., to the base or to an arm supported by the base.
  • the links may have a rectangular cross-section (or generally rectangular, e.g., rectanguloid) that has a thickness that is less than its height (vertical height) and that is longer (in a proximal-to-distal direction) than it is wide or high.
  • arranging the link assembly with the links in a vertical direction may both provide superior support as the links are coupled adjacent to each other along their width (e.g., sistered to each other jvertically, as well as permitting the mounting region for the flexible tubular member (in some cases both the inner and outer members of a nested device, e.g., mounting to different portions of a mounting assembly) to be positioned lower than (e.g., closer to the floor) the top of the vertically-arranged link assembly. Since in some embodiments the spacing between the surface of the bed or table on which the patient is positioned and the entry point into the patient’s anatomy (e.g., anus, mouth, etc.) may be limited, this configuration may permit access that is in-line with the patient’s body.
  • a link may refer to a body such as a plate, panel, frame, leaf, slab, etc.
  • the link may be solid or hollow, and/or may include one or more internal structures.
  • the link may include one or more windows, opening, or passages therethrough.
  • the flexible tubular member described herein may be an elongate medical instrument and may be referred to as robotic elongate medical instruments, robotic endoscopes or robotic scopes.
  • These elongate medical instruments may include endoscopes, which may be actuated as described herein by the drive system, including robotic drive systems.
  • Endoscopes may include colonoscopes, bronchoscope, colposcope, cystoscope, esophagoscope, gastroscope, laparoscope, thoracoscope, enteroscope, etc.
  • the methods and apparatuses described herein may be particularly desirable for use with longer elongate medical instruments (e.g., having a length of greater than 0.7 m, 0.8 m, 0.9 m, 1 m, 1.2 m, 1.4 m, 1.6 m, 2.0 m, 2.1 m, 3 m, etc ).
  • These apparatuses may work well with flexible tubular members. These apparatuses may work particularly well with elongate medical instruments that include nested (i.e., two or more) components that may extend and retract relative to each other, such as telescoping elongate medical instruments.
  • a telescoping elongate medical instrument may include an inner robotic scope and an outer overtube.
  • a telescoping elongate medical instrument may include an inner robotic scope and an outer robotic scope. Either or both the inner and outer robotic scopes may be steerable, e.g., may include one or more steering member (e.g., steering tendons, etc.) that may mate with a steering interface on the apparatus.
  • Either or both of the inner and outer scopes may include vision systems.
  • the drive system may include a steering interface for the robotic scope, and in some examples for either or both an inner and an outer member of the robotic scope.
  • DOF Degrees of Freedom
  • the methods and apparatuses described herein may be particularly well suited for controlling rigidizing elongate medical instruments (i.e., Dynamic RigidizationTM).
  • Rigidizing elongate medical instruments may include, but are not limited to, elongate medical instruments that are rigidized by multiple methods.
  • One method for rigidization is the application of pressure (e.g., positive pressure and/or negative pressure).
  • the apparatuses and methods described herein may be particularly well suited for telescoping rigidizing elongate medical instruments in which an outer member of the robotic scope is a rigidizable member that may be rigidized by the application of pressure, and an inner member is a rigidizable member that may be rigidized by the application of pressure.
  • the inner and outer members may be controllably rigidized separately and/or independently (or in a coordinated manner) which may be integrated with the drive system (e.g., robotic drive system).
  • any of these apparatuses may be configured with components that are single use (‘disposable’), multiple or multi-use (‘resposable’), sheathed, or a very large number of uses (‘reusable’). These elements may be engineered to reduce cost and landfill. They may be engineered for lower effective per-case cost. They may be engineered for ease of use, ease of install, fast procedure set-up, and ease of removal. Any of these apparatuses may be configured to allow reuse of drive system and frame, and other components that are coupled to the drive system, and may include one or more disposable components such as trays, cartridges, or the like to allow use with multiple robotic scopes, which may include sterile versions or sterile boundaries or layers.
  • the apparatus may be configured so that the reusable component (e.g., the vertically-arranged link assembly, mount assembly, etc.) may be configured to be kept separate from the sterile field, e.g., by the use of a drape or cover.
  • the reusable component e.g., the vertically-arranged link assembly, mount assembly, etc.
  • drapes may engage with the apparatuses coupled to or including the drive systems described herein.
  • apparatuses for deploying a flexible tubular member that includes: a base; a vertically-arranged link assembly connected to the base and include a plurality of links that are vertically adjacent to each other, wherein adjacent pairs of links are each slidably coupled together by one or more mechanical movement coupling, e.g., flexible bands that extend at least partially around a cylindrical surface of a shuttle, wherein pairs of shuttles between adjacent links of adjacent pairs of links are coupled together on a synchronization belt; a driver (e.g., a linear driver) coupled to a first shuttle of the pairs of shuttles; and a first portion of a mount assembly that may be coupled to the vertically-arranged link assembly, wherein the first portion of the mount assembly is configured to couple to the flexible tubular member.
  • a driver e.g., a linear driver
  • a driver e.g., a linear driver
  • the apparatus may include a synchronization belt that may be configured to move the first shuttle in an opposite direction relative to the second shuttle.
  • the synchronization belt may be within the link that is between the two shuttles to which it is connected.
  • the synchronization band may be coupled to a pair of pulleys so that movement of the first shuttle in the distal direction moves the second shuttle in the proximal direction and vice versa.
  • the bands that extend between the links are coupled to the opposite sides of the links (e.g., to the sides of the links that face each other) at the same ends, e.g., the distal ends or the proximal ends.
  • a pair of bands arranged in an opposing configuration, may connect the ends of facing links of the link assembly after passing around the cylindrical surface (e.g., pulley) at different region of the cylindrical surface.
  • the first end of a first band of the opposing bands may be coupled to a distal end region of a first link of the adjacent pairs of links and to a distal end region of a second link of the adjacent pairs of links.
  • the first end of a second band of the opposing bands may be coupled to a proximal end region of the first link of the adjacent pairs of links and to a proximal end region of the second link of the adjacent pairs of links.
  • the flexible bands and/or belts may be formed of a flat, relatively thin and flexible material, including a thin flat metal (e.g., stainless steel, etc.).
  • the flexible bands may comprise flat bands.
  • the width of the flat band may be many times the thickness (e.g., greater than 5x, lOx, 15x, 20x, etc.).
  • the flat band may have a width of 0.5 cm, 1 cm, 1.5 cm, 2 cm, 3 cm, 4 cm, 5 cm, etc.
  • the plurality of links may each have a vertical height that is greater than a width and less than a distal to proximal length. In some examples, the plurality of links may each have a vertical height that is less than a distal to proximal length, and at least twice a width.
  • the links may be between about 10 cm and 100 cm (e.g., between 15 cm and 75 cm, between 20 cm and 60 cm, etc.) long, between about 3 cm and 30 cm high (e.g., between 4 cm and 20 cm, between 5 cm and 18 cm, etc.), and between about 0.5 cm and 6 cm wide (e.g., between about 1 cm and 5 cm, between about 0.5 cm and 4 cm, etc.).
  • the mount assembly for coupling to the flexible tubular member may be coupled to one of the outer links of the link assembly, such as to an outer link of the plurality of links of the vertically- arranged link assembly.
  • the mount assembly may include one or more drivers for steering and/or otherwise manipulating the flexible tubular member.
  • the flexible tubular member is a nested device (e.g., a nested, rigidizing robotic device) having an inner endoscope and an outer overtube
  • the mount assembly may include a first region (or portion) configured to mount to the outer overtube and a second region (or portion) configured to mount to the inner endoscope.
  • the mount assembly may be configured so that these two regions may move relative to each other to allow relative movement of the inner vs. outer members of the nested device.
  • the first mount region may be configured to couple to a nested robotic device having an overtube within which the endoscope is nested within.
  • the mount assembly may include an overtube mount (first mount region) and an endoscope mount (second mount region), wherein the endoscope mount is configured to move proximally and/or distally relative to the overtube mount.
  • any of these apparatuses may be configured to allow position of the link assembly (and therefore the endoscope) in multiple degrees of freedom.
  • these apparatuses may be configured to allow the device to adjust the height of the link assembly relative to the base (e.g., the floor).
  • Any of these apparatuses may include a vertical lift arm coupling the vertically-arranged link assembly to the base, wherein the vertical lift arm is configured to raise and lower the vertically-arranged link assembly relative to the base.
  • the apparatus may include a yaw adjust member between the vertically-arranged link assembly and the base, wherein the yaw adjust member is configured to swing the vertically- arranged link assembly pivotally around the base.
  • the apparatus may include one or more locks for locking these devices in a particular configuration.
  • the link assembly may be coupled to the base either directly or through one or more arms.
  • Any appropriate drive may be used to drive movement of the shuttle and therefore extension and/or retraction of the link assembly.
  • the drive may be a linear drive (e.g., that converts rotary motion into linear (distal/proximal) movement.
  • the drive may include a ball screw nut assembly.
  • the liner drive is housed within the first link of the plurality of links (e.g., the link coupled to the base either directly or indirectly).
  • the drive (e.g., linear drive) for the link assembly may be separate from the link assembly and may be eternal to the links, but may couple to the shuttle (the first shuttle, which may also be referred to as the drive shuttle) through the first link.
  • any of the apparatuses described herein may include a controller including one or more processors, and control circuitry for receiving control input, providing output to control and/or coordinate extension/retraction of the link assembly and/or the flexible tubular member driver (e.g., overtube driver and/or endoscope driver in nested configurations).
  • a controller may be configured to control the linear drive to move links (e.g., plates) of the plurality of links distally and proximally relative to the base controlling operation of the linear driver.
  • the controller may include control logic (software, firmware, and/or hardware) for performing any of the methods described herein.
  • the controller may coordinate with the steering and/or, in examples using a rigidizing device, rigidizing of the catheter.
  • the controller may receive user input and may automate some or all of the guidance of the apparatus.
  • the controller may receive and process (or transmit and/or store) inputs from one or more sensors.
  • any of the apparatuses described herein may include a flexible tubular member support coupled to the vertically-arranged link assembly and configured to prevent buckling of the flexible tubular member at it extends distally from the vertically-arranged link assembly.
  • the flexible tubular member support (referred to here as an endoscope support or simply a support) may be a strut, beam, rod, pole, etc. that may support the length of the flexible tubular member as it extends distally and/or proximally away from the link assembly.
  • the flexible tubular member support may include one or more loops or straps for holding (and supporting) a portion of the flexible tubular member.
  • any of the apparatuses described herein may include a tool driver for operating or assisting in operating a tool that is inserted into or through a working channel (internal or external working channel) of the flexible tubular member.
  • a tool driver may be coupled to the vertically-arranged link assembly and configured to actuate a tool within a working channel of an endoscope comprising the flexible tubular member.
  • any of these apparatuses may include one or more sensors configured to detect one or more operating parameters for the system.
  • the apparatus may include one or more load sensors configured to detect a load applied to the vertically-arranged link assembly.
  • the one or more load sensors may be configured as a current sensor that detects current of, e.g., the linear driver.
  • Any of the apparatuses described herein may be configured to work with a variety of elongate medical instruments (robotic scopes). However, in any of these apparatuses, the elongate medical instruments (e.g., robotic scope) may be included as part of the system.
  • any of these apparatuses may include the elongate medical instrument (e.g., the robotic scope).
  • the system may include the robotic scope, which may be a colonoscope.
  • the robotic scope included with the apparatus is a rigidizable flexible tubular member comprising a rigidizable inner member concentrically positioned within a rigidizable outer member.
  • any of these apparatuses may include a pressure input configured to couple the robotic scope to a pressure source to control rigidity of the robotic scope, including either or both an inner member and outer member in variations including inner and outer members.
  • systems for deploying a flexible tubular member comprising: a base; a telescoping link assembly connected to the base and comprising: a plurality of links that are adjacent to each other, wherein adjacent pairs of links are each slidably coupled together, wherein the plurality of links are configured to extend from a compact configuration to a length of 0.6 m or longer; a linear driver configured to drive movement of the links of the telescoping link assembly; and a mount assembly coupled to the link assembly, wherein the mount assembly is configured to couple to the flexible tubular member.
  • the compact configuration may have a significantly smaller length (e.g., extending in a distal to proximal direction) than the extended length of the device.
  • the length of the compact configuration may be 50% or less than the length of the fully extended configuration (e.g., 45% or less, 40% or less, 35% or less, 30% or less, 25% or less, 20% or less, etc.).
  • any of these apparatuses may be bidirectional, so that they may expand distally or proximally from the compact configuration.
  • the telescoping link assembly may be bidirectional, and the compact configuration may be a neutral configuration such that the plurality of links may be extended either distally from the neutral configuration to a length of 0.6 m or longer or proximally from the neutral configuration to a length of 0.6 m or longer.
  • Bidirectional expansion provides many advantages, particularly as compared to systems that expand only in one direction, e.g., from a stable or fixed base. Bidirectional systems may allow a much more compact foot print in the compact configuration, and may allow use of the apparatus in even very narrow or space-constrained regions, including next to a hospital bed or operating table.
  • Bidirectional apparatuses may provide a longer travel distance when moving in the distal to proximal axis.
  • Any of the apparatuses described herein may include a plurality of links that are vertically adjacent to each other, relative to ground. Thus, the links may be arranged side-by- side, rather than on top of each other.
  • any of these apparatuses may be configured so that moving any of the individual links causes a coordinated movement of all or some of the other links; for example, driving movement (proximal/distal movement) of the first link may extend the set of links in the same direction of movement.
  • This may advantageously allow control of movement by a single driver (or set of drivers operating on a single link, e.g., coupled to the base).
  • this may be achieved using one or more synchronizing members coupled to each link of the plurality of links configured to coordinate movement of all of the links when force is applied to one of the links.
  • the synchronization member may be mechanical (e.g., belts, bands, etc.) and/or may include software or firmware to coordinate between the different links.
  • each link may be individually driven, and the activity of the drives may be coordinated by one or more processors.
  • a mount assembly may include an overtube mount and an endoscope mount, wherein the endoscope mount is configured to move proximally and/or distally relative to the overtube mount.
  • the link assembly may be configured to extend from the compact configuration to any appropriate length.
  • the link assembly may be configured to extend to a length of 1 m or longer (e g., 1.1 m or longer, 1.2 m or longer, 1.3 m or longer, 1.4 m or longer, 1.5 m or longer 1.6 m or longer, 1.7 m or longer, 1.8 m or longer, 1.9 m or longer, 2 m or longer, etc.).
  • the apparatuses described herein may have a very small distal clearance height or offset.
  • the height of the mount assembly relative to the link assembly may be adjustable and/or may be relatively low.
  • a vertical distance from the mount assembly to lowermost surface of the link assembly may be less than 20 cm (e.g., 20 cm or less, 19 cm or less, 18 cm or less, 17 cm or less, 16 cm or less, 15 cm or less, 14 cm or less, 12 cm or less, 10 cm or less, etc.).
  • the distal end of the mount assembly and link assembly may extend distally to a patient positioned on a bed or table and may be positioned in-line with a patient orifice even when the orifice is relatively close to the bed/table surface (e.g., less than 20 cm) without interference between the bed/table and the distal end of the extended apparatus.
  • the links may be configured to smoothly slide relative to each other to extend/retract distally and/or proximally.
  • the plurality of links may be configured so that adjacent pairs of links are each slidably coupled together by a pair of opposing flexible bands that extend around one or more surfaces of shuttle in opposite directions.
  • the link assembly may comprise one or more (e.g., a pair) of shuttles between adjacent links of adjacent pairs of links; the shuttles may be coupled together on a synchronization member (e.g., synchronization belt).
  • Also described herein are systems for deploying a flexible tubular member comprising: a base; a bidirectional telescoping link assembly connected to the base and comprising: a plurality of links that are adjacent to each other, wherein adjacent pairs of links are each slidably coupled together, wherein the plurality of links are configured to extend proximally from a compact neutral configuration to a proximal extended configuration and to extend distally from the compact neutral configuration to a distal extended configuration, wherein the compact neutral configuration has a length that is 50% or less than a length of the proximal extended configuration and 50% or less a length of the distal extended configuration; a linear driver configured to drive movement of the links of the telescoping link assembly; and a mount assembly coupled to the link assembly, wherein the mount assembly is configured to couple to the flexible tubular member.
  • the plurality of links may be vertically adjacent to each other.
  • the plurality of links may be horizontally adjacent to each other (e.g., stacked).
  • any of these apparatuses may include one or more synchronizing members coupled to each link of the plurality of links configured to coordinate movement of all of the links when force is applied to one of the links.
  • the mount assembly may comprise an overtube mount and an endoscope mount, wherein the endoscope mount is configured to move proximally and/or distally relative to the overtube mount.
  • the link assembly may be configured to extend from the compact configuration to a length of 1 m or longer.
  • the vertical distance from the mount assembly to lowermost surface of the link assembly may be less than 20 cm.
  • the plurality of links may be configured so that adjacent pairs of links are each slidably coupled together by a ball screw nut assembly.
  • the plurality of links may be configured so that adjacent pairs of links are each slidably coupled together by a pair of opposing flexible bands that extend around one or more surfaces of shuttle in opposite directions. Any of these apparatuses may include one or more (e.g., a pairs) of shuttles between adjacent links of adjacent pairs of links that are coupled together on a synchronization belt.
  • Also described herein are systems for deploying a flexible tubular member comprising: a base; a vertically-arranged link assembly connected to the base and comprising: a plurality of links that are vertically adjacent to each other, wherein adjacent pairs of links are each slidably coupled together by a pair of opposing flexible bands that extend around one or more surfaces of a shuttle in opposite directions, wherein pairs of shuttles between adjacent links of adjacent pairs of links are coupled together on a synchronization belt; a linear driver coupled to a first shuttle of the pairs of shuttles; and a mount assembly coupled to the vertically-arranged link assembly, wherein the mount assembly is configured to couple to the flexible tubular member.
  • the synchronization belt may be configured to move the first shuttle in an opposite direction relative to the second shuttle.
  • a first end of a first band of the opposing bands may be coupled to a distal end region of a first link of the adjacent pairs of links and to a distal end region of a second link of the adjacent pairs of links, wherein a first end of a second band of the opposing bands may be coupled to a proximal end region of the first link of the adjacent pairs of links and to a proximal end region of the second link of the adjacent pairs of links.
  • the flexible bands may comprise flat bands.
  • the flexible bands may comprise metallic bands.
  • the plurality of links may each have a vertical height that is greater than a width and less than a distal to proximal length.
  • the plurality of links may each have a vertical height that is less than a distal to proximal length, and at least twice a width.
  • the cylindrical surfaces may comprise pulleys.
  • the mount assembly may be coupled to an outer link of the plurality of links of the vertically-arranged link assembly.
  • any of these apparatuses may include a vertical lift arm having a vertical axis coupling the vertically-arranged link assembly to the base, wherein the vertical lift arm is configured to raise and lower the vertically-arranged link assembly relative to the base.
  • Any of these apparatuses may include a yaw adjust member between the vertically-arranged link assembly and the base, wherein the yaw adjust member is configured to swing the vertically-arranged link assembly pivotally around the base.
  • the mount assembly may be configured to couple to the flexible tubular member that comprises a nested robotic device having an overtube within which an inner endoscope is nested.
  • the mount assembly may comprise an overtube mount and an endoscope mount, wherein the endoscope mount is configured to move proximally and/or distally relative to the overtube mount.
  • the liner drive may comprise a ball screw nut assembly, or any other appropriate linear driver.
  • the liner drive may be housed within a first link of the plurality of links.
  • the linear driver may be housed external to the first link.
  • Any of these apparatuses may include a controller configured to control the linear drive to move links of the plurality of links distally and proximally relative to the base controlling operation of the linear driver.
  • Any of these apparatuses may include a flexible tubular member support coupled to the vertically-arranged link assembly and configured to prevent buckling of the flexible tubular member at it extends distally from the vertically-arranged link assembly.
  • the mount assembly may be below the top of the vertically- arranged link assembly.
  • the apparatuses described herein may include a tool driver coupled to the vertically-arranged link assembly and configured to actuate a tool within a working channel of the flexible tubular member.
  • any of these apparatuses may include one or more sensors configured to detect one or more operating parameters for the system.
  • these apparatuses may include one or more load sensors configured to detect a load applied between the vertically-arranged link assembly and the patient. The load may be transmitted through the one or more flexible tubular member (e.g., endoscope, etc.).
  • the one or more load sensors may comprise a current sensor configured to detect current of the linear driver.
  • the mount assembly (e.g., in some example coupled to a vertically-arranged link assembly) may be coupled to the base either directly or through one or more arms.
  • a system for deploying a flexible tubular member comprising: a base; a vertically-arranged link assembly connected to the base and comprising: a first link, a second link and a third link, wherein the first, second and third links are vertically adjacent to each other; a first shuttle between the first and second link and a second shuttle between the second and third link, wherein the first is movably coupled between the first and second links and the second shuttle is movably coupled between the second and third links so that the second and third links may slide distally and proximally relative to the first link, and wherein the first shuttle comprises a first vertical cylindrical surface and the second shuttle comprises a second vertical cylindrical surface; a linear driver coupled to the first shuttle; a first flexible band between the first and second links, the first flexible band extending from a first end region of the first link, around the first vertical cylindrical surface, and extending to a first end region of the second link; a second flexible band between the second and third links, the second flexible band extending
  • the apparatus may include a third flexible band between the first and second links, the third flexible band extending from a second end region of the first link, around the first vertical cylindrical surface, and extending to a second end region of the second link, and a fourth flexible band between the second and third links, the fourth flexible band extending from the second end region of the second link, around the second vertical cylindrical surface and extending to the second end region of the third link.
  • Any of these apparatuses may include a synchronization belt coupled to the first shuttle and to the second shuttle, and configured to move the first shuttle relative to the second shuttle.
  • the motion of the linear drive may be transmitted to the third link with a 4: 1 ratio or greater.
  • any of the apparatuses described herein may include the link assembly and the mount assembly for use with a telescoping (e.g., nested) elongate member.
  • a telescoping e.g., nested
  • systems for deploying a nested robotic device having an inner rigidizing member slidably disposed at least partially within an outer rigidizing member comprising: a base; a vertically-arranged link assembly connected to the base and comprising: a first link, a second link and a third link, wherein the first, second and third links are vertically adjacent to each other; a first shuttle between the first and second link and a second shuttle between the second and third link, wherein the first is movably coupled between the first and second links and the second shuttle is movably coupled between the second and third links so that the second and third links may slide distally and proximally relative to the first link, and wherein the first shuttle comprises a first vertical cylindrical surface and the second shuttle comprises a second vertical cylindrical surface; a linear driver coupled
  • a method of deploying an endoscope nested with an overtube may include: advancing and/or retracting the overtube together with the endoscope by moving a first link of a bidirectional telescoping link assembly, wherein the overtube is coupled to an overtube mount on the first link and wherein the endoscope is coupled to an endoscope mount on the first link, and wherein the bidirectional link assembly comprises a plurality of links, including the first link, that are slidably coupled together and are adjacent to each other, and wherein advancing the overtube comprises extending the plurality of links distally from a compact neutral configuration to a proximal extended configuration and wherein retracting the overtube comprises retracting the plurality of links proximally from the compact neutral configuration to a proximal extended configuration, wherein the compact neutral configuration has a length that is 50% or less than a length of the proximal extended configuration and 50% or less a length of the
  • Any of these methods may include extending the plurality of links using a linear driver configured to drive movement of the links of the telescoping link assembly. Any of these methods may include coupling the overtube to the overtube mount, and/or coupling the endoscope nested within the overtube to the endoscope mount.
  • a method of deploying an endoscope nested with an overtube may include: advancing and/or retracting the overtube together with the endoscope by moving a first link of a bidirectional telescoping link assembly, wherein the overtube is coupled to an overtube mount on the first link and wherein the endoscope is coupled to an endoscope mount on the first link, and wherein the bidirectional link assembly comprises a plurality of links, including the first link, that are slidably coupled together and are adjacent to each other, and wherein advancing the overtube comprises extending the plurality of links distally from a compact neutral configuration to a proximal extended configuration and wherein retracting the overtube comprises retracting the plurality of links proximally from the compact neutral configuration to a proximal extended configuration, wherein the compact neutral configuration has a length that is 50% or less than a length of the proximal extended configuration and 50% or less a length of the distal extended configuration; and moving the endoscope distally into or out
  • Extending the plurality of links may include using a linear driver to drive movement of the links of the telescoping link assembly.
  • any of these methods may include coupling the overtube to the overtube mount and/or coupling the endoscope nested within the overtube to the endoscope mount.
  • apparatuses including one or more supports that are configured to support the nested, telescoping apparatus (e.g., overtube and endoscope) during operation of the apparatus, and methods of using them.
  • an apparatus may include: a telescoping link assembly comprising: a plurality of vertical links that are adjacent to each other, wherein adjacent pairs of vertical links are each slidably coupled together and configured to move relative to each other and relative to a base link; a first mount coupled to a first link of the link assembly, wherein the first mount is configured to engage an overtube; a second mount coupled to the first link and configured engage an endoscope nested with the overtube, wherein the overtube and endoscope are configured to be moved in a distal-to- proximal line by sliding the vertical links of the telescoping link assembly relative to the base link; and a plurality of supports movably coupled to the telescoping link assembly, wherein each support of the plurality of supports comprises a seating region configured to hold the overtube and endoscope in-line with the distal-to-proximal line.
  • Each support of the plurality of supports may be configured to be deflected so that the seating region of each support is moved out of the distal-to-proximal line as the plurality of the links of the telescoping link assembly are extended distally. At least some of the supports of the plurality of supports may be configured to be deflected down and laterally as the plurality of the links of the telescoping link assembly are extended distally.
  • any of these apparatuses may include a base.
  • Any of these apparatuses may include a linear driver configured to drive movement of the vertical links of the telescoping link assembly.
  • At least one of the supports of the plurality of supports may be configured to move from a deployed configuration in which the seating regions of the supports are configured to hold the overtube and endoscope in-line with the distal-to- proximal line, to a pre-deployed configuration in which the supports are raised vertically out of a plane of the distal-to-proximal line.
  • At least one of the supports of the plurality of supports may be coupled to an extender on the link assembly that is configured to extend distally from the link assembly.
  • the first and/or second mount may be configured to move relative to each other on the first link to adjust the relative positions of the endoscope and the overtube.
  • an apparatus may include: a base; a bidirectional telescoping link assembly connected to the base and comprising: a plurality of vertical links that are adjacent to each other, wherein adjacent pairs of vertical links are each slidably coupled together and configured to move bidirectionally relative to a base link; a linear driver configured to drive movement of the vertical links of the bidirectional telescoping link assembly; a first mount coupled to a first link of the link assembly, wherein the first mount is configured to engage an overtube; a second mount coupled to the first link and configured engage an endoscope nested with the overtube, wherein the overtube and endoscope are configured to be moved in a distal-to-proximal line by sliding the vertical links of the bidirectional telescoping link assembly; and a plurality of supports coupled to the telescoping link assembly, wherein each support of the plurality of supports comprises a seating region configured to move between a first configuration which the seating region holds the overtube and endoscope in-line with the distal-to
  • FIGS. 1A-1D illustrate one example of an elongate medical instrument, such as a nested robotic scope device, that may be used with the methods and apparatuses described herein.
  • the elongate medical instrument in this example is an endoscope (e.g., in some examples, a colonoscope) having a nested inner member and an outer member that are both selectively rigidizing.
  • FIG. 2 shows an example of a mechanism for actuating an elongate medical instrument similar to that shown in FIGS. 1A-1D.
  • FIG. 3A shows an example of a system for dispensing (e.g., deploying) and controlling a nested robotic device in a first configuration.
  • FIG. 3B shows the system for deploying and controlling a nested robotic device of FIG. 3A in a second configuration.
  • FIGS. 3C-3D show an example of a system similar to that shown in FIGS. 3A-3B including a flexible tubular member (e.g., a rigidizing nested overtube and inner endoscope).
  • FIG. 4 shows an example of a system for deploying and controlling a nested robotic device, illustrating eight degrees of freedom.
  • FIG. 5A shows an example of a set of vertically arranged linear links for use with a system for deploying a nested robotic device, including a first (e.g., overtube) linear driver and a second (e.g., endoscope) linear driver on an inner linear link.
  • FIG. 5B shows the vertically arranged linear links of FIG. 5 A with the second linear driver in a proximal position on the inner link.
  • FIG. 6A shows an example of a set of vertically arranged assembly of linear links for use with a system for deploying and controlling a nested robotic device in a telescoping configuration.
  • FIGS. 6B-6D illustrate views of an example of a portion of an assembly of linear links for controlling a flexible tubular member.
  • FIG. 6B shows a top front perspective view
  • FIG. 6C is a bottom front perspective view
  • FIG. 6D is a bottom perspective view.
  • FIG. 7A schematically illustrates an example of a vertically-arranged assembly of linear links for use with a system for deploying a nested robotic device.
  • FIG. 7B schematically illustrates an example of a vertically-arranged assembly of linear links for use with a system for deploying and controlling a nested robotic device similar to that shown in FIG. 7A, further including a synchronization band to synchronize movement of the links coordinating movement of the shuttles between the links.
  • FIGS. 7C-7E schematically illustrate the bidirectional operation of a vertically- arranged assembly of linear links, showing an un-extended configuration (FIG. 7C) in which the inner and intermediate links are aligned with the outer link, a proximally extended configuration (FIG. 7D) in which the inner and intermediate links telescope proximally relative to the outer link, and a distally extended configuration (FIG. 7E) in which the inner and intermediate links telescope distally relative to the outer link.
  • FIGS. 7C-7E schematically illustrate the bidirectional operation of a vertically- arranged assembly of linear links, showing an un-extended configuration (FIG. 7C) in which the inner and intermediate links are aligned with the outer link, a proximally extended configuration (FIG. 7D) in which the inner and intermediate links telescope proximally relative to the outer link, and a distally extended configuration (FIG. 7E) in which the inner and intermediate links telescope distally relative to the outer link.
  • FIGS. 7F-7H schematically illustrate the bidirectional operation of an assembly of linear links, showing an un-extended configuration (FIG. 7F) in which the inner and intermediate links are aligned with the outer link, a proximally extended configuration (FIG. 7G) in which the inner and intermediate links telescope proximally relative to the outer link, and a distally extended configuration (FIG. 7H) in which the inner and intermediate links telescope distally relative to the outer link.
  • FIGS. 7F-7H schematically illustrate the bidirectional operation of an assembly of linear links, showing an un-extended configuration (FIG. 7F) in which the inner and intermediate links are aligned with the outer link, a proximally extended configuration (FIG. 7G) in which the inner and intermediate links telescope proximally relative to the outer link, and a distally extended configuration (FIG. 7H) in which the inner and intermediate links telescope distally relative to the outer link.
  • FIGS. 7I-7K schematically illustrate the bidirectional operation of an assembly of linear links, showing an un-extended configuration (FIG. 71) in which the inner and the three intermediate links are aligned with the outer link, a proximally extended configuration (FIG. 7J), and a distally extended configuration (FIG. 7K).
  • FIG. 7L shows another example of a top view of an assembly of linear links of a robotic apparatus, showing maximum telescoping length in both a proximal and distal direction.
  • FIG. 8 illustrates one examples of an arrangement between a patient, patient bed (e.g., table, cart, etc ), a nested robotic device, and a system for deploying a nested robotic device as described herein.
  • FIG. 9 schematically illustrates an example of a system for deploying a nested robotic device in which the linear link assembly is horizontally (rather than vertically) arranged.
  • FIGS. 10A-10C illustrate examples of the relative distances and axes for accessing a patient using a system for deploying a nested robotic device.
  • FIG. 11 schematically illustrates an example of a draping system for protecting a system for deploying a nested robotic device during use.
  • FIG. 12 schematically illustrates an example of a support (e.g., support arm(s)) for use with a system for deploying a nested robotic device.
  • a support e.g., support arm(s)
  • FIG. 13 illustrates vertical and yaw adjustment of a system for deploying a nested robotic device similar to that shown in FIGS. 3A-3B and 4.
  • FIG. 14 shows an example of a tool manipulator (e.g., insertion tool) that may be used with any of the systems described herein.
  • a tool manipulator e.g., insertion tool
  • FIGS. 15A-15C show an example of a system as described herein to perform a lower-GI procedure.
  • FIGS. 16A and 16B schematically illustrate an example of a robotically-enabled system as described herein.
  • FIG. 16A shows a side perspective view and
  • FIG. 16B shows a top view.
  • FIGS. 17A-17H illustrate the operation of a flexible tubular member support when extending and retracting a set of linear links of a system as described herein.
  • FIGS. 18A and 18B schematically illustrate an example of a link assembly including a plurality of supports configured to support a nested telescoping assembly (e.g., a rigi dizing overtube/endoscope).
  • FIG. 18A shows the supports fully deployed and configured to support a nested telescoping assembly in an insertion axis.
  • FIG. 18B shows a top view of a link assembly such as the one shown in FIG. 18A with the supports fully deployed and supporting a portion of a nested telescoping assembly in the insertion axis.
  • FIGS. 19A-19H illustrate one example of the preparation of an apparatus including a link assembly and supports (e.g., flexible tubular member supports) for use with a nested telescoping apparatus (e.g., a flexible tubular member).
  • FIG. 19A shows the apparatus in a stored configuration, prior to loading the nested telescoping apparatus.
  • FIGS. 19B-19D show setup of the link assembly including supports to receive the nested telescoping apparatus.
  • FIGS. 19E-19H illustrate loading of the nested telescoping apparatus onto the apparatus.
  • FIG. 19H shows the pre-deployed configuration with the nested telescoping apparatus attached and in a stored configuration ready for positioning relative to a patient.
  • FIGS. 19A-19H illustrate one example of the preparation of an apparatus including a link assembly and supports (e.g., flexible tubular member supports) for use with a nested telescoping apparatus (e.g., a flexible tubular member).
  • FIG. 19A shows the
  • FIGS. 20A-20I illustrate operation of the supports as the nested telescoping apparatus is inserted and/or withdrawn.
  • the supports are moved in or out of the insertion axis as needed to support the nested telescoping apparatus.
  • FIGS. 21 A and 21B show side and front views, respectively, of a portion of an apparatus, including a link assembly with supports, as described herein. In this configuration of the link assembly and supports, two of the supports are shown in a stored configuration, folded out of the plane of the insertion axis.
  • FIG. 22 shows another view (e.g., side view) of an apparatus similar to that shown in FIGS. 21A-21B, including a nested telescoping apparatus shown schematically illustrated in a pre-loaded configuration ready to be positioned and deployed relative to a patient.
  • FIG. 23 is an enlarged view of the connection region of two of the supports of the apparatus showing connection to the link assembly.
  • FIG. 24 schematically illustrates an example of an optical sight (sighting device) that may be incorporated into any of the apparatuses described herein to assist in aligning the insertion axis of the apparatus with the patient.
  • aspects of the present disclosure may be integrated into a robotically-enabled medical system capable of performing a variety of medical procedures, including both minimally invasive procedures - such as laparoscopy - and non-invasive procedures - such as endoscopy.
  • the system may be capable of performing colonoscopy, enteroscopy, bronchoscopy, ureteroscopy, gastroscopy, etc.
  • the system may provide additional benefits, such as enhanced imaging and guidance to assist the physician.
  • the system may provide the physician with the ability to perform the procedure from an ergonomic position without the need for awkward arm motions and positions. Still further, the system may provide the physician with the ability to perform the procedure with improved ease of use such that one or more of the instruments of the system can be controlled by a single user.
  • An apparatus e g., a system, devices, etc.
  • for operating and/or deploying a robotic scope may be configured extend (distally) and/or retract (proximally) to control operation of the flexible tubular member.
  • these apparatuses may be used to deliver a flexible tubular member, including in particular, a nested endoscope that include both an outer “overtube” an inner endoscope that may be moved proximally/distally relative to each other and may each be rigidized to guide and/or steer the device through the patient’s body.
  • These apparatuses may include a telescoping set of links, and in particular vertically-arranged links.
  • the apparatuses (device, systems, etc.) described herein may be configured as a portion of a robotic system for delivery of a pair of a nested endoscope device, including an inner endoscope and an outer overtube, that are each capable of relatively high and low levels of compliance.
  • the apparatuses described herein may have a generally linear form factor, and may therefore provide a linear kinematic system for delivery of devices.
  • the primary linear axis that may position the apparatus (e.g., the overtube of the endoscope) into the patient includes a telescoping mechanism formed of a link assembly.
  • the bidirectional telescoping action of this link assembly may allow the relatively long linear axis to be relatively short when its full extension is not needed, which addresses room size limitations in some facilities.
  • the position of the inner endoscope relative to the outer overtube may be controlled by an independent linear axis.
  • these apparatuses may be used with virtually any flexible tubular member, they may be particularly helpful when using a nested, and in particular rigidizing, endoscope, such as a dual rigidizing endoscope.
  • FIGS. 1A-1D illustrate one example of a robotic scope configured as a dual rigidizing endoscope.
  • the dual rigidizing endoscope 100 is configured as a nested system including a rigidizable (e.g., rigidizing) outer member 112 and a rigidizable inner member 110.
  • the steerable inner rigidizing member 110 is positioned within the outer rigidizing member 112 such that the distal end of the inner rigidizing member 110 extends outside of the outer rigidizing member. In some cases the inner rigidizing member 110 may be fully retracted into the outer rigidizing member 112.
  • FIG. 1A illustrates one example of a robotic scope configured as a dual rigidizing endoscope.
  • the dual rigidizing endoscope 100 is configured as a nested system including a rigidizable (e.g., rigidizing) outer member 112 and a rigidizable inner member 110.
  • the steerable inner rigidizing member 110 is positioned within the outer rigidizing member 112 such that the distal end of the inner rigidizing member 110 extend
  • IB shows the distal end of the inner rigidizing member 112 is bent slightly in a desired direction/orientation (e.g., via steering cables or other steering mechanism) and then rigidized (e.g., using positive or negative pressure). 112 may also be bent because it was in the flexible state as it followed the curvature of 110, and then was subsequently rigidized.
  • the outer rigidizing member 112 in the flexible configuration
  • the outer rigidizing member 112 is advanced over the rigidized inner rigidizing member 110 (including over the bending distal section). Once the distal end of the outer rigidizing member 100 is sufficiently advanced over the distal end of the inner rigidizing member 110, then the outer rigidizing member 112 can be rigidized (e.g., using positive or negative pressure as described herein).
  • FIG. 1C shows the distal end of the inner rigidizing member 112 is bent slightly in a desired direction/orientation (e.g., via steering cables or other steering mechanism) and then rigidized (e.g., using positive or negative pressure). 112 may also be bent because it
  • the inner rigidizing member 110 can then be transitioned to the flexible state (e.g., by removing the positive or negative pressure in some examples, and by allowing the steering cables to go slack such that tip can move easily) and can be advanced and directed/oriented/steered as desired.
  • the inner rigi dizing member 110 can be actively steered (either manually or via computational control) as it emerges such that is minimizes the load on the rigidized outer tube. Minimizing the load on the outer rigidizing member may make it easier for this tube to hold the rigidized shape.
  • the outer rigidizing member 112 can be transitioned to the flexible state and advanced thereover.
  • the process can then be repeated to navigate through even more tortious anatomies.
  • it may be particularly difficult to coordinate the movement of the inner and outer members, including advancing/retracting and selectively rigidizing either the inner or outer or both, making a robotically controlled system particularly advantageous.
  • the repeated process can result in “shape copying,” whereby the inner and outer rigidizing members, while in a flexible configuration, may continuously conform to (or copy) the shape of whichever member is in the rigid configuration.
  • FIGS. 1A-1D illustrate the operation of just one type of medical instrument that may be used with the methods and apparatuses described herein.
  • these apparatuses may be configured so as to function as endoscopes, including one or more of imaging, irrigation, lighting, steering channels for removing or applying materials, etc.
  • the robotic scope 100 may be a “navigation” device comprising a camera, lighting and a distal steering section.
  • the navigation device (scope or portion of a scope) may be well sealed such that it is easy to clean between procedures. In some examples it does not need to be cleaned because it is fully sheathed, including both on the outside and through the working channels.
  • a second inner device may then be placed inside the rigidized outer member and advanced past the distal end of the outer member.
  • the second inner member may be a “therapeutic” tube comprising such elements as a camera, lights, water, suction and various tools.
  • the “therapeutic” device may not have a steering section or the ability to rigidize, thereby giving additional room in the body of the therapeutic tube for the inclusion of other features, for example, tools for performing therapies.
  • the tools on the “therapeutic” tube may be used to perform a therapy in the body, such as, for example, a mucosal resection or dissection in the human GI tract.
  • each rigidizing member described herein can transition from a flexible configuration to a rigid configuration and the stiffness may be considered “variable stiffness” as it may be selected by the user or system.
  • each rigidizing member may be rigidized by applying a positive or negative pressure to the wall of the rigidizing member or within the wall of the rigidizing member. With the positive or negative pressure removed (or reversed), the layers can easily shear or move relative to each other; the release of the positive or negative pressure may allow the layers to transition to a condition in which they exhibit a substantially enhanced ability to resist shear, movement, bending, torque and buckling, thereby providing system rigidization.
  • the methods and apparatuses described herein may be used with any appropriate rigidizable member(s), not limited to positive or negative pressure rigidizing apparatuses.
  • the rigidizable members described herein may refer to any appropriate rigidizing device, including members that may be rigidized by jamming particles, by phase change and/or shape memory alloys, by interlocking components (e.g., cables with discs or cones, etc.), EAP (electro-active polymers) or any other rigidizing mechanism.
  • any of the rigidizable apparatuses described herein may include rigidizing layers or regions that engage with a compression layer (which may be or may include a bladder) that applies force to the rigidizing layer to rigidize the rigidizing layer or in some cases to de- rigidize (e.g., release from rigidization) the rigidizing layer.
  • these rigidizable apparatuses may include a rigidizing layer that could include a braid, knit, woven, chopped segments, randomly distributed or randomly oriented filaments or strands, engagers, links, scales, plates, segments, particles, granules, crossing filaments, or other materials forming the rigidizing layer.
  • the rigidizing layer may comprise multiple strand lengths or strand segments that cross over each other (e.g., as part of a braid, knit, woven, etc.); the compression layer may apply force to drive the crossing strand lengths or strand segments against each other.
  • the examples shown herein are braids, any of these apparatuses may instead or in addition include a general rigidizing layer comprising crossing strand lengths or strand segments.
  • the examples of rigidizing apparatuses described herein may use pressure (positive pressure) and/or negative pressure to selectively and controllable rigidize. In some examples the method described herein may be used with any appropriate rigidizing apparatus.
  • FIGS. 1 A-1D A sequence identical to or similar to that illustrated in FIGS. 1 A-1D may be performed by the apparatuses described herein, including in particular, the rotational systems described herein.
  • the robotic scopes may be actively steered automatically or manually, including by a user operating the apparatus, so that the robotic scope is steered into known, assumed, or measured shapes, when advanced into the anatomy. This may be particularly useful and important when navigating a dual rigidizing endoscope such as (but not limited to) that shown in FIGS. 1A-1D.
  • a distal tip of the inner rigidizing member can be steered (including steering to set or match a shape of the section of the outer rigidizing member).
  • a region of the inner and/or outer members of the scope may be steered at a region immediately proximal to the distal tip.
  • the apparatuses described herein may include effectors for controlling operation of the scope operated by the device, including for steering, rigidizing, navigation, imaging, lighting, etc.
  • the effectors e.g., end effectors
  • the effectors of some variations of the system's robotic arms may include an instrument driver that may incorporate electro-mechanical means for actuating (e.g., steering) the medical instrument and may include a mount assembly for detachably coupling to the scope or portion of the scope (e.g., inner member, outer member, etc.).
  • PCT application PCT/US2023/064999 filed March 27, 2023, and titled “METHODS AND APPARATUSES FOR NAVIGATING USING A PAIR OF RIGIDIZING DEVICES,” describes examples of apparatuses including nested apparatus that may be used with any of the methods and apparatuses described herein.
  • Other examples of apparatuses that may be used with the methods and apparatuses described herein may include nested catheters such as those described, for example, in U.S. patent application no. 17/902,770, tiled “NESTED RIGIDIZING DEVICES,” filed on September 8, 2022, U.S. patent application no. 18/000,062, titled “RIGIDIZING DEVICES,” filed on May 26, 2021, patent application no.
  • the robotic scope such as a dual rigidizing apparatus shown in FIGS. 1A-1D may be robotically controlled.
  • the proximate end(s) of the robotic scope may include connection for connecting the robotic scope to a frame.
  • the outer rigidizing member 112 and the inner rigidizing member 110 may each include controls and/or connections for coupling to steering inputs, air lines (e.g., suction), water lines, video lines (e.g., monitors, et.), and/or one or more tool channels.
  • each of the inner and outer members may include a connector region, such as a cassette 257, shown schematically in FIG. 2.
  • a cassette 257 shown schematically in FIG. 2.
  • Each of the inner and outer members may include a separate cassette.
  • the cassette may include connections for controlling steering, e.g., by one or more steering tendons, within the inner and/or outer members.
  • the cassette 257 can include disks 271a, 271b that may connect to cables 263a, 263b respectively, to steer (e.g., bend or deflect) the tip of the inner rigi dizing member 210.
  • Other steering mechanisms e.g., pneumatics, hydraulics, shape memory alloys, EAP (electro-active polymers), or motors
  • one or more disks in the cassette 257 may be used to actuate the steering.
  • the cassette 257 can further include pressurization connections 203a, 203b that may connect to a pressure source for rigi dizing the inner and/or outer members, respectively.
  • Pressure positive or negative, depending on the robotic scope, may pass through pressure lines 205z, causing the pressure in a pressure gap of the inner rigi dizing member 210 to change (e.g., increase under positive pressure or decrease under negative pressure, i.e. vacuum), causing the rigi dizing devices 210, 212 to become rigid.
  • Activation of the pressure (positive or negative) may be applied sequentially and/or simultaneously, as illustrated in FIGS. 1A-1D.
  • the cassette 257 can include pressure connectors 274a, b to sealingly couple to the one or more pressure sources.
  • Other mechanisms causing rigidization of the robotic scope e.g., inner and outer rigidizing members are also possible.
  • the cassette 257 can include a connector for connecting to additional lumens and/or wiring in the outer or inner rigidizing device(s).
  • the cartridge 257 is coupled to the inner rigidizing member 110 and the connector 225y may include a connection for the delivery of both suction and water to the tip of the inner rigidizing device.
  • the connector 225y may include an electrical connector to connect to a camera mounted to the tip of inner rigidizing device 110 to an external monitor and/or video processing unit.
  • the connector 225y may include a mechanical connector that connects to a hollow tube (e.g., working channel) leading all the way to the tip of the inner rigidizing device 210.
  • control connections may be accessible from a bottom of the cassette 257.
  • the control connectors may have features, such as splines, pins or teeth, to transmit torque. These features can allow them to be manipulated (e.g., by a drive system/sub- system).
  • the drive system may be part of the link assembly described herein or it may be integrated with the link assembly.
  • the same controller may operate the drive assembly and the other components of the apparatus (e.g., linear drive for the link assembly, height adjustment, pitch, etc ), including the rigidizing/derigi dizing control.
  • FIGS. 3A and 3B schematically illustrate a first example of an apparatus (e.g., system) for deploying and/or controlling a flexible tubular member.
  • the apparatus is shown to be configured for use with a flexible tubular member configured as a nested endoscope that includes both an outer “overtube” an inner endoscope that may be moved proximally/distally relative to each other and may each be rigidized to guide and/or steer the device through the patient’s body (as described above).
  • these apparatuses may be used with any flexible tubular member, including those that are not nested and that do not rigidize (e.g., single-body endoscopes).
  • the system 300 shown includes a base that my support the weight of the rest of the system, including any flexible tubular member attached to the system.
  • the base 341 may be weighted so as to allow the telescoping link assembly and any attached flexible tubular member to cantilever distally or proximally away from the base, while remaining stable.
  • the base may house one or more additional components, including power source, power conditioners, motors, pressure source/pressure supplies, controllers, control circuitry, etc.
  • the base 341 may include wheels 351 to allow the apparatus to be moved and positioned relative to a patient’s bed.
  • the base 341 may include an anchoring region 353 that may be lowered and/or raised to allow or prevent movement.
  • the wheels may be locking or lockable.
  • FIG. 3 A shows the link assembly 301 configured as a vertically arranged link assembly including three links: a first link 305 (e.g., outer link or base link which may be coupled to the base), a second link 307 (e.g., an intermediate link) and a third link 309 (e.g., inner link).
  • the first link is coupled to the yaw adjust arm 337 that is also configured as (or may be coupled to) a vertical lift arm 335 connecting the link assembly 301 to the baes 341.
  • the system 300 shown in FIG. 3A also includes a mount assembly comprising a pair of mount regions 323, 333 that are coupled to the third link.
  • the first mount region 323 is configured as an overtube mount for coupling with an overtube of an endoscope.
  • the overtube mount is located at or near the distal end region of the third link and includes an overtube drive assembly (e.g., driver) 321 that may interface with the overtube of the endoscope.
  • the overtube drive assembly may include drive components for controlling roll, for steering (optionally, in examples in which the overtube may be steered at the distal end), and/or pressure inputs/outputs for rigidizing/de-rigidizing.
  • the overtube mount 323 may be configured to secure to the overtube portion separately from the inner endoscope. In some examples the overtube mount 323 may secure by including a securing mechanism such as a clamp, clasp, latch, lock, etc.
  • the second mount region 333 is configured as an inner endoscope mount and may also include an inner endoscope drive assembly 331, as shown.
  • the inner endoscope drive assembly (driver) may interface with the inner endoscope member and may include the drive components described above in reference to FIG. 2, including steering components (e g., for steering the distal end/tip region), roll control, pressure input/output (e.g., for rigidizing/de- rigidizing, etc.).
  • the inner endoscope mount 331 may be configured to secure to the inner endoscope separately from the overtube, e.g., by including a securing mechanism such as a clamp, clasp, latch, lock, etc.
  • FIG. 3C shows another example of a robotic system 300’ including a telescoping link assembly 301 and base 341 similar to that shown in FIGS. 3A-3B.
  • This example also includes a flexible tubular member attached to the system.
  • the flexible tubular member in this example is configured as a nested pair of rigidizing devices similar to those shown in FIGS. 1A and IB, including an outer overtube 312 and an inner endoscope 310.
  • the base 341 supports the telescoping link assembly 301 and the attached endoscope, so that the link assembly may smoothly move from a relatively low footprint centered neutral configuration to either a partially or fully extended configuration (as shown in FIG. 3B) or a partially or fully retracted configuration, as shown in FIG. 3C.
  • the flexible tubular member may extend distally.
  • the apparatus may include one or more supports to prevent buckling or collapse of the flexible tubular member.
  • the link assembly 301 is configured as a vertically arranged link assembly, although any orientation of links may be used (e.g., horizontally-arranged, angled, hybrid horizontal/vertical/angled, etc.). Although three links 305, 307, 309 are shown, any number of links may be included.
  • the flexible tubular member is coupled to the mount assembly coupled to the inner-most (third) link 309.
  • the mount assembly includes a first mount region 323 to which the proximal end region of the overtube 312 is coupled.
  • the first mount region may include a drive assembly 321 including one or more actuators for actuating movement of the elongate flexible member (e g., overtube).
  • the first mount region 323 may include one or more roll actuators for rolling the overtube relative to the inner endoscope.
  • the overtube may be steerable, e.g., by including one or more steering members (e.g., pull wires, tendons, etc.).
  • the first mount region may include actuators for actuating the steering of the overtube.
  • the overtube may be connected to a source of pressure (e g. positive and/or negative pressure) for rigidizing/derigidizing the overtube.
  • the first mount assembly may include a pressure port and may be configured to couple the overtube to the source of pressure.
  • the source of pressure may be included with the system, or the system may be configured to couple to the source of positive and/or negative pressure.
  • the inner endoscope of the flexible tubular member is also connected to the mount assembly, by connection to the second mount region 333.
  • the second mount region may include a second drive assembly 331 including one or more actuators for actuating the flexible tubular member (e g., inner endoscope).
  • the second mount region 333 may include one or more roll actuators for rolling the inner endoscope relative to the overtube.
  • the inner endoscope may be steerable, e.g., by including one or more steering members (e g., pull wires, tendons, etc.).
  • the second mount region may include actuators for actuating the steering of the inner endoscope.
  • the inner endoscope may also be connected to a source of pressure (e.g. positive and/or negative pressure) for rigidizing/derigidizing the inner endoscope.
  • the second mount assembly may include a pressure port and may be configured to couple the inner endoscope to the source of pressure.
  • the mount assembly may generally be configured to move the first mount region and the second mount region relative to each other, and therefore move the overtube and the inner endoscope relative to each other.
  • the inner endoscope may be withdrawn partially or fully into the overtube may extend some distance out of the overtube (as shown in FIGS. 3C and 3D).
  • FIG. 3D shows a top view of the system 300’ of FIG. 3C.
  • the mount assembly (e.g., in some examples a first mount region and a second mount region) may be configured to secure to the flexible tubular member generally.
  • the mount assembly may be configured to releasably couple to the flexible tubular member by one or more securing mechanisms such as clamps, clasps, latches, locks, etc.
  • the mount assembly may be configured to separately couple the first mount region of the mount assembly to the overtube, and the second mount region may be configured to separately couple to the inner endoscope.
  • FIG. 5A shows the link assembly of the apparatus in a fully proximal, retracted configuration.
  • FIG. 5B shows the link assembly of the apparatus in a fully distal, extended configuration.
  • the inner endoscope mount 333 may be configured to move distally or proximally relative to the overtube mount (and the link assembly). In some examples the inner endoscope mount 333 may move relative to the outer overtube mount 323, as will be described in FIGS. 5A-5B, below.
  • FIG. 4 shows an example of a system 400 similar to that shown in FIGS. 3 A-3B, in which the link assembly (including first 405, second 407 and third 409 links) moved in a proximal to distal direction when extending and retracting. Insertion and retraction may be driven by an overtube insertion motor 415 (e g., a linear drive, such as a ball screw/nut assembly).
  • the overtube mount 423 also includes an overtube roll motor 426.
  • the inner endoscope mount 433 includes an endoscope driver 431 including an endoscope roll motor 435 and multiple steering motors 437.
  • the link assembly is pivotally attached to a yaw adjustment arm 337 (which may be coupled to the base link 305 either directly or indirectly) and a vertical lift arm 335.
  • the mount assembly for the flexible tubular member may include one or more separated drives for driving relative movement of an outer (e g., overtube) and inner (e.g., inner endoscope) member of the flexible tubular member.
  • FIGS. 5A-5B illustrate one example of a vertically-arranged link assembly that includes a mount assembly including an overtube mount 523 and a separately actuating inner endoscope mount 533. These regions of the mount assembly are configured to operate together, to provide relative motion between the first and second regions. The regions may be directly or indirectly coupled together. For example, in FIG. 5 A and 5B both the first mount region (the overtube mount 523) and the second mount region (endoscope mount 533) forming the mount assembly are coupled to the third link 590.
  • the vertically-arranged link assembly 501 includes a first link 505 (e.g., a base link), a second link 507 and a third link 509 that are vertically arranged relative to each other and are separated by shuttles (e.g., first shuttle 519 and second shuttle 518), that may be coupled to one or more bands and/or belts to permit them to coordinate extending and retracting.
  • the mount assembly e.g., first mount region and second mount region, are coupled to the third link.
  • the first mount region 523 for the overtube is rigidly (e.g., fixed) coupled to the third link 509 and also includes an overtube driver (e.g., overtube roll motor 526) to drive roll of the overtube in the clockwise and/or counterclockwise direction.
  • the second mount region 533 for the inner endoscope is proximal to the first mount and is configured to moved distally/proximally along an endoscope inserting track 569, and includes one or more drivers for operating the inner endoscope, such as an inner endoscope roll motor 535 and/or inner endoscope steering motors 537.
  • the third link may include a drive for driving the second mount region.
  • FIG. 5A the second mount region is shown fully distally relative to the first mount region; in FIG. 5B the second mount region is shown fully proximally relative to the first mount region.
  • FIGS. 6A-6D shows another example of a vertically-arranged link assembly 601 similar to that shown in FIGS. 5A-5B, illustrating an intermediate configuration of the set of vertically-arranged links.
  • any of the apparatuses described herein may include more than three links; for example, these apparatuses may include four links, five links, six links, etc.
  • the additional links may be configured and controlled as shown here for three links.
  • the outer link may be coupled to the base (directly or indirectly) and the inner link may be coupled to the mount assembly (including one or more mount regions).
  • the second and third links are shown as partially transparent,.
  • the motion of the telescoping assembly may be achieved with a single drive (e.g.
  • the motion of the links may be coordinated using bands and/or synchronization belt(s).
  • the bands (and/or belts) may be steel bands. This is also illustrated schematically in FIG. 7A, illustrating the use of two shuttle links (proximal and distal).
  • FIGS. 6B-6D illustrate additional detail of a portion of the vertically-arranged link assembly 601 of FIG. 6A, showing the first link 505 and second link 507 as well as the first shuttle 518 and the second shuttle 519.
  • a pair of thin, flexible bands 655, 656 are shown coupled to the second shuttle 519, which will be positioned between the second link 507 and the third link (not shown).
  • a similar arrangement of flexible bands 655’ are connected between the first link and the second link.
  • the bands 655, 656 are each coupled to the same respective ends of the second 507 and third links via attachment 659, 659’, 659”, and the bands wrap around a pulley surface (e.g., a cylindrical surface 671) in the shuttle 519.
  • the bands may wrap around the pulley surface or different pulley surfaces that may be adjacent to each other.
  • FIGS. 6C and 6D also illustrate one example of a synchronization belt 527 that is shown coupled to the bottom of the second line 507, and to which both the first 618 and second 619 shuttles are coupled.
  • the first shuttle is coupled to the synchronization belt by a bottom attachment 588 that wraps under the second link.
  • the second shuttle is also coupled to the synchronization belt by a bottom attachment 589 that wraps under the second link.
  • the synchronization belt may move (driving coordinated, but opposite movement of the attached shuttles) by rolling about a pair of synchronization pulleys 529, 529’.
  • the first link 705 may support and/or may contain a linear drive 712, shown in this example as a ball screw nut assembly. Rotation of the ball screw 743 drives the linear movement of the ball nut 744.
  • the drive is coupled to the first shuttle 518, which may be coupled through the first link.
  • the first shuttle may be driven proximally and distally by rotating the ball screw clockwise or counterclockwise.
  • the first shuttle is configured to slide between the first link 705 (e.g., a base link) and the second link 707, however a pair of opposing flexible bands 717, 714 are attached to both the first link and the second link and wrap around a cylindrical surface (e.g., a pulley) within the first shuttle 518.
  • a first distal band 717 is attached at a first end 748 to a distal end region of the first link, e.g., on the inside surface facing the second link.
  • the second end 749 of the first distal band 717 is attached to a distal end region of the second link.
  • the first distal band extends between the first and second links and around the cylindrical (e.g., pulley) surface 756 of the first shuttle.
  • the first proximal band 714 is configured similarly, but is oriented in the opposite direction.
  • the first end of the first proximal band which is also a flat ribbon (e.g., a flat metallic ribbon) is attached to the first link at the proximal end region 742, and passes around the cylindrical (e.g., pulley) surface 756 of the first shuttle, where it then connect to the proximal end region 746 of the second link (e.g. on the side facing the first link).
  • the shuttle and the bands are configured to act as a pinon and rack interface between the first and second links.
  • the link assembly may include just a first and second link.
  • a synchronization belt may be used to synchronize the movement of a pair of shuttles. This is illustrated schematically in FIGS. 7B (and FIGS. 7C-7E).
  • FIG. 7B is otherwise similar to FIG. 7A, but includes a synchronization band 727 within the second link 707 that is coupled to both the first shuttle 518 and the second shuttle 519.
  • the synchronization belt 727 may roll about pulleys at either end of the belt and is configured so that movement of the first shuttle 518 proximally result in movement of the second shuttle 519 distally and vice versa.
  • the motion of the first shuttle is synchronized to the middle (second) link via the flexible bands, and to the motion of the second shuttle via the synchronization belt.
  • the motion may be transmitted from the driver (e.g., balls screw) to the flexible tubular member attached to the third link with a ratio of ball screw motion to tip motion that is 4: 1, although other configurations having different ratio could be used.
  • driver e.g., balls screw
  • the bands may also serve as a substrate and/or support for one or more electrical and/or electronic lines (wires, traces, etc.), allowing transmission of control and/or power through the link assembly (e.g., from the first link to the third, or more, links), even as the links move and telescope.
  • the ribbon-shaped flexible bands may therefore provide a relatively constant path length between the links.
  • FIGS. 7A-7E illustrate an example in which both a first distal band 717 and a first proximal band 714 are used, in some examples only a first distal band or a first proximal band may be used.
  • the shuttle may include a channel in which the band is threaded to provide both a proximal and a distal reaction surface for the band; as the shuttle is driven either proximally and distally the band may be driven and slide against either reaction surface to move the second link.
  • FIGS. 7C-7E illustrate an example showing the operation of a set of three links of a vertically-arranged link assembly.
  • the first link 705 includes (e.g., at least partially houses) the drive, e.g., the ball nut 744 and the ball screw 743, moving the first shuttle 518.
  • a first distal band 717 and a first proximal band 714 extend between the first link 705 and the second link 707 and around the cylindrical surface of the first shuttle in opposite directions.
  • the third link 709 is similarly connected to the second link 707 via a second distal band 712 and a second proximal band 716 that curves around a cylindrical surface (e.g., pulley) of the second shuttle 519.
  • first shuttle and the second shuttle are both coupled to a synchronization belt 727 within or coupled to the second link.
  • the second and third links are each driven proximally, as shown.
  • the second and third links are each driven distally in a coordinated telescoping movement.
  • FIGS. 7C-7E show a top view (looking down) of the vertically-arranged link assembly, and are not necessarily drawn to scale.
  • FIG. 7C shows the vertically-arranged link assembly in a neutral position, having a relatively compact footprint
  • FIGS. 7D and 7E show the fully telescoping configurations (either proximally or distally, respectively).
  • FIGS. 6A-6D and 7A-7B show the shuttles slidably coupled to the links via a plurality of bands and/or belts
  • any appropriate movement coupling may be used.
  • the shuttles may be moved by a rack and pinion arrangement.
  • FIGS. 7F-7H illustrate another example showing the operation of a set of three links of a vertically-arranged link assembly similar to that shown in FIGS. 7C-7E, however the link movement is synchronized using a ball screw actuator rather than a synchronization band.
  • the telescoping movement of the links may be synchronized using any appropriate movement-synchronizing mechanism, including a band, ball-screw, etc.
  • the first link 705 includes (e.g., and may at least partially house) the drive, e.g., a ball nut 744 and the ball screw 743, moving the first shuttle 518.
  • a first distal band 717 and a first proximal band 714 extend between the first link 705 and the second link 707 and around the cylindrical surface of the first shuttle in opposite directions.
  • the third link 709 is similarly connected to the second link 707 via a second distal band 712 and a second proximal band 716 that curves around a cylindrical surface (e.g., pulley) of the second shuttle 519.
  • the first shuttle and the second shuttle are both coupled to a ball screw actuator 787 within or coupled to the second link.
  • FIGS. 7F-7H show a top view (looking down) of the vertically-arranged link assembly, and are not necessarily drawn to scale.
  • FIG. 7F shows the vertically-arranged link assembly in a neutral position, having a relatively compact footprint
  • FIGS. 7G and 7H show the fully telescoping configurations (either proximally or distally, respectively).
  • FIGS. 7F-7H illustrate another example showing the operation of a set of three links of a vertically-arranged link assembly similar to that shown in FIGS. 7C-7E, however the link movement is synchronized using a ball screw actuator rather than a synchronization band.
  • the telescoping movement of the links may be synchronized using any appropriate movement-synchronizing mechanism, including a band, ball-screw, etc.
  • the first link 705 includes (e.g., and may at least partially house) the drive, e.g., a ball nut 744 and the ball screw 743, moving the first shuttle 518.
  • a first distal band 717 and a first proximal band 714 extend between the first link 705 and the second link 707 and around the cylindrical surface of the first shuttle in opposite directions.
  • the third link 709 is similarly connected to the second link 707 via a second distal band 712 and a second proximal band 716 that curves around a cylindrical surface (e.g., pulley) of the second shuttle 519.
  • the first shuttle and the second shuttle are both coupled to a ball screw actuator 787 within or coupled to the second link.
  • FIG. 7G when the linear drive drives the first shuttle proximally 748, the second and third links are each driven proximally, as shown.
  • FIG. 7E when the linear drive drives the first shuttle distally 746, the second and third links are each driven distally in a coordinated telescoping movement. This actuation scheme may be repeated two or more times in series to achieve the movement.
  • FIGS. 7F-7H show a top view (looking down) of the vertically-arranged link assembly, and are not necessarily drawn to scale.
  • FIG. 7F shows the vertically-arranged link assembly in a neutral position, having a relatively compact footprint
  • FIGS. 7G and 7H show the fully telescoping configurations (either proximally or distally, respectively).
  • FIGS. 71- 7K illustrate another example showing the operation of a link assembly also configured for bidirectional telescoping movement of a set of links of a link assembly similar to that shown in FIGS. 7C-7E and 7F-7H , however the link movement is synchronized using plurality of mechanical movement coupling members, comprising a ball screw actuator in this example.
  • This configuration does not include a separate synchronization band.
  • the telescoping movement of the links may be synchronized by operation of the ball screws to which each stage is coupled to the adjacent stage.
  • all of the bands have been replaced with ball-screw actuators and the shuttles are instead additional intermediate links. This may accommodate the stroke of the ball screws.
  • the ball screws/nuts may be biased to the ends of the links in the nominal (centered) position, as shown in FIG. 71.
  • the first link 705 includes (e.g., and may at least partially house or is coupled to) the drive, e.g., a ball nut 744 and the ball screw 743, moving the first intermediate link 707” that also houses or is otherwise coupled to a ball nut 744’ and ball screw. This pattern may be repeated for the second 707’ and third 707 intermediate links.
  • the drive e.g., a ball nut 744 and the ball screw 743
  • the top links when the linear drive drives the first shuttle proximally 748, the top links are each driven proximally, as shown; the links may be arranged so they extend over the top of the bed/table but by a minimal amount to allow maneuvering near the patient.
  • the top links when the linear drive drives the first shuttle distally away from the patient 746, the top links (third link 709 and intermediate link 707) are each driven distally in a coordinated telescoping movement.
  • the assembly of liner links may be any appropriate size and may be configured to give a working range of movement during operation.
  • the apparatus may be configured to sweep the overtube (outer member of the telescoping assembly) over a length of between about 0.2 m and 3 m, e.g., between about 0.5 m and 2.2 m, etc., in variations in which the overtube mount 523 is fixed to the first link (this range may be larger if the overtube mount may move relative to the link assembly).
  • FIG. 7L shows a top view of an example of an assembly of linear links of a robotic apparatus, including exemplary dimensions.
  • both extension to the right 746 e.g., distal extension
  • extension to the left 748 e.g., proximal extension
  • the distance between the cart (base) front and the proximal end of the first link 709 maybe, e.g., between 0.25 and 2 meters; in the specific, non-limiting example shown in FIG. 7L, the distance is shown as about 1.69 m, thus the maximum proximal extension is about 1.6 m.
  • the maximum range of motion (ROM) of the overtube mount, and therefore the proximal end of the overtube is shown as about 1.953m, thus the sweet length of the inner member (e.g., the inner endoscope mount 533) is about 2.57m.
  • each link may be moved by a driver (e.g., motor, etc.) that may be integrated (e.g., coupled, contained within, etc.) to the link.
  • a driver e.g., motor, etc.
  • integrated e.g., coupled, contained within, etc.
  • FIG. 8 illustrates one example of a method of using a system 800 for deploying and/or controlling a flexible tubular member as described herein, including a vertically- arranged link assembly 801 that is schematically shown engaged with an endoscope 890 to deploy and control the endoscope as it is inserted into a patient 881.
  • the patient is shown lying on his side on a table 882.
  • the device is initially positioned at the foot of the bed, and the system must hold the endoscope, which has a length of about 1.5 meters, initially outside of the patient’s body before being inserted into the patient’s rectum, to perform a colonoscopy.
  • the links of the vertically-arranged link assembly 801 are arranged perpendicular to the ground, and may telescope distally initially (as shown) to provide sufficient clearance outside of the body, while still allowing the system to be placed adjacent to the edge of the table/bed 882.
  • the vertical arrangement of the links allows the endoscope device to be positioned in-line with the patient at the height of the insertion point.
  • this configuration may have a minimal distance from the device axis (e.g., endoscope axis) to the top of the bed mattress.
  • the configurations described herein may instead by used with the links arranged horizontally (e.g., in parallel with the ground), as shown in FIG. 9.
  • the system 900 includes a set of horizontally arranged linear links 901 that may engage with the proximal end of an endoscope 990 (e.g., robotic, rigi dizing endoscope, as described herein).
  • an endoscope 990 e.g., robotic, rigi dizing endoscope, as described herein.
  • the device may be retracted and extended, as described above for the vertically-arranged link assembly, but proximal advancement of the device may receive interference from the bed 982 (e.g., mattress), limiting the approach angle when inserting into the patient 981.
  • FIGS. 10A-10C illustrate representative distance between the device axis (e.g., long axis of the endoscope) and the top of the table or mattress (e g., bed) relative to the patient anatomy.
  • FIG. 10A illustrate the patient and bed position and dimensions for a lower GI, left lateral approach.
  • the patient is shown on their side on the bed 982, in a patient longitudinal position 1075.
  • the device axis 1078 needed for insertion into the rectum from this position requires a height above the bed as shown 1076, which may be within an average range. This height may be significantly higher than the height for a lower GI, supine approach, as shown in FIG. 10B.
  • the patient is lying in a longitudinal position 1075’ on their back, and the height of the device axis 1078’ above the bed 1076’ is lower than in 10A.
  • FIG. 10C illustrates an example of an upper GI procedure using this system, in which the patient is in a left lateral position (prone and supine, with their head turned approximately 90 degrees).
  • the device axis 1078” for accessing the patient’s mouth is typically about the height of the patient’s head above the mattress 1076”.
  • any of these systems and apparatuses may be configured for use with a drape, shield or screen to prevent contamination or soiling of the apparatus
  • FIG. 11 schematically illustrates an example of draping a system as described herein to limit soiling of the device by patient fluids, which may help minimize cross-contamination between patients.
  • these systems may be draped as shown to from a non- sterile barrier to minimize soiling or excessive soiling of the robotic system.
  • the draping 1193 may be configured to provide a sanitary but not sterile cover for the system, including the base and/or the link assembly 1101 (e.g., the vertically-arranged link assembly).
  • the draping may be two or more parts, as shown, including a first part that covers the base and a second part that covers the link assembly.
  • the system, or at least the vertically-arranged link assembly may be covered with a sterile drape.
  • any of these apparatuses and methods may include sterilizing and/or wrapping in a sterile outer cover.
  • any of these apparatuses may include a support arm 1176 that may extend from the vertically-arranged link assembly 1176, as shown in FIG. 11 and in FIG. 12.
  • the endoscopes described herein may prevent or limit the buckling of the endoscope under compressive loads.
  • the system 1200 includes a vertically-arranged link assembly 1201 from which an elongate support arm 1276 may extend and may engage with an endoscope 1290 as just discussed, to prevent or inhibit buckling.
  • the support arm 1276 may include multiple supports for the devices along their length to provide parallel paths to mechanical ground. These supports could be passive (sliding/rotating) or motorized.
  • a laser pointer can be attached to an anti -buckling support, or another distal part of the machine.
  • FIG. 13 illustrates different movement and adjustment axes for a device similar to that shown in FIGS. 3A-3B and 4, above.
  • the system includes a base 1341, and wheels 1351, that support the arm (e.g., column, shaft, etc.) 1335 and may change the relative position of the linear link assembly to the base.
  • the height of the link assembly may be adjusted in the vertical axis 1335’, e.g., using a vertical lift 1335 as shown.
  • the angle of the vertically-arranged link assembly relative to the bed or patient may be adjusted, e.g., by rotating the vertically-arranged link assembly about the yaw axis 1337’.
  • the position of the link assembly may be adjusted prior to performing the procedure with the system.
  • the position the telescoping robot relative to the cart may be adjusted for ether yaw and/or vertical.
  • These axes can be locked out intraoperatively.
  • these axes can also be put into a floating state to enable intraoperative patient repositioning.
  • the cart wheels can be unlocked and/or locked, to allow planar positioning of the robot relative to the patient.
  • one or more additional tools may be included and/or mounted to the system, including to the link assembly 1401 (e.g., vertically oriented link assembly) to assist in manipulating multiple different end effectors that may be used with the endoscope, including inserting and or operating though a working channel of the endoscope.
  • the endoscope may include an entry point in the Endoscope Handle for a tool that goes into an Internal Working Channel (IWC) of the endoscope.
  • IWC Internal Working Channel
  • a 9 th robot axis that controls the insertion depth of this tool may be used.
  • DOFs degrees of freedoms
  • FIG. 14 shows a schematic of a generic internal working channel (IWC) tool 1462 for entry into a working channel.
  • the device 1462 may be coupled to the mount assembly on the link assembly 1401, as shown and may engage with the mount assembly (on in some case the second mount region and/or first mount region) for operation.
  • these apparatuses may be used with a variety of procedures.
  • these systems 1500 may be used as part of a lower GI procedure, as shown in FIGS. 15A-15C.
  • the system 1500 including a vertically arranged linear link assembly 1501 may be used with a patient 1581 virtually any orientation on the bed/cart 1582.
  • the system may be positioned on the foot of the patient’s bed.
  • FIG. 15A shows the patient in a side-facing position.
  • FIG. 15B shows a top view of a colonoscopy procedure as described above.
  • the flexible tubular member is part of a system 1500 and is inserted and manipulated using a vertically arranged linear link assembly 1501.
  • FIG. 15C the patent 1581 remains approximately the same, and the angle of approach may be adjusted, as shown.
  • Any of these apparatuses may also or alternatively be used as part of an upper GI procedure, as shown in FIGS. 16A-16B.
  • the cart for the system 1600 is positioned at a side the bed 1682 so that the flexible tubular member held by the link assembly may be used to insert, manipulate and retract the flexible tubular member into the patient’s body.
  • any of the apparatuses described herein may include one or more supports to prevent collapse or other unintended movement of the flexible tubular member during dispensing/deploying (insertion and/or retraction), including in particular during deploying of a nested telescoping apparatus, which may include an overtube nested with an endoscope.
  • one or more supports (“supports,” “endoscope supports” or “anti-buckling supports”) may be coupled to the link assembly and may be configured to prevent buckling of the flexible tubular member at it extends distally from the link assembly.
  • the flexible tubular member support may be a strut, beam, rod, pole, etc.
  • the flexible tubular member support may include one or more loops or straps for holding (and supporting) a portion of the flexible tubular member.
  • the supports are configured to support the nested apparatus (e.g., endoscope and overtube) during setup and throughout the procedure. This may be accomplished through the use of one or more (e g., 2, 3, 4, 5, etc.) anti-buckling supports, that may be positioned off the distal side of the robotic assembly, and may be part of or coupled to the link assembly. In some cases, when the support(s) is/are not needed to support the nested apparatus, e.g., due to insertion depth, the supports may be configured to move away from the path of the scope and any moving portions of the robot, and/or the bed/table (e.g., gurney) or patient.
  • the nested apparatus e.g., endoscope and overtube
  • the supports may be configured to move away from the path of the scope and any moving portions of the robot, and/or the bed/table (e.g., gurney) or patient.
  • a flexible tubular member support may include a beam or arm that is coupled to and extend from a link of the link assembly.
  • the support may be deflectable so that it may be deflected out of the way when not needed, or in order to prevent interference with another link or portion of the system.
  • the support may be coupled to the link in a movable joint, such as a hinge pivot, ball joint, etc.
  • the movable joint may be biased so that it may return to a predetermined position after it has been deflected and the interfering portion of the system has moved out of the interfering region.
  • the movable joint may be biased to assume a supporting position by a spring or other bias.
  • the portion of the support configure to hold the flexible tubular member may be referred to herein as a seat or seating region.
  • the seat may be configured as a loop, ring, etc., though which the flexible tubular member may be passed.
  • the seat may be open, e.g., on a top region, so that the flexible tubular member may be inserted and removed along its length.
  • the seat may be opened/closed to insert/remove the flexible tubular member.
  • the seat may be configured to allow the flexible tubular member to slide or move therein.
  • the seat may include a lubricious (e.g., slippery) surface to allow sliding of the flexible tubular member relative to the seat.
  • the seat may include a rolling or moving surface (e g., roller, wheel, ball bearing, etc.) to allow movement of the flexible tubular member relative to the seat.
  • FIGS. 17A-17H illustrate operation of one example of a pair of supports coupled to a link assembly.
  • the first support 1730 is coupled to a distal end region the first link 1705.
  • the second support 1730’ is coupled to a distal end region of the second link (e.g. intermediate link).
  • the third link 1709 includes the mount assembly to which the flexible tubular member is attached.
  • the flexible tubular member includes just an outer overtube 1710. As shown in FIG.
  • the first 1730 and second 1730’ supports extend outwards (perpendicular to the anterior/posterior axis) to provide support for the flexible tubular member 1710 that is held in the seats of each support.
  • FIG. 17B the third stage, to which the mount assembly holding the proximal end of the flexible tubular member is connected, is advanced distally, e.g., to insert the flexible tubular member into the body. As it is advanced, the flexible tubular member may slide relative to the supports. In this example, once the links are in approximately the neutral position, as shown in FIGS.
  • the supports 1730,1730’ may pivot out of the way of the adjacent links, and no longer engage with the flexible tubular member. As the flexible tubular member is closer to the patient insertion site, they may no longer be necessary. Alternatively, in some examples the supports may extend proximally and/or over (or in some cases under) the links to avoid interference and may continue to support the flexible tubular member in more distal configurations.
  • FIG. 17E shows the link assembly distally extended, with the seats displaced out of the way of the distally-advanced links.
  • FIGS. 17F-17H illustrate the link assembly moving proximally, so that, as shown in FIG. 17F, the supports may be biased to return back to the extended positions to support the flexible tubular member.
  • the supports may be biased, by a spring, back to a position in which they underly the flexible tubular member as the link assembly is moved proximally, e.g., to retract.
  • the support(s) may extend distally from a link in order to support the flexible tubular member even when the links, including supporting the links when the link assembly is in the neutral (centered) configuration and/or extended distally (e.g., inserted into the patient).
  • the support may include a distally- extending arm segment that may be a fixed length or may be telescoping as the link assembly telescopes.
  • any of the apparatuses described herein may include one or more supports that are configured to support the telescoping apparatus (e.g., the overtube portion of the apparatus) outside of the patient’s body.
  • These supports may be configured to move out of the way of the link assembly as it drives the telescoping apparatus proximally and distally, as just described. In some cases these supports may be configured to be moved in such a manner that they do not interfere with the bed or table on which the patient is positioned. Any of these supports may be configured to be moved to a stored position having a minimal footprint, particularly in the plane of motion of the link assembly.
  • the supports may be configured to have a pre-deployment configuration, in which one or more of the supports may be moved away from the plane of motion of the link assembly, a deployed configuration, in which the supports may be positioned and may be held in the plane of movement to support a portion of the telescoping apparatus outside the patient body, and a postdeployment configuration, in which the one or more supports is moved out of the way of the links as they are moved towards the patient to avoid interference with the operation of the telescoping apparatus.
  • any appropriate number of supports may be included.
  • the supports may be coupled to the links and/or the shuttles.
  • the number of supports may be based on the length of the endoscope to be extended.
  • the supports may be arranged so that they provide a minimum support between every 0.15 m and 0.7 m (e g., between about 0.2 m and 0.5 m, between about 0.25 m and 0.5 m, etc.).
  • This separation distance between the supports may be adjusted based on the properties of the telescoping apparatus (e.g., based on its size, flexibility, etc., and therefore how much support it may need).
  • the distance between the supports may change with operation of the apparatus, e.g., as the telescoping apparatus is inserted/removed.
  • FIG. 18A shows one example of an apparatus including a plurality of supports that may deploy during movement of the links to support a telescoping apparatus (not shown).
  • the apparatus includes four supports 1830, 1831, 1832, 1833 that are shown in the deployed configuration.
  • the first support (support 1 1830) is coupled to the shuttle 1819 between the first link 1805 and the second link 1807. This support may be deployed when the second 1807 and third 1809 links are extended proximally, as shown in FIG. 18 A.
  • the seating region of the first link is in-line with the direction of insertion and/or movement of the link assembly. Otherwise, the support, which include an arm coupled to a seating region, may be rotated down and out of the plane of movement of the links.
  • a bias mechanism e.g., spring, elastic, etc., may drive the support up and into the plane of movement once the second and third links are extended proximally.
  • the first support may be coupled to the shuttle by a pivoting joint that is biased, and one or more cam surfaces may be used to drive the support out of the plane of movement (e g., so that it rotates down and away from links and mounts holding the telescoping apparatus).
  • the first support 1830 includes a pre-deployed configuration in which the arm region rotates the seating region down and away from the link assembly and mount(s).
  • the first support may be driven by a bias the drives the seating region into the plane of movement when the link assembly is fully (or in some cases partially) retracted proximally, e.g., from the pre-deployed configuration to the deployed configuration.
  • the second support 1831 in FIG. 18A is coupled to the second link 1807 on an underside region of a distal end of the second link.
  • This second support also includes an arm region or portion coupled to a seating region.
  • the second support may be coupled to the second link at a first end; the seating region may be at and/or may extend from the second end of the arm region.
  • the arm region of the second support 1831 extends laterally from the second link to position the seating region in the plane of movement (and in-line with the direction of insertion/movement of the link assembly).
  • the second support 1831 is also pivotally connected to the link assembly, e g., to the second link 1807, so that it has a first (e.g., pre-deployed) configuration in which it is rotated down and out of the plane of movement of the link assembly, and a second (e.g., deployed) configuration, in which the second support is rotated up so that the seating region is in the plane of movement of the link assembly, as shown in FIG. 18A.
  • the apparatus may include a bias tending to drive the second support from the pre-deployed configuration to the deployed configuration.
  • the bias may be a spring and/or elastomeric material.
  • the third support 1832 also includes an arm region that is coupled to the second end of the third arm.
  • the arm of the third support includes an elongate length and is configured to extend some distance (e.g., between about 0.1 and 0.5 m, 0.2 and 4 m, etc.) from the proximal end of the first link 1805.
  • the third support may be movably coupled to the first link 1808 of the link assembly so that that it may be moved out into and out of the plane of movement of the link assembly.
  • the third support is shown with the seating region of the third support 1832 in the plane of movement of the link assembly and in-line with the other supports’ seating regions so that these seating regions may all support the telescoping apparatus in a line extending from the mounts as the telescoping device is inserted or retracted.
  • the elongate length (e.g., elongate body) of the support may have curved or bent shape. For example in FIG.
  • the elongate length of the third support 1832 has a bend so that in the post-deployed configuration it is moved both slightly downward (e.g., between 3 and 20 cm, e.g., between 3-12 cm, between 3- 10 cm, less than 10 cm, etc.) and laterally clockwise away from the plane of movement of the link assembly, so that it does not interfere with either the link assembly or the bed/table (e.g., gurney) on which the patient is positioned.
  • the attachment between the elongate body of the third support and the first link of the link assembly may be configured with one or more cam surfaces that direct the movement of the support between the deployed and post-deployed configuration.
  • a bias may be arranged to drive the third support into the deployed configuration (or from the deployed configuration into the post-deployed configuration).
  • the third support may also have a pre-deployment configuration in which the arm of the third support is moved up and out of the plane of movement of the link assembly, as will be described in greater detail below.
  • FIG. 18A also includes a fourth support 1833 that also extends from the first link.
  • the fourth support may extend from the first link on an extendable arm 1836 that can be extended distally or withdrawn proximally from the first link.
  • the extendable arm may be extended and/or retracted manually or automatically.
  • a distal end of the extendable arm may couple to the first end of the fourth support 1833, and may include a pivoting or bending joint similar to that used for the third support.
  • the fourth support also includes a bent or curved arm region and a seating region on the second end of the arm (e.g., arm region).
  • the fourth support arm is bent so that the seating region is in line with the seating regions of the first, second, and third supports when they are in the deployed region.
  • the fourth support art is also configured so that as the link assembly advances the second and/or third link distally the fourth support may also be deflected down and laterally.
  • the fourth support may be deflected slightly downward (e.g., between 3 and 20 cm, e.g., between 3-12 cm, between 3- 10 cm, less than 10 cm, etc.) and laterally clockwise away from the plane of movement of the link assembly, so that it does not interfere with either the link assembly or the bed/table (e.g., gurney) on which the patient is positioned.
  • the downward deflection may be limited so as not to collide with the bed/table surface (e.g. gurney).
  • the fourth support may also be configured to have a pre-deployment configuration in which the arm of the fourth support is moved up (e.g., vertically or approximately vertically) and out of the plane of movement of the link assembly, as will be described in greater detail below.
  • the apparatus may include one or more supports that are movably coupled to the link assembly, so that the support(s) may be moved in- or out- of the plane of movement of the link assembly based the position of the link assembly.
  • Each support may be operably coupled to the link assembly (e.g., a link or shuttle) so that they may be moved into and out of position depending on the configuration of the link assembly.
  • FIG. 18B shows another example of a link assembly including a plurality of supports similar to those shown in FIG. 18A.
  • FIG. 18B also shows examples of spacing dimensions between support, for illustration only. These dimensions are not intended to be limiting and may be different based on the configuration of the link assembly and/or the telescoping apparatus, as mentioned above.
  • a portion of a telescoping apparatus 1810 is shown in FIG. 18B; in practice the telescoping apparatus may extend all the way to and into the body 1890 (e.g., the anus).
  • the supports shown in FIGS. 17A-17H and FIGS. 18A-18B may include an arm region or portion coupled to a seating region.
  • the supports 1830, 1831, 1832, 1833 may each include an elongate and rigid the arm region that is coupled at a second end to a seating region 1830’, 1831’, 1832’, 1833’.
  • the seating region may be flat or may include sides that may retain the telescoping apparatus (e.g., overtube and endoscope), as shown in FIG. 18B.
  • the seating region may form a channel (e.g., an open channel) having sidewalls.
  • the seating region may be configured to allow the telescoping apparatus to slide relative to the seating region.
  • the channel may be lubricious and/or may include one or more moving surfaces (e.g., rollers, bearings, treads, etc.).
  • the seating region may be configured to accommodate sliding as the telescoping apparatus (e.g., overtube) is driven distally and/or proximally by the link assembly (including by the mounts).
  • the telescoping apparatus e.g., overtube
  • the link assembly including by the mounts.
  • ‘seating’ refers to the ability to retain the telescoping assembly in a dynamic (e.g., sliding) manner.
  • the seating region may alternatively be referred to herein as a channel.
  • the seating region may be configured to support the telescoping apparatus even under lateral forces, so that the seating region may prevent the telescoping apparatus from falling out of the seating region.
  • the seating region includes sidewall regions.
  • the seating region may include a cover or retainer that wraps at least partially over the telescoping apparatus while still allowing it to slide in/out (distal/proximal) and vice versa.
  • the sealing region may be configured to include sides that extend approximately 140 degrees or more (e.g., 150, 160, 170, 180, etc.) around the sides of a telescoping apparatus when seated therein.
  • the seating region sidewall has a height that is between 0.4x and 3x the radius of the telescoping apparatus, such as between about 0.5x and 2x, between about 0.6x and 1.5x, etc.
  • the inner surface (e.g., seating surface) of the seating region may be cylindrical, e.g., in some cases having an inner radius that is greater than the outer radius of the telescoping apparatus (e.g., between l.lx and 3x, between l.lx and 2x, etc.).
  • the seating region may have a length that is between 1 mm and 10 cm, e.g., between 0.5 cm and 5 cm, between 0.5 cm and 4 cm, etc.
  • FIGS. 19A-19H illustrate one example of an apparatus including supports being prepared for use with a telescoping apparatus.
  • the apparatus 1900 is shown in an initial, e.g., stored configuration, prior to deployment and prior to attaching the telescoping apparatus.
  • the apparatus includes a link assembly, to which a plurality of fluid lines have been attached, as well as four supports, similar to the examples shown in FIGS. 18A-18B.
  • the third 1932 and fourth 1933 supports are shown in a pre-deployment configuration, in which they are arranged vertically up and out of the plane of movement of the link assembly, providing a more compact configuration.
  • the link assembly is shown in the un-extended configuration in which the inner and intermediate links are aligned with the outer link.
  • the apparatus may include a release catch to release and lower the fourth and/or third support, which may pull past a spring detent to lower arm.
  • the apparatus may be prepared for deployment by attaching the telescoping apparatus (e.g., overtube and endoscope).
  • the link assembly may be retracted proximally, either manually or automatically, by extending the inner link 1909 in a proximal direction, as shown.
  • the fourth support 1933 may then be extended from the out link 1905, as shown in FIG. 19C.
  • Both the third support 1932 and the fourth support may then be moved down (e.g., unfolded) so that the seating regions of the supports are in-line with the seating regions of the first 1930 and second 1931 supports. This is illustrated in FIGS. 19C and 19D.
  • the telescoping apparatus (e.g., overtube and endoscope) may then be attached, as shown in FIGS. 19E-19F.
  • the telescoping apparatus is attached with the overtube coupled at the proximal end to the overtube mount and the elongate, rigidizing, body 1912 of the overtube supported within the seating regions of the supports 1930, 1931, 1932, 1933.
  • FIG. 19E the telescoping apparatus is attached with the overtube coupled at the proximal end to the overtube mount and the elongate, rigidizing, body 1912 of the overtube supported within the seating regions of the supports 1930, 1931, 1932, 1933.
  • the inner member of the telescoping assembly e g., an endoscope or an endoscope covered in a sheath (e.g., a rigidizing sheath)
  • a sheath e.g., a rigidizing sheath
  • the proximal end of the inner member may be coupled to the mount (e.g., inner endoscope mount).
  • the inner member may initially be supported by the fourth support after loading, as shown as shown in FIG. 19G. In FIG. 19Gthe entire assembly is shown loaded and ready for deployment.
  • FIG. 19H shows an example in which the apparatus is preloaded on the robotic assembly as just described, and the supports are moved to the pre-deployment configuration by moving the third and fourth supports in an upright configuration and retracting the link assembly into the compact configuration.
  • the telescoping assembly may held by one or more hooks or other regions on the supports to until the cart including the apparatus can be positioned near the patient and used to control operation of the apparatus.
  • the user may decide how far to retract the system. For example, in some cases the fourth support does not need to be lowered into position, and only the third support arm is lowered for loading. This may depend on the size of the room being used.
  • FIGS. 20A-20I illustrate the operation of the apparatus of FIGS. 19A-19H after installing the overtube and endoscope.
  • FIG. 20A shows the apparatus ready for the patient (e.g., on a gurney) so that the apparatus can be aligned with the patient.
  • the apparatus may be positioned closed to the gurney and patient, initially with the overtube/endoscope in the staged pre-deployed configuration shown in FIG. 19H. Once the patient is in position, the device may be inserted into the patient and operated to robotically (or optionally manually) advance and retracted, including steered.
  • the apparatus may be aligned using a targeting component (e.g., laser) integrated with the apparatus, e.g., in line with the insertion axis for the apparatus.
  • a targeting component e.g., laser
  • the apparatus is inserted into the patient and may be advanced (both the overtube and endoscope) by moving the links of the link assembly from a proximally retracted position (shown in FIG. 20) to a more distal position as shown.
  • the links are moved proximally the elongate body of the overtube 1912 (and endoscope within the overtube) slides distally within the support seating regions.
  • FIG. 20B-20C the apparatus is inserted into the patient and may be advanced (both the overtube and endoscope) by moving the links of the link assembly from a proximally retracted position (shown in FIG. 20) to a more distal position as shown.
  • the links are moved proximally the elongate body of the overtube 1912 (and endoscope
  • the first support 1930 is deflected down and away from the link assembly as it is advanced distally.
  • the second support 1931 is deflected down and away from the link assembly.
  • the overtube/endoscope telescoping apparatus
  • the overtube/endoscope distally causes the third support 1932 to be deflected down, as shown in FIG. 20E and then laterally, as shown in FIG. 20F, so that the support does not interfere with the advancement of the link assembly and the telescoping apparatus.
  • FIG. 20G shows the link assembly extending the overtube/endoscope further distally, until it approaches the fourth support 1933, as shown in FIGS. 20H and 201, causing the fourth support to be driven down slightly, without contacting the table/bed, and then deflecting laterally, as shown in FIG. 201.
  • the same steps may be repeated in reverse as the apparatus is withdrawn proximally, allowing the fourth support to be moved laterally back and rotated back up so that the support seating region is in-line with the insertion/withdrawal axis of the overtube/endoscope, followed by the third support moving laterally back and rotated back up so that the support seating region is in-line with the insertion/withdrawal axis of the overtube/endoscope, then the second support rotating back up so that the support seating region is in-line with the insertion/withdrawal axis of the overtube/endoscope, and the first support rotating back up so that the support seating region is in-line with the insertion/withdrawal axis of the overtube/endoscope.
  • This process may be performed robotically, by one or more drives driving the link assembly as described above, and/or during a manual or manual override procedure.
  • the endoscope may be moved separately from the overtube (and vice versal) by moving the respective mounts.
  • any of these apparatuses may include a pre-deployment configuration in which one or more of the supports are moved out of the plane of movement of the link assembly.
  • FIGS. 21 A and 21B show top and front views, respectively, of an apparatus including a link assembly having four supports, including supports (e.g., the third 1932 and fourth 1933 supports) that are configured to be folded up in the pre-deployment configuration.
  • the third and/or fourth support 1932, 1933 includes a hook or other attachment 2138 that is configured to hold the looped over telescoping apparatus (e.g., overtube/endoscope) in the staged, pre-deployed configuration.
  • the second support 1931 also includes an attachment 2139, shown as an adjacent seating region, for holding the telescoping apparatus (which may be referred to as a staged device tip pocket).
  • the pre-deployment configuration with staging of the telescoping apparatus is shown in FIG. 19H, for example, and in FIG. 22.
  • the telescoping apparatus 2212 is shown with the telescoping assembly in the pre-loaded and stored configuration, ready to be deployed. As described above, this maintains the telescoping assembly ready for deployment so that the entire apparatus, including the link assembly and overtube/endoscope can be positioned adjacent to patient for deployment.
  • the supports 1932, 1933 can be moved down from the stored position shown in FIG. 22 so that the seating regions 1932’, 1933’ are in-line with the insertion/withdrawal axis.
  • FIG. 22 is a rear view that shows the attachment between the supports and the first link of the link assembly; the fourth support 1933 is connected to an extendable arm that extends from the first link. In the stored configuration shown in FIGS. 22 and 23, this extendable arm is retraced into the link assembly and is not visible.
  • the connection for the fourth support 1933 and/or the third support 1932 may include a latch (e.g., support release latch) 2346.
  • the attachment e.g., for the third support, may be retained by a bias or other mechanical and/or electrical/magnetic retainer to prevent accidental deployment.
  • the attachment for the third support to the link assembly includes a spring ball detent 2347 preventing accidental deployment; to deploy the support, the user may apply force to overcome the detent and rotate the support so that the seating region is in-line with the deployment axis.
  • any of the apparatuses described herein may include a targeting guide to assist in aligning the insertion axis of the robot with the patient, e g., with the insertion region on the patient (e.g., the patient’s anus/rectum).
  • a targeting guide to assist in aligning the insertion axis of the robot with the patient, e g., with the insertion region on the patient (e.g., the patient’s anus/rectum).
  • any of these apparatuses may include an optical sight (e.g., laser sight, LED sight, etc.) configured for targeting on the link assembly, e g., on the inner/third link, on one of the supports, on the mount (e.g., endoscope mount, overtube mount, etc.).
  • the optical sight is a low-power (e.g., class I) visible light laser (e.g., red light, blue light, white light, etc.) that projects a beam of light indicating where the insertion axis from the apparatus will contact the patient.
  • the optical sight may be configured to be moved into the insertion axis and/or out of the insertion axis.
  • the optical sight may be moved into (or may be automatically in) position relative to the insertion axis. In some cases this may displace the pre-loaded telescoping assembly of the overtube/endoscope.
  • the optical sight may be used prior to coupling the telescoping overtube/endoscope.
  • FIG. 24 illustrates one example of an apparatus including an optical sight 2452 that is, in this example, coupled to the second support 2431.
  • the second support is configured so that it may be manually or automatically moved, e.g., pivoted, so that the overtube/endoscope is displaced and the optical sight is moved into the insertion axis.
  • the second support may include a pivot 2454 that allows the second support to move the seating region holding the pre-loaded telescoping apparatus (e.g., the overtube/endoscope) into or out of the insertion axis, so that the light 2450 (e.g., laser) is emitted as a beam that will indicate the location of contact with the insertion axis, e.g., on the patient’s body.
  • the optical sight may be moved into position and used to align the apparatus.
  • the projected light may be projected as an image, e.g., of crosshairs.
  • the apparatus may be configured to manually or automatically (or semi- automatically) confirm the targeting to the entry point of the patient.
  • the base of the apparatus which may be moveable, may be locked in position once targeting is confirmed, and the optical sight (e.g., laser) may be turned off and moved out of the way of the insertion axis so that it does not interfere with the overtube/endoscope.
  • the optical sight e.g., laser
  • the apparatus e.g., the optical sight
  • the system may confirm the distance to the patient is sufficient or insufficient (e.g., and that the apparatus should be moved closer/farther from the patient).
  • the nested telescoping apparatus e.g., overtube/endoscope
  • the supports may be wiped down with the rest of the system, and the supports (e.g., the third and fourth support arms may be stowed vertically, as described above).
  • any of the methods (including user interfaces) described herein may be implemented as software, hardware or firmware, and may be described as a non-transitory computer-readable storage medium storing a set of instructions capable of being executed by a processor (e.g., computer, tablet, smartphone, etc.), that when executed by the processor causes the processor to control perform any of the steps, including but not limited to: displaying, communicating with the user, analyzing, modifying parameters (including timing, frequency, intensity, etc.), determining, alerting, or the like.
  • any of the methods described herein may be performed, at least in part, by an apparatus including one or more processors having a memory storing a non-transitory computer-readable storage medium storing a set of instructions for the processes(s) of the method.
  • the device may be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
  • the terms “upwardly”, “downwardly”, “vertical”, “horizontal” and the like are used herein for the purpose of explanation only unless specifically indicated otherwise.
  • first and second may be used herein to describe various features/elements (including steps), these features/elements should not be limited by these terms, unless the context indicates otherwise. These terms may be used to distinguish one feature/element from another feature/element. Thus, a first feature/element discussed below could be termed a second feature/element, and similarly, a second feature/element discussed below could be termed a first feature/element without departing from the teachings of the present invention.
  • any of the apparatuses and methods described herein should be understood to be inclusive, but all or a sub-set of the components and/or steps may alternatively be exclusive, and may be expressed as “consisting of’ or alternatively “consisting essentially of’ the various components, steps, sub-components or sub-steps. [0010] As used herein in the specification and claims, including as used in the examples and unless otherwise expressly specified, all numbers may be read as if prefaced by the word "about” or “approximately,” even if the term does not expressly appear.
  • a numeric value may have a value that is +/- 0.1% of the stated value (or range of values), +/- 1% of the stated value (or range of values), +/- 2% of the stated value (or range of values), +/- 5% of the stated value (or range of values), +/- 10% of the stated value (or range of values), etc.
  • Any numerical values given herein should also be understood to include about or approximately that value, unless the context indicates otherwise. For example, if the value " 10" is disclosed, then “about 10" is also disclosed.
  • any numerical range recited herein is intended to include all sub-ranges subsumed therein. It is also understood that when a value is disclosed that “less than or equal to” the value, “greater than or equal to the value” and possible ranges between values are also disclosed, as appropriately understood by the skilled artisan. For example, if the value "X” is disclosed the “less than or equal to X” as well as “greater than or equal to X” (e.g., where X is a numerical value) is also disclosed. It is also understood that throughout the application, data is provided in a number of different formats, and that this data, represents endpoints and starting points, and ranges for any combination of the data points.

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Abstract

L'invention concerne des appareils et des procédés pour déployer et/ou commander le mouvement d'éléments tubulaires flexibles tels que des endoscopes, à l'aide d'un ensemble liaison coulissante pour supporter l'élément tubulaire flexible. Par exemple, ces appareils peuvent comprendre une base, un ensemble de liaison relié à la base et comprenant : une pluralité de liaisons qui sont verticalement adjacentes l'une à l'autre, des paires adjacentes de liaisons étant chacune couplées de manière coulissante l'une à l'autre par des bandes flexibles opposées qui s'étendent autour d'une surface cylindrique d'une navette. Un entraînement linéaire peut entraîner l'extension et la rétraction des liaisons par mise en prise avec une seule navette de l'ensemble liaison.
PCT/US2024/049346 2023-09-28 2024-09-30 Robot télescopique Pending WO2025072977A1 (fr)

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WO2025072977A1 (fr) * 2023-09-28 2025-04-03 Neptune Medical Inc. Robot télescopique

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