ZA200403396B - High level constitutive production of anthrax protective antigen. - Google Patents

High level constitutive production of anthrax protective antigen. Download PDF

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Publication number
ZA200403396B
ZA200403396B ZA200403396A ZA200403396A ZA200403396B ZA 200403396 B ZA200403396 B ZA 200403396B ZA 200403396 A ZA200403396 A ZA 200403396A ZA 200403396 A ZA200403396 A ZA 200403396A ZA 200403396 B ZA200403396 B ZA 200403396B
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ZA
South Africa
Prior art keywords
cells
protective antigen
recombinant
coli
culture
Prior art date
Application number
ZA200403396A
Other languages
English (en)
Inventor
Bhatnagar Rakesh
Syed Mohsin Waheed
Vibha Chauhan
Original Assignee
Bhatnagar Rakesh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bhatnagar Rakesh filed Critical Bhatnagar Rakesh
Publication of ZA200403396B publication Critical patent/ZA200403396B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
  • Laminated Bodies (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
ZA200403396A 2001-11-05 2004-05-05 High level constitutive production of anthrax protective antigen. ZA200403396B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1127DE2001 IN190590B (de) 2001-11-05 2001-11-05

Publications (1)

Publication Number Publication Date
ZA200403396B true ZA200403396B (en) 2005-08-05

Family

ID=11097131

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200403396A ZA200403396B (en) 2001-11-05 2004-05-05 High level constitutive production of anthrax protective antigen.

Country Status (15)

Country Link
US (1) US7329513B2 (de)
EP (1) EP1442052B1 (de)
JP (1) JP2005510215A (de)
CN (1) CN100347189C (de)
AT (1) ATE484517T1 (de)
BR (1) BRPI0117173A2 (de)
CA (1) CA2465679A1 (de)
DE (1) DE60143276D1 (de)
IL (1) IL161725A0 (de)
IN (1) IN190590B (de)
MX (1) MXPA04004281A (de)
RU (1) RU2288272C2 (de)
UA (1) UA80809C2 (de)
WO (1) WO2003040179A1 (de)
ZA (1) ZA200403396B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80809C2 (en) * 2001-11-05 2007-11-12 Process for preparation of protective antigen protein of anthracis with e.coli
CA2526720C (en) 2003-05-22 2013-10-22 Fraunhofer Usa, Inc. Recombinant carrier molecule for expression, delivery and purification of target polypeptides
AU2003271835A1 (en) * 2003-06-06 2005-01-04 Avecia Limited Process for the separation of proteins
WO2005081749A2 (en) * 2004-01-23 2005-09-09 Avanir Pharmaceuticals, Inc. Neutralizing human antibodies to anthraxtoxin
US20060246079A1 (en) * 2003-11-14 2006-11-02 Morrow Phillip R Neutralizing human antibodies to anthrax toxin
US7355027B2 (en) 2004-06-16 2008-04-08 Dynport Vaccine Company Llc Bacillus anthracis protective antigen
US8101735B2 (en) 2004-06-16 2012-01-24 Health Protection Agency Preparation of protective antigen
CN100336908C (zh) * 2004-09-10 2007-09-12 中国人民解放军军事医学科学院微生物流行病研究所 一种制备重组炭疽保护性抗原的方法及其专用表达质粒
WO2007117264A2 (en) 2005-08-03 2007-10-18 Fraunhofer Usa, Inc. Compositions and methods for production of immunoglobulins
WO2008048344A2 (en) * 2006-02-13 2008-04-24 Fraunhofer Usa, Inc. Bacillus anthracis antigens, vaccine compositions, and related methods
AU2007215080A1 (en) 2006-02-13 2007-08-23 Fraunhofer Usa, Inc. Influenza antigens, vaccine compositions, and related methods
GB0607462D0 (en) * 2006-04-13 2006-05-24 Avecia Ltd Assay
US7794732B2 (en) * 2006-05-12 2010-09-14 Oklahoma Medical Research Foundation Anthrax compositions and methods of use and production
ATE527339T1 (de) 2006-06-30 2011-10-15 Univ Georgia Anthrax-kohlenhydrate sowie synthese und verwendungen davon
US8420607B2 (en) 2006-06-30 2013-04-16 University Of Georgia Research Foundation, Inc. Anthrax carbohydrates, synthesis and uses thereof
EP2178558B1 (de) 2007-07-11 2014-04-30 iBio, Inc. Yersinia pestis-antigene, impfstoffzusammensetzungen und zugehörige verfahren
WO2009126355A2 (en) * 2008-01-28 2009-10-15 Baxter International, Inc. Methods of increasing recombinant production of bacillus anthracis protective antigen
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
AU2009299615B2 (en) * 2008-10-02 2015-07-16 Pharmathene Inc. Anthrax vaccine formulation and uses thereof
US20100183675A1 (en) * 2009-01-22 2010-07-22 Allan Watkinson Stable vaccine compositions and methods of use
US8784819B2 (en) 2009-09-29 2014-07-22 Ibio Inc. Influenza hemagglutinin antibodies, compositions and related methods
US20120301951A1 (en) * 2010-11-18 2012-11-29 E. I. Du Pont De Nemours And Company Prevention of contamination of nutrient feed reservoirs & feed lines in bioreactor systems
RU2633504C1 (ru) * 2016-12-27 2017-10-12 Федеральное государственное учреждение "Федеральный исследовательский центр "Фундаментальные основы биотехнологии" Российской академии наук (ФИЦ Биотехнологии РАН) Штамм E.coli - продуцент полноразмерного протективного антигена Bacillus anthracis в форме вирусоподобных частиц
RU2633508C1 (ru) * 2016-12-27 2017-10-12 Федеральное государственное учреждение "Федеральный исследовательский центр "Фундаментальные основы биотехнологии" Российской академии наук (ФИЦ Биотехнологии РАН) Штамм E. coli - продуцент изолированного домена 1 протективного антигена Bacillus anthracis в форме вирусоподобных частиц
CN115125224B (zh) * 2022-08-11 2023-07-18 福州大学 一种可规模化生产具有活性的dna聚合酶的方法
CN117093572A (zh) * 2023-08-24 2023-11-21 中国建设银行股份有限公司 数据补录方法、装置、设备、存储介质及产品

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677274A (en) * 1993-02-12 1997-10-14 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services Anthrax toxin fusion proteins and related methods
US5591631A (en) * 1993-02-12 1997-01-07 The United States Of America As Represented By The Department Of Health And Human Services Anthrax toxin fusion proteins, nucleic acid encoding same
US5800821A (en) * 1995-03-10 1998-09-01 New England Medical Center Hospitals, Inc. Bacterial spores as a heat stable vaccine delivery system
GB9618107D0 (en) * 1996-08-30 1996-10-09 Secr Defence Vaccine production
AU3550599A (en) * 1998-04-07 1999-10-25 Wisconsin Alumni Research Foundation Enterotoxin-deficient bacillus
US20020086032A1 (en) * 1999-02-02 2002-07-04 Mahan Michael J. Producing antibodies with attenuated bacteria with altered DNA adenine methylase activity
WO2003055977A2 (en) * 2001-10-01 2003-07-10 Regents Of The University Of California A method for generating overexpression of alleles in genes of unknown function
UA80809C2 (en) * 2001-11-05 2007-11-12 Process for preparation of protective antigen protein of anthracis with e.coli
US7763451B2 (en) * 2001-11-09 2010-07-27 The United States Of America As Represented By The Department Of Health And Human Services Methods for preparing Bacillus anthracis protective antigen for use in vaccines

Also Published As

Publication number Publication date
EP1442052B1 (de) 2010-10-13
ATE484517T1 (de) 2010-10-15
WO2003040179A1 (en) 2003-05-15
RU2288272C2 (ru) 2006-11-27
CA2465679A1 (en) 2003-05-15
RU2004117085A (ru) 2005-03-27
BRPI0117173A2 (pt) 2018-04-17
EP1442052A1 (de) 2004-08-04
JP2005510215A (ja) 2005-04-21
IN190590B (de) 2003-08-09
CN1582298A (zh) 2005-02-16
UA80809C2 (en) 2007-11-12
CN100347189C (zh) 2007-11-07
DE60143276D1 (de) 2010-11-25
US7329513B2 (en) 2008-02-12
MXPA04004281A (es) 2005-03-31
US20050054038A1 (en) 2005-03-10
IL161725A0 (en) 2005-11-20
HK1072610A1 (zh) 2005-09-02

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