ZA200407940B - Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity - Google Patents

Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity Download PDF

Info

Publication number: ZA200407940B
Authority: ZA; South Africa
Prior art keywords: substituted; substituents; alkyl; unsubstituted; compound
Prior art date: 2002-04-29

Application number

ZA200407940A

Other languages

English (en)

Inventor

Richard Jiao

Lihu Yang

Sander G Mills

Changyou Zhou

Shankaran Kothandaraman

Cheng Tang

Gregori Morriello

Stephen D Goble

Alexander Pasternak

Gabor Butora

Deodialsingh Guiadeen

Christopher Moyes

Original Assignee

Merck & Co Inc

Merck Sharp & Dohme

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-29

Filing date

2004-10-01

Publication date

2006-06-28

2004-10-01 Application filed by Merck & Co Inc, Merck Sharp & Dohme filed Critical Merck & Co Inc

2006-06-28 Publication of ZA200407940B publication Critical patent/ZA200407940B/en

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA200407940A 2002-04-29 2004-10-01 Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity ZA200407940B (en)

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EP (1)	EP1501507B1 (fr)
JP (1)	JP3780291B2 (fr)
AT (1)	ATE396993T1 (fr)
AU (1)	AU2003231114B8 (fr)
CA (1)	CA2483752C (fr)
CY (1)	CY1110399T1 (fr)
DE (1)	DE60321333D1 (fr)
DK (1)	DK1501507T3 (fr)
ES (1)	ES2306867T3 (fr)
NZ (1)	NZ536477A (fr)
PT (1)	PT1501507E (fr)
SI (1)	SI1501507T1 (fr)
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2003
- 2003-04-25 EP EP03724241A patent/EP1501507B1/fr not_active Expired - Lifetime
- 2003-04-25 WO PCT/US2003/012929 patent/WO2003092586A2/fr not_active Ceased
- 2003-04-25 DE DE60321333T patent/DE60321333D1/de not_active Expired - Lifetime
- 2003-04-25 DK DK03724241T patent/DK1501507T3/da active
- 2003-04-25 JP JP2004500771A patent/JP3780291B2/ja not_active Expired - Fee Related
- 2003-04-25 SI SI200331285T patent/SI1501507T1/sl unknown
- 2003-04-25 NZ NZ536477A patent/NZ536477A/en not_active IP Right Cessation
- 2003-04-25 CA CA2483752A patent/CA2483752C/fr not_active Expired - Lifetime
- 2003-04-25 AU AU2003231114A patent/AU2003231114B8/en not_active Ceased
- 2003-04-25 PT PT03724241T patent/PT1501507E/pt unknown
- 2003-04-25 ES ES03724241T patent/ES2306867T3/es not_active Expired - Lifetime
- 2003-04-25 AT AT03724241T patent/ATE396993T1/de active
- 2003-04-29 US US10/425,167 patent/US6812234B2/en not_active Expired - Lifetime
2004
- 2004-10-01 ZA ZA200407940A patent/ZA200407940B/en unknown
2008
- 2008-08-26 CY CY20081100915T patent/CY1110399T1/el unknown

Also Published As

Publication number	Publication date
ES2306867T3 (es)	2008-11-16
DK1501507T3 (da)	2008-09-29
WO2003092586A3 (fr)	2004-09-16
DE60321333D1 (de)	2008-07-10
CA2483752A1 (fr)	2003-11-13
CY1110399T1 (el)	2014-04-09
WO2003092586A2 (fr)	2003-11-13
PT1501507E (pt)	2008-08-12
SI1501507T1 (sl)	2008-12-31
JP3780291B2 (ja)	2006-05-31
AU2003231114B2 (en)	2008-07-24
AU2003231114B8 (en)	2008-08-14
EP1501507B1 (fr)	2008-05-28
JP2005523929A (ja)	2005-08-11
ATE396993T1 (de)	2008-06-15
US20040167156A1 (en)	2004-08-26
EP1501507A2 (fr)	2005-02-02
US6812234B2 (en)	2004-11-02
AU2003231114A1 (en)	2003-11-17
NZ536477A (en)	2005-05-27
EP1501507A4 (fr)	2006-05-17
CA2483752C (fr)	2011-03-29

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US7786305B2 (en)	2010-08-31	Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
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AU2005208887B2 (en)	2010-02-25	Aminocyclopentyl pyridopyrazinone modulators of chemokine receptor activity
US20060178363A1 (en)	2006-08-10	Tetrahydropyranyl cyclopentyl heterocyclic amide modulators of chemokine receptor activity
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US7230008B2 (en)	2007-06-12	Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
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US7589085B2 (en)	2009-09-15	Tetrahydropyran heterocyclic cyclopentyl heteroaryl modulators of chemokine receptor activity
US20070299104A1 (en)	2007-12-27	Tetrahydropyranyl Cyclopentyl 1-Substituted and 1,1-Disubstituted Tetrahydroisoquinoline Modulators of Chemokine Receptor Activity