ZA847967B - Diarylindane-1,3-diones,their preparation and use - Google Patents

Diarylindane-1,3-diones,their preparation and use

Info

Publication number
ZA847967B
ZA847967B ZA847967A ZA847967A ZA847967B ZA 847967 B ZA847967 B ZA 847967B ZA 847967 A ZA847967 A ZA 847967A ZA 847967 A ZA847967 A ZA 847967A ZA 847967 B ZA847967 B ZA 847967B
Authority
ZA
South Africa
Prior art keywords
diones
diarylindane
preparation
arylindane
inflammatories
Prior art date
Application number
ZA847967A
Other languages
English (en)
Inventor
Alexander Cupples Campbell
Donald Fraser Melven Stevenson
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA847967B publication Critical patent/ZA847967B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
    • C07C49/67—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/39—Unsaturated compounds containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Pens And Brushes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
ZA847967A 1983-10-14 1984-10-11 Diarylindane-1,3-diones,their preparation and use ZA847967B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838327598A GB8327598D0 (en) 1983-10-14 1983-10-14 Pharmacologically active diarylindane-13-diones

Publications (1)

Publication Number Publication Date
ZA847967B true ZA847967B (en) 1985-05-29

Family

ID=10550228

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA847967A ZA847967B (en) 1983-10-14 1984-10-11 Diarylindane-1,3-diones,their preparation and use

Country Status (16)

Country Link
US (1) US4569945A (da)
EP (1) EP0138272B1 (da)
JP (1) JPS60109541A (da)
KR (1) KR920003101B1 (da)
AT (1) ATE32214T1 (da)
AU (1) AU561309B2 (da)
CA (1) CA1245232A (da)
DE (1) DE3469020D1 (da)
DK (1) DK491984A (da)
ES (1) ES536743A0 (da)
FI (1) FI82923C (da)
GB (1) GB8327598D0 (da)
GR (1) GR80629B (da)
HU (1) HUT35627A (da)
PT (1) PT79356B (da)
ZA (1) ZA847967B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2556966B1 (fr) * 1983-12-26 1987-09-25 Bouchard Sa Laboratoires Nouvelle application therapeutique d'un derive de l'indane dione et les compositions pharmaceutiques destinees a cet usage
FR2593501B1 (fr) * 1986-01-29 1988-05-06 Panmedica Sa Nouveaux derives bis (r-oxyimino)-5,7 dihydro-6,7 (5h) dibenzo (a,c) cycloheptene, leurs procedes de preparation et leur application comme medicaments
JP2582898B2 (ja) * 1989-05-16 1997-02-19 三菱化学株式会社 インダン―１，３―ジオン誘導体およびこれを有効成分とする除草剤
PT2722322T (pt) 2011-06-16 2019-09-27 Univ Leuven Kath Derivado de 1,3-di-oxo-indeno, seu sal farmaceuticamente aceitável ou isómero ótico, seu método de preparação, e composição farmacêutica contendo o mesmo como ingrediente ativo, antiviral
WO2014092514A1 (ko) 2012-12-14 2014-06-19 한국화학연구원 신규한 화합물, 이의 약학적으로 허용가능한 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 또는 치료용 약학적 조성물
KR20260004471A (ko) 2020-04-20 2026-01-08 노파르티스 아게 항바이러스 1,3-다이-옥소-인덴 화합물
TWI909320B (zh) 2020-04-20 2025-12-21 瑞士商諾華公司 抗病毒性1,3-二氧代茚化合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2361517A (en) * 1939-09-22 1944-10-31 Gen Electric Sealing apparatus
DE947473C (de) * 1953-04-30 1956-08-16 Geigy Ag J R Verfahren zur Herstellung von 2-(p-Chlorphenyl)-indan-1, 3-dion
DE1130439B (de) * 1960-06-27 1962-05-30 Us Vitamin Pharm Corp Verfahren zur Herstellung von 2-Arylindandionen
BE668871A (da) * 1964-08-27
GB1172696A (en) * 1966-10-20 1969-12-03 Koninklijke Pharma Fab Nv Phenyl-Indandione Derivatives
US3784606A (en) * 1968-08-29 1974-01-08 Pfizer Novel 2-aryl-1,3-indandiones and 2-aryl-2,3-dihydrobenz(f)indene-1,3-diones
US3879468A (en) * 1969-04-14 1975-04-22 Union Carbide Corp 2-(poly substituted phenyl)-1,3-indandione compounds
US3803240A (en) * 1969-04-14 1974-04-09 Union Carbide Corp 2-(2,6-substituted-phenyl)-1,3-indandiones
US3784605A (en) * 1971-05-13 1974-01-08 Union Carbide Corp 2-(polysubstituted phenyl)-1,3-indandione compounds
GB1380089A (en) * 1972-01-20 1975-01-08 Istituto Gentilipisa Spa 2-aryl-1,3-indandiones
US3978231A (en) * 1972-01-25 1976-08-31 Beecham Group Limited Pharmaceutical compositions and method of treating allergic conditions utilizing 2-nitroindane-1,3-dione derivatives as the active agents
US3976681A (en) * 1973-10-12 1976-08-24 Merck & Co., Inc. [1,3-Dioxo-2-substituted and 2,2-disubstituted- indanyloxy (or thio] alkanoic acids
FR2392951A2 (fr) * 1975-02-07 1978-12-29 Creat Lab Nouveaux derives de la ninhydrine, leurs procedes de preparation et medicaments contenant ces derives

Also Published As

Publication number Publication date
AU561309B2 (en) 1987-05-07
GR80629B (en) 1985-02-12
AU3418484A (en) 1985-04-18
PT79356B (en) 1986-09-08
EP0138272A1 (en) 1985-04-24
EP0138272B1 (en) 1988-01-27
CA1245232A (en) 1988-11-22
DK491984A (da) 1985-04-15
FI844020L (fi) 1985-04-15
KR850003382A (ko) 1985-06-17
JPS60109541A (ja) 1985-06-15
KR920003101B1 (ko) 1992-04-18
DK491984D0 (da) 1984-10-12
DE3469020D1 (en) 1988-03-03
ES8602582A1 (es) 1985-11-16
ATE32214T1 (de) 1988-02-15
FI844020A0 (fi) 1984-10-12
US4569945A (en) 1986-02-11
HUT35627A (en) 1985-07-29
FI82923C (fi) 1991-05-10
FI82923B (fi) 1991-01-31
PT79356A (en) 1984-11-01
GB8327598D0 (en) 1983-11-16
ES536743A0 (es) 1985-11-16

Similar Documents

Publication Publication Date Title
DE3379589D1 (en) Enzyme composition for cleaning, the use thereof and preparation of the composition
GB2070429B (en) Use of perfluorocarbon as burn treatment
DE3579113D1 (de) Zusammensetzungen zur milderung, behandlung und bestimmungung von arthritschen krankheiten und aehnlichen zustaenden.
IT1209254B (it) Procedimento per rilevare perdite in condutture e apparecchiature per l'attuazione del procedimento.
IT1151433B (it) Ugella per l'insufflamento di gas,produzione ed impiego dello stesso
MW3080A1 (en) Preparations for the treatment of theileriosis and their use
AU91400S (en) Tyre
ES8800160A1 (es) Procedimiento de obtencion de acidos quinolincarboxilicos con propiedades antibacteriales.
HK8580A (en) New form of flunisolide and the use of flunisolide to treat respiratory diseases
IL57596A0 (en) Process the purification and concentration of urokinase
DE3469020D1 (en) Diarylindane-1,3-diones, their preparation and use
JPS5516082A (en) Manufacture of polyynnvinylpyrrolidonee2 denatured polymer and its use
ZA855224B (en) Pyrrol-1-ylphenyldihydropyridazinones,their preparation and their use
AU91399S (en) Tyre
ZA815346B (en) New medicament belonging to the family of glycosylglucans and its application in gastro-enterology,particularly in the treatment of disorders of the colon
DE2960021D1 (en) Acyloxy-2-butenes, their preparation and their use for the preparation of 4-acetoxytiglinaldehyde
IT1173473B (it) Procedimento per la preparazione di 1,8-diidrossi-10-acil-9-antroni,in particolare per l'uso nel trattamento di psoriasi
EP0270782A3 (en) Therapeutic agents for the prophylaxis of tumour metastasis
IT8421820A0 (it) Preparazione del 3,3,3-trifluoro-2-trifluorometilpro pene.
IL72467A0 (en) New 1,2-diaryl-3-azolylpropane derivatives,their preparation and their use as agents for the treatment of plants
DE2961463D1 (en) Monoazo compounds of the acetoacetylaminobenzene series, their preparation and their use
JPS5626879A (en) Imidazolyllenol ether* its manufacture and use as bactericide
IL57838A0 (en) N-cyclohexyl-n-methoxyacetamide,its preparation and its use in the preparation of o-methyl-n-cyclohexyl-2,5-dimethylfuran-3-hydroxamic acid
IT8520282A0 (it) Procedimento per migliorare le proprieta' del cemento, e cemento cosi' ottenuto.
ZA795491B (en) Treatment of influenza with 2-ester-substituted-3,4-dihydro-3-oxoquinoxalines