ZA956327B - Novel pyrrolocarbazoles - Google Patents

Novel pyrrolocarbazoles

Info

Publication number: ZA956327B
Authority: ZA; South Africa
Prior art keywords: pyrrolocarbazoles; novel; lower alkyl; hydrogen; heteroaryl
Prior art date: 1994-08-04

Application number

ZA956327A

Other languages

English (en)

Inventor

Chris Allen Broka

Original Assignee

Hoffman La Roche A G F

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-04

Filing date

1995-07-28

Publication date

1996-02-04

1995-07-28 Application filed by Hoffman La Roche A G F filed Critical Hoffman La Roche A G F

1996-02-04 Publication of ZA956327B publication Critical patent/ZA956327B/xx

Links

QNMMYUBZGLXCCK-UHFFFAOYSA-N pyrrolo[3,2-a]carbazole Chemical class N1=C2C=CC=CC2=C2C1=C1C=CN=C1C=C2 QNMMYUBZGLXCCK-UHFFFAOYSA-N 0.000 title 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
239000002246 antineoplastic agent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229940127089 cytotoxic agent Drugs 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA956327A 1994-08-04 1995-07-28 Novel pyrrolocarbazoles ZA956327B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28604394A	1994-08-04	1994-08-04

Publications (1)

Publication Number	Publication Date
ZA956327B true ZA956327B (en)	1996-02-04

Family

ID=23096813

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA956327A ZA956327B (en)	1994-08-04	1995-07-28	Novel pyrrolocarbazoles

Country Status (29)

Country	Link
US (1)	US5721267A (fr)
EP (1)	EP0695755B1 (fr)
JP (1)	JP2672290B2 (fr)
KR (1)	KR100326790B1 (fr)
CN (1)	CN1051551C (fr)
AT (1)	ATE172463T1 (fr)
AU (1)	AU692563B2 (fr)
BR (1)	BR9503536A (fr)
CA (1)	CA2155148A1 (fr)
CO (1)	CO4410329A1 (fr)
CZ (1)	CZ288583B6 (fr)
DE (1)	DE69505470T2 (fr)
DK (1)	DK0695755T3 (fr)
ES (1)	ES2123873T3 (fr)
FI (1)	FI111258B (fr)
HU (1)	HU225567B1 (fr)
IL (1)	IL114785A (fr)
MA (1)	MA23639A1 (fr)
MY (1)	MY117092A (fr)
NO (1)	NO304833B1 (fr)
NZ (1)	NZ272687A (fr)
PE (1)	PE34996A1 (fr)
PL (1)	PL180801B1 (fr)
RU (1)	RU2162089C2 (fr)
SA (1)	SA95160203B1 (fr)
TR (1)	TR199500954A1 (fr)
TW (1)	TW403652B (fr)
UY (1)	UY24010A1 (fr)
ZA (1)	ZA956327B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1283203B1 (it) *	1996-03-07	1998-04-16	Ausimont Spa	Composizioni estinguenti la fiamma
US6020298A (en) *	1997-03-05	2000-02-01	Ausimont S.P.A.	Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) *	1997-10-07	2004-04-15	Zentaris Gmbh	Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en)	2000-05-09	2006-10-17	Cephalon, Inc.	Multicyclic compounds and the use thereof
US20050070591A1 (en) *	2001-12-18	2005-03-31	Fumihiko Kanai	Indole derivative
US7094798B1 (en)	2002-04-26	2006-08-22	Pfizer Inc	Inhibitors of checkpoint kinases (Wee1 and Chk1)
EP1501831A1 (fr) *	2002-04-26	2005-02-02	Warner-Lambert Company Llc	Inhibiteurs de checkpoint kinases (wee1 et chk1)
JP2012051804A (ja) *	2008-12-26	2012-03-15	Kyoto Univ	Ｅｇ５阻害剤
RU2404983C1 (ru) *	2009-06-08	2010-11-27	Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Южный Федеральный Университет"	СПОСОБ ПОЛУЧЕНИЯ 2-R1-6-R2-5-АРИЛ-ПИРРОЛО[3,4-с]КАРБАЗОЛ-1,3(2Н,6Н)-ДИОНОВ
EP3613729A1 (fr) *	2009-06-10	2020-02-26	Chugai Seiyaku Kabushiki Kaisha	Composés tétracycliques
CA2808210C (fr)	2010-08-20	2019-10-01	Chugai Seiyaku Kabushiki Kaisha	Composes tetracycliques presentant une activite d'inhibition d'alk et compositions associees
SI2902029T1 (sl)	2012-09-25	2018-11-30	Chugai Seiyaku Kabushiki Kaisha	Inhibitor ret
KR101577098B1 (ko)	2012-11-20	2015-12-14	주식회사 두산	유기 화합물 및 이를 포함하는 유기 전계 발광 소자
WO2015163447A1 (fr)	2014-04-25	2015-10-29	中外製薬株式会社	Nouveau cristal de composé tétracyclique
WO2015163448A1 (fr)	2014-04-25	2015-10-29	中外製薬株式会社	Préparation contenant un composé tétracyclique à haute dose
TWI831347B (zh)	2014-08-08	2024-02-01	日商中外製藥股份有限公司	包含４環性化合物的非晶質體之固體分散體及製劑
CA2973857C (fr)	2015-01-16	2023-11-07	Chugai Seiyaku Kabushiki Kaisha	Medicament d'association
EP4316598B1 (fr)	2018-06-29	2025-06-18	Chugai Seiyaku Kabushiki Kaisha	Composition pharmaceutique contenant un médicament basique peu soluble
BR112021001145A2 (pt)	2018-09-04	2021-04-20	Chugai Seiyaku Kabushiki Kaisha	método para a produção de composto tetracíclico
KR102509614B1 (ko) *	2022-08-09	2023-03-13	김학수	부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8611762D0 (en) *	1986-05-14	1986-06-25	Wellcome Found	Polycyclic biocidal compounds
US4785085A (en) *	1986-11-21	1988-11-15	Bristol-Myers Company	Rebeccamycin analogs
CZ280738B6 (cs) *	1988-02-10	1996-04-17	F. Hoffmann - La Roche And Co., Aktiengesellschaft	Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
DE3833008A1 (de) *	1988-09-29	1990-04-05	Goedecke Ag	Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) *	1989-02-23	1991-02-15	Hoffmann La Roche	Pyrroles substitues
US5166204A (en) *	1989-11-01	1992-11-24	Toyama Chemical Co., Ltd.	Isoindole derivatives and salts thereof and antitumor agent comprising the same
DE4005969A1 (de) *	1990-02-26	1991-08-29	Boehringer Mannheim Gmbh	Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) *	1992-05-30	1993-12-02	Goedecke Ag	Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) *	1993-05-10	1997-05-29	F. Hoffmann-La Roche Ag	Substituted pyrroles
DE69409641T2 (de) *	1993-05-28	1998-11-26	Cephalon, Inc., West Chester, Pa.	Anwendung von indolocarbazol-derivaten zur behandlung von prostataerkrankungen

1995
- 1995-07-21 DK DK95111472T patent/DK0695755T3/da active
- 1995-07-21 ES ES95111472T patent/ES2123873T3/es not_active Expired - Lifetime
- 1995-07-21 DE DE69505470T patent/DE69505470T2/de not_active Expired - Fee Related
- 1995-07-21 EP EP95111472A patent/EP0695755B1/fr not_active Expired - Lifetime
- 1995-07-21 AT AT95111472T patent/ATE172463T1/de not_active IP Right Cessation
- 1995-07-25 TW TW084107708A patent/TW403652B/zh not_active IP Right Cessation
- 1995-07-27 AU AU27220/95A patent/AU692563B2/en not_active Ceased
- 1995-07-28 ZA ZA956327A patent/ZA956327B/xx unknown
- 1995-07-31 HU HU9502270A patent/HU225567B1/hu not_active IP Right Cessation
- 1995-07-31 NZ NZ272687A patent/NZ272687A/en unknown
- 1995-07-31 IL IL114785A patent/IL114785A/en not_active IP Right Cessation
- 1995-08-01 CA CA002155148A patent/CA2155148A1/fr not_active Abandoned
- 1995-08-01 PE PE1995275075A patent/PE34996A1/es not_active Application Discontinuation
- 1995-08-02 MY MYPI95002255A patent/MY117092A/en unknown
- 1995-08-03 FI FI953710A patent/FI111258B/fi not_active IP Right Cessation
- 1995-08-03 BR BR9503536A patent/BR9503536A/pt not_active IP Right Cessation
- 1995-08-03 CZ CZ19951997A patent/CZ288583B6/cs not_active IP Right Cessation
- 1995-08-03 CO CO95034716A patent/CO4410329A1/es unknown
- 1995-08-03 RU RU95113107/04A patent/RU2162089C2/ru not_active IP Right Cessation
- 1995-08-03 KR KR1019950023928A patent/KR100326790B1/ko not_active Expired - Fee Related
- 1995-08-03 NO NO953052A patent/NO304833B1/no unknown
- 1995-08-03 MA MA23980A patent/MA23639A1/fr unknown
- 1995-08-03 UY UY24010A patent/UY24010A1/es not_active IP Right Cessation
- 1995-08-03 CN CN95108687A patent/CN1051551C/zh not_active Expired - Fee Related
- 1995-08-03 TR TR95/00954A patent/TR199500954A1/xx unknown
- 1995-08-03 JP JP7197846A patent/JP2672290B2/ja not_active Expired - Fee Related
- 1995-08-03 PL PL95309874A patent/PL180801B1/pl not_active IP Right Cessation
- 1995-08-27 SA SA95160203A patent/SA95160203B1/ar unknown
1997
- 1997-01-22 US US08/787,594 patent/US5721267A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HU9502270D0 (en)	1995-09-28
AU692563B2 (en)	1998-06-11
KR100326790B1 (ko)	2002-07-27
NZ272687A (en)	1997-04-24
EP0695755B1 (fr)	1998-10-21
PE34996A1 (es)	1996-10-01
CO4410329A1 (es)	1997-01-09
FI111258B (fi)	2003-06-30
NO953052D0 (no)	1995-08-03
CA2155148A1 (fr)	1996-02-05
HUT73437A (en)	1996-07-29
RU2162089C2 (ru)	2001-01-20
PL309874A1 (en)	1996-02-05
CN1123280A (zh)	1996-05-29
DE69505470D1 (de)	1998-11-26
MA23639A1 (fr)	1996-04-01
NO953052L (no)	1996-02-05
EP0695755A1 (fr)	1996-02-07
CN1051551C (zh)	2000-04-19
ES2123873T3 (es)	1999-01-16
FI953710A0 (fi)	1995-08-03
TR199500954A1 (tr)	1996-10-21
IL114785A0 (en)	1995-11-27
AU2722095A (en)	1996-02-15
DK0695755T3 (da)	1999-06-28
UY24010A1 (es)	2000-12-29
IL114785A (en)	1998-06-15
KR960007592A (ko)	1996-03-22
ATE172463T1 (de)	1998-11-15
DE69505470T2 (de)	1999-05-12
NO304833B1 (no)	1999-02-22
HK1012341A1 (en)	1999-07-30
JPH0859666A (ja)	1996-03-05
TW403652B (en)	2000-09-01
US5721267A (en)	1998-02-24
BR9503536A (pt)	1996-06-04
FI953710L (fi)	1996-02-05
CZ288583B6 (cs)	2001-07-11
CZ199795A3 (en)	1996-02-14
SA95160203B1 (ar)	2005-07-31
PL180801B1 (pl)	2001-04-30
HU225567B1 (en)	2007-03-28
MY117092A (en)	2004-05-31
JP2672290B2 (ja)	1997-11-05

Publication	Publication Date	Title
HUT73437A (en)	1996-07-29	Novel pyrrolocarbazoles
IL101012A0 (en)	1992-11-15	Pyranyl cyanoguanadine derivatives,processes for the preparation thereof and cardioplegic solution containing the same
TW290546B (fr)	1996-11-11
AU4497293A (en)	1994-07-14	Phenoxy- and phenoxyalkyl-piperidines as antiviral agents
AU9281198A (en)	1999-04-23	Benzofuran derivatives
AU591640B2 (en)	1989-12-14	Quinolonecarboxylic acid derivatives
IE851205L (en)	1985-11-15	Beta-carbolines
EP0641770A4 (fr)	1995-06-28	Nouveau compose a activite inhibitrice de l'agregation des plaquettes.
DK1031556T3 (da)	2003-02-24	2-phenoxyanilinderivater
EP0566175A3 (fr)	1994-01-19
EP0601191A4 (en)	1994-08-17	Novel tetracyclic compound.
EP0555479A4 (fr)	1994-02-09
AU630839B2 (en)	1992-11-05	Sulfinyl imidazole derivatives and antiulcer agents containing the same
ATE105565T1 (de)	1994-05-15	Pradimicinderivate.
FI883507A0 (fi)	1988-07-26	Naftotiazepinderivat och deras framstaellning.
TW288012B (fr)	1996-10-11
GR3015002T3 (en)	1995-05-31	1,4-Dihydro-4-oxo-3-quinolone derivatives as selectively toxic mammalian antibacterial agents.
EP0573659A4 (en)	1994-09-07	Pyrazolothiazolopyrimidine derivative
TW275629B (fr)	1996-05-11
AU4370489A (en)	1990-05-03	The use of oxidized polyamines, especially nn'-bis-(3- propionaldehyde)-1-4-diaminobutane (sperminedialdehyde) as immunosuppressive agents
EP0443474A3 (en)	1992-04-22	1-phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents