ZA985918B - Process for the production of indole derivatives. - Google Patents
Process for the production of indole derivatives.Info
- Publication number
- ZA985918B ZA985918B ZA9805918A ZA985918A ZA985918B ZA 985918 B ZA985918 B ZA 985918B ZA 9805918 A ZA9805918 A ZA 9805918A ZA 985918 A ZA985918 A ZA 985918A ZA 985918 B ZA985918 B ZA 985918B
- Authority
- ZA
- South Africa
- Prior art keywords
- production
- indole derivatives
- indole
- derivatives
- Prior art date
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9714383.8A GB9714383D0 (en) | 1997-07-08 | 1997-07-08 | Improved process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA985918B true ZA985918B (en) | 2000-01-10 |
Family
ID=10815557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9805918A ZA985918B (en) | 1997-07-08 | 1998-07-06 | Process for the production of indole derivatives. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6281357B1 (de) |
| EP (1) | EP0975594B1 (de) |
| AR (1) | AR013183A1 (de) |
| AT (1) | ATE224367T1 (de) |
| AU (1) | AU8339798A (de) |
| CA (1) | CA2286720A1 (de) |
| DE (1) | DE69808068T2 (de) |
| DK (1) | DK0975594T3 (de) |
| ES (1) | ES2182342T3 (de) |
| GB (1) | GB9714383D0 (de) |
| IL (1) | IL132442A0 (de) |
| PL (1) | PL337000A1 (de) |
| PT (1) | PT975594E (de) |
| WO (1) | WO1999002493A1 (de) |
| ZA (1) | ZA985918B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9801690D0 (en) * | 1998-01-27 | 1998-03-25 | Pfizer Ltd | Therapeutic agents |
| US6100291A (en) * | 1998-03-16 | 2000-08-08 | Allelix Biopharmaceuticals Inc. | Pyrrolidine-indole compounds having 5-HT6 affinity |
| EP1572647B1 (de) | 2002-12-20 | 2016-09-21 | Basf Se | Herstellung von aminen und deren zwischenverbindungen |
| US20100022581A1 (en) * | 2008-07-02 | 2010-01-28 | Memory Pharmaceuticals Corporation | Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity |
| CN102775342A (zh) * | 2011-05-12 | 2012-11-14 | 上海医药工业研究院 | 一种抗偏头痛药物阿莫曲坦的制备方法 |
| ES2747768T3 (es) | 2017-03-20 | 2020-03-11 | Forma Therapeutics Inc | Composiciones de pirrolopirrol como activadores de quinasa de piruvato (PKR) |
| ES2989438T3 (es) | 2018-09-19 | 2024-11-26 | Novo Nordisk Healthcare Ag | Activación de la piruvato cinasa R |
| US12053458B2 (en) | 2018-09-19 | 2024-08-06 | Novo Nordisk Health Care Ag | Treating sickle cell disease with a pyruvate kinase R activating compound |
| CN110483341A (zh) * | 2019-07-23 | 2019-11-22 | 上海药明康德新药开发有限公司 | 一种1-氰基-n-甲基甲磺酰胺的合成方法 |
| US20220378756A1 (en) | 2019-09-19 | 2022-12-01 | Forma Therapeutics, Inc. | Activating pyruvate kinase r |
| US12128035B2 (en) | 2021-03-19 | 2024-10-29 | Novo Nordisk Health Care Ag | Activating pyruvate kinase R |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| PL170330B1 (pl) * | 1990-10-15 | 1996-11-29 | Pfizer | Sposób wytwarzania nowych pochodnych indolu PL PL PL PL PL PL |
| GB9103770D0 (en) * | 1991-02-22 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| CA2084531A1 (en) * | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
-
1997
- 1997-07-08 GB GBGB9714383.8A patent/GB9714383D0/en active Pending
-
1998
- 1998-06-16 WO PCT/EP1998/003996 patent/WO1999002493A1/en not_active Ceased
- 1998-06-16 PT PT98933651T patent/PT975594E/pt unknown
- 1998-06-16 EP EP98933651A patent/EP0975594B1/de not_active Expired - Lifetime
- 1998-06-16 AU AU83397/98A patent/AU8339798A/en not_active Abandoned
- 1998-06-16 IL IL13244298A patent/IL132442A0/xx unknown
- 1998-06-16 US US09/381,072 patent/US6281357B1/en not_active Expired - Fee Related
- 1998-06-16 DK DK98933651T patent/DK0975594T3/da active
- 1998-06-16 ES ES98933651T patent/ES2182342T3/es not_active Expired - Lifetime
- 1998-06-16 DE DE69808068T patent/DE69808068T2/de not_active Expired - Fee Related
- 1998-06-16 AT AT98933651T patent/ATE224367T1/de not_active IP Right Cessation
- 1998-06-16 PL PL98337000A patent/PL337000A1/xx unknown
- 1998-06-16 CA CA002286720A patent/CA2286720A1/en not_active Abandoned
- 1998-07-06 ZA ZA9805918A patent/ZA985918B/xx unknown
- 1998-07-06 AR ARP980103279A patent/AR013183A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0975594A1 (de) | 2000-02-02 |
| WO1999002493A1 (en) | 1999-01-21 |
| PL337000A1 (en) | 2000-07-31 |
| US6281357B1 (en) | 2001-08-28 |
| ATE224367T1 (de) | 2002-10-15 |
| AU8339798A (en) | 1999-02-08 |
| AR013183A1 (es) | 2000-12-13 |
| DK0975594T3 (da) | 2002-10-14 |
| DE69808068D1 (de) | 2002-10-24 |
| EP0975594B1 (de) | 2002-09-18 |
| ES2182342T3 (es) | 2003-03-01 |
| GB9714383D0 (en) | 1997-09-10 |
| CA2286720A1 (en) | 1999-01-21 |
| IL132442A0 (en) | 2001-03-19 |
| PT975594E (pt) | 2002-12-31 |
| DE69808068T2 (de) | 2003-02-06 |
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