AP1704A - Water-soluble powdery or granular compositions based on phenanthridines and their uses. - Google Patents

Water-soluble powdery or granular compositions based on phenanthridines and their uses.

Info

Publication number
AP1704A
AP1704A APAP/P/2003/002817A AP2003002817A AP1704A AP 1704 A AP1704 A AP 1704A AP 2003002817 A AP2003002817 A AP 2003002817A AP 1704 A AP1704 A AP 1704A
Authority
AP
ARIPO
Prior art keywords
water
phenanthridines
soluble
compositions based
granular compositions
Prior art date
Application number
APAP/P/2003/002817A
Other versions
AP2003002817A0 (en
Inventor
Guy Derrieu
Original Assignee
Virbac Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virbac Sa filed Critical Virbac Sa
Publication of AP2003002817A0 publication Critical patent/AP2003002817A0/en
Application granted granted Critical
Publication of AP1704A publication Critical patent/AP1704A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to compositions which are present in the form of powders or granules which are soluble in small quantities of water and which are intended to permit the complete and rapid dissolution of active compounds, in particular phenanthridines, and to their uses. These compositions comprise, in combination and in pulverulent or granulated form, from 5.0 to 50% w/w of at least one phenanthridine, or one of its pharmaceutically acceptable salts, and from 50 to 95% w/w of at least one water-soluble co-solvent. Uses: prevention and treatment of trypanosomiases in animals, either on their own or as co-infections with other parasites.
APAP/P/2003/002817A 2001-01-08 2002-01-03 Water-soluble powdery or granular compositions based on phenanthridines and their uses. AP1704A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0100170A FR2819188B1 (en) 2001-01-08 2001-01-08 WATER-SOLUBLE PULVERULENT OR GRANULATED COMPOSITIONS BASED ON PHENANTHRIDINES AND USES THEREOF
PCT/FR2002/000008 WO2002053132A1 (en) 2001-01-08 2002-01-03 Water-soluble powdery or granular compositions based on phenanthridines and their uses

Publications (2)

Publication Number Publication Date
AP2003002817A0 AP2003002817A0 (en) 2003-06-30
AP1704A true AP1704A (en) 2007-01-02

Family

ID=8858580

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/2003/002817A AP1704A (en) 2001-01-08 2002-01-03 Water-soluble powdery or granular compositions based on phenanthridines and their uses.

Country Status (4)

Country Link
AP (1) AP1704A (en)
FR (1) FR2819188B1 (en)
OA (1) OA12437A (en)
WO (1) WO2002053132A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2416004B1 (en) * 2012-01-24 2014-01-28 Investigaciones Farmaceuticas Y Veterinarias, S.L. PHARMACEUTICAL COMPOSITION THAT INCLUDES ISOMETAMIDIUM CHLORIDE IN SOLUTION FOR THE TREATMENT OF TRIPANOSOMIASIS IN ANIMALS.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB904797A (en) * 1959-12-23 1962-08-29 Boots Pure Drug Co Ltd Ophthalmic medicaments comprising phenanthridinium salts
EP0193414A2 (en) * 1985-03-01 1986-09-03 David John Fluck Liposomes, process for their preparation and compositions containing them

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB904797A (en) * 1959-12-23 1962-08-29 Boots Pure Drug Co Ltd Ophthalmic medicaments comprising phenanthridinium salts
EP0193414A2 (en) * 1985-03-01 1986-09-03 David John Fluck Liposomes, process for their preparation and compositions containing them

Also Published As

Publication number Publication date
OA12437A (en) 2006-05-22
FR2819188B1 (en) 2003-03-14
WO2002053132A1 (en) 2002-07-11
AP2003002817A0 (en) 2003-06-30
FR2819188A1 (en) 2002-07-12

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