AP2000001971A0 - Homogeneous pharmaceutical compositions comprising abacavir, lamivudine and zidovudine. - Google Patents
Homogeneous pharmaceutical compositions comprising abacavir, lamivudine and zidovudine.Info
- Publication number
- AP2000001971A0 AP2000001971A0 APAP/P/2000/001971A AP2000001971A AP2000001971A0 AP 2000001971 A0 AP2000001971 A0 AP 2000001971A0 AP 2000001971 A AP2000001971 A AP 2000001971A AP 2000001971 A0 AP2000001971 A0 AP 2000001971A0
- Authority
- AP
- ARIPO
- Prior art keywords
- abacavir
- lamivudine
- zidovudine
- pharmaceutical compositions
- homogeneous pharmaceutical
- Prior art date
Links
- 229960004748 abacavir Drugs 0.000 title abstract 2
- MCGSCOLBFJQGHM-SCZZXKLOSA-N abacavir Chemical compound C=12N=CN([C@H]3C=C[C@@H](CO)C3)C2=NC(N)=NC=1NC1CC1 MCGSCOLBFJQGHM-SCZZXKLOSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- LHCOVOKZWQYODM-CPEOKENHSA-N 4-amino-1-[(2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2r,4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1.O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 LHCOVOKZWQYODM-CPEOKENHSA-N 0.000 title 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229960001627 lamivudine Drugs 0.000 abstract 1
- JTEGQNOMFQHVDC-NKWVEPMBSA-N lamivudine Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1 JTEGQNOMFQHVDC-NKWVEPMBSA-N 0.000 abstract 1
- 229960002555 zidovudine Drugs 0.000 abstract 1
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9809213.3A GB9809213D0 (en) | 1998-04-29 | 1998-04-29 | Pharmaceutical compositions |
| PCT/EP1999/002794 WO1999055372A1 (en) | 1998-04-29 | 1999-04-26 | Homogeneous pharmaceutical compositions comprising abacavir, lamivudine and zidovudine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AP2000001971A0 true AP2000001971A0 (en) | 2000-12-31 |
Family
ID=10831228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/2000/001971A AP2000001971A0 (en) | 1998-04-29 | 1999-04-26 | Homogeneous pharmaceutical compositions comprising abacavir, lamivudine and zidovudine. |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1083932A1 (no) |
| JP (1) | JP2002512979A (no) |
| KR (1) | KR20010043128A (no) |
| CN (1) | CN1411380A (no) |
| AP (1) | AP2000001971A0 (no) |
| AU (1) | AU4135599A (no) |
| BR (1) | BR9910071A (no) |
| CA (1) | CA2330391A1 (no) |
| EA (1) | EA200000997A1 (no) |
| EE (1) | EE200000646A (no) |
| GB (1) | GB9809213D0 (no) |
| HR (1) | HRP20000732A2 (no) |
| HU (1) | HUP0101622A3 (no) |
| ID (1) | ID26955A (no) |
| IL (1) | IL139181A0 (no) |
| IS (1) | IS5675A (no) |
| NO (1) | NO20005418L (no) |
| NZ (1) | NZ507745A (no) |
| PL (1) | PL343710A1 (no) |
| SK (1) | SK16212000A3 (no) |
| TR (1) | TR200003157T2 (no) |
| WO (1) | WO1999055372A1 (no) |
| ZA (1) | ZA200005922B (no) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6875773B1 (en) | 1998-05-29 | 2005-04-05 | Ben M. Dunn | Combination therapy for treatment of FIV infection |
| CA2374198A1 (en) * | 1998-05-29 | 1999-12-02 | Maki Arai | Combination therapy for treatment of fiv infection |
| GB9820417D0 (en) * | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
| US7074417B2 (en) * | 2000-10-13 | 2006-07-11 | Advancis Pharmaceutical Corporation | Multiple-delayed release anti-viral product, use and formulation thereof |
| DE60219965T2 (de) * | 2002-04-23 | 2008-01-17 | Lupin Ltd., Mumbai | Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine |
| AR040242A1 (es) * | 2002-06-04 | 2005-03-23 | Glaxo Group Ltd | Composiciones farmaceuticas |
| CN100335125C (zh) * | 2003-06-03 | 2007-09-05 | 上海现代药物制剂工程研究中心 | 杀毒抗菌用长效干扰素喷鼻粉剂 |
| US20110104267A1 (en) * | 2005-04-25 | 2011-05-05 | Aurobindo Pharma Limited | Pharmaceutical compositions of antiretrovirals |
| WO2007013047A2 (en) * | 2005-07-29 | 2007-02-01 | Ranbaxy Laboratories Limited | Water-dispersible anti-retroviral pharmaceutical compositions |
| ES2279707B1 (es) * | 2005-11-10 | 2008-06-01 | Combino Pharm, S.L. | Formulaciones orales que comprenden 3'-azidonucleosidos. |
| CN101878032A (zh) * | 2007-10-02 | 2010-11-03 | 埃默里大学 | 齐多夫定和针对hiv聚合酶中k65r突变选择的药剂的强力组合 |
| WO2009092002A1 (en) * | 2008-01-17 | 2009-07-23 | Duquesne University Of The Holy Spirit | Antiretroviral drug formulations for treatment of children exposed to hiv/aids |
| UA105556C2 (uk) * | 2010-01-27 | 2014-05-26 | Віів Гелскер Компані | Комбінація сполук, що містить інгібітори віл інтегрази з іншими терапевтичними агентами |
| CN104203275A (zh) | 2010-06-09 | 2014-12-10 | 疫苗技术股份有限公司 | 用于增强抗逆转录病毒治疗的hiv感染者的治疗性免疫 |
| IN2014MN01907A (no) | 2012-03-05 | 2015-07-10 | Cipla Ltd | |
| US10004721B2 (en) | 2012-10-23 | 2018-06-26 | Cipla Limited | Pharmaceutical antiretroviral composition |
| SMT202400092T1 (it) | 2013-06-13 | 2024-05-14 | Akebia Therapeutics Inc | Composizioni e metodi per il trattamento dell'anemia |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY115461A (en) * | 1995-03-30 | 2003-06-30 | Wellcome Found | Synergistic combinations of zidovudine, 1592u89 and 3tc |
| GB9622681D0 (en) * | 1996-10-31 | 1997-01-08 | Glaxo Group Ltd | Pharmaceutical compositions |
-
1998
- 1998-04-29 GB GBGB9809213.3A patent/GB9809213D0/en not_active Ceased
-
1999
- 1999-04-26 IL IL13918199A patent/IL139181A0/xx unknown
- 1999-04-26 HR HR20000732A patent/HRP20000732A2/hr not_active Application Discontinuation
- 1999-04-26 JP JP2000545569A patent/JP2002512979A/ja active Pending
- 1999-04-26 ID IDW20002479A patent/ID26955A/id unknown
- 1999-04-26 TR TR2000/03157T patent/TR200003157T2/xx unknown
- 1999-04-26 PL PL99343710A patent/PL343710A1/xx unknown
- 1999-04-26 CA CA002330391A patent/CA2330391A1/en not_active Abandoned
- 1999-04-26 NZ NZ507745A patent/NZ507745A/en unknown
- 1999-04-26 BR BR9910071-1A patent/BR9910071A/pt not_active IP Right Cessation
- 1999-04-26 SK SK1621-2000A patent/SK16212000A3/sk unknown
- 1999-04-26 EA EA200000997A patent/EA200000997A1/ru unknown
- 1999-04-26 CN CN99807983A patent/CN1411380A/zh active Pending
- 1999-04-26 EP EP99924822A patent/EP1083932A1/en not_active Withdrawn
- 1999-04-26 KR KR1020007012021A patent/KR20010043128A/ko not_active Withdrawn
- 1999-04-26 EE EEP200000646A patent/EE200000646A/xx unknown
- 1999-04-26 AP APAP/P/2000/001971A patent/AP2000001971A0/en unknown
- 1999-04-26 HU HU0101622A patent/HUP0101622A3/hu unknown
- 1999-04-26 AU AU41355/99A patent/AU4135599A/en not_active Abandoned
- 1999-04-26 WO PCT/EP1999/002794 patent/WO1999055372A1/en not_active Ceased
-
2000
- 2000-10-20 IS IS5675A patent/IS5675A/is unknown
- 2000-10-23 ZA ZA200005922A patent/ZA200005922B/xx unknown
- 2000-10-27 NO NO20005418A patent/NO20005418L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200005922B (en) | 2001-10-23 |
| CA2330391A1 (en) | 1999-11-04 |
| ID26955A (id) | 2001-02-22 |
| NO20005418L (no) | 2000-11-29 |
| HRP20000732A2 (en) | 2001-02-28 |
| EA200000997A1 (ru) | 2001-06-25 |
| EE200000646A (et) | 2002-04-15 |
| HUP0101622A2 (hu) | 2002-03-28 |
| JP2002512979A (ja) | 2002-05-08 |
| NZ507745A (en) | 2004-07-30 |
| WO1999055372A1 (en) | 1999-11-04 |
| EP1083932A1 (en) | 2001-03-21 |
| SK16212000A3 (sk) | 2001-07-10 |
| NO20005418D0 (no) | 2000-10-27 |
| HUP0101622A3 (en) | 2003-09-29 |
| BR9910071A (pt) | 2000-12-26 |
| TR200003157T2 (tr) | 2001-01-22 |
| GB9809213D0 (en) | 1998-07-01 |
| CN1411380A (zh) | 2003-04-16 |
| IS5675A (is) | 2000-10-20 |
| AU4135599A (en) | 1999-11-16 |
| KR20010043128A (ko) | 2001-05-25 |
| IL139181A0 (en) | 2001-11-25 |
| PL343710A1 (en) | 2001-08-27 |
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