AP2006003763A0 - Macrocyclic compounds as inhibitors of viral replication - Google Patents

Macrocyclic compounds as inhibitors of viral replication

Info

Publication number
AP2006003763A0
AP2006003763A0 AP2006003763A AP2006003763A AP2006003763A0 AP 2006003763 A0 AP2006003763 A0 AP 2006003763A0 AP 2006003763 A AP2006003763 A AP 2006003763A AP 2006003763 A AP2006003763 A AP 2006003763A AP 2006003763 A0 AP2006003763 A0 AP 2006003763A0
Authority
AP
ARIPO
Prior art keywords
inhibitors
viral replication
macrocyclic compounds
macrocyclic
compounds
Prior art date
Application number
AP2006003763A
Other languages
English (en)
Inventor
Steven Wade Andrews
Lawrence M Blatt
Kevin R Condroski
George Andrew Doherty
Yutong Jiang
John Anthony Josey
April Layne Kennedy
Machender R Madduru
Peter John Stengel
Steven M Wenglowsky
Original Assignee
Intermune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermune Inc filed Critical Intermune Inc
Publication of AP2006003763A0 publication Critical patent/AP2006003763A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AP2006003763A 2004-03-30 2005-03-29 Macrocyclic compounds as inhibitors of viral replication AP2006003763A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US55816104P 2004-03-30 2004-03-30
US56241804P 2004-04-14 2004-04-14
US61238104P 2004-09-22 2004-09-22
US61246004P 2004-09-22 2004-09-22

Publications (1)

Publication Number Publication Date
AP2006003763A0 true AP2006003763A0 (en) 2006-10-31

Family

ID=35005653

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003763A AP2006003763A0 (en) 2004-03-30 2005-03-29 Macrocyclic compounds as inhibitors of viral replication

Country Status (16)

Country Link
EP (1) EP1749007A2 (fr)
JP (1) JP4950026B2 (fr)
AP (1) AP2006003763A0 (fr)
AR (1) AR050321A1 (fr)
AU (1) AU2005228894B9 (fr)
BR (1) BRPI0509467A (fr)
CA (1) CA2560897C (fr)
CU (1) CU23787B7 (fr)
EA (1) EA012389B1 (fr)
EC (1) ECSP066959A (fr)
GE (1) GEP20104926B (fr)
IL (1) IL177917A0 (fr)
MA (1) MA28548B1 (fr)
NO (1) NO20064933L (fr)
NZ (1) NZ549697A (fr)
WO (1) WO2005095403A2 (fr)

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US7741281B2 (en) 2005-11-03 2010-06-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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US7935670B2 (en) 2006-07-11 2011-05-03 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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Also Published As

Publication number Publication date
NO20064933L (no) 2006-12-15
BRPI0509467A (pt) 2007-09-11
AU2005228894A1 (en) 2005-10-13
MA28548B1 (fr) 2007-04-03
IL177917A0 (en) 2006-12-31
EP1749007A2 (fr) 2007-02-07
AR050321A1 (es) 2006-10-18
ECSP066959A (es) 2006-12-20
JP4950026B2 (ja) 2012-06-13
AU2005228894B9 (en) 2011-10-13
NZ549697A (en) 2009-12-24
EA012389B1 (ru) 2009-10-30
CU20090209A7 (es) 2011-04-26
JP2007531749A (ja) 2007-11-08
WO2005095403A3 (fr) 2005-12-01
EA200601467A1 (ru) 2007-06-29
AU2005228894B2 (en) 2011-08-25
CA2560897C (fr) 2012-06-12
CA2560897A1 (fr) 2005-10-13
CU23787B7 (es) 2012-03-15
WO2005095403A2 (fr) 2005-10-13
GEP20104926B (en) 2010-03-25

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