AP2008004568A0 - 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof - Google Patents

2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof

Info

Publication number
AP2008004568A0
AP2008004568A0 AP2008004568A AP2008004568A AP2008004568A0 AP 2008004568 A0 AP2008004568 A0 AP 2008004568A0 AP 2008004568 A AP2008004568 A AP 2008004568A AP 2008004568 A AP2008004568 A AP 2008004568A AP 2008004568 A0 AP2008004568 A0 AP 2008004568A0
Authority
AP
ARIPO
Prior art keywords
carbamide
preparation
therapeutic use
phenylthiazole derivatives
phenylthiazole
Prior art date
Application number
AP2008004568A
Other languages
English (en)
Inventor
Pierre Fraisse
Samir Jegham
Pierre Casellas
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of AP2008004568A0 publication Critical patent/AP2008004568A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AP2008004568A 2006-01-06 2007-01-04 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof AP2008004568A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0600117A FR2895989B1 (fr) 2006-01-06 2006-01-06 Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
PCT/FR2007/000007 WO2007077394A1 (fr) 2006-01-06 2007-01-04 Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
AP2008004568A0 true AP2008004568A0 (en) 2008-08-31

Family

ID=36940477

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2008004568A AP2008004568A0 (en) 2006-01-06 2007-01-04 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof

Country Status (23)

Country Link
US (1) US7825112B2 (fr)
EP (1) EP1984361A1 (fr)
JP (1) JP2009525951A (fr)
KR (1) KR20080082970A (fr)
CN (1) CN101365698A (fr)
AP (1) AP2008004568A0 (fr)
AR (1) AR059129A1 (fr)
AU (1) AU2007203998A1 (fr)
BR (1) BRPI0706305A2 (fr)
CA (1) CA2632854A1 (fr)
CR (1) CR10098A (fr)
DO (1) DOP2007000004A (fr)
EA (1) EA200870157A1 (fr)
EC (1) ECSP088574A (fr)
FR (1) FR2895989B1 (fr)
GT (1) GT200700002A (fr)
IL (1) IL191892A0 (fr)
MA (1) MA30179B1 (fr)
NO (1) NO20083352L (fr)
PE (1) PE20070816A1 (fr)
TN (1) TNSN08242A1 (fr)
TW (1) TW200738703A (fr)
WO (1) WO2007077394A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2854158B1 (fr) 2003-04-25 2006-11-17 Sanofi Synthelabo Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique
FR2872813B1 (fr) 2004-07-09 2007-01-19 Sanofi Synthelabo Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
FR2876692B1 (fr) 2004-10-19 2007-02-23 Sanofi Aventis Sa Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2406634A1 (fr) 1977-10-19 1979-05-18 Fabre Sa Pierre Immunostimulants derives d'amino thiazoles
WO1987001706A2 (fr) 1985-09-12 1987-03-26 The Upjohn Company Amino-steroides c20 a c26
FR2677356B1 (fr) 1991-06-05 1995-03-17 Sanofi Sa Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant.
WO1993000342A1 (fr) * 1991-06-21 1993-01-07 Boehringer Mannheim Italia S.P.A. 2-amino-4-aryl-thiazoles presentant des activites antiasthmatique et anti-inflammatoire sur les voies respiratoires
US6506751B1 (en) 1999-11-12 2003-01-14 Millennium Pharmaceuticals, Inc. Thiazolidinone compounds useful as chemokine inhibitors
US6852752B2 (en) 1999-12-17 2005-02-08 Vicuron Pharmaceuticals Inc. Urea compounds, compositions and methods of use and preparation
US6797820B2 (en) 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
US7132546B2 (en) 2000-12-22 2006-11-07 Ishihara Sangyo Kaisha, Ltd. Aniline derivatives or salts thereof and cytokine production inhibitors containing the same
WO2003015778A1 (fr) 2001-08-17 2003-02-27 Merck & Co., Inc. Inhibiteurs de tyrosine kinase
WO2003057145A2 (fr) 2001-12-31 2003-07-17 Guilford Pharmaceuticals Inc. 4,9-dihydrocyclopenta[imn]phenanthridine-5-ones substitues, leurs derives et leurs utilisations
TW200403058A (en) 2002-04-19 2004-03-01 Bristol Myers Squibb Co Heterocyclo inhibitors of potassium channel function
JPWO2003104230A1 (ja) 2002-06-07 2005-10-06 協和醗酵工業株式会社 二環性ピリミジン誘導体
FR2854158B1 (fr) 2003-04-25 2006-11-17 Sanofi Synthelabo Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique
FR2872813B1 (fr) 2004-07-09 2007-01-19 Sanofi Synthelabo Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
FR2876692B1 (fr) 2004-10-19 2007-02-23 Sanofi Aventis Sa Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique
US7906645B2 (en) * 2004-12-24 2011-03-15 Astrazeneca Ab Heterocyclic compounds as ccr2b antagonists
US8173638B2 (en) * 2006-11-21 2012-05-08 Boehringer Ingelheim International Gmbh Compounds which modulate the CB2 receptor

Also Published As

Publication number Publication date
CA2632854A1 (fr) 2007-07-12
IL191892A0 (en) 2008-12-29
CN101365698A (zh) 2009-02-11
GT200700002A (es) 2007-08-20
FR2895989A1 (fr) 2007-07-13
EP1984361A1 (fr) 2008-10-29
CR10098A (es) 2008-11-26
EA200870157A1 (ru) 2009-12-30
WO2007077394A1 (fr) 2007-07-12
NO20083352L (no) 2008-07-30
ECSP088574A (es) 2008-07-30
PE20070816A1 (es) 2007-08-17
BRPI0706305A2 (pt) 2011-03-22
MA30179B1 (fr) 2009-01-02
TW200738703A (en) 2007-10-16
DOP2007000004A (es) 2007-07-31
US20090018117A1 (en) 2009-01-15
TNSN08242A1 (en) 2009-10-30
FR2895989B1 (fr) 2010-04-30
JP2009525951A (ja) 2009-07-16
AU2007203998A1 (en) 2007-07-12
KR20080082970A (ko) 2008-09-12
AR059129A1 (es) 2008-03-12
US7825112B2 (en) 2010-11-02

Similar Documents

Publication Publication Date Title
SI2069342T1 (sl) Derivati aril fenil imidazo a piridinov njihova priprava in njihova terapevtska uporaba
IL204663A0 (en) Nicotinamide derivatives, preparastion thereof and therapeutic use thereof
ZA201100210B (en) Pyridino-pyridinone derivatives,preparation thereof,and therapeutic use thereof
IL180284A0 (en) 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
IL180682A0 (en) N-hydroxamide derivatives, their preparation and use
IL201471A0 (en) Triazolopyridine carboxamide derivatives and triazolopyrimidine carboxamide derivatives, preparation thereof and therapeutic use thereof
EP2157093A4 (fr) Dérivés pyrrolo-azotés hétérocycliques, leur préparation et leur utilisation pharmaceutique
ZA200900228B (en) N-(aminoheteroaryl)-1H-indole-2-carboxamide derivatives, preparation thereof and therapeutic use thereof
SI2146991T1 (sl) Derivati triazolopiridin karboksamidov njihova priprava in njihova terapevtska uporaba
ZA201002307B (en) Quinazolinedione derivatives,preparation thereof and therapeutic uses thereof
IL180770A0 (en) Oxopiperidine derivatives, preparation and therapeutic use thereof
IL201450A0 (en) Triazolopyridine carboxamide derivatives and triazolopyrimidine carboxamide derivatives, preparation thereof and therapeutic use thereof
IL178402A0 (en) 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof
IL192427A0 (en) Derivatives of sulindac, use thereof and preparation thereof
IL180797A0 (en) Amino-tropane derivatives, preparation thereof and therapeutic use thereof
ZA200703876B (en) 2-amido -4-phenylthiazole derivatives, the preparation and therapeutic use thereof
IL207629A0 (en) Novel 3-aminoalkyl-1,3-dihydro-2h-indol-2-one derivatives, preparation thereof and therapeutic use thereof
PL1988090T3 (pl) Pochodne kwasu imidazolo-5-karboksylowego, sposoby przygotowania i ich zastosowanie
IL190519A0 (en) 6-heteroarylpyridoindolone derivatives, their preparation and therapeutic use thereof
IL198481A0 (en) Pyrrole derivatives, preparation use of the same in therapy
TWI350287B (en) Acylaminothiazole derivatives, their preparation and their therapeutic application
TWI366566B (en) Tricyclic n-heteroarylcarboxamide derivatives, preparation thereof and therapeutic use thereof
PL2106401T3 (pl) Pochodne pirolopirydyno-2-karboksyamidów, ich wytwarzanie i ich zastosowanie w lecznictwie
IL191892A0 (en) 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
IL202474A0 (en) 1-benzylpyrazole derivatives, preparation thereof and therapeutic use thereof