AP2012006242A0 - Anticoagulant antidotes. - Google Patents

Anticoagulant antidotes.

Info

Publication number: AP2012006242A0
Authority: AP; ARIPO
Prior art keywords: antidotes; anticoagulant; anticoagulant antidotes
Prior art date: 2010-01-20

Application number

AP2012006242A

Other languages

English (en)

Inventor

Joanne Van Ryn

Nobert Hauel

Tobias Litzenburger

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-01-20

Filing date

2011-01-20

Publication date

2012-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42061991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2012006242(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-01-20 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2012-04-30 Publication of AP2012006242A0 publication Critical patent/AP2012006242A0/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39583—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials not provided for elsewhere, e.g. haptens, coenzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Urology & Nephrology (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Diabetes (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Physics & Mathematics (AREA)
Mycology (AREA)
Food Science & Technology (AREA)
Analytical Chemistry (AREA)
Toxicology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AP2012006242A 2010-01-20 2011-01-20 Anticoagulant antidotes. AP2012006242A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP10151239		2010-01-20
US38391410P	2010-09-17	2010-09-17
PCT/EP2011/050749 WO2011089183A2 (en)	2010-01-20	2011-01-20	Anticoagulant antidotes

Publications (1)

Publication Number	Publication Date
AP2012006242A0 true AP2012006242A0 (en)	2012-04-30

Family

ID=42061991

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2012006242A AP2012006242A0 (en)	2010-01-20	2011-01-20	Anticoagulant antidotes.

Country Status (43)

Country	Link
US (3)	US8486398B2 (lt)
EP (2)	EP3195876A1 (lt)
JP (2)	JP5575923B2 (lt)
KR (1)	KR101781787B1 (lt)
CN (1)	CN102711813B (lt)
AP (1)	AP2012006242A0 (lt)
AR (1)	AR079944A1 (lt)
AU (1)	AU2011208719C1 (lt)
BR (1)	BR112012018021B1 (lt)
CA (1)	CA2787566A1 (lt)
CO (1)	CO6571889A2 (lt)
CY (2)	CY1118875T1 (lt)
DK (1)	DK2525812T3 (lt)
EA (1)	EA028371B1 (lt)
EC (1)	ECSP12012105A (lt)
ES (1)	ES2614992T3 (lt)
FR (1)	FR17C1026I2 (lt)
GE (1)	GEP20156341B (lt)
HR (1)	HRP20170613T1 (lt)
HU (2)	HUE032263T2 (lt)
IL (1)	IL219427B (lt)
LT (2)	LT2525812T (lt)
LU (1)	LUC00028I2 (lt)
MA (1)	MA33936B1 (lt)
ME (1)	ME02602B (lt)
MX (1)	MX2012008360A (lt)
MY (1)	MY162323A (lt)
NL (1)	NL300882I2 (lt)
NO (2)	NO2017034I1 (lt)
NZ (1)	NZ599508A (lt)
PE (1)	PE20121516A1 (lt)
PH (1)	PH12012501493A1 (lt)
PL (1)	PL2525812T3 (lt)
PT (1)	PT2525812T (lt)
RS (1)	RS55683B1 (lt)
SG (1)	SG182552A1 (lt)
SI (1)	SI2525812T1 (lt)
TN (1)	TN2012000366A1 (lt)
TW (1)	TWI513466B (lt)
UA (1)	UA110470C2 (lt)
UY (1)	UY33196A (lt)
WO (1)	WO2011089183A2 (lt)
ZA (1)	ZA201202876B (lt)

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WO2012130834A1 (en) *	2011-03-30	2012-10-04	Boehringer Ingelheim International Gmbh	Anticoagulant antidotes
CN104080772B (zh)	2011-11-29	2016-10-05	佩罗斯菲尔股份有限公司	抗凝血逆转剂
PE20160533A1 (es)	2013-03-14	2016-06-09	Bayer Healthcare Llc	Anticuerpos monoclonales contra antitrombina beta que forma complejos con heparina
JP2016539926A (ja) *	2013-10-25	2016-12-22	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	抗凝血薬の解毒剤
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WO2019124468A1 (ja) *	2017-12-24	2019-06-27	ノイルイミューン・バイオテック株式会社	ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞
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EP3873916B8 (en)	2018-10-29	2025-03-26	Shanghai Synergy Pharmaceutical Sciences, Ltd.	Novel dipeptide compounds and uses thereof
US12251377B2 (en)	2019-03-06	2025-03-18	University Of Rochester	Anticoagulant compositions and uses thereof
CN114306245A (zh)	2020-09-29	2022-04-12	深圳市药欣生物科技有限公司	无定形固体分散体的药物组合物及其制备方法
TW202321311A (zh) *	2021-08-02	2023-06-01	日商諾伊爾免疫生物科技股份有限公司	與scFv等之連接子結合的抗體
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2011
- 2011-01-19 AR ARP110100179A patent/AR079944A1/es active IP Right Grant
- 2011-01-19 TW TW100102006A patent/TWI513466B/zh active
- 2011-01-20 MY MYPI2012002840A patent/MY162323A/en unknown
- 2011-01-20 AP AP2012006242A patent/AP2012006242A0/xx unknown
- 2011-01-20 PT PT117034108T patent/PT2525812T/pt unknown
- 2011-01-20 UA UAA201209779A patent/UA110470C2/ru unknown
- 2011-01-20 PH PH1/2012/501493A patent/PH12012501493A1/en unknown
- 2011-01-20 SI SI201131156A patent/SI2525812T1/sl unknown
- 2011-01-20 NZ NZ599508A patent/NZ599508A/en unknown
- 2011-01-20 RS RS20170195A patent/RS55683B1/sr unknown
- 2011-01-20 UY UY0001033196A patent/UY33196A/es active IP Right Grant
- 2011-01-20 CA CA2787566A patent/CA2787566A1/en not_active Abandoned
- 2011-01-20 WO PCT/EP2011/050749 patent/WO2011089183A2/en not_active Ceased
- 2011-01-20 PE PE2012000997A patent/PE20121516A1/es active IP Right Grant
- 2011-01-20 PL PL11703410T patent/PL2525812T3/pl unknown
- 2011-01-20 GE GEAP201112836A patent/GEP20156341B/en unknown
- 2011-01-20 MA MA35080A patent/MA33936B1/fr unknown
- 2011-01-20 HU HUE11703410A patent/HUE032263T2/en unknown
- 2011-01-20 MX MX2012008360A patent/MX2012008360A/es active IP Right Grant
- 2011-01-20 HR HRP20170613TT patent/HRP20170613T1/hr unknown
- 2011-01-20 KR KR1020127019086A patent/KR101781787B1/ko active Active
- 2011-01-20 LT LTEP11703410.8T patent/LT2525812T/lt unknown
- 2011-01-20 ES ES11703410.8T patent/ES2614992T3/es active Active
- 2011-01-20 DK DK11703410.8T patent/DK2525812T3/en active
- 2011-01-20 EA EA201201016A patent/EA028371B1/ru active Protection Beyond IP Right Term
- 2011-01-20 JP JP2012549355A patent/JP5575923B2/ja active Active
- 2011-01-20 ME MEP-2017-29A patent/ME02602B/me unknown
- 2011-01-20 AU AU2011208719A patent/AU2011208719C1/en active Active
- 2011-01-20 BR BR112012018021-5A patent/BR112012018021B1/pt active IP Right Grant
- 2011-01-20 SG SG2012052445A patent/SG182552A1/en unknown
- 2011-01-20 CN CN201180006616.4A patent/CN102711813B/zh active Active
- 2011-01-20 EP EP16205771.5A patent/EP3195876A1/en not_active Withdrawn
- 2011-01-20 EP EP11703410.8A patent/EP2525812B1/en active Active
- 2011-01-20 US US13/010,403 patent/US8486398B2/en active Active
2012
- 2012-04-19 ZA ZA2012/02876A patent/ZA201202876B/en unknown
- 2012-04-25 IL IL219427A patent/IL219427B/en active IP Right Grant
- 2012-07-18 TN TNP2012000366A patent/TN2012000366A1/en unknown
- 2012-07-23 CO CO12123109A patent/CO6571889A2/es active IP Right Grant
- 2012-08-14 EC ECSP12012105 patent/ECSP12012105A/es unknown
2013
- 2013-06-13 US US13/916,994 patent/US9034822B2/en active Active
2014
- 2014-07-02 JP JP2014136811A patent/JP2014210794A/ja active Pending
2015
- 2015-04-13 US US14/684,576 patent/US20150210778A1/en not_active Abandoned
2017
- 2017-03-22 CY CY20171100361T patent/CY1118875T1/el unknown
- 2017-07-06 NL NL300882C patent/NL300882I2/nl unknown
- 2017-07-10 CY CY2017025C patent/CY2017025I2/el unknown
- 2017-07-10 FR FR17C1026C patent/FR17C1026I2/fr active Active
- 2017-07-10 LT LTPA2017021C patent/LTC2525812I2/lt unknown
- 2017-07-11 NO NO2017034C patent/NO2017034I1/no unknown
- 2017-07-12 LU LU00028C patent/LUC00028I2/fr unknown
- 2017-07-13 HU HUS1700030C patent/HUS1700030I1/hu unknown
2022
- 2022-08-12 NO NO2022036C patent/NO2022036I1/no unknown

Also Published As

Publication number	Publication date
WO2011089183A3 (en)	2011-11-17
LTPA2017021I1 (lt)	2017-07-25
EA201201016A1 (ru)	2013-02-28
RS55683B1 (sr)	2017-07-31
UA110470C2 (ru)	2016-01-12
ES2614992T3 (es)	2017-06-02
LTC2525812I2 (lt)	2019-05-10
US9034822B2 (en)	2015-05-19
AR079944A1 (es)	2012-02-29
PT2525812T (pt)	2017-04-26
DK2525812T3 (en)	2017-02-27
LUC00028I1 (lt)	2017-07-14
CN102711813A (zh)	2012-10-03
AU2011208719A1 (en)	2012-05-17
TW201136606A (en)	2011-11-01
SI2525812T1 (sl)	2017-05-31
EP3195876A1 (en)	2017-07-26
AU2011208719C1 (en)	2017-07-13
ECSP12012105A (es)	2012-10-30
ZA201202876B (en)	2012-12-27
MA33936B1 (fr)	2013-01-02
LUC00028I2 (lt)	2017-09-25
NO2017034I1 (no)	2017-07-11
ME02602B (me)	2017-06-20
US20120027780A1 (en)	2012-02-02
CO6571889A2 (es)	2012-11-30
EP2525812A2 (en)	2012-11-28
JP2014210794A (ja)	2014-11-13
UY33196A (es)	2011-08-31
MY162323A (en)	2017-05-31
KR20120128126A (ko)	2012-11-26
EP2525812B1 (en)	2017-01-18
HUE032263T2 (en)	2017-09-28
PE20121516A1 (es)	2012-11-24
PH12012501493A1 (en)	2012-10-22
US20150210778A1 (en)	2015-07-30
CN102711813B (zh)	2015-03-04
US20130289248A1 (en)	2013-10-31
KR101781787B1 (ko)	2017-09-26
MX2012008360A (es)	2012-08-08
HK1173957A1 (en)	2013-05-31
CY1118875T1 (el)	2018-01-10
PL2525812T3 (pl)	2017-07-31
NL300882I2 (nl)	2017-07-20
NO2022036I1 (no)	2022-08-12
TWI513466B (zh)	2015-12-21
TN2012000366A1 (en)	2014-01-30
IL219427B (en)	2018-05-31
JP5575923B2 (ja)	2014-08-20
IL219427A0 (en)	2012-06-28
JP2013517317A (ja)	2013-05-16
CY2017025I1 (el)	2017-11-14
GEP20156341B (en)	2015-08-10
US8486398B2 (en)	2013-07-16
CY2017025I2 (el)	2017-11-14
FR17C1026I2 (fr)	2018-07-20
FR17C1026I1 (fr)	2017-09-08
HRP20170613T1 (hr)	2017-06-30
SG182552A1 (en)	2012-08-30
BR112012018021B1 (pt)	2020-12-08
LT2525812T (lt)	2017-02-27
EA028371B1 (ru)	2017-11-30
NZ599508A (en)	2014-05-30
HUS1700030I1 (hu)	2017-08-28
WO2011089183A2 (en)	2011-07-28
CA2787566A1 (en)	2011-07-28
BR112012018021A2 (pt)	2017-06-20

Publication	Publication Date	Title
AP2012006242A0 (en)	2012-04-30	Anticoagulant antidotes.
GB201106792D0 (en)	2011-06-01	.
GB201206830D0 (en)	2012-05-30	.
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GB201118961D0 (en)	2011-12-14	.
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AP2013007046A0 (en)	2013-08-31	Anticoagulant antidotes
GB201122114D0 (en)	2012-02-01	.
GB201104448D0 (en)	2011-04-27	.
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AU2011100252A4 (en)	2011-04-14	Catch the Coasters
GB201007038D0 (en)	2010-06-09	.
GB201010220D0 (en)	2010-07-21	.
GB201016067D0 (en)	2010-11-10	.