AP2012006242A0 - Anticoagulant antidotes. - Google Patents

Anticoagulant antidotes.

Info

Publication number: AP2012006242A0
Authority: AP; ARIPO
Prior art keywords: antidotes; anticoagulant; anticoagulant antidotes
Prior art date: 2010-01-20

Application number

AP2012006242A

Other languages

English (en)

Inventor

Joanne Van Ryn

Nobert Hauel

Tobias Litzenburger

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-01-20

Filing date

2011-01-20

Publication date

2012-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42061991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2012006242(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-01-20 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2012-04-30 Publication of AP2012006242A0 publication Critical patent/AP2012006242A0/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39583—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials not provided for elsewhere, e.g. haptens, coenzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Urology & Nephrology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Pathology (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Cell Biology (AREA)
Mycology (AREA)
General Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Toxicology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AP2012006242A 2010-01-20 2011-01-20 Anticoagulant antidotes. AP2012006242A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP10151239		2010-01-20
US38391410P	2010-09-17	2010-09-17
PCT/EP2011/050749 WO2011089183A2 (en)	2010-01-20	2011-01-20	Anticoagulant antidotes

Publications (1)

Publication Number	Publication Date
AP2012006242A0 true AP2012006242A0 (en)	2012-04-30

Family

ID=42061991

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2012006242A AP2012006242A0 (en)	2010-01-20	2011-01-20	Anticoagulant antidotes.

Country Status (43)

Country	Link
US (3)	US8486398B2 (lt)
EP (2)	EP3195876A1 (lt)
JP (2)	JP5575923B2 (lt)
KR (1)	KR101781787B1 (lt)
CN (1)	CN102711813B (lt)
AP (1)	AP2012006242A0 (lt)
AR (1)	AR079944A1 (lt)
AU (1)	AU2011208719C1 (lt)
BR (1)	BR112012018021B1 (lt)
CA (1)	CA2787566A1 (lt)
CO (1)	CO6571889A2 (lt)
CY (2)	CY1118875T1 (lt)
DK (1)	DK2525812T3 (lt)
EA (1)	EA028371B1 (lt)
EC (1)	ECSP12012105A (lt)
ES (1)	ES2614992T3 (lt)
FR (1)	FR17C1026I2 (lt)
GE (1)	GEP20156341B (lt)
HR (1)	HRP20170613T1 (lt)
HU (2)	HUE032263T2 (lt)
IL (1)	IL219427B (lt)
LT (2)	LT2525812T (lt)
LU (1)	LUC00028I2 (lt)
MA (1)	MA33936B1 (lt)
ME (1)	ME02602B (lt)
MX (1)	MX2012008360A (lt)
MY (1)	MY162323A (lt)
NL (1)	NL300882I2 (lt)
NO (2)	NO2017034I1 (lt)
NZ (1)	NZ599508A (lt)
PE (1)	PE20121516A1 (lt)
PH (1)	PH12012501493A1 (lt)
PL (1)	PL2525812T3 (lt)
PT (1)	PT2525812T (lt)
RS (1)	RS55683B1 (lt)
SG (1)	SG182552A1 (lt)
SI (1)	SI2525812T1 (lt)
TN (1)	TN2012000366A1 (lt)
TW (1)	TWI513466B (lt)
UA (1)	UA110470C2 (lt)
UY (1)	UY33196A (lt)
WO (1)	WO2011089183A2 (lt)
ZA (1)	ZA201202876B (lt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI513466B (zh) *	2010-01-20	2015-12-21	Boehringer Ingelheim Int	抗凝血劑解毒劑
CA2858350A1 (en)	2011-01-14	2013-07-19	The Regents Of The University Of California	Therapeutic antibodies against ror-1 protein and methods for use of same
CN103619883A (zh) *	2011-01-19	2014-03-05	拜耳知识产权有限责任公司	凝血因子抑制剂的结合蛋白
PE20140964A1 (es) *	2011-03-30	2014-08-17	Boehringer Ingelheim Int	Antidotos anticoagulantes
WO2013082210A1 (en)	2011-11-29	2013-06-06	Perosphere Inc.	Anticoagulant reversal agents
US9593166B2 (en)	2013-03-14	2017-03-14	Bayer Healthcare Llc	Monoclonal antibodies against antithrombin β
WO2015059159A1 (en) *	2013-10-25	2015-04-30	Boehringer Ingelheim International Gmbh	Anticoagulant antidotes
TW201623331A (zh) *	2014-03-12	2016-07-01	普羅帝納生物科學公司	抗黑色素瘤細胞黏著分子（ｍｃａｍ）抗體類及使用彼等之相關方法
CN105223348A (zh) *	2014-05-26	2016-01-06	北京九强生物技术股份有限公司	人抗凝血酶iii的胶乳增强免疫比浊法检测试剂盒
EP2980218A1 (en) *	2014-07-30	2016-02-03	Rheinische Friedrich-Wilhelms-Universität Bonn	Aptamer thrombin complex for use as an antidote to direct acting thrombin inhibitors
EP3175245B1 (en) *	2014-07-31	2019-05-29	Haemonetics Corporation	Detection and classification of an anticoagulant using a clotting assay
WO2016044645A1 (en) *	2014-09-17	2016-03-24	Elmaleh David R	Anticoagulant derivatives for cardiovascular imaging
WO2016107605A1 (zh)	2014-12-31	2016-07-07	昆明积大制药股份有限公司	药物组合物及其制备方法
CN109078006B (zh)	2016-03-29	2021-04-20	深圳市药欣生物科技有限公司	一种帕布昔利布的药物制剂及其制备方法
US11879014B2 (en)	2017-03-17	2024-01-23	Tusk Therapeutics Ltd.	Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody
FI3730612T3 (fi) *	2017-12-24	2026-04-30	Noile Immune Biotech Inc	Immunokompetentti solu, joka ilmaisee erityisesti ihmisen mesoteliinin, il-7:n ja ccl19:n tunnistavan solukalvon molekyylin
AU2019233576A1 (en)	2018-03-13	2020-09-17	Cancer Research Technology Limited	Anti-CD25 for tumour specific cell depletion
WO2019217705A1 (en) *	2018-05-11	2019-11-14	Proplex Technologies, LLC	Binding proteins and chimeric antigen receptor t cells targeting gasp-1 granules and uses thereof
CN116813691B (zh)	2018-10-29	2024-04-12	丽珠医药集团股份有限公司	新的二肽类化合物及其用途
US12251377B2 (en)	2019-03-06	2025-03-18	University Of Rochester	Anticoagulant compositions and uses thereof
CN114306245A (zh)	2020-09-29	2022-04-12	深圳市药欣生物科技有限公司	无定形固体分散体的药物组合物及其制备方法
TW202321311A (zh) *	2021-08-02	2023-06-01	日商諾伊爾免疫生物科技股份有限公司	與scFv等之連接子結合的抗體
US11446286B1 (en) *	2022-02-28	2022-09-20	King Faisal University	Treatment of fungal infections using dabigatran etexilate
NL2036011B1 (en)	2023-10-12	2025-04-30	Synapse Res Institute	Molecules for reversing anti-coagulant activity of direct oral anticoagulants
WO2025149667A1 (en)	2024-01-12	2025-07-17	Pheon Therapeutics Ltd	Antibody drug conjugates and uses thereof

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6087380A (en)	1949-11-24	2000-07-11	Boehringer Ingelheim Pharma Kg	Disubstituted bicyclic heterocycles, the preparations and the use thereof as pharmaceutical compositions
WO1988001649A1 (en)	1986-09-02	1988-03-10	Genex Corporation	Single polypeptide chain binding molecules
ES2052027T5 (es)	1988-11-11	2005-04-16	Medical Research Council	Clonacion de secuencias de dominio variable de inmunoglobulina.
US5530101A (en) *	1988-12-28	1996-06-25	Protein Design Labs, Inc.	Humanized immunoglobulins
US5427908A (en)	1990-05-01	1995-06-27	Affymax Technologies N.V.	Recombinant library screening methods
ES2102007T3 (es) *	1992-01-23	1997-07-16	Merck Patent Gmbh	Proteinas de fusion de fragmentos de anticuerpo monomeras y dimeras.
DE4203965A1 (de)	1992-02-11	1993-08-12	Max Planck Gesellschaft	Antidot fuer hirudin und synthetische thrombininhibitoren
PT1621554E (pt)	1992-08-21	2009-07-13	Univ Bruxelles	Imunoglobtainas desprovidas de cadeias leves
JP3720353B2 (ja)	1992-12-04	2005-11-24	メディカルリサーチカウンシル	多価および多重特異性の結合タンパク質、それらの製造および使用
DE69420137T2 (de)	1993-06-03	1999-12-23	Therapeutic Antibodies, Inc.	Herstellung von antikörperfragmenten
AT404357B (de)	1995-06-13	1998-11-25	Immuno Ag	Prothrombin-derivate
DE19605126A1 (de)	1996-02-12	1997-08-14	Basf Ag	Thrombinmuteine als Antidot für Thrombininhibitoren
US6200955B1 (en)	1996-06-11	2001-03-13	Commonwealth Biotechnologies, Inc.	Heparin binding peptides
GB9625640D0 (en)	1996-12-10	1997-01-29	Celltech Therapeutics Ltd	Biological products
PE121699A1 (es) *	1997-02-18	1999-12-08	Boehringer Ingelheim Pharma	Heterociclos biciclicos disustituidos como inhibidores de la trombina
AU7266698A (en)	1997-04-30	1998-11-24	Enzon, Inc.	Polyalkylene oxide-modified single chain polypeptides
DE19729544A1 (de) *	1997-07-10	1999-01-14	Basf Ag	Ancrod spezifische monoklonale Antikörper, Antikörperfragmente, deren Mischung oder Derivate und deren Verwendung
US6440417B1 (en)	1998-11-06	2002-08-27	Conjuchem, Inc.	Antibodies to argatroban derivatives and their use in therapeutic and diagnostic treatments
US6624141B1 (en)	1999-03-17	2003-09-23	The Regents Of The University Of Michigan	Protamine fragment compositions and methods of use
EP1274720A4 (en)	2000-04-12	2004-08-18	Human Genome Sciences Inc	FUSION PROTEINS CONTAINING ALBUMIN
CN101684158A (zh)	2001-01-17	2010-03-31	特鲁比昂药品公司	结合域-免疫球蛋白融合蛋白
US20040097547A1 (en)	2001-04-16	2004-05-20	Taveras Arthur G.	3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
US20070031438A1 (en) *	2001-12-10	2007-02-08	Junghans Richard P	Antibodies as chimeric effector cell receptors against tumor antigens
US20050214857A1 (en)	2001-12-11	2005-09-29	Algonomics N.V.	Method for displaying loops from immunoglobulin domains in different contexts
EP1600459A3 (en)	2002-06-28	2005-12-07	Domantis Limited	Ligand
EP2284192A3 (en)	2002-11-08	2011-07-20	Ablynx N.V.	Camelidae antibodies for sublingual administration
SI1639011T1 (sl)	2003-06-30	2009-04-30	Domantis Ltd	Pegilirana protitelesa z enojno domeno (dAb)
EP2193196B1 (en) *	2007-09-28	2016-07-13	Portola Pharmaceuticals, Inc.	Antidotes for factor xa inhibitors and methods of using the same
AR070141A1 (es) *	2008-01-23	2010-03-17	Glenmark Pharmaceuticals Sa	Anticuerpos humanizados especificos para el factor von willebrand
BR112012004169A2 (pt)	2009-08-24	2016-03-29	Boehringer Ingelheim Int	intervenções de emergência com carvão vegetal ativado em superdosagem de etexilato de dabigatran
TWI513466B (zh)	2010-01-20	2015-12-21	Boehringer Ingelheim Int	抗凝血劑解毒劑

2011
- 2011-01-19 TW TW100102006A patent/TWI513466B/zh active
- 2011-01-19 AR ARP110100179A patent/AR079944A1/es active IP Right Grant
- 2011-01-20 WO PCT/EP2011/050749 patent/WO2011089183A2/en not_active Ceased
- 2011-01-20 JP JP2012549355A patent/JP5575923B2/ja active Active
- 2011-01-20 DK DK11703410.8T patent/DK2525812T3/en active
- 2011-01-20 HU HUE11703410A patent/HUE032263T2/en unknown
- 2011-01-20 PH PH1/2012/501493A patent/PH12012501493A1/en unknown
- 2011-01-20 SG SG2012052445A patent/SG182552A1/en unknown
- 2011-01-20 UA UAA201209779A patent/UA110470C2/ru unknown
- 2011-01-20 LT LTEP11703410.8T patent/LT2525812T/lt unknown
- 2011-01-20 CA CA2787566A patent/CA2787566A1/en not_active Abandoned
- 2011-01-20 MY MYPI2012002840A patent/MY162323A/en unknown
- 2011-01-20 MX MX2012008360A patent/MX2012008360A/es active IP Right Grant
- 2011-01-20 AP AP2012006242A patent/AP2012006242A0/xx unknown
- 2011-01-20 CN CN201180006616.4A patent/CN102711813B/zh active Active
- 2011-01-20 PE PE2012000997A patent/PE20121516A1/es active IP Right Grant
- 2011-01-20 ME MEP-2017-29A patent/ME02602B/me unknown
- 2011-01-20 BR BR112012018021-5A patent/BR112012018021B1/pt active IP Right Grant
- 2011-01-20 KR KR1020127019086A patent/KR101781787B1/ko active Active
- 2011-01-20 SI SI201131156A patent/SI2525812T1/sl unknown
- 2011-01-20 UY UY0001033196A patent/UY33196A/es active IP Right Grant
- 2011-01-20 PL PL11703410T patent/PL2525812T3/pl unknown
- 2011-01-20 EP EP16205771.5A patent/EP3195876A1/en not_active Withdrawn
- 2011-01-20 US US13/010,403 patent/US8486398B2/en active Active
- 2011-01-20 RS RS20170195A patent/RS55683B1/sr unknown
- 2011-01-20 NZ NZ599508A patent/NZ599508A/en unknown
- 2011-01-20 HR HRP20170613TT patent/HRP20170613T1/hr unknown
- 2011-01-20 ES ES11703410.8T patent/ES2614992T3/es active Active
- 2011-01-20 GE GEAP201112836A patent/GEP20156341B/en unknown
- 2011-01-20 AU AU2011208719A patent/AU2011208719C1/en active Active
- 2011-01-20 EA EA201201016A patent/EA028371B1/ru active Protection Beyond IP Right Term
- 2011-01-20 EP EP11703410.8A patent/EP2525812B1/en active Active
- 2011-01-20 MA MA35080A patent/MA33936B1/fr unknown
- 2011-01-20 PT PT117034108T patent/PT2525812T/pt unknown
2012
- 2012-04-19 ZA ZA2012/02876A patent/ZA201202876B/en unknown
- 2012-04-25 IL IL219427A patent/IL219427B/en active IP Right Grant
- 2012-07-18 TN TNP2012000366A patent/TN2012000366A1/en unknown
- 2012-07-23 CO CO12123109A patent/CO6571889A2/es active IP Right Grant
- 2012-08-14 EC ECSP12012105 patent/ECSP12012105A/es unknown
2013
- 2013-06-13 US US13/916,994 patent/US9034822B2/en active Active
2014
- 2014-07-02 JP JP2014136811A patent/JP2014210794A/ja active Pending
2015
- 2015-04-13 US US14/684,576 patent/US20150210778A1/en not_active Abandoned
2017
- 2017-03-22 CY CY20171100361T patent/CY1118875T1/el unknown
- 2017-07-06 NL NL300882C patent/NL300882I2/nl unknown
- 2017-07-10 FR FR17C1026C patent/FR17C1026I2/fr active Active
- 2017-07-10 CY CY2017025C patent/CY2017025I1/el unknown
- 2017-07-10 LT LTPA2017021C patent/LTC2525812I2/lt unknown
- 2017-07-11 NO NO2017034C patent/NO2017034I1/no unknown
- 2017-07-12 LU LU00028C patent/LUC00028I2/fr unknown
- 2017-07-13 HU HUS1700030C patent/HUS1700030I1/hu unknown
2022
- 2022-08-12 NO NO2022036C patent/NO2022036I1/no unknown

Also Published As

Publication number	Publication date
EA201201016A1 (ru)	2013-02-28
LTPA2017021I1 (lt)	2017-07-25
CA2787566A1 (en)	2011-07-28
JP5575923B2 (ja)	2014-08-20
TN2012000366A1 (en)	2014-01-30
SI2525812T1 (sl)	2017-05-31
MX2012008360A (es)	2012-08-08
SG182552A1 (en)	2012-08-30
MY162323A (en)	2017-05-31
TWI513466B (zh)	2015-12-21
NO2022036I1 (no)	2022-08-12
AU2011208719A1 (en)	2012-05-17
KR101781787B1 (ko)	2017-09-26
ES2614992T3 (es)	2017-06-02
US20150210778A1 (en)	2015-07-30
EP2525812B1 (en)	2017-01-18
CO6571889A2 (es)	2012-11-30
NZ599508A (en)	2014-05-30
EA028371B1 (ru)	2017-11-30
EP3195876A1 (en)	2017-07-26
AU2011208719C1 (en)	2017-07-13
ECSP12012105A (es)	2012-10-30
IL219427A0 (en)	2012-06-28
UA110470C2 (ru)	2016-01-12
FR17C1026I1 (fr)	2017-09-08
IL219427B (en)	2018-05-31
AR079944A1 (es)	2012-02-29
FR17C1026I2 (fr)	2018-07-20
BR112012018021B1 (pt)	2020-12-08
HUE032263T2 (en)	2017-09-28
MA33936B1 (fr)	2013-01-02
US9034822B2 (en)	2015-05-19
NO2017034I1 (no)	2017-07-11
PH12012501493A1 (en)	2012-10-22
US20130289248A1 (en)	2013-10-31
LUC00028I2 (lt)	2017-09-25
CY2017025I2 (el)	2017-11-14
ZA201202876B (en)	2012-12-27
DK2525812T3 (en)	2017-02-27
CN102711813A (zh)	2012-10-03
LTC2525812I2 (lt)	2019-05-10
WO2011089183A2 (en)	2011-07-28
JP2013517317A (ja)	2013-05-16
PL2525812T3 (pl)	2017-07-31
EP2525812A2 (en)	2012-11-28
CY1118875T1 (el)	2018-01-10
NL300882I2 (nl)	2017-07-20
PE20121516A1 (es)	2012-11-24
TW201136606A (en)	2011-11-01
HRP20170613T1 (hr)	2017-06-30
US8486398B2 (en)	2013-07-16
WO2011089183A3 (en)	2011-11-17
LUC00028I1 (lt)	2017-07-14
BR112012018021A2 (pt)	2017-06-20
PT2525812T (pt)	2017-04-26
KR20120128126A (ko)	2012-11-26
CY2017025I1 (el)	2017-11-14
RS55683B1 (sr)	2017-07-31
LT2525812T (lt)	2017-02-27
JP2014210794A (ja)	2014-11-13
UY33196A (es)	2011-08-31
US20120027780A1 (en)	2012-02-02
CN102711813B (zh)	2015-03-04
GEP20156341B (en)	2015-08-10
HUS1700030I1 (hu)	2017-08-28
HK1173957A1 (en)	2013-05-31
ME02602B (me)	2017-06-20

Publication	Publication Date	Title
HUS1700030I1 (hu)	2017-08-28	Véralvadásgátló-antidótumok
GB201106792D0 (en)	2011-06-01	.
GB201206830D0 (en)	2012-05-30	.
GB201104434D0 (en)	2011-04-27	.
GB201115796D0 (en)	2011-10-26	.
GB201118961D0 (en)	2011-12-14	.
GB201106766D0 (en)	2011-06-01	.
GB201118592D0 (en)	2011-12-07	.
AP2013007046A0 (en)	2013-08-31	Anticoagulant antidotes
GB201122114D0 (en)	2012-02-01	.
GB201104448D0 (en)	2011-04-27	.
GB201203063D0 (en)	2012-04-04	.
GB201104429D0 (en)	2011-04-27	.
GB201102141D0 (en)	2011-03-23	.
GB201115799D0 (en)	2011-10-26	.
GB201114750D0 (en)	2011-10-12	.
GB201202620D0 (en)	2012-03-28	.
GB201122259D0 (en)	2012-02-01	.
GB201119853D0 (en)	2011-12-28	.
GB201104430D0 (en)	2011-04-27	.
GB201117584D0 (en)	2011-11-23	.
AU2011100252A4 (en)	2011-04-14	Catch the Coasters
GB201008395D0 (en)	2010-07-07	.
GB201009456D0 (en)	2010-07-21	.
GB201011244D0 (en)	2010-08-18	.