AP2015008729A0 - Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods - Google Patents

Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods

Info

Publication number
AP2015008729A0
AP2015008729A0 AP2015008729A AP2015008729A AP2015008729A0 AP 2015008729 A0 AP2015008729 A0 AP 2015008729A0 AP 2015008729 A AP2015008729 A AP 2015008729A AP 2015008729 A AP2015008729 A AP 2015008729A AP 2015008729 A0 AP2015008729 A0 AP 2015008729A0
Authority
AP
ARIPO
Prior art keywords
timp
variants
compositions
methods
tissue inhibitor
Prior art date
Application number
AP2015008729A
Other languages
English (en)
Inventor
Mark Leo Michaels
Edward J Belouski
Randy Ira Hecht
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AP2015008729A0 publication Critical patent/AP2015008729A0/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
AP2015008729A 2013-03-14 2014-03-13 Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods AP2015008729A0 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361782613P 2013-03-14 2013-03-14
US201361798160P 2013-03-15 2013-03-15
US201361802988P 2013-03-18 2013-03-18
US201461940673P 2014-02-17 2014-02-17
PCT/US2014/026811 WO2014152012A2 (fr) 2013-03-14 2014-03-13 Variants d'inhibiteur tissulaire de la métalloprotéinase type iii (timp-3), compositions et procédés

Publications (1)

Publication Number Publication Date
AP2015008729A0 true AP2015008729A0 (en) 2015-09-30

Family

ID=50473803

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008729A AP2015008729A0 (en) 2013-03-14 2014-03-13 Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods

Country Status (20)

Country Link
US (3) US10189890B2 (fr)
EP (1) EP2970407B1 (fr)
JP (6) JP2016513666A (fr)
KR (1) KR102258564B1 (fr)
CN (2) CN111499733A (fr)
AP (1) AP2015008729A0 (fr)
AU (5) AU2014236683B2 (fr)
BR (1) BR112015022491A2 (fr)
CA (1) CA2906053C (fr)
CL (1) CL2015002663A1 (fr)
EA (1) EA034200B1 (fr)
IL (1) IL241246B (fr)
MX (1) MX380644B (fr)
PE (1) PE20151894A1 (fr)
PH (1) PH12015502059A1 (fr)
SG (2) SG11201507524TA (fr)
TN (1) TN2015000423A1 (fr)
TW (3) TWI685501B (fr)
WO (1) WO2014152012A2 (fr)
ZA (2) ZA201506746B (fr)

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MX382490B (es) * 2014-08-27 2025-03-13 Amgen Inc Variantes de inhibidor de tejido de metaloproteinasa tipo tres (timp-3), composiciones y metodos
WO2016061220A2 (fr) 2014-10-14 2016-04-21 Amgen Inc. Dispositif d'injection de médicament comportant des témoins visuels et sonores
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WO2016138434A1 (fr) 2015-02-27 2016-09-01 Amgen Inc. Dispositif d'administration de médicament ayant un mécanisme de protection d'aiguille présentant un seuil réglable de résistance au mouvement de l'élément de protection d'aiguille
WO2017039786A1 (fr) 2015-09-02 2017-03-09 Amgen Inc. Adaptateur d'ensemble de seringue pour une seringue
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WO2018136398A1 (fr) 2017-01-17 2018-07-26 Amgen Inc. Dispositifs d'injection et procédés d'utilisation et d'assemblage associés
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KR102651078B1 (ko) 2017-03-28 2024-03-22 암겐 인코포레이티드 플런저 로드 및 주사기 조립 시스템 및 방법
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JP7195276B2 (ja) 2017-06-22 2022-12-23 アムジエン・インコーポレーテツド デバイス起動による衝突／衝撃の低減
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