AP2593A - Crystalline pyridazine compound - Google Patents

Crystalline pyridazine compound

Info

Publication number
AP2593A
AP2593A AP2009005078A AP2009005078A AP2593A AP 2593 A AP2593 A AP 2593A AP 2009005078 A AP2009005078 A AP 2009005078A AP 2009005078 A AP2009005078 A AP 2009005078A AP 2593 A AP2593 A AP 2593A
Authority
AP
ARIPO
Prior art keywords
crystalline
pyridazine compound
pyridazine
compound
crystalline pyridazine
Prior art date
Application number
AP2009005078A
Other languages
English (en)
Other versions
AP2009005078A0 (en
Inventor
Eric D Dowdy
Kenneth M Kent
Norma J Tom
Original Assignee
Gilead Sciences Inc
Ku Leuven Res And Dev
Puerstinger Gerhard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39790369&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2593(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc, Ku Leuven Res And Dev, Puerstinger Gerhard filed Critical Gilead Sciences Inc
Publication of AP2009005078A0 publication Critical patent/AP2009005078A0/en
Application granted granted Critical
Publication of AP2593A publication Critical patent/AP2593A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AP2009005078A 2007-07-06 2008-07-03 Crystalline pyridazine compound AP2593A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95859507P 2007-07-06 2007-07-06
PCT/US2008/008259 WO2009009001A1 (en) 2007-07-06 2008-07-03 Crystalline pyridazine compound

Publications (2)

Publication Number Publication Date
AP2009005078A0 AP2009005078A0 (en) 2009-12-31
AP2593A true AP2593A (en) 2013-02-07

Family

ID=39790369

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2009005078A AP2593A (en) 2007-07-06 2008-07-03 Crystalline pyridazine compound

Country Status (19)

Country Link
US (2) US8106054B2 (es)
EP (1) EP2170881A1 (es)
JP (2) JP5366944B2 (es)
KR (1) KR101229528B1 (es)
CN (1) CN101778847B (es)
AP (1) AP2593A (es)
AR (1) AR066158A1 (es)
AU (1) AU2008275756B2 (es)
BR (1) BRPI0814801A2 (es)
CA (1) CA2691917C (es)
CO (1) CO6251293A2 (es)
EA (2) EA201270275A1 (es)
EC (1) ECSP109919A (es)
IL (1) IL202694A0 (es)
MX (1) MX2009013833A (es)
TW (1) TWI447116B (es)
UA (1) UA99466C2 (es)
WO (1) WO2009009001A1 (es)
ZA (1) ZA201000826B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
DK2161273T3 (en) 2003-12-22 2015-07-20 Leuven K U Res & Dev Imidazo [4,5-C] pyridine compounds and methods for antiviral therapy
PT1841765E (pt) * 2004-12-21 2009-05-14 Gilead Sciences Inc Anticorpos para mcp-1 humano
US7754720B2 (en) 2006-07-07 2010-07-13 Gilead Sciences, Inc. Pyridazine compound and use thereof
DK2094702T3 (en) 2006-12-14 2015-12-07 Gilead Sciences Inc viral inhibitors
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
MX2012007076A (es) 2009-12-18 2012-07-20 Boehringer Ingelheim Int Terapia combinada de hcv.
NZ603310A (en) 2010-05-21 2015-01-30 Gilead Sciences Inc Heterocyclic flaviviridae virus inhibitors
TW201306841A (zh) 2010-12-20 2013-02-16 Gilead Sciences Inc 治療ｃ型肝炎病毒（ｈｃｖ）之方法
US20120204871A1 (en) * 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
HRP20180237T4 (hr) 2011-09-16 2020-12-11 Gilead Pharmasset Llc Metode za liječenje hcv-a
EP2950786B1 (en) 2013-01-31 2019-11-27 Gilead Pharmasset LLC Combination formulation of two antiviral compounds
WO2016106050A1 (en) 2014-12-26 2016-06-30 Emory University N4-hydroxycytidine and derivatives and anti-viral uses related thereto
RU2020116571A (ru) 2017-12-07 2021-11-22 Эмори Юниверсити N4-гидроксицитидин и производные и связанные с этим противовирусные применения
CN114195812A (zh) * 2021-12-30 2022-03-18 大连联化化学有限公司 一种合成2,4-二三氟甲基苯硼酸的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063744A2 (en) * 2003-12-22 2005-07-14 K.U. Leuven Research & Development IMIDAZO[4,5-c]PYRIDINE COMPOUNDS AND METHODS OF ANTIVIRAL TREATMENT
WO2008005519A2 (en) * 2006-07-07 2008-01-10 Gilead Sciences, Inc. Novel pyridazine compound and use thereof

Family Cites Families (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2191978A (en) 1935-10-10 1940-02-27 Ig Farbenindustrie Ag Quaternary nitrogen compounds and process of preparing them
US2411662A (en) 1943-05-13 1946-11-26 Geigy Ag J R Imino-di-fatty acid amide
US2548863A (en) 1946-05-29 1951-04-17 Wyeth Corp Substituted glycinamides
US2516674A (en) 1948-10-29 1950-07-25 Wyeth Corp Substituted glycinamide
US3985891A (en) 1973-02-03 1976-10-12 Boehringer Ingelheim Gmbh 2-Phenyl-imidazo (4,5-b)pyridines and salts thereof
SU813921A1 (ru) 1979-10-26 1986-12-23 Институт физико-органической химии и углехимии АН УССР Стирильные производные имидазо(4,5- @ )пиридиний иодида,обладающие фунгицидной активностью
SU851940A1 (ru) 1980-03-20 1988-04-30 Институт физико-органической химии и углехимии АН УССР Четвертичные соли имидазо @ 4,5-с @ пиридини ,обладающие антимикробной и фунгистатической активностью
SU860463A1 (ru) 1980-04-09 1998-05-27 Институт физико-органической химии и углехимии АН Украинской ССР Производные 4-амино-1,3-диметилимидазо [4,5-с] пиридин-2-она, обладающие акарицидным действием
SU1048742A1 (ru) 1981-03-30 1986-12-23 Институт физико-органической химии и углехимии АН УССР 2,4-Дистирилпроизводные имидазо-(4,5- @ )пиридини ,обладающие бактериостатической и фунгистатической активностью
US4358387A (en) 1981-08-10 1982-11-09 Texaco Inc. Cylinder lubricating oil composition
US5137896A (en) 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
CA1183847A (en) 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives
FR2527608B1 (fr) 1982-05-28 1986-10-10 Sandoz Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments
US4692443A (en) 1983-10-17 1987-09-08 Eli Lilly And Company 3-bicyclicpyridinium-methyl cephalosporins
ZA847926B (en) 1983-10-17 1986-05-28 Lilly Co Eli 3-bicyclicpyridinium-methyl cephalosporins
GB8501542D0 (en) 1985-01-22 1985-02-20 Erba Farmitalia 4 5 6 7-tetrahydro-imidazo(4 5-clpyridine derivatives
GB8530602D0 (en) 1985-12-12 1986-01-22 Fujisawa Pharmaceutical Co Heterocyclic compounds
ES2052544T3 (es) 1986-02-03 1994-07-16 Janssen Pharmaceutica Nv Composiciones anti-histaminicas que contienen n-heterociclil-4-piperidinaminas.
US4804658A (en) 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions
NZ225447A (en) 1987-07-20 1991-12-23 Merck & Co Inc Piperazinyl derivatives of purine and purine isosteres and pharmaceutical compositions
US5057517A (en) 1987-07-20 1991-10-15 Merck & Co., Inc. Piperazinyl derivatives of purines and isosteres thereof as hypoglycemic agents
US5227384A (en) 1988-03-14 1993-07-13 G. D. Searle & Co. 5-substituted [4,5-c] imidazopyridines and pharmaceutical use thereof
US5302601A (en) 1988-03-14 1994-04-12 G. D. Searle & Co. 5-substituted imidazo[4,5-c]pyridines
US5019581A (en) 1988-03-14 1991-05-28 G. D. Searle & Co. 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US4914108A (en) 1988-03-14 1990-04-03 G. D. Searle & Co. 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US5332744A (en) 1989-05-30 1994-07-26 Merck & Co., Inc. Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists
US4988707A (en) 1989-09-13 1991-01-29 G. D. Searle & Co. Pharmacologically active phenylalkanoyl substituted imidazo (4,5-C) pyridines
US4990518A (en) 1989-09-13 1991-02-05 G. D. Searle & Co. Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines
FR2663332B1 (fr) 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5011832A (en) 1990-06-26 1991-04-30 Merck & Co., Inc. 2-biphenyl-carbapenem antibacterial agents
JPH04327587A (ja) 1991-04-26 1992-11-17 Asahi Chem Ind Co Ltd ６’−ｃ−アルキル−３−デアザネプラノシンａ誘導体、その製造法およびその用途
DE4122474A1 (de) 1991-07-06 1993-01-07 Basf Ag Fungizide mischung
GB9116056D0 (en) 1991-07-24 1991-09-11 British Bio Technology Compounds
US5587372A (en) 1991-12-12 1996-12-24 Roussel Uclaf Cephalosporins
GB9202792D0 (en) 1992-02-11 1992-03-25 British Bio Technology Compounds
DE4211474A1 (de) 1992-04-06 1993-10-07 Merck Patent Gmbh Imidazopyridine
US20030073159A1 (en) * 1992-05-11 2003-04-17 Human Genome Sciences, Inc. Human inhibitor of apoptosis gene 1
US5208242A (en) 1992-08-26 1993-05-04 G. D. Searle & Co. 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
DE4230464A1 (de) 1992-09-11 1994-03-17 Merck Patent Gmbh Imidazolderivate
DE4236026A1 (de) 1992-10-24 1994-04-28 Merck Patent Gmbh Imidazopyridine
JP3115455B2 (ja) 1992-12-18 2000-12-04 明治製菓株式会社 新規セファロスポリン誘導体
US5374638A (en) 1993-03-19 1994-12-20 Merck & Co., Inc. Six membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives used to treat asthma
DE4309969A1 (de) 1993-03-26 1994-09-29 Bayer Ag Substituierte heteroanellierte Imidazole
DE4318813A1 (de) 1993-06-07 1994-12-08 Merck Patent Gmbh Imidazopyridine
DE4324580A1 (de) 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5486525A (en) 1993-12-16 1996-01-23 Abbott Laboratories Platelet activating factor antagonists: imidazopyridine indoles
US5563143A (en) 1994-09-21 1996-10-08 Pfizer Inc. Catechol diether compounds as inhibitors of TNF release
US6506876B1 (en) 1994-10-11 2003-01-14 G.D. Searle & Co. LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use
US5585492A (en) 1994-10-11 1996-12-17 G. D. Searle & Co. LTA4 Hydrolase inhibitors
US5872136A (en) 1996-04-03 1999-02-16 Merck & Co., Inc. Arylheteroaryl inhibitors of farnesyl-protein transferase
US6063930A (en) 1996-04-03 2000-05-16 Merck & Co., Inc. Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US5854265A (en) 1996-04-03 1998-12-29 Merck & Co., Inc. Biheteroaryl inhibitors of farnesyl-protein transferase
US5859035A (en) 1996-04-03 1999-01-12 Merck & Co., Inc. Arylheteroaryl inhibitors of farnesyl-protein transferase
US6080870A (en) 1996-04-03 2000-06-27 Merck & Co., Inc. Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US5939557A (en) 1996-04-03 1999-08-17 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5883105A (en) 1996-04-03 1999-03-16 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5874452A (en) 1996-04-03 1999-02-23 Merck & Co., Inc. Biheteroaryl inhibitors of farnesyl-protein transferase
US5880140A (en) 1996-04-03 1999-03-09 Merck & Co., Inc. Biheteroaryl inhibitors of farnesyl-protein transferase
JP4375901B2 (ja) 1997-11-28 2009-12-02 大日本住友製薬株式会社 新規な複素環化合物
DE19845153A1 (de) 1998-10-01 2000-04-06 Merck Patent Gmbh Imidazo[4,5]-pyridin-4-on-derivate
DE19900471A1 (de) 1999-01-08 2000-07-13 Merck Patent Gmbh Imidazo[4,5c]-pyridin-4-on-derivate
US6767654B2 (en) 1999-01-08 2004-07-27 Chisso Corporation Organic electroluminescent device
CA2373073A1 (en) 1999-05-07 2000-11-16 Takeda Chemical Industries, Ltd. Cyclic compounds and uses thereof
US6844367B1 (en) 1999-09-17 2005-01-18 Millennium Pharmaceuticals, Inc. Benzamides and related inhibitors of factor Xa
CZ20013424A3 (cs) 1999-12-27 2002-02-13 Japan Tobacco Inc. Sloučeniny s fúzovanými kruhy a jejich pouľití jako léčiva
US6770666B2 (en) 1999-12-27 2004-08-03 Japan Tobacco Inc. Fused-ring compounds and use thereof as drugs
WO2001064642A2 (en) 2000-02-29 2001-09-07 Cor Therapeutics, Inc. Benzamides and related inhibitors of factor xa
EP1132381A1 (en) 2000-03-08 2001-09-12 Cermol S.A. Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them
US6448281B1 (en) 2000-07-06 2002-09-10 Boehringer Ingelheim (Canada) Ltd. Viral polymerase inhibitors
JP4331944B2 (ja) 2001-04-17 2009-09-16 大日本住友製薬株式会社 新規アデニン誘導体
AR035543A1 (es) 2001-06-26 2004-06-16 Japan Tobacco Inc Agente terapeutico para la hepatitis c que comprende un compuesto de anillo condensado, compuesto de anillo condensado, composicion farmaceutica que lo comprende, compuestos de benzimidazol, tiazol y bifenilo utiles como intermediarios para producir dichos compuestos, uso del compuesto de anillo con
US20030073836A1 (en) 2001-07-05 2003-04-17 Boehringer Ingelheim Pharma Kg Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions
US7294457B2 (en) 2001-08-07 2007-11-13 Boehringer Ingelheim (Canada) Ltd. Direct binding assay for identifying inhibitors of HCV polymerase
DE10140246A1 (de) 2001-08-09 2003-03-06 Forsch Pigmente Und Lacke E V Verfahren zur Behandlung von Oberflächen von Substraten
US20030134853A1 (en) 2001-09-26 2003-07-17 Priestley Eldon Scott Compounds useful for treating hepatitis C virus
CA2471566A1 (en) 2002-01-10 2003-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Combination of mtp inhibitors or apob-secretion inhibitors with fibrates for use as pharmaceuticals
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
CA2496249C (en) 2002-08-21 2012-01-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-[3-amino-piperidin-1-yl]-xanthines, the production thereof and the use of the same as medicaments
NZ538932A (en) 2002-08-29 2007-04-27 Boehringer Ingelheim Pharma 3-(sulfonamidoethyl)-indole derivatives for use as glucocorticoid mimetics in the treatment of inflammatory, allergic and proliferative disease
CN1744899A (zh) 2002-12-13 2006-03-08 史密丝克莱恩比彻姆公司 作为ccr5拮抗剂的哌啶衍生物
US7223785B2 (en) 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7098231B2 (en) 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
EP1590334B1 (en) 2003-01-30 2009-08-19 Boehringer Ingelheim Pharmaceuticals Inc. 2,4-diaminopyrimidine derivatives useful as inhibitors of pkc-theta
US7566707B2 (en) 2003-06-18 2009-07-28 Boehringer Ingelheim International Gmbh Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
RU2374230C2 (ru) 2003-11-05 2009-11-27 Ф.Хоффманн-Ля Рош Аг Фенильные производные в качестве ppar агонистов
CN101027303A (zh) 2004-07-27 2007-08-29 吉里德科学公司 咪唑并[4，5－d]嘧啶类、其应用和制备方法
CN101018843B (zh) 2004-09-13 2011-05-11 西巴特殊化学品控股有限公司 烷基氨基乙酰胺润滑添加剂
PT1841765E (pt) 2004-12-21 2009-05-14 Gilead Sciences Inc Anticorpos para mcp-1 humano
WO2007063744A1 (ja) 2005-11-30 2007-06-07 Fujifilm Corporation 平版刷版の後露光方法、後露光装置、露光装置、露光用器具、現像方法、及び現像装置
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063744A2 (en) * 2003-12-22 2005-07-14 K.U. Leuven Research & Development IMIDAZO[4,5-c]PYRIDINE COMPOUNDS AND METHODS OF ANTIVIRAL TREATMENT
WO2008005519A2 (en) * 2006-07-07 2008-01-10 Gilead Sciences, Inc. Novel pyridazine compound and use thereof

Also Published As

Publication number Publication date
IL202694A0 (en) 2010-06-30
CA2691917A1 (en) 2009-01-15
JP2013216695A (ja) 2013-10-24
EA200971080A1 (ru) 2010-08-30
TWI447116B (zh) 2014-08-01
EP2170881A1 (en) 2010-04-07
WO2009009001A1 (en) 2009-01-15
MX2009013833A (es) 2010-03-10
CA2691917C (en) 2013-12-03
UA99466C2 (en) 2012-08-27
EA018173B1 (ru) 2013-06-28
KR101229528B1 (ko) 2013-02-04
AU2008275756B2 (en) 2012-01-19
US8106054B2 (en) 2012-01-31
WO2009009001A9 (en) 2010-11-11
TW200918531A (en) 2009-05-01
AU2008275756A1 (en) 2009-01-15
US8569488B2 (en) 2013-10-29
AR066158A1 (es) 2009-07-29
US20090036460A1 (en) 2009-02-05
ZA201000826B (en) 2010-11-24
JP5366944B2 (ja) 2013-12-11
ECSP109919A (es) 2010-04-30
BRPI0814801A2 (pt) 2017-03-28
EA201270275A1 (ru) 2012-09-28
JP2010532757A (ja) 2010-10-14
US20120108601A1 (en) 2012-05-03
CN101778847B (zh) 2013-07-24
AP2009005078A0 (en) 2009-12-31
CN101778847A (zh) 2010-07-14
CO6251293A2 (es) 2011-02-21
KR20100044201A (ko) 2010-04-29

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