AP2987A - Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphate - Google Patents

Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphate

Info

Publication number: AP2987A
Authority: AP; ARIPO
Prior art keywords: hydroxymethyloxazolidin; methyltetrazol; pyridin; fluorophenyl; crystalline form
Prior art date: 2009-02-03

Application number

AP2011005835A

Other languages

English (en)

Other versions

AP2011005835A0 (en

Inventor

Robert J Duguid

Douglas Phillipson

Jacqueline A Ware

Original Assignee

Trius Therapeutics

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-02-03

Filing date

2010-02-03

Publication date

2014-09-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42289775&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2987(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-02-03 Application filed by Trius Therapeutics filed Critical Trius Therapeutics

2011-08-31 Publication of AP2011005835A0 publication Critical patent/AP2011005835A0/xx

2014-09-30 Application granted granted Critical

2014-09-30 Publication of AP2987A publication Critical patent/AP2987A/xx

Links

UAXDUQWXEJLTSR-UTONKHPSSA-N (5r)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one;phosphoric acid Chemical compound OP(O)(O)=O.CN1N=NC(C=2N=CC(=CC=2)C=2C(=CC(=CC=2)N2C(O[C@@H](CO)C2)=O)F)=N1 UAXDUQWXEJLTSR-UTONKHPSSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)

AP2011005835A 2009-02-03 2010-02-03 Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphate AP2987A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14940209P	2009-02-03	2009-02-03
PCT/US2010/023122 WO2010091131A1 (en)	2009-02-03	2010-02-03	Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate

Publications (2)

Publication Number	Publication Date
AP2011005835A0 AP2011005835A0 (en)	2011-08-31
AP2987A true AP2987A (en)	2014-09-30

Family

ID=42289775

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2011005835A AP2987A (en)	2009-02-03	2010-02-03	Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphate

Country Status (29)

Country	Link
US (6)	US8426389B2 (es)
EP (1)	EP2393808B1 (es)
JP (1)	JP5584705B2 (es)
KR (3)	KR101918678B1 (es)
CN (2)	CN107082790A (es)
AP (1)	AP2987A (es)
AU (1)	AU2010210627B2 (es)
BR (1)	BRPI1008829A2 (es)
CA (1)	CA2751392C (es)
CL (1)	CL2011001855A1 (es)
CO (1)	CO6620071A2 (es)
CR (1)	CR20110464A (es)
CU (1)	CU24089B1 (es)
DO (1)	DOP2011000251A (es)
EC (1)	ECSP11011285A (es)
ES (1)	ES2734724T3 (es)
IL (1)	IL214401B (es)
MA (1)	MA33092B1 (es)
MX (3)	MX384300B (es)
MY (1)	MY156354A (es)
NZ (3)	NZ620458A (es)
PE (1)	PE20120585A1 (es)
PH (1)	PH12014500092B1 (es)
RU (2)	RU2655928C1 (es)
SG (2)	SG10201500207QA (es)
TN (1)	TN2011000381A1 (es)
UA (1)	UA114068C2 (es)
WO (1)	WO2010091131A1 (es)
ZA (2)	ZA201106412B (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100854211B1 (ko) *	2003-12-18	2008-08-26	동아제약주식회사	신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2010042887A2 (en) *	2008-10-10	2010-04-15	Trius Therapeutics	Methods for preparing oxazolidinones and compositions containing them
BRPI1008829A2 (pt)	2009-02-03	2016-03-15	Trius Therapeutics	forma cristalina de dihidrogenofosfato de (r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofenil)-5-hidroximetil oxazolidin-2-ona
US8580767B2 (en) *	2009-05-28	2013-11-12	Trius Therapeutics, Inc.	Oxazolidinone containing dimer compounds, compositions and methods to make and use
WO2013059610A1 (en)	2011-10-20	2013-04-25	Trius Therapeutics, Inc.	Therapeutic combination of daptomycin and protein synthesis inhibitor antibiotic, and methods of use
WO2015054246A1 (en) *	2013-10-07	2015-04-16	Trius Therapeutics, Inc.	Methods of treating subjects with renal impairment using tedizolid
CN105229001B (zh) *	2014-04-18	2017-04-26	杭州普晒医药科技有限公司	一种噁唑烷酮类抗生素的晶型及制备方法、组合物和用途
WO2016009401A2 (en) *	2014-07-18	2016-01-21	Dr. Reddy's Laboratories Limited	Preparation of tedizolid phosphate
CN104327119A (zh) *	2014-10-17	2015-02-04	苏州明锐医药科技有限公司	磷酸泰地唑胺的制备方法
WO2016063246A1 (en) *	2014-10-22	2016-04-28	Sun Pharmaceutical Industries Limited	Crystalline form r of tedizolid phosphate
WO2016088100A1 (en) *	2014-12-05	2016-06-09	Sun Pharmaceutical Industries Limited	Processes for the preparation of tedizolid phosphate and its intermediates
WO2016088102A1 (en) *	2014-12-05	2016-06-09	Sun Pharmaceutical Industries Limited	Processes for the preparation of tedizolid phosphate and its intermediates
WO2016088101A1 (en) *	2014-12-05	2016-06-09	Sun Pharmaceutical Industries Limited	Processes for the preparation of tedizolid phosphate and its intermediates
CZ306245B6 (cs) *	2014-12-11	2016-10-26	Univerzita Karlova v Praze Farmaceutická fakulta v Hradci Králové	Substituovaný fenyltetrazol, jeho použití a farmaceutický přípravek ho obsahující
CN104558034A (zh) *	2015-01-21	2015-04-29	齐鲁制药有限公司	磷酸特地唑胺二钠盐的新晶型及其制备方法
CN105837634B (zh) *	2015-01-30	2020-09-04	上海创诺制药有限公司	一种泰地唑胺磷酸酯结晶体及其制备方法
CN104592218B (zh) *	2015-02-13	2015-11-04	江苏欧信医药化工有限公司	一种泰地唑胺的合成方法
CN106146485B (zh) *	2015-04-01	2021-04-30	上海迪赛诺化学制药有限公司	一种制备泰地唑胺的方法及其得到的泰地唑胺结晶体
CN106146558A (zh) *	2015-04-10	2016-11-23	博瑞生物医药（苏州）股份有限公司	新的噁唑烷酮类化合物及其制备方法
CN106317114B (zh) *	2015-07-02	2018-11-20	南京优科制药有限公司	一种磷酸特地唑胺的制备方法
CN105085570B (zh) *	2015-09-12	2017-11-28	山东罗欣药业集团股份有限公司	一种磷酸特地唑胺化合物及其制备方法
CN105287407B (zh) *	2015-11-24	2018-09-21	南京正大天晴制药有限公司	一种注射用磷酸特地唑胺
CN107121503B (zh) *	2017-03-14	2020-04-28	南京优科制药有限公司	一种磷酸特地唑胺及其有关物质的分析方法
CN108948079A (zh) *	2017-05-17	2018-12-07	上海奥博生物医药技术有限公司	一种特地唑胺二铵盐及晶型与其制备方法
WO2019118311A1 (en)	2017-12-13	2019-06-20	Merck Sharp & Dohme Corp.	Pharmaceutical compositions of tedizolid phosphate
US12109203B2 (en)	2018-07-25	2024-10-08	Zydus Lifesciences Limited	Substituted oxazolidinones for the treatment of mammalian infections
JP7805319B2 (ja)	2020-06-18	2026-01-23	アカゲラ・メディスンズ，インコーポレイテッド	オキサゾリジノン化合物、オキサゾリジノン化合物を含むリポソーム組成物、およびそれらの使用方法
CN112957332B (zh) *	2021-02-04	2023-04-25	海南通用康力制药有限公司	注射用磷酸特地唑胺及其质量标准
CN112957333B (zh) *	2021-02-05	2022-11-22	海南通用康力制药有限公司	注射用磷酸特地唑胺及其制备方法
CN113197874B (zh) *	2021-04-28	2023-05-26	北京福元医药股份有限公司	一种磷酸特地唑胺口服固体制剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005058886A1 (en) *	2003-12-18	2005-06-30	Dong-A Pharm.Co.,Ltd.	Novel oxazolidinone derivatives

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU80081A1 (fr)	1977-08-26	1979-05-15	Delalande Sa	Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
US4128654A (en)	1978-02-10	1978-12-05	E. I. Du Pont De Nemours And Company	5-Halomethyl-3-phenyl-2-oxazolidinones
US4340606A (en)	1980-10-23	1982-07-20	E. I. Du Pont De Nemours And Company	3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr)	1981-02-25	1982-08-27	Delalande Sa	Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
US4461773A (en)	1982-09-15	1984-07-24	E. I. Dupont De Nemours And Company	P-Oxooxazolidinylbenzene compounds as antibacterial agents
CA1320730C (en)	1987-10-16	1993-07-27	The Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US4948801A (en)	1988-07-29	1990-08-14	E. I. Du Pont De Nemours And Company	Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5254577A (en)	1988-07-29	1993-10-19	The Du Pont Merck Pharmaceutical Company	Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5144911A (en) *	1990-11-28	1992-09-08	Moore Cheri L	Component bed system for a pet
AU667198B2 (en)	1991-11-01	1996-03-14	Pharmacia & Upjohn Company	Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk)	1992-05-08	2003-07-01	Pharmacia & Upjohn Company	Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
JP3558088B2 (ja)	1992-12-08	2004-08-25	ファルマシア・アンド・アップジョン・カンパニー	トロポン−置換のフェニルオキサゾリジノン抗菌剤
US5688792A (en)	1994-08-16	1997-11-18	Pharmacia & Upjohn Company	Substituted oxazine and thiazine oxazolidinone antimicrobials
MY115155A (en)	1993-09-09	2003-04-30	Upjohn Co	Substituted oxazine and thiazine oxazolidinone antimicrobials.
JP3698724B2 (ja)	1993-11-22	2005-09-21	ファルマシア・アンド・アップジョン・カンパニー	置換−ヒドロキシアセチルピペラジンフェニルオキサゾリジノンのエステル
GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
US6413981B1 (en)	1999-08-12	2002-07-02	Ortho-Mcneil Pharamceutical, Inc.	Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
GB0009803D0 (en)	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
BR0111280A (pt)	2000-06-05	2003-06-10	Dong A Pharm Co Ltd	Novos derivados de oxazolidinona e um processo para a preparação dos mesmos
US20020115669A1 (en)	2000-08-31	2002-08-22	Wiedeman Paul E.	Oxazolidinone chemotherapeutic agents
YU52403A (sh)	2000-12-26	2006-03-03	Dr.Reddy's Research Foundation	Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže
WO2002081470A1 (en)	2001-04-07	2002-10-17	Astrazeneca Ab	Oxazolidinones containing a sulfonimid group as antibiotics
US6623140B2 (en)	2001-04-13	2003-09-23	Scott R. Watterson	Illumination device having multiple light sources
US6627646B2 (en) *	2001-07-17	2003-09-30	Sepracor Inc.	Norastemizole polymorphs
PT1427711E (pt)	2001-09-11	2005-11-30	Astrazeneca Ab	Derivados de oxazolidinona e/ou isoxazolina como agentes antibacterianos
JP2005519870A (ja)	2001-10-25	2005-07-07	アストラゼネカアクチボラグ	抗菌活性をもつアリール置換オキサゾリジノン類
NZ515881A (en)	2001-12-03	2004-09-24	New Zealand Dairy Board	Cheese flavour ingredient and method of its production
AR038536A1 (es)	2002-02-25	2005-01-19	Upjohn Co	N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
AU2003207340A1 (en)	2002-02-28	2003-09-09	Astrazeneca Ab	3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
NZ535591A (en)	2002-02-28	2006-07-28	Astrazeneca Ab	Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
JP2006508192A (ja)	2002-11-28	2006-03-09	アストラゼネカアクチボラグ	抗細菌薬としてのオキサゾリジノンおよび／またはイソオキサゾリン誘導体
WO2004048350A2 (en)	2002-11-28	2004-06-10	Astrazeneca Ab	Oxazolidinones as antibacterial agents
US7144911B2 (en)	2002-12-31	2006-12-05	Deciphera Pharmaceuticals Llc	Anti-inflammatory medicaments
US7202257B2 (en)	2003-12-24	2007-04-10	Deciphera Pharmaceuticals, Llc	Anti-inflammatory medicaments
TW200500360A (en)	2003-03-01	2005-01-01	Astrazeneca Ab	Hydroxymethyl compounds
GB0306358D0 (en)	2003-03-20	2003-04-23	Astrazeneca Ab	Chemical compounds
JP2007521283A (ja)	2003-07-02	2007-08-02	メルクアンドカンパニーインコーポレーテッド	シクロプロピル基で置換されたオキサゾリジノン系抗生物質およびその誘導体
EP1646629B1 (en)	2003-07-02	2010-06-23	Merck Sharp & Dohme Corp.	Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof
WO2005051933A1 (en)	2003-11-28	2005-06-09	Ranbaxy Laboratories Limited	An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby
NZ529860A (en)	2003-11-28	2006-10-27	Ovita Ltd	Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases
JP2007514782A (ja)	2003-12-17	2007-06-07	リブ−エックスファーマシューティカルズ，インコーポレイテッド	ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
US20070191336A1 (en)	2003-12-24	2007-08-16	Flynn Daniel L	Anti-inflammatory medicaments
MXPA06013540A (es)	2004-05-25	2007-01-26	Astrazeneca Ab	Derivados de 3-(4-(2 -dihidroisoxasol -3-ilpiridin-5-il) fenil)-5- triazol-1- ilmetiloxazolidin -2-ona como inhibidores de mao para el tratamiento de infecciones bacterianas.
GB0411596D0 (en)	2004-05-25	2004-06-30	Astrazeneca Ab	Chemical process
EP1753755A1 (en)	2004-05-25	2007-02-21	AstraZeneca AB	3- {4- (pyridin-3-yl) phenyl} -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents
US20080064689A1 (en)	2004-05-25	2008-03-13	Astrazeneca Ab	3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents
WO2005116022A1 (en)	2004-05-25	2005-12-08	Astrazeneca Ab	3- `4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents
EP1799677A1 (en)	2004-10-08	2007-06-27	Ranbaxy Laboratories Limited	Oxazolidinone derivatives as antimicrobials
US20090018123A1 (en)	2005-06-20	2009-01-15	Milind D Sindkhedkar	Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation
WO2007138381A2 (en)	2005-10-14	2007-12-06	Targanta Therapeutics Inc.	Phosphonated oxazolidinones and uses thereof for the prevention and treatment of bone and joint infections
JP5455906B2 (ja) *	2007-08-06	2014-03-26	ミクウルクファーマシューティカルズ，インコーポレイテッド	細菌感染症治療のための抗微生物性オルト−フルオロフェニルオキサゾリジノン
CN101220001A (zh) *	2008-01-25	2008-07-16	浙江博泰化工有限公司	一种利奈唑酮的合成方法
WO2010042887A2 (en)	2008-10-10	2010-04-15	Trius Therapeutics	Methods for preparing oxazolidinones and compositions containing them
BRPI1008829A2 (pt)	2009-02-03	2016-03-15	Trius Therapeutics	forma cristalina de dihidrogenofosfato de (r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofenil)-5-hidroximetil oxazolidin-2-ona
US8580767B2 (en)	2009-05-28	2013-11-12	Trius Therapeutics, Inc.	Oxazolidinone containing dimer compounds, compositions and methods to make and use

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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005058886A1 (en) *	2003-12-18	2005-06-30	Dong-A Pharm.Co.,Ltd.	Novel oxazolidinone derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Vera-Cabrera, Lucio, et al. *

Also Published As

Publication number	Publication date
MX2011008093A (es)	2011-11-29
IL214401A0 (en)	2011-09-27
CN102439006A (zh)	2012-05-02
WO2010091131A1 (en)	2010-08-12
CL2011001855A1 (es)	2011-11-11
PE20120585A1 (es)	2012-06-13
KR20170135984A (ko)	2017-12-08
PH12014500092A1 (en)	2014-12-01
IL214401B (en)	2021-03-25
US10442829B2 (en)	2019-10-15
KR101739923B1 (ko)	2017-05-25
NZ620458A (en)	2015-10-30
AU2010210627A1 (en)	2011-08-25
RU2655928C1 (ru)	2018-05-30
MX2020011773A (es)	2020-11-24
MA33092B1 (fr)	2012-03-01
NZ712289A (en)	2017-03-31
AP2011005835A0 (en)	2011-08-31
US20100227839A1 (en)	2010-09-09
US20130310343A1 (en)	2013-11-21
CU20110155A7 (es)	2012-02-15
CO6620071A2 (es)	2013-02-15
CR20110464A (es)	2016-07-20
PH12014500092B1 (en)	2014-12-01
US20180251482A1 (en)	2018-09-06
US9624250B2 (en)	2017-04-18
SG173497A1 (en)	2011-09-29
AU2010210627B2 (en)	2016-03-03
KR20170040371A (ko)	2017-04-12
NZ594408A (en)	2014-03-28
ECSP11011285A (es)	2011-10-31
US9988406B2 (en)	2018-06-05
CA2751392A1 (en)	2010-08-12
ZA201306536B (en)	2014-05-28
UA114068C2 (xx)	2017-04-25
US10065947B1 (en)	2018-09-04
DOP2011000251A (es)	2011-11-15
ES2734724T3 (es)	2019-12-11
KR101918678B1 (ko)	2018-11-14
ZA201106412B (en)	2013-11-27
US20180244704A1 (en)	2018-08-30
RU2011136537A (ru)	2013-03-10
US20170275315A1 (en)	2017-09-28
US20160176905A1 (en)	2016-06-23
EP2393808A1 (en)	2011-12-14
EP2393808B1 (en)	2019-05-08
CA2751392C (en)	2017-03-28
BRPI1008829A2 (pt)	2016-03-15
TN2011000381A1 (en)	2013-03-27
JP2012516894A (ja)	2012-07-26
JP5584705B2 (ja)	2014-09-03
CN107082790A (zh)	2017-08-22
CU24089B1 (es)	2015-04-29
US8426389B2 (en)	2013-04-23
MX384300B (es)	2025-03-14
SG10201500207QA (en)	2015-03-30
KR20110120311A (ko)	2011-11-03
MY156354A (en)	2016-02-15

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