AP9700918A0 - Benzoxazoles and pyridine derivatives useful in the treatment of the type II diabetes - Google Patents
Benzoxazoles and pyridine derivatives useful in the treatment of the type II diabetesInfo
- Publication number
- AP9700918A0 AP9700918A0 AP9700918A AP9700918A AP9700918A0 AP 9700918 A0 AP9700918 A0 AP 9700918A0 AP 9700918 A AP9700918 A AP 9700918A AP 9700918 A AP9700918 A AP 9700918A AP 9700918 A0 AP9700918 A0 AP 9700918A0
- Authority
- AP
- ARIPO
- Prior art keywords
- benzoxazoles
- diabetes
- treatment
- type
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
| GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
| GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
| PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP9700918A0 true AP9700918A0 (en) | 1997-01-31 |
| AP776A AP776A (en) | 1999-10-28 |
Family
ID=27267309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/1997/000918A AP776A (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type Ii diabetes. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0772605A1 (en) |
| AP (1) | AP776A (en) |
| BR (1) | BR9508468A (en) |
| CA (1) | CA2196079A1 (en) |
| CZ (1) | CZ25497A3 (en) |
| DZ (1) | DZ1916A1 (en) |
| FI (1) | FI970357L (en) |
| HU (1) | HUT76637A (en) |
| IL (3) | IL125525A (en) |
| MA (1) | MA23632A1 (en) |
| MX (1) | MX9700763A (en) |
| NO (1) | NO307827B1 (en) |
| OA (1) | OA10470A (en) |
| PL (1) | PL318766A1 (en) |
| SK (1) | SK12297A3 (en) |
| WO (2) | WO1996004261A1 (en) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
| RU2169141C2 (en) * | 1996-04-04 | 2001-06-20 | Санкио Компани Лимитед | Derivatives of phenylalkylcarboxylic acid and pharmaceutical composition based on thereof |
| US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
| US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
| PL339660A1 (en) | 1997-10-02 | 2001-01-02 | Sankyo Co | Derivatives of amidocarboxylic acids |
| BR9812772A (en) | 1997-10-27 | 2000-10-10 | Reddy Research Foundation | "unpublished tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them" |
| CA2307068C (en) | 1997-10-27 | 2007-04-10 | Dr. Reddy's Laboratories Limited | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
| EP1124807A1 (en) * | 1997-10-27 | 2001-08-22 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
| US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
| US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| JP2002507543A (en) * | 1998-05-27 | 2002-03-12 | ドクター・レディーズ・リサーチ・ファウンデーション | Bicyclic compound, method for producing the same, and pharmaceutical composition containing them |
| EE200100155A (en) | 1998-09-17 | 2002-08-15 | Bristol-Myers Squibb Company | A method of treating atherosclerosis using an a2 inhibitor and a combination thereof |
| US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
| WO2000023416A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| WO2000023445A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| EP1123269A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU6190199A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
| WO2000023425A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| EP1123297A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
| US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
| UA60386C2 (en) * | 1998-10-29 | 2003-10-15 | Reddys Laboratories Ltd | A process for preparation of 3-[4-[2-(phenoxazine-10-yl)methoxy]phenyl]propionic acid derivatives (variants) and intermediary compounds for preparation thereof |
| WO2000063189A1 (en) * | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Crystalline r- guanidines, arginine or (l) -arginine (2s) -2- ethoxy -3-{4- [2-(10h -phenoxazin -10-yl)ethoxy]phenyl}propanoate |
| US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
| US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
| EP1171431A1 (en) * | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Compounds, their preparation and use |
| JP2002542246A (en) | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
| HUP0200807A3 (en) * | 1999-04-20 | 2003-03-28 | Novo Nordisk As | Substituted propionic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
| US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| EP1175412A1 (en) | 1999-04-28 | 2002-01-30 | Dr. Reddy's Research Foundation | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents |
| WO2001016120A1 (en) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Biaryl-oxa(thia)zole derivatives and their use as ppars modulators |
| ES2449194T3 (en) * | 2000-01-19 | 2014-03-18 | Cadila Healthcare Limited | Compounds that have hypolipidemic and hypocholesterolemic activities, procedure for their preparation and pharmaceutical compositions containing them |
| US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
| PL357017A1 (en) * | 2000-01-28 | 2004-07-12 | Novo Nordisk A/S | Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity |
| US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
| WO2001087860A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
| AU2001263083A1 (en) | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4h-benzo(1,4)oxazin-3-ones |
| WO2001087861A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
| US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
| US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
| US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
| US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU2002351752A1 (en) | 2001-12-29 | 2003-07-30 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
| US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
| US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
| US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
| EP2154131A4 (en) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | G protein-coupled receptor inhibitor and pharmaceutical product |
| EP3009136A1 (en) | 2011-01-31 | 2016-04-20 | Cadila Healthcare Limited | Treatment for lipodystrophy |
| UA114360C2 (en) | 2013-04-22 | 2017-05-25 | Каділа Хелткере Лімітед | A novel composition for nonalcoholic fatty liver disease (nafld) |
| US20160107989A1 (en) | 2013-05-30 | 2016-04-21 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
| TW201513857A (en) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | Synergistic compositions |
| IN2013MU02470A (en) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
| IN2013MU02905A (en) | 2013-09-06 | 2015-07-03 | Cadila Healthcare Ltd | |
| WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
| EP3551180B1 (en) | 2016-12-09 | 2021-09-29 | Cadila Healthcare Limited | Treatment for primary biliary cholangitis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| SK695A3 (en) * | 1992-07-03 | 1995-07-11 | Smithkline Beecham Plc | Heterocyclic compounds method of their production and using |
-
1995
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en not_active Ceased
- 1995-06-07 BR BR9508468A patent/BR9508468A/en unknown
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/en active
- 1995-07-27 IL IL12552595A patent/IL125525A/en unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/en unknown
- 1995-07-27 MA MA23972A patent/MA23632A1/en unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/en unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/en unknown
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 MX MX9700763A patent/MX9700763A/en unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 SK SK122-97A patent/SK12297A3/en unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Ceased
- 1995-07-28 FI FI970357A patent/FI970357L/en unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 PL PL95318766A patent/PL318766A1/en unknown
-
1997
- 1997-01-28 NO NO970373A patent/NO307827B1/en not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI970357A0 (en) | 1997-01-28 |
| MA23632A1 (en) | 1996-04-01 |
| CA2196079A1 (en) | 1996-02-15 |
| OA10470A (en) | 2002-04-08 |
| NO970373D0 (en) | 1997-01-28 |
| HUT76637A (en) | 1997-10-28 |
| NO307827B1 (en) | 2000-06-05 |
| CZ25497A3 (en) | 1997-09-17 |
| SK12297A3 (en) | 1997-08-06 |
| PL318766A1 (en) | 1997-07-07 |
| DZ1916A1 (en) | 2002-02-17 |
| FI970357A7 (en) | 1997-03-26 |
| AP776A (en) | 1999-10-28 |
| IL114759A0 (en) | 1995-12-31 |
| IL114759A (en) | 1999-10-28 |
| WO1996004260A1 (en) | 1996-02-15 |
| WO1996004261A1 (en) | 1996-02-15 |
| NO970373L (en) | 1997-03-18 |
| EP0772605A1 (en) | 1997-05-14 |
| MX9700763A (en) | 1997-05-31 |
| FI970357L (en) | 1997-03-26 |
| BR9508468A (en) | 1997-11-25 |
| IL125525A0 (en) | 1999-03-12 |
| IL125525A (en) | 2000-02-29 |
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