AP9901696A0 - Composition comprising 5-(4-(2-(N-methyl-N-2-pyridyl)amino) ehtoxy benzyl)thiazolidine-2,4-dione - Google Patents

Composition comprising 5-(4-(2-(N-methyl-N-2-pyridyl)amino) ehtoxy benzyl)thiazolidine-2,4-dione

Info

Publication number: AP9901696A0
Authority: AP; ARIPO
Prior art keywords: ehtoxy; thiazolidine; dione; pyridyl; benzyl
Prior art date: 1997-06-05

Application number

AP9901696A

Other versions

AP1214A (en

Original Assignee

Smithkline Beecham Plc

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-05

Filing date

1998-06-02

Publication date

1999-12-31

1997-06-18 Priority claimed from GBGB9712851.6A external-priority patent/GB9712851D0/en

1998-06-02 Application filed by Smithkline Beecham Plc, Smithkline Beecham Corp filed Critical Smithkline Beecham Plc

1999-12-31 Publication of AP9901696A0 publication Critical patent/AP9901696A0/en

2003-10-08 Application granted granted Critical

2003-10-08 Publication of AP1214A publication Critical patent/AP1214A/en

Links

ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 title 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 title 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)

APAP/P/1999/001696A 1997-06-05 1998-06-02 Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino) ethoxy} benzyl} thiazolidine-2, 4-dione. AP1214A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9711683.4A GB9711683D0 (en)	1997-06-05	1997-06-05	Composition
GBGB9712851.6A GB9712851D0 (en)	1997-06-18	1997-06-18	Composition
PCT/EP1998/003478 WO1998055122A1 (en)	1997-06-05	1998-06-02	Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione

Publications (2)

Publication Number	Publication Date
AP9901696A0 true AP9901696A0 (en)	1999-12-31
AP1214A AP1214A (en)	2003-10-08

Family

ID=26311662

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
APAP/P/1999/001696A AP1214A (en)	1997-06-05	1998-06-02	Composition comprising 5-[4-[2-(n-methyl-n-2-pyridyl)amino) ethoxy} benzyl} thiazolidine-2, 4-dione.

Country Status (29)

Country	Link
EP (1)	EP0998284A1 (en)
JP (1)	JP2001521553A (en)
KR (1)	KR20010013410A (en)
CN (3)	CN1112926C (en)
AP (1)	AP1214A (en)
AR (2)	AR015120A1 (en)
AU (1)	AU8215098A (en)
BG (1)	BG104048A (en)
BR (1)	BR9810405A (en)
CA (2)	CA2292629C (en)
CO (1)	CO4940400A1 (en)
DZ (1)	DZ2510A1 (en)
EA (1)	EA002384B1 (en)
GB (1)	GB9711683D0 (en)
HU (1)	HUP0004070A3 (en)
ID (1)	ID24264A (en)
IL (1)	IL133074A0 (en)
MX (1)	MXPA99011322A (en)
NO (2)	NO995938L (en)
NZ (2)	NZ523725A (en)
OA (1)	OA11306A (en)
PE (1)	PE78899A1 (en)
PL (1)	PL337201A1 (en)
SK (1)	SK164899A3 (en)
TR (2)	TR200002790T2 (en)
TW (1)	TW570797B (en)
UY (1)	UY25032A1 (en)
WO (1)	WO1998055122A1 (en)
ZA (2)	ZA9811572B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7045519B2 (en)	1998-06-19	2006-05-16	Chiron Corporation	Inhibitors of glycogen synthase kinase 3
PL351684A1 (en) *	1999-04-23	2003-06-02	Smithkline Beecham Plc	Polymorph of 5−[4−[2− (n−methyl−n−( 2−pyridyl)amino) ethoxy]benzyl] thiazolidine−2,4−dione, maleic acid salt
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
AU765498B2 (en)	1999-04-23	2003-09-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021978D0 (en)	2000-09-07	2000-10-25	Smithkline Beecham Plc	Novel pharmaceutical
GB0127805D0 (en) *	2001-11-20	2002-01-09	Smithkline Beecham Plc	Pharmaceutical composition
GB0129871D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
AU2002350965A1 (en) *	2001-12-13	2003-06-23	Smithkline Beecham Plc	Toluenesulfonate hydrates of a thiazolidinedione derivative
GB0129876D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0130509D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
ES2294980T1 (en) *	2006-05-09	2008-04-16	Teva Pharmaceutical Industries Ltd.	ACID 2-N- (5 - ((4- (2- (METHYL-2-PYRIDINYLAMINE) ETHOXY) PHENYL) METHYL) -2,4-THIAZOLIDINDIONA) -BUTANODIOIC, PREPARATION PROCEDURES AND COMPOSITIONS WITH ROSIGLITAZONA MALEATE.
US7435741B2 (en)	2006-05-09	2008-10-14	Teva Pharmaceutical Industries, Ltd.	2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
WO2015008234A1 (en) *	2013-07-17	2015-01-22	Glenmark Pharmaceuticals S.A.	Bicyclic heterocyclic compounds as ror gamma modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE186724T1 (en) *	1987-09-04	1999-12-15	Beecham Group Plc	SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVES
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
JPH09512249A (en) *	1994-02-10	1997-12-09	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	Use of insulin sensitizer to treat kidney disease
CN1192683A (en) *	1995-08-10	1998-09-09	沃尼尔·朗伯公司	Method for reducing exogenous insulin dosage in patients with non-insulin-dependent diabetes mellitus
WO1997018811A1 (en) *	1995-11-17	1997-05-29	Warner-Lambert Company	A method of treating myotonic dystrophy
IL120443A (en) *	1996-03-18	2000-07-16	Sankyo Co	Use of an insulin sensitizer for the manufacture of a medicament for the treatment or prophylaxis of pancreatitis
PL331148A1 (en) *	1996-07-12	1999-06-21	Smithkline Beecham Plc	Novel method of treating the leptin immunity

1997
- 1997-06-05 GB GBGB9711683.4A patent/GB9711683D0/en active Pending
1998
- 1998-06-02 ID IDW991520A patent/ID24264A/en unknown
- 1998-06-02 IL IL13307498A patent/IL133074A0/en unknown
- 1998-06-02 JP JP50158799A patent/JP2001521553A/en not_active Ceased
- 1998-06-02 TR TR2000/02790T patent/TR200002790T2/en unknown
- 1998-06-02 AU AU82150/98A patent/AU8215098A/en not_active Abandoned
- 1998-06-02 WO PCT/EP1998/003478 patent/WO1998055122A1/en not_active Ceased
- 1998-06-02 CN CN98805686A patent/CN1112926C/en not_active Expired - Lifetime
- 1998-06-02 TR TR1999/02963T patent/TR199902963T2/en unknown
- 1998-06-02 NZ NZ523725A patent/NZ523725A/en unknown
- 1998-06-02 MX MXPA99011322A patent/MXPA99011322A/en unknown
- 1998-06-02 KR KR19997011411A patent/KR20010013410A/en not_active Ceased
- 1998-06-02 EP EP98932144A patent/EP0998284A1/en not_active Withdrawn
- 1998-06-02 BR BR9810405-5A patent/BR9810405A/en not_active IP Right Cessation
- 1998-06-02 CN CNA2003101199090A patent/CN1526391A/en active Pending
- 1998-06-02 CA CA002292629A patent/CA2292629C/en not_active Expired - Fee Related
- 1998-06-02 HU HU0004070A patent/HUP0004070A3/en unknown
- 1998-06-02 AP APAP/P/1999/001696A patent/AP1214A/en active
- 1998-06-02 CA CA002333352A patent/CA2333352A1/en not_active Abandoned
- 1998-06-02 PL PL98337201A patent/PL337201A1/en unknown
- 1998-06-02 SK SK1648-99A patent/SK164899A3/en unknown
- 1998-06-02 EA EA199901116A patent/EA002384B1/en not_active IP Right Cessation
- 1998-06-03 DZ DZ980120A patent/DZ2510A1/en active
- 1998-06-04 AR ARP980102650A patent/AR015120A1/en not_active Application Discontinuation
- 1998-06-04 ZA ZA9811572A patent/ZA9811572B/en unknown
- 1998-06-04 AR ARP980102649A patent/AR008198A1/en not_active Application Discontinuation
- 1998-06-04 UY UY25032A patent/UY25032A1/en not_active IP Right Cessation
- 1998-06-04 ZA ZA9804826A patent/ZA984826B/en unknown
- 1998-06-04 CO CO98031614A patent/CO4940400A1/en unknown
- 1998-06-05 PE PE1998000466A patent/PE78899A1/en not_active Application Discontinuation
- 1998-10-23 TW TW087117536A patent/TW570797B/en not_active IP Right Cessation
1999
- 1999-12-02 OA OA9900267A patent/OA11306A/en unknown
- 1999-12-03 NO NO995938A patent/NO995938L/en not_active Application Discontinuation
- 1999-12-27 BG BG104048A patent/BG104048A/en unknown
2001
- 2001-09-03 NZ NZ513922A patent/NZ513922A/en unknown
2002
- 2002-11-05 CN CN02149972A patent/CN1430959A/en active Pending
2004
- 2004-02-20 NO NO20040738A patent/NO20040738L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
CO4940400A1 (en)	2000-07-24
TW570797B (en)	2004-01-11
AR008198A1 (en)	1999-12-29
DZ2510A1 (en)	2003-01-25
TR199902963T2 (en)	2000-02-21
KR20010013410A (en)	2001-02-26
NZ513922A (en)	2001-09-28
CN1112926C (en)	2003-07-02
CN1526391A (en)	2004-09-08
GB9711683D0 (en)	1997-08-06
CA2292629C (en)	2004-01-06
ZA984826B (en)	1999-08-03
WO1998055122A1 (en)	1998-12-10
CA2292629A1 (en)	1998-12-10
NO995938L (en)	2000-02-02
SK164899A3 (en)	2000-11-07
NO995938D0 (en)	1999-12-03
BG104048A (en)	2000-07-31
HUP0004070A3 (en)	2002-03-28
CA2333352A1 (en)	1998-12-10
TR200002790T2 (en)	2001-11-21
MXPA99011322A (en)	2004-12-02
NZ523725A (en)	2004-09-24
BR9810405A (en)	2000-08-29
ZA9811572B (en)	1999-07-22
CN1430959A (en)	2003-07-23
EP0998284A1 (en)	2000-05-10
ID24264A (en)	2000-07-13
AU8215098A (en)	1998-12-21
PE78899A1 (en)	1999-10-22
NO20040738L (en)	2000-02-02
OA11306A (en)	2003-10-22
IL133074A0 (en)	2001-03-19
PL337201A1 (en)	2000-08-14
AR015120A1 (en)	2001-04-18
CN1259050A (en)	2000-07-05
JP2001521553A (en)	2001-11-06
HUP0004070A2 (en)	2002-02-28
AP1214A (en)	2003-10-08
EA199901116A1 (en)	2000-06-26
UY25032A1 (en)	1998-11-26
EA002384B1 (en)	2002-04-25

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