AR010102A1 - VACUNA VIVA RECOMBINANTE AVIARIA QUE COMPRENDE CoMO VECTOR UN VIRUS ILTV QUE COMPRENDE Y EXPRESA AL MENOS UNA SECUENCIA NUCLEOTíDICAHETERoLOGA - Google Patents

VACUNA VIVA RECOMBINANTE AVIARIA QUE COMPRENDE CoMO VECTOR UN VIRUS ILTV QUE COMPRENDE Y EXPRESA AL MENOS UNA SECUENCIA NUCLEOTíDICAHETERoLOGA

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Publication number
AR010102A1
AR010102A1 ARP980100145A ARP980100145A AR010102A1 AR 010102 A1 AR010102 A1 AR 010102A1 AR P980100145 A ARP980100145 A AR P980100145A AR P980100145 A ARP980100145 A AR P980100145A AR 010102 A1 AR010102 A1 AR 010102A1
Authority
AR
Argentina
Prior art keywords
iltv
understands
requested
expresses
vector
Prior art date
Application number
ARP980100145A
Other languages
English (en)
Original Assignee
Merial Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Llc filed Critical Merial Llc
Publication of AR010102A1 publication Critical patent/AR010102A1/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16041Use of virus, viral particle or viral elements as a vector
    • C12N2710/16043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/816Viral vaccine for avian species, e.g. poultry or other birds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La vacuna viva recombinante aviaria comprende como vector un virus ILTV queexpresa al menos una secuencia nucleotídica heterologa, estando insertada esta snucleotídica en el sitio de insercion formado por el intergen situado entre los los cuadros abiertos de lectura D y E del ILTV y que, en una cepa de ILTV particdefinido entre los nucleotidos 3873 y 4260 en SEQ ID NO:1. La secuencia nucleotíestar bajo el control de un promotor eucatiotido fuerte, tal como el promotor CMprovenir de los virus dela enfermedad de Newcastle, de la enfermedad de Marek, enfermedad de Gumboro, de la bronquitis infecciosa, de la anemia del pollo, de lneumovirosis del pollo. También se propone una formula de vacuna multivalente qucomprende al menos dos vacunas vivas segun la invencion, y el virus ILTV así recDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTE DATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTE DATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTE DATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTEDATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTE DATOS DEL DISQUETTE PRESENTADO POR EL SOLICITANTE
ARP980100145A 1997-01-31 1998-01-13 VACUNA VIVA RECOMBINANTE AVIARIA QUE COMPRENDE CoMO VECTOR UN VIRUS ILTV QUE COMPRENDE Y EXPRESA AL MENOS UNA SECUENCIA NUCLEOTíDICAHETERoLOGA AR010102A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9701317A FR2758986B1 (fr) 1997-01-31 1997-01-31 Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire

Publications (1)

Publication Number Publication Date
AR010102A1 true AR010102A1 (es) 2000-05-17

Family

ID=9503369

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980100145A AR010102A1 (es) 1997-01-31 1998-01-13 VACUNA VIVA RECOMBINANTE AVIARIA QUE COMPRENDE CoMO VECTOR UN VIRUS ILTV QUE COMPRENDE Y EXPRESA AL MENOS UNA SECUENCIA NUCLEOTíDICAHETERoLOGA

Country Status (10)

Country Link
US (1) US6306400B1 (es)
EP (1) EP0968297B1 (es)
JP (1) JP2001511142A (es)
AR (1) AR010102A1 (es)
AU (1) AU735265B2 (es)
CO (1) CO4650230A1 (es)
FR (1) FR2758986B1 (es)
MA (1) MA24458A1 (es)
TN (1) TNSN98015A1 (es)
WO (1) WO1998033928A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632664B1 (en) 1997-10-03 2003-10-14 Nippon Zeon Co., Ltd. Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same
AR031405A1 (es) * 2000-11-21 2003-09-24 Wyeth Corp Metodos y vacunas para conferir proteccion in ovo contra la rinotraqueitis del pavo
EP1241177A1 (en) * 2001-03-15 2002-09-18 Akzo Nobel N.V. Recombinant infectious laryngotracheitis virus vaccine
EP2390352A1 (en) 2003-03-18 2011-11-30 Quantum Genetics Ireland Limited Systems and methods for improving protein and milk production of dairy herds
US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
WO2005027829A2 (en) * 2003-09-03 2005-03-31 Intralytix, Inc. Method for vaccination of poultry by bacteriophage lysate
US20050214316A1 (en) 2003-11-13 2005-09-29 Brown Thomas P Methods of characterizing infectious bursal disease virus
US20050202484A1 (en) 2004-02-19 2005-09-15 The Governors Of The University Of Alberta Leptin promoter polymorphisms and uses thereof
HRP20100314T1 (hr) 2005-04-25 2010-08-31 Merial Ltd. Cjepivo protiv nipah virusa
US20080241184A1 (en) 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
JP2009515529A (ja) 2005-11-14 2009-04-16 メリアル リミテッド 腎不全のための遺伝子療法
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
US7794714B2 (en) * 2008-03-14 2010-09-14 The United States Of America As Represented By The Secretary Of Agriculture Newcastle disease virus monoclonal antibodies
MX2011010406A (es) 2009-04-03 2012-01-20 Merial Ltd Vacunas aviares vectorizadas con el virus de la emfermedad de newcastle.
WO2011090708A2 (en) 2009-12-28 2011-07-28 Merial Limited Recombinant ndv antigen and uses thereof
EP3156070A3 (en) 2010-08-31 2017-06-14 Merial Inc. Newcastle disease virus vectored herpesvirus vaccines
WO2012090073A2 (en) 2010-12-30 2012-07-05 The Netherlands Cancer Institute Methods and compositions for predicting chemotherapy sensitivity
AU2012240240A1 (en) 2011-04-04 2013-05-09 Netherlands Cancer Institute Methods and compositions for predicting resistance to anticancer treatment with protein kinase inhibitors
WO2012138789A2 (en) 2011-04-04 2012-10-11 Netherlands Cancer Institute Methods and compositions for predicting resistance to anticancer treatment
WO2012145577A1 (en) 2011-04-20 2012-10-26 Merial Limited Adjuvanted rabies vaccine with improved viscosity profile
EP2701736A1 (en) 2011-04-25 2014-03-05 Advanced Bioscience Laboratories, Inc. Truncated hiv envelope proteins (env), methods and compositions related thereto
CA2837375C (en) 2011-06-01 2019-07-16 Merial Limited Needle-free administration of prrsv vaccines
HUE035774T2 (en) 2011-08-12 2018-05-28 Merial Inc Biological substances, in particular vaccines, preserved by vacuum
WO2013093629A2 (en) 2011-12-20 2013-06-27 Netherlands Cancer Institute Modular vaccines, methods and compositions related thereto
WO2013138776A1 (en) 2012-03-16 2013-09-19 Merial Limited Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
WO2014164697A1 (en) 2013-03-12 2014-10-09 Merial Limited Reverse genetics schmallenberg virus vaccine compositions, and methods of use thereof
CN104164408B (zh) * 2013-05-15 2016-12-28 普莱柯生物工程股份有限公司 抗鸡新城疫、传染性支气管炎和禽流感疫苗组合物及制备
US10010499B2 (en) 2014-11-03 2018-07-03 Merial Inc. Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
CA2990643C (en) 2015-06-23 2023-10-17 Merial, Inc. Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof
KR102780119B1 (ko) 2016-12-14 2025-03-12 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 조류 병원체의 다중 항원을 발현하는 재조합 hvt 벡터 및 그를 포함하는 백신

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003554A1 (en) * 1990-08-24 1992-03-05 Arthur Webster Pty. Ltd. Infectious laryngotracheitis virus vaccine
WO1996000791A1 (en) * 1994-06-30 1996-01-11 The Board Of Trustees Of The University Of Illinois Recombinant infectious laryngotracheitis virus and vaccine
FR2728795B1 (fr) * 1994-12-30 1997-03-21 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur un virus herpes aviaire

Also Published As

Publication number Publication date
AU735265B2 (en) 2001-07-05
FR2758986B1 (fr) 1999-04-30
WO1998033928A1 (fr) 1998-08-06
EP0968297B1 (fr) 2005-03-23
AU6217798A (en) 1998-08-25
US6306400B1 (en) 2001-10-23
CO4650230A1 (es) 1998-09-03
JP2001511142A (ja) 2001-08-07
TNSN98015A1 (fr) 2005-03-15
MA24458A1 (fr) 1998-10-01
EP0968297A1 (fr) 2000-01-05
FR2758986A1 (fr) 1998-08-07

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