AR017430A1 - Un hidrato de la sal del acido maleico de la 5[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona, un proceso para su preparacion,composicion farmaceutica que lo contiene y uso del mismo para la fabricacion de un medicamento - Google Patents

Un hidrato de la sal del acido maleico de la 5[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona, un proceso para su preparacion,composicion farmaceutica que lo contiene y uso del mismo para la fabricacion de un medicamento

Info

Publication number: AR017430A1
Authority: AR; Argentina
Prior art keywords: amino; methyl; manufacture; preparation; maleic acid
Prior art date: 1997-12-16

Application number

ARP980106365A

Other languages

English (en)

Spanish (es)

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-16

Filing date

1998-12-15

Publication date

2001-09-05

1998-12-15 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2001-09-05 Publication of AR017430A1 publication Critical patent/AR017430A1/es

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
-1 AMINO Chemical class 0.000 title 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
230000036571 hydration Effects 0.000 title 1
238000006703 hydration reaction Methods 0.000 title 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 title 1
239000011976 maleic acid Substances 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
238000000634 powder X-ray diffraction Methods 0.000 abstract 2
ZGRMKPSQTQQYNY-UHFFFAOYSA-N 3-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CN1C(=O)CSC1=O ZGRMKPSQTQQYNY-UHFFFAOYSA-N 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000002329 infrared spectrum Methods 0.000 abstract 1
150000002688 maleic acid derivatives Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ARP980106365A 1997-12-16 1998-12-15 Un hidrato de la sal del acido maleico de la 5[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona, un proceso para su preparacion,composicion farmaceutica que lo contiene y uso del mismo para la fabricacion de un medicamento AR017430A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9726568.0A GB9726568D0 (en)	1997-12-16	1997-12-16	Novel pharmaceutical

Publications (1)

Publication Number	Publication Date
AR017430A1 true AR017430A1 (es)	2001-09-05

Family

ID=10823694

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ARP980106369A AR017213A1 (es)	1997-12-16	1998-12-15	Un proceso para preparar un hidrato de la sal del acido maleico de la 5-[4-[2-(n-metil-n-(2-piridil)amino)-etoxi]bencil]tiazolidin-2,4-diona
ARP980106365A AR017430A1 (es)	1997-12-16	1998-12-15	Un hidrato de la sal del acido maleico de la 5[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona, un proceso para su preparacion,composicion farmaceutica que lo contiene y uso del mismo para la fabricacion de un medicamento

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ARP980106369A AR017213A1 (es)	1997-12-16	1998-12-15	Un proceso para preparar un hidrato de la sal del acido maleico de la 5-[4-[2-(n-metil-n-(2-piridil)amino)-etoxi]bencil]tiazolidin-2,4-diona

Country Status (37)

Country	Link
US (2)	US7045633B2 (2)
EP (1)	EP1045847A1 (2)
JP (1)	JP2002508372A (2)
KR (1)	KR100549143B1 (2)
CN (3)	CN101412714A (2)
AP (1)	AP1441A (2)
AR (2)	AR017213A1 (2)
AU (1)	AU2272399A (2)
BG (1)	BG64905B1 (2)
BR (1)	BR9813604A (2)
CA (1)	CA2314965A1 (2)
CO (1)	CO4990927A1 (2)
CZ (1)	CZ299970B6 (2)
DZ (1)	DZ2680A1 (2)
EA (1)	EA002355B1 (2)
EG (2)	EG23694A (2)
GB (1)	GB9726568D0 (2)
HR (1)	HRP20000405A2 (2)
HU (1)	HUP0100500A3 (2)
ID (1)	ID24744A (2)
IL (1)	IL136381A (2)
IN (1)	IN190821B (2)
MA (1)	MA26582A1 (2)
MY (1)	MY135770A (2)
NO (1)	NO317253B1 (2)
NZ (1)	NZ504704A (2)
OA (1)	OA11634A (2)
PE (1)	PE20000057A1 (2)
PL (1)	PL341147A1 (2)
RS (1)	RS50079B (2)
SK (1)	SK286197B6 (2)
TR (2)	TR200001798T2 (2)
TW (1)	TW467913B (2)
UA (1)	UA63980C2 (2)
UY (2)	UY25310A1 (2)
WO (1)	WO1999031094A1 (2)
ZA (1)	ZA9811505B (2)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9909041D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
AU765498B2 (en) *	1999-04-23	2003-09-18	Smithkline Beecham Plc	Novel pharmaceutical
HK1045152A1 (zh) *	1999-04-23	2002-11-15	Smithkline Beecham Plc	噻唑烷二酮衍生物及其用作抗糖尿病藥的應用
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
GB0014005D0 (en) *	2000-06-08	2000-08-02	Smithkline Beecham Plc	Novel pharmaceutical
GB0021784D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021978D0 (en) *	2000-09-07	2000-10-25	Smithkline Beecham Plc	Novel pharmaceutical
AU2002350965A1 (en) *	2001-12-13	2003-06-23	Smithkline Beecham Plc	Toluenesulfonate hydrates of a thiazolidinedione derivative
GB0129876D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
AU2002352391A1 (en) *	2001-12-13	2003-06-23	Smithkline Beecham Plc	A 5(-4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl)thiazolidine-2,4-dione (i) 10-camphorsulphonic acid salt and use against diabetes mellitus
WO2003053962A1 (en) *	2001-12-20	2003-07-03	Smithkline Beecham Plc	5- (4- (2- (n-methyl-n- (2-pyridyl) amino) ethoxy) benzyl) thiazolidine-2, 4-dione malic acid salt and use against diabetes mellitus
GB0130511D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB2405403A (en) *	2003-08-29	2005-03-02	Cipla Ltd	Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
ITMI20041537A1 (it) *	2004-07-28	2004-10-28	Chemi Spa	Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) *	2005-05-24	2007-09-26	Zentiva, A. S.	Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
EP2184055A1 (en)	2008-11-07	2010-05-12	LEK Pharmaceuticals d.d.	Process for preparing solid dosage forms of rosiglitazone maleate

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR240698A1 (es) *	1985-01-19	1990-09-28	Takeda Chemical Industries Ltd	Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
US4812570A (en) *	1986-07-24	1989-03-14	Takeda Chemical Industries, Ltd.	Method for producing thiazolidinedione derivatives
ATE186724T1 (de)	1987-09-04	1999-12-15	Beecham Group Plc	Substituierte thiazolidindionderivate
GB8820389D0 (en) *	1988-08-26	1988-09-28	Beecham Group Plc	Novel compounds
GB9124513D0 (en)	1991-11-19	1992-01-08	Smithkline Beecham Plc	Novel process
EP0656900A4 (en)	1992-08-28	1995-09-06	Merck & Co Inc	CATIONIC 2-HETEROARYLPHENYL-CARBAPENEM DERIVATIVES AS AN ANTIBACTERIAL AGENT.
US5741803A (en)	1992-09-05	1998-04-21	Smithkline Beecham Plc	Substituted thiazolidinedionle derivatives
GB9218830D0 (en)	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
TW245716B (2) *	1992-12-28	1995-04-21	Takeda Pharm Industry Co
DE4404198A1 (de)	1994-02-10	1995-08-17	Henkel Kgaa	2-Fluor-6-nitroaniline
US6664278B2 (en) *	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726563D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US20020137940A1 (en)	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726566D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
CZ432299A3 (cs) *	1998-06-02	2000-08-16	Smithkline Beecham Plc	Kompozice obsahující 5-[4-[2-(N-methyl-N-(2- pyridyI)amino)ethoxy]benzyl]thiazolidin-2,4-dion
AU765498B2 (en)	1999-04-23	2003-09-18	Smithkline Beecham Plc	Novel pharmaceutical
HK1045152A1 (zh)	1999-04-23	2002-11-15	Smithkline Beecham Plc	噻唑烷二酮衍生物及其用作抗糖尿病藥的應用
PL351684A1 (en)	1999-04-23	2003-06-02	Smithkline Beecham Plc	Polymorph of 5−[4−[2− (n−methyl−n−( 2−pyridyl)amino) ethoxy]benzyl] thiazolidine−2,4−dione, maleic acid salt

1997
- 1997-12-16 GB GBGB9726568.0A patent/GB9726568D0/en not_active Ceased
1998
- 1998-12-14 CZ CZ20002205A patent/CZ299970B6/cs not_active IP Right Cessation
- 1998-12-14 JP JP2000539018A patent/JP2002508372A/ja not_active Withdrawn
- 1998-12-14 CN CNA2008100930575A patent/CN101412714A/zh active Pending
- 1998-12-14 UA UA2000063484A patent/UA63980C2/uk unknown
- 1998-12-14 ID IDW20001126A patent/ID24744A/id unknown
- 1998-12-14 TR TR2000/01798T patent/TR200001798T2/xx unknown
- 1998-12-14 BR BR9813604-6A patent/BR9813604A/pt not_active Application Discontinuation
- 1998-12-14 WO PCT/EP1998/008154 patent/WO1999031094A1/en not_active Ceased
- 1998-12-14 EP EP98966321A patent/EP1045847A1/en not_active Ceased
- 1998-12-14 MA MA25392A patent/MA26582A1/fr unknown
- 1998-12-14 RS YUP-362/00A patent/RS50079B/sr unknown
- 1998-12-14 NZ NZ504704A patent/NZ504704A/xx unknown
- 1998-12-14 KR KR1020007006517A patent/KR100549143B1/ko not_active Expired - Fee Related
- 1998-12-14 PL PL98341147A patent/PL341147A1/xx not_active Application Discontinuation
- 1998-12-14 OA OA1200000179A patent/OA11634A/en unknown
- 1998-12-14 HU HU0100500A patent/HUP0100500A3/hu unknown
- 1998-12-14 CA CA002314965A patent/CA2314965A1/en not_active Abandoned
- 1998-12-14 IL IL13638198A patent/IL136381A/xx unknown
- 1998-12-14 CN CN98812092A patent/CN1281454A/zh active Pending
- 1998-12-14 EA EA200000655A patent/EA002355B1/ru not_active IP Right Cessation
- 1998-12-14 AP APAP/P/2000/001830A patent/AP1441A/en active
- 1998-12-14 CN CNA2008100930560A patent/CN101412713A/zh active Pending
- 1998-12-14 AU AU22723/99A patent/AU2272399A/en not_active Abandoned
- 1998-12-14 SK SK910-2000A patent/SK286197B6/sk not_active IP Right Cessation
- 1998-12-14 HR HR20000405A patent/HRP20000405A2/hr not_active Application Discontinuation
- 1998-12-15 EG EG155098A patent/EG23694A/xx active
- 1998-12-15 AR ARP980106369A patent/AR017213A1/es not_active Application Discontinuation
- 1998-12-15 MY MYPI98005675A patent/MY135770A/en unknown
- 1998-12-15 UY UY25310A patent/UY25310A1/es not_active IP Right Cessation
- 1998-12-15 DZ DZ980290A patent/DZ2680A1/xx active
- 1998-12-15 UY UY25305A patent/UY25305A1/es not_active IP Right Cessation
- 1998-12-15 ZA ZA9811505A patent/ZA9811505B/xx unknown
- 1998-12-15 EG EG155498A patent/EG21417A/xx active
- 1998-12-15 AR ARP980106365A patent/AR017430A1/es not_active Application Discontinuation
- 1998-12-16 TR TR1998/02626A patent/TR199802626A2/xx unknown
- 1998-12-16 PE PE1998001232A patent/PE20000057A1/es not_active Application Discontinuation
- 1998-12-16 IN IN3770DE1998 patent/IN190821B/en unknown
- 1998-12-16 TW TW087121122A patent/TW467913B/zh not_active IP Right Cessation
- 1998-12-16 CO CO98074830A patent/CO4990927A1/es unknown
2000
- 2000-06-15 NO NO20003068A patent/NO317253B1/no not_active IP Right Cessation
- 2000-07-11 BG BG104595A patent/BG64905B1/bg unknown
2003
- 2003-10-24 US US10/692,544 patent/US7045633B2/en not_active Expired - Fee Related
2006
- 2006-03-16 US US11/377,470 patent/US20060189659A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EA200000655A1 (ru)	2000-12-25
EA002355B1 (ru)	2002-04-25
AU2272399A (en)	1999-07-05
CZ20002205A3 (cs)	2000-11-15
CZ299970B6 (cs)	2009-01-07
TW467913B (en)	2001-12-11
AP2000001830A0 (en)	2000-06-30
PL341147A1 (en)	2001-03-26
AR017213A1 (es)	2001-08-22
RS50079B (sr)	2009-01-22
KR100549143B1 (ko)	2006-02-03
PE20000057A1 (es)	2000-03-09
UA63980C2 (en)	2004-02-16
TR199802626A3 (tr)	1999-10-21
CA2314965A1 (en)	1999-06-24
MA26582A1 (fr)	2004-12-20
SK9102000A3 (en)	2001-01-18
BR9813604A (pt)	2000-10-10
NZ504704A (en)	2003-03-28
IL136381A0 (en)	2001-06-14
EG23694A (en)	2007-05-15
NO317253B1 (no)	2004-09-27
JP2002508372A (ja)	2002-03-19
IN190821B (2)	2003-08-23
HRP20000405A2 (en)	2000-12-31
HUP0100500A2 (hu)	2002-05-29
TR200001798T2 (tr)	2000-11-21
BG104595A (en)	2001-02-28
UY25305A1 (es)	2000-12-29
IL136381A (en)	2003-09-17
BG64905B1 (bg)	2006-08-31
EP1045847A1 (en)	2000-10-25
WO1999031094A1 (en)	1999-06-24
YU36200A (sh)	2003-12-31
NO20003068D0 (no)	2000-06-15
ID24744A (id)	2000-08-03
TR199802626A2 (xx)	1999-10-21
KR20010033142A (ko)	2001-04-25
CN1281454A (zh)	2001-01-24
CN101412713A (zh)	2009-04-22
US20060189659A1 (en)	2006-08-24
MY135770A (en)	2008-06-30
UY25310A1 (es)	1999-07-19
AP1441A (en)	2005-07-30
NO20003068L (no)	2000-06-15
SK286197B6 (sk)	2008-05-06
HUP0100500A3 (en)	2002-08-28
OA11634A (en)	2004-11-22
GB9726568D0 (en)	1998-02-11
CN101412714A (zh)	2009-04-22
US7045633B2 (en)	2006-05-16
ZA9811505B (en)	2000-11-06
CO4990927A1 (es)	2000-12-26
US20040097553A1 (en)	2004-05-20
DZ2680A1 (fr)	2005-02-20
EG21417A (en)	2001-10-31

Legal Events

Date	Code	Title	Description
2009-12-11	FC	Refusal

Publication	Publication Date	Title
NO992524L (no)	1999-05-26	Konsenserte bicykliske pyrimidin-derivater
AR023564A1 (es)	2002-09-04	Una forma polimorfica de sal del acido maleico derivado del tiazolidina-2,4 diona, una composicion farmaceutica y el uso del mismo para la fabricacion deun medicamento
IL78831A (en)	1990-11-29	6-(thiazolidin-2,4-dion-5-ylmethyl)chromans and structurally related compounds as hypoglycemic agents
AR031069A1 (es)	2003-09-10	Cristal de un compuesto benzimidazol, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima
UY25305A1 (es)	2000-12-29	Hidrato de la sal del ácido maleico de la 5-[4-[2-(n-metil-n-2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona
AR017214A1 (es)	2001-08-22	Un proceso para preparar un hidrato de la sal del acido maleico de 5-[4[2-(n-metil-n-(2-piridil)amino)-etoxi]bencil]tiazolidin-2,4-diona
AR023561A1 (es)	2002-09-04	Una forma polimorfica del acido maleico de un derivado de tiazolidin-2, 4 diona, una composicion farmaceutica y el uso de dicho polimorfo para lafabricacion de un medicamento
EA200000656A1 (ru)	2000-12-25	Замещенное производное тиазолидиндиона, способ его получения и его фармацевтическое применение
AP1607A (en)	2006-05-03	Thiazolidinedione derivative and its use as antidiabetic.
AR015894A1 (es)	2001-05-30	Uso de 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona e insulina para la preparacion de un medicamento y composicion farmaceuticaque contiene dichos compuestos
NZ513922A (en)	2001-09-28	Composition comprising 5-Ä4-Ä2-(N-methyl-N-2-pyridyl)-amino)ethoxy!benzyl!thiazolidine-2-4-dione
EA200101101A1 (ru)	2002-04-25	Новый фармацевтический препарат
AR023563A1 (es)	2002-09-04	Monohidrato de hidrocloruro de un derivado de tiazolidin-2,4-diona, una composicion farmaceutica y el uso del mismo para la fabricacion de un medicamento
HUP9900320A3 (en)	1999-11-29	Optically active thiazolidinone derivatives, preparation thereof, pharmageutical compositions containing these compounds as active ingredients and use of thia-or oxazolidine derivatives for preparation of pharmaceutical compositions
ECSP982779A (es)	1999-05-17	Un hidrato de la sal de acido maleico, proceso para la preparacion, composicion farmaceutica y su uso en medicina
AR017867A1 (es)	2001-10-24	Un hidrato de la sal del acido maleico de 5-4-2-(n-metil-n(2-piridil)amino)etoxi bencil tiazolidin-2,4-diona, un proceso para su preparacion, una composicion farmaceutica que lo comprende y el uso del mismo para la fabricacion de un medicamento.
AU2001284285A1 (en)	2002-03-22	A thiazolidinedione derivative and its use as antidiabetic
ECSP982780A (es)	1999-05-17	Nuevo producto farmaceutico proceso para su preparacion y su uso en medicina
ECSP003434A (es)	2000-07-21	Nuevos compuestos
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