AR020090A1 - Celula vegetal monocotiledonea o semilla de ella,planta o parte de una planta, metodo para hacer una celula vegetal monocotiledonea, metodo para hacer unaplanta, uso de una construccion de expresion para producir una celula de planta o semilla monocotiledonea, y uso de una construccion de expresion - Google Patents
Celula vegetal monocotiledonea o semilla de ella,planta o parte de una planta, metodo para hacer una celula vegetal monocotiledonea, metodo para hacer unaplanta, uso de una construccion de expresion para producir una celula de planta o semilla monocotiledonea, y uso de una construccion de expresionInfo
- Publication number
- AR020090A1 AR020090A1 ARP990102815A ARP990102815A AR020090A1 AR 020090 A1 AR020090 A1 AR 020090A1 AR P990102815 A ARP990102815 A AR P990102815A AR P990102815 A ARP990102815 A AR P990102815A AR 020090 A1 AR020090 A1 AR 020090A1
- Authority
- AR
- Argentina
- Prior art keywords
- plant
- polypeptide
- cell
- expression
- seed
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000010276 construction Methods 0.000 title abstract 3
- 235000013311 vegetables Nutrition 0.000 title 2
- 229920001184 polypeptide Polymers 0.000 abstract 12
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 12
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 12
- 210000004027 cell Anatomy 0.000 abstract 10
- 241000196324 Embryophyta Species 0.000 abstract 9
- 108091026890 Coding region Proteins 0.000 abstract 4
- 241000209510 Liliopsida Species 0.000 abstract 2
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 2
- 230000014759 maintenance of location Effects 0.000 abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 102100039371 ER lumen protein-retaining receptor 1 Human genes 0.000 abstract 1
- 101000812437 Homo sapiens ER lumen protein-retaining receptor 1 Proteins 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 235000007164 Oryza sativa Nutrition 0.000 abstract 1
- 241000209140 Triticum Species 0.000 abstract 1
- 235000021307 Triticum Nutrition 0.000 abstract 1
- 210000003763 chloroplast Anatomy 0.000 abstract 1
- 210000002472 endoplasmic reticulum Anatomy 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 235000009566 rice Nutrition 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8221—Transit peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Célula vegetal monocotiledonea o semilla de ella que contiene un polipéptido de mamífero, producido por la expresion, dentro de la célula o de la semilla,a paartir de un cassette de expresion, que comprende una secuencia de codificacion para el polipéptido , de modo tal que en la célula vegetal o la semilla hayaun rasgo adicional seleccinado del grupo formado por: (a) el polipéptido que se expresa fusionado a una senal de retencion del retículo endoplasmático (RE);(b) la secuencia de codificacion para el polipéptido que está precedida, en el cassette de expresion, por una secuencia líder 5 no traducida (5 UTR); (c) elpolipéptido que se expresa fusionado al péptido líder; (d) cualquier combinacion de un par formado entre (a),(b) y (c); y (e)una combinacion de (a), (b) y(c). Planta o parte de una planta, método para hacer una célula vegetal monocotiledonea, método para hacer una planta, uso de una construccion de expresionpara producir una célula de planta o semilla monocotiledonea. Usode una construccion de expresion para producir una planta transgénica. Método para producirplantas, células o semillas monocotiledoneas, por ejemplo, arroz o trigo, con un polipéptido de mamífero, como ser un anticuerpo o fragmento del mismo,producido por la expresion dentro de la célula o semilla de un casete de expresion que comprende una secuencia codificante para el polipéptido. Para aumentarel rendimiento del polipéptido dentro de la célula o semillas, la secuencia codificante puede fusionarse a secuencias adicionales de modo tal que elpolipéptido se fusiona a una senal de retencion ER, tal como, KDEL o HDEL,y/o a un péptido líder,tal como,una senal para dirigir un objetivo a los cloroplastosTambién para aumentar el rendimiento, la secuencia codificante para el polipéptido puede ser fusionada a secuencias adicionales, por ejemplo, a una secuencialíder no traducida 5. La célula o semilla puede contener uno o más casetes de expresion donde cada uno codifica una parte del polipéptido, por ejemplo, unacadena de un polipéptido multi-cadena. Se refiere a planta, célula o semilla transgénica obtenible por los métodos descriptos y a casetes de expresion para
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8932298P | 1998-06-15 | 1998-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR020090A1 true AR020090A1 (es) | 2002-04-10 |
Family
ID=22217017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990102815A AR020090A1 (es) | 1998-06-15 | 1999-06-11 | Celula vegetal monocotiledonea o semilla de ella,planta o parte de una planta, metodo para hacer una celula vegetal monocotiledonea, metodo para hacer unaplanta, uso de una construccion de expresion para producir una celula de planta o semilla monocotiledonea, y uso de una construccion de expresion |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20020078472A1 (es) |
| EP (1) | EP1088061A4 (es) |
| AR (1) | AR020090A1 (es) |
| AU (1) | AU4571699A (es) |
| BR (1) | BR9911270A (es) |
| CA (1) | CA2330933A1 (es) |
| MX (1) | MXPA00012520A (es) |
| WO (1) | WO1999066026A2 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9915543A (pt) * | 1998-10-16 | 2001-08-14 | Fraunhofer Ges Forschung | Resistência a doenças por plantas mediada por patogenicidas moleculares |
| US20030041353A1 (en) | 2001-04-18 | 2003-02-27 | Henry Daniell | Mutiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants |
| AU2001245358A1 (en) * | 2000-02-29 | 2001-09-12 | Auburn University | Production of antibodies in transgenic plastids |
| CA2401958A1 (en) * | 2000-02-29 | 2001-09-07 | Auburn University | Multiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants |
| US20020174453A1 (en) * | 2001-04-18 | 2002-11-21 | Henry Daniell | Production of antibodies in transgenic plastids |
| US7304208B2 (en) | 2000-05-02 | 2007-12-04 | Ventria Bioscience | Expression of human serum albumin (HSA) in monocot seeds |
| GB2364705A (en) * | 2000-07-14 | 2002-02-06 | Icgeb | Fusion protein expression in plastids |
| US6472176B2 (en) * | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| JP2005525081A (ja) | 2001-06-05 | 2005-08-25 | カレン ケイ． オオイシ | 植物からの生物活性ミュラー管抑制物質を含むＴＧＦ−βタンパク質の遺伝子発現および産生法 |
| US8558058B2 (en) * | 2001-12-06 | 2013-10-15 | Applied Biotechnology Institute | Monocotyledonous seed expressing exo-1,4B-glucanase |
| ES2224792B1 (es) * | 2002-06-28 | 2007-02-16 | Era Plantech, S.L. | Produccion de peptidos y proteinas por acumulacion de cuerpos proteicos derivados de reticulos endoplasmico en plantas. |
| JP2007517504A (ja) * | 2003-12-09 | 2007-07-05 | ベントリア バイオサイエンス | 融合担体として種子貯蔵蛋白を利用する植物種子中の融合ポリペプチドの高水準発現 |
| JP2008507258A (ja) * | 2004-04-22 | 2008-03-13 | フラウンホーファー・ゲゼルシャフト ツーァ フェルデルンク デァ アンゲヴァンテン フォルシュンク エー ファウ | 連鎖球菌表面抗原ｉ／ｉｉに特異的に結合する二重特異性抗体および前記の使用の方法 |
| JP2008515454A (ja) * | 2004-10-13 | 2008-05-15 | プロタリクス リミテッド | 植物細胞培養における抗体製造のシステムおよび方法 |
| WO2006066340A1 (en) * | 2004-12-21 | 2006-06-29 | Grain Biotech Australia Pty Ltd | A method for the high expression of immunoglobulin in plants |
| US20100047164A1 (en) * | 2008-04-11 | 2010-02-25 | Duke University | Anti-Tumor Antibodies |
| US10308948B2 (en) | 2011-07-27 | 2019-06-04 | Applied Biotechnology Institute, Inc. | Method of increasing expression of nucleic acid molecules in plants using multiple transcription units |
| CA3169722A1 (en) * | 2020-03-02 | 2021-09-10 | Deshui Zhang | Enhanced expression yield of immunoglobulin a in eukaryotes |
| KR102557824B1 (ko) * | 2020-08-18 | 2023-07-20 | 주식회사 바이오앱 | 식물 발현 재조합 지카바이러스 외피단백질을 포함하는 백신 조성물 및 이의 제조방법 |
| EP4652189A1 (en) * | 2023-01-19 | 2025-11-26 | Asterix Foods Ltd | Glycosylated animal protein expression in plant cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693506A (en) * | 1993-11-16 | 1997-12-02 | The Regents Of The University Of California | Process for protein production in plants |
| US5824870A (en) * | 1995-11-06 | 1998-10-20 | Baszczynski; Chris | Commercial production of aprotinin in plants |
| AU4173497A (en) * | 1996-09-03 | 1998-03-26 | Monsanto Company | Monocot seed gene expression system |
-
1999
- 1999-06-11 AR ARP990102815A patent/AR020090A1/es unknown
- 1999-06-15 AU AU45716/99A patent/AU4571699A/en not_active Abandoned
- 1999-06-15 BR BR9911270-1A patent/BR9911270A/pt not_active Application Discontinuation
- 1999-06-15 US US09/333,527 patent/US20020078472A1/en not_active Abandoned
- 1999-06-15 MX MXPA00012520A patent/MXPA00012520A/es unknown
- 1999-06-15 WO PCT/US1999/013584 patent/WO1999066026A2/en not_active Ceased
- 1999-06-15 CA CA002330933A patent/CA2330933A1/en not_active Abandoned
- 1999-06-15 EP EP99928717A patent/EP1088061A4/en not_active Withdrawn
-
2002
- 2002-04-23 US US10/127,427 patent/US20030051275A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999066026A3 (en) | 2000-01-27 |
| WO1999066026A2 (en) | 1999-12-23 |
| EP1088061A2 (en) | 2001-04-04 |
| MXPA00012520A (es) | 2002-05-08 |
| CA2330933A1 (en) | 1999-12-23 |
| AU4571699A (en) | 2000-01-05 |
| EP1088061A4 (en) | 2005-03-16 |
| US20030051275A1 (en) | 2003-03-13 |
| US20020078472A1 (en) | 2002-06-20 |
| BR9911270A (pt) | 2001-03-13 |
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