AR020090A1 - Celula vegetal monocotiledonea o semilla de ella,planta o parte de una planta, metodo para hacer una celula vegetal monocotiledonea, metodo para hacer unaplanta, uso de una construccion de expresion para producir una celula de planta o semilla monocotiledonea, y uso de una construccion de expresion - Google Patents
Celula vegetal monocotiledonea o semilla de ella,planta o parte de una planta, metodo para hacer una celula vegetal monocotiledonea, metodo para hacer unaplanta, uso de una construccion de expresion para producir una celula de planta o semilla monocotiledonea, y uso de una construccion de expresionInfo
- Publication number
- AR020090A1 AR020090A1 ARP990102815A ARP990102815A AR020090A1 AR 020090 A1 AR020090 A1 AR 020090A1 AR P990102815 A ARP990102815 A AR P990102815A AR P990102815 A ARP990102815 A AR P990102815A AR 020090 A1 AR020090 A1 AR 020090A1
- Authority
- AR
- Argentina
- Prior art keywords
- plant
- polypeptide
- cell
- expression
- seed
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000010276 construction Methods 0.000 title abstract 3
- 235000013311 vegetables Nutrition 0.000 title 2
- 229920001184 polypeptide Polymers 0.000 abstract 12
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 12
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 12
- 210000004027 cell Anatomy 0.000 abstract 10
- 241000196324 Embryophyta Species 0.000 abstract 9
- 108091026890 Coding region Proteins 0.000 abstract 4
- 241000209510 Liliopsida Species 0.000 abstract 2
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 2
- 230000014759 maintenance of location Effects 0.000 abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 102100039371 ER lumen protein-retaining receptor 1 Human genes 0.000 abstract 1
- 101000812437 Homo sapiens ER lumen protein-retaining receptor 1 Proteins 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 235000007164 Oryza sativa Nutrition 0.000 abstract 1
- 241000209140 Triticum Species 0.000 abstract 1
- 235000021307 Triticum Nutrition 0.000 abstract 1
- 210000003763 chloroplast Anatomy 0.000 abstract 1
- 210000002472 endoplasmic reticulum Anatomy 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 235000009566 rice Nutrition 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8221—Transit peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Célula vegetal monocotiledonea o semilla de ella que contiene un polipéptido de mamífero, producido por la expresion, dentro de la célula o de la semilla,a paartir de un cassette de expresion, que comprende una secuencia de codificacion para el polipéptido , de modo tal que en la célula vegetal o la semilla hayaun rasgo adicional seleccinado del grupo formado por: (a) el polipéptido que se expresa fusionado a una senal de retencion del retículo endoplasmático (RE);(b) la secuencia de codificacion para el polipéptido que está precedida, en el cassette de expresion, por una secuencia líder 5 no traducida (5 UTR); (c) elpolipéptido que se expresa fusionado al péptido líder; (d) cualquier combinacion de un par formado entre (a),(b) y (c); y (e)una combinacion de (a), (b) y(c). Planta o parte de una planta, método para hacer una célula vegetal monocotiledonea, método para hacer una planta, uso de una construccion de expresionpara producir una célula de planta o semilla monocotiledonea. Usode una construccion de expresion para producir una planta transgénica. Método para producirplantas, células o semillas monocotiledoneas, por ejemplo, arroz o trigo, con un polipéptido de mamífero, como ser un anticuerpo o fragmento del mismo,producido por la expresion dentro de la célula o semilla de un casete de expresion que comprende una secuencia codificante para el polipéptido. Para aumentarel rendimiento del polipéptido dentro de la célula o semillas, la secuencia codificante puede fusionarse a secuencias adicionales de modo tal que elpolipéptido se fusiona a una senal de retencion ER, tal como, KDEL o HDEL,y/o a un péptido líder,tal como,una senal para dirigir un objetivo a los cloroplastosTambién para aumentar el rendimiento, la secuencia codificante para el polipéptido puede ser fusionada a secuencias adicionales, por ejemplo, a una secuencialíder no traducida 5. La célula o semilla puede contener uno o más casetes de expresion donde cada uno codifica una parte del polipéptido, por ejemplo, unacadena de un polipéptido multi-cadena. Se refiere a planta, célula o semilla transgénica obtenible por los métodos descriptos y a casetes de expresion para
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8932298P | 1998-06-15 | 1998-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR020090A1 true AR020090A1 (es) | 2002-04-10 |
Family
ID=22217017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990102815A AR020090A1 (es) | 1998-06-15 | 1999-06-11 | Celula vegetal monocotiledonea o semilla de ella,planta o parte de una planta, metodo para hacer una celula vegetal monocotiledonea, metodo para hacer unaplanta, uso de una construccion de expresion para producir una celula de planta o semilla monocotiledonea, y uso de una construccion de expresion |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20020078472A1 (es) |
| EP (1) | EP1088061A4 (es) |
| AR (1) | AR020090A1 (es) |
| AU (1) | AU4571699A (es) |
| BR (1) | BR9911270A (es) |
| CA (1) | CA2330933A1 (es) |
| MX (1) | MXPA00012520A (es) |
| WO (1) | WO1999066026A2 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2246093T3 (es) * | 1998-10-16 | 2006-02-01 | Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Patogenicida molecular que induce una resistencia a la enfermedad en las plantas. |
| EP1268832A4 (en) * | 2000-02-29 | 2003-04-02 | Univ Auburn | PRODUCTION OF ANTIBODIES IN TRANSGENIC PLASTIDES |
| WO2001064024A1 (en) * | 2000-02-29 | 2001-09-07 | Auburn University | Multiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants |
| US20020174453A1 (en) * | 2001-04-18 | 2002-11-21 | Henry Daniell | Production of antibodies in transgenic plastids |
| US20030041353A1 (en) | 2001-04-18 | 2003-02-27 | Henry Daniell | Mutiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants |
| US7304208B2 (en) * | 2000-05-02 | 2007-12-04 | Ventria Bioscience | Expression of human serum albumin (HSA) in monocot seeds |
| GB2364705A (en) * | 2000-07-14 | 2002-02-06 | Icgeb | Fusion protein expression in plastids |
| US6472176B2 (en) * | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| US20030033637A1 (en) | 2001-06-05 | 2003-02-13 | Croptech Corporation | Gene expression and production of TGF-beta proteins including bioactive mullerian inhibiting substance from plants |
| US8558058B2 (en) * | 2001-12-06 | 2013-10-15 | Applied Biotechnology Institute | Monocotyledonous seed expressing exo-1,4B-glucanase |
| ES2224792B1 (es) * | 2002-06-28 | 2007-02-16 | Era Plantech, S.L. | Produccion de peptidos y proteinas por acumulacion de cuerpos proteicos derivados de reticulos endoplasmico en plantas. |
| US20070150976A1 (en) * | 2003-12-09 | 2007-06-28 | Ventria Bioscience | High-level expression of fusion polypeptides in plant seeds utilizing seed-storage proteins as fusion carriers |
| JP2008507258A (ja) * | 2004-04-22 | 2008-03-13 | フラウンホーファー・ゲゼルシャフト ツーァ フェルデルンク デァ アンゲヴァンテン フォルシュンク エー ファウ | 連鎖球菌表面抗原ｉ／ｉｉに特異的に結合する二重特異性抗体および前記の使用の方法 |
| ATE468390T1 (de) * | 2004-10-13 | 2010-06-15 | Protalix Ltd | System und verfahren zur produktion von antikörpern in der pflanzenzellkultur |
| WO2006066340A1 (en) * | 2004-12-21 | 2006-06-29 | Grain Biotech Australia Pty Ltd | A method for the high expression of immunoglobulin in plants |
| US20100047164A1 (en) * | 2008-04-11 | 2010-02-25 | Duke University | Anti-Tumor Antibodies |
| US10308948B2 (en) | 2011-07-27 | 2019-06-04 | Applied Biotechnology Institute, Inc. | Method of increasing expression of nucleic acid molecules in plants using multiple transcription units |
| JP2023515684A (ja) * | 2020-03-02 | 2023-04-13 | ベントリア、バイオサイエンス、インコーポレイテッド | 真核生物における免疫グロブリンの発現収率の改善 |
| KR102557824B1 (ko) * | 2020-08-18 | 2023-07-20 | 주식회사 바이오앱 | 식물 발현 재조합 지카바이러스 외피단백질을 포함하는 백신 조성물 및 이의 제조방법 |
| WO2024154002A1 (en) * | 2023-01-19 | 2024-07-25 | Asterix Foods Ltd | Glycosylated animal protein expression in plant cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693506A (en) * | 1993-11-16 | 1997-12-02 | The Regents Of The University Of California | Process for protein production in plants |
| US5824870A (en) * | 1995-11-06 | 1998-10-20 | Baszczynski; Chris | Commercial production of aprotinin in plants |
| WO1998010062A1 (en) * | 1996-09-03 | 1998-03-12 | Monsanto Company | Monocot seed gene expression system |
-
1999
- 1999-06-11 AR ARP990102815A patent/AR020090A1/es unknown
- 1999-06-15 BR BR9911270-1A patent/BR9911270A/pt not_active Application Discontinuation
- 1999-06-15 AU AU45716/99A patent/AU4571699A/en not_active Abandoned
- 1999-06-15 WO PCT/US1999/013584 patent/WO1999066026A2/en not_active Ceased
- 1999-06-15 US US09/333,527 patent/US20020078472A1/en not_active Abandoned
- 1999-06-15 CA CA002330933A patent/CA2330933A1/en not_active Abandoned
- 1999-06-15 EP EP99928717A patent/EP1088061A4/en not_active Withdrawn
- 1999-06-15 MX MXPA00012520A patent/MXPA00012520A/es unknown
-
2002
- 2002-04-23 US US10/127,427 patent/US20030051275A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU4571699A (en) | 2000-01-05 |
| MXPA00012520A (es) | 2002-05-08 |
| EP1088061A4 (en) | 2005-03-16 |
| EP1088061A2 (en) | 2001-04-04 |
| US20030051275A1 (en) | 2003-03-13 |
| BR9911270A (pt) | 2001-03-13 |
| CA2330933A1 (en) | 1999-12-23 |
| US20020078472A1 (en) | 2002-06-20 |
| WO1999066026A3 (en) | 2000-01-27 |
| WO1999066026A2 (en) | 1999-12-23 |
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