AR036412A2 - Un metodo de procesamiento de muestra de citometria de flujo, un metodo de crear un especimen de esperma sexuado y un metodo para crear un mamifero - Google Patents
Un metodo de procesamiento de muestra de citometria de flujo, un metodo de crear un especimen de esperma sexuado y un metodo para crear un mamiferoInfo
- Publication number
- AR036412A2 AR036412A2 ARP020103317A ARP020103317A AR036412A2 AR 036412 A2 AR036412 A2 AR 036412A2 AR P020103317 A ARP020103317 A AR P020103317A AR P020103317 A ARP020103317 A AR P020103317A AR 036412 A2 AR036412 A2 AR 036412A2
- Authority
- AR
- Argentina
- Prior art keywords
- nozzle
- creating
- sample
- torsion
- individual
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 9
- 238000000684 flow cytometry Methods 0.000 title abstract 3
- 238000003672 processing method Methods 0.000 title 1
- 238000005070 sampling Methods 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000001133 acceleration Effects 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000009027 insemination Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N15/1409—Handling samples, e.g. injecting samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1415—Control of particle position
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Un método de procesamiento de muestras de citometría de flujo, un método de crear un espécimen de esperma sexuado y un método para crear un mamífero. La disposición de boquilla mejorada para un citómetro de flujo y métodos que acompanan han sido inventados para una orientación altamente eficiente y proceso de clasificación de una muestra plana e ítems dedicados tales como células de esperma de equinos o de bovinos. La disposición de boquilla mejorada comprende una boquilla con una geometría de superficie interior novedosa que puede acelerar gentilmente las células e incluso incluir un elemento de superficie interior de torsión individual tipo elíptica dentro de la boquilla, por ejemplo una boquilla de orientación de torsión individual. El elemento de superficie interior de torsión individual tipo elíptica puede tener una superficie de flujo laminar y puede producir el paso de flujo más simple para aplicar fuerzas mínimas las cuales actúan en naturaleza de aceleración o fuerzas hidrodinámicas de orientación, es decir, las fuerzas de orientación de torsión individual, para orientar una muestra plana tal como células de esperma animales dentro de una dirección apropiada para un análisis y proceso de clasificación eficiente en uso clínico para investigación y para la industria de inseminación animal. Reivindicación 1: Un método de procesamiento de muestras de citometría de flujo, caracterizado porque comprende los pasos de a) establecer un fluido de envainado; b) inyectar una muestra dentro de dicho fluido de envainado en un punto de inyección; c) establecer una superficie de torsión individual en la boquilla que presenta un eje central alrededor del cual una torsión es aplicada; d) generar fuerzas hidrodinámicas de torsión individuales a partir de dicha superficie de torsión individual; e) orientar dicha muestra con dicha fuerzas de hidrodinámicas de torsión individual; f) expulsar dicha muestra desde dicha boquilla; g) analizar dicha muestra.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/454,488 US6263745B1 (en) | 1999-12-03 | 1999-12-03 | Flow cytometer nozzle and flow cytometer sample handling methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR036412A2 true AR036412A2 (es) | 2004-09-08 |
Family
ID=23804813
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000106346A AR026683A1 (es) | 1999-12-03 | 2000-12-01 | Boquilla mejorada para citometro de flujo y metodos para el manejo de muestra de citometro de flujo |
| ARP020103317A AR036412A2 (es) | 1999-12-03 | 2002-09-02 | Un metodo de procesamiento de muestra de citometria de flujo, un metodo de crear un especimen de esperma sexuado y un metodo para crear un mamifero |
| ARP060102227A AR053879A2 (es) | 1999-12-03 | 2006-05-29 | Un metodo de procesamiento de muestra de citometria de flujo , un metodo de crear un especimen de esperma sexuado y un metodo para crear un mamifero |
| ARP060102226A AR053878A2 (es) | 1999-12-03 | 2006-05-29 | Una disposicion de citometro de flujo, un especimen de esperma sexuado y un mamifero |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000106346A AR026683A1 (es) | 1999-12-03 | 2000-12-01 | Boquilla mejorada para citometro de flujo y metodos para el manejo de muestra de citometro de flujo |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060102227A AR053879A2 (es) | 1999-12-03 | 2006-05-29 | Un metodo de procesamiento de muestra de citometria de flujo , un metodo de crear un especimen de esperma sexuado y un metodo para crear un mamifero |
| ARP060102226A AR053878A2 (es) | 1999-12-03 | 2006-05-29 | Una disposicion de citometro de flujo, un especimen de esperma sexuado y un mamifero |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US6263745B1 (es) |
| EP (3) | EP1238261B1 (es) |
| JP (2) | JP5019497B2 (es) |
| KR (3) | KR100909862B1 (es) |
| CN (1) | CN1402831A (es) |
| AR (4) | AR026683A1 (es) |
| AT (1) | ATE467113T1 (es) |
| AU (1) | AU783000B2 (es) |
| BR (1) | BRPI0016121B1 (es) |
| CA (3) | CA2822851C (es) |
| DE (1) | DE60044373D1 (es) |
| DK (3) | DK1238261T3 (es) |
| ES (2) | ES2342922T3 (es) |
| GB (1) | GB2372466A (es) |
| HU (1) | HUP0300587A2 (es) |
| IL (1) | IL149936A0 (es) |
| MX (1) | MXPA02005488A (es) |
| NO (1) | NO20022536L (es) |
| NZ (1) | NZ519275A (es) |
| PL (1) | PL355812A1 (es) |
| RU (1) | RU2002117447A (es) |
| TW (1) | TW538243B (es) |
| UY (1) | UY26469A1 (es) |
| WO (1) | WO2001040765A2 (es) |
Families Citing this family (106)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861265B1 (en) * | 1994-10-14 | 2005-03-01 | University Of Washington | Flow cytometer droplet formation system |
| DE69830598T2 (de) | 1997-01-31 | 2006-05-18 | The Horticulture And Food Research Institute Of New Zealand Limited | Optische vorrichtung und methode |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| US6071689A (en) | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
| NZ509434A (en) | 1998-07-30 | 2004-03-26 | Univ Colorado State Res Found | Equine system for non-surgical artificial insemination |
| US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
| US6263745B1 (en) | 1999-12-03 | 2001-07-24 | Xy, Inc. | Flow cytometer nozzle and flow cytometer sample handling methods |
| EP2258170B1 (en) | 2000-05-09 | 2017-07-12 | Xy, Llc | High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa |
| CN1633259A (zh) * | 2000-06-12 | 2005-06-29 | Xy公司 | 利用分离的带x－染色体和带y－染色体的精子群的综合兽群管理系统 |
| US20020118402A1 (en) * | 2000-09-19 | 2002-08-29 | Shaw Timothy C. | Film bridge for digital film scanning system |
| AU2002237689B2 (en) | 2000-11-29 | 2008-01-10 | Xy, Llc. | System to separate frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations |
| US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| ES2405320T3 (es) * | 2001-05-17 | 2013-05-30 | Beckman Coulter, Inc. | Citómetro de flujo con un sistema de alienación óptica automatizado activo |
| US7475853B2 (en) * | 2002-06-21 | 2009-01-13 | Darko Segota | Method and system for regulating external fluid flow over an object's surface, and particularly a wing and diffuser |
| US7296411B2 (en) * | 2002-06-21 | 2007-11-20 | Darko Segota | Method and system for regulating internal fluid flow within an enclosed or semi-enclosed environment |
| US7048505B2 (en) * | 2002-06-21 | 2006-05-23 | Darko Segota | Method and system for regulating fluid flow over an airfoil or a hydrofoil |
| US20050098685A1 (en) * | 2002-06-21 | 2005-05-12 | Darko Segota | Method and system for regulating pressure and optimizing fluid flow about a fuselage similar body |
| US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
| CA2532376C (en) | 2002-08-01 | 2015-05-12 | Colorado State University Research Foundation | Low pressure sperm cell separation system |
| BRPI0313476B1 (pt) | 2002-08-15 | 2015-06-23 | Xy Llc | Citômetro de fluxo de alta resolução |
| US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
| US7201875B2 (en) * | 2002-09-27 | 2007-04-10 | Becton Dickinson And Company | Fixed mounted sorting cuvette with user replaceable nozzle |
| CA2516481A1 (en) * | 2003-02-18 | 2004-09-02 | Board Of Regents, The University Of Texas System | Dielectric particle focusing |
| AU2012200711B2 (en) * | 2003-03-28 | 2012-09-20 | Inguran, Llc | "Method and apparatus for orientating sperm in a fluid stream" |
| ATE369867T1 (de) * | 2003-03-28 | 2007-09-15 | Monsanto Technology Llc | Verfahren zum anfärben von sperma |
| DK2308419T3 (da) | 2003-03-28 | 2016-06-06 | Inguran Llc | Fremgangsmåde til bedømmelse af farvningstilstandene for dyresperm, som skal sorteres. |
| NZ544103A (en) | 2003-05-15 | 2010-10-29 | Xy Llc | Efficient haploid cell sorting for flow cytometer systems |
| NZ530972A (en) * | 2004-02-05 | 2005-04-29 | Embrionics Ltd | A method and apparatus for orientating and selecting cells |
| JP2007531523A (ja) | 2004-03-29 | 2007-11-08 | モンサント テクノロジー エルエルシー | Ｘまたはｙ染色体担持豊富化集団に仕分けるための精子懸濁液 |
| ATE455291T1 (de) * | 2004-03-29 | 2010-01-15 | Inguran Llc | Verwendung einer oxidations-/reduktionsreaktionen intrazellulär und/oder extrazellulär regulierenden zusammensetzung in einem anfärbe- oder sortierungsverfahren für spermatozoen |
| DE102005052752A1 (de) * | 2005-11-04 | 2007-05-10 | Clondiag Chip Technologies Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
| CA2574499C (en) | 2004-07-22 | 2016-11-29 | Monsanto Technology Llc | Process for enriching a population of sperm cells |
| US7340957B2 (en) | 2004-07-29 | 2008-03-11 | Los Alamos National Security, Llc | Ultrasonic analyte concentration and application in flow cytometry |
| US7355696B2 (en) | 2005-02-01 | 2008-04-08 | Arryx, Inc | Method and apparatus for sorting cells |
| FR2883973B1 (fr) * | 2005-03-31 | 2007-11-16 | C2 Diagnostics Sa | Cuve pour dispositif optique d'analyse sanguine, appareil d'analyse equipe d'une telle cuve |
| US20070025879A1 (en) * | 2005-07-27 | 2007-02-01 | Dakocytomation Denmark A/S | Method and apparatus for syringe-based sample introduction within a flow cytometer |
| US7618770B2 (en) | 2005-07-29 | 2009-11-17 | Xy, Inc. | Methods and apparatus for reducing protein content in sperm cell extenders |
| US7835000B2 (en) | 2006-11-03 | 2010-11-16 | Los Alamos National Security, Llc | System and method for measuring particles in a sample stream of a flow cytometer or the like |
| ATE538377T1 (de) | 2007-04-02 | 2012-01-15 | Acoustic Cytometry Systems Inc | Verfahren zur verbesserten analyse von in einem akustischen feld fokussierten zellen und partikeln |
| US7837040B2 (en) * | 2007-04-09 | 2010-11-23 | Los Alamos National Security, Llc | Acoustic concentration of particles in fluid flow |
| US8083068B2 (en) | 2007-04-09 | 2011-12-27 | Los Alamos National Security, Llc | Apparatus for separating particles utilizing engineered acoustic contrast capture particles |
| US8528406B2 (en) | 2007-10-24 | 2013-09-10 | Los Alamos National Security, LLP | Method for non-contact particle manipulation and control of particle spacing along an axis |
| US8263407B2 (en) | 2007-10-24 | 2012-09-11 | Los Alamos National Security, Llc | Method for non-contact particle manipulation and control of particle spacing along an axis |
| CA2708751A1 (en) | 2007-12-14 | 2009-06-25 | Minitube Of America, Inc. | Gender-specific separation of sperm cells and embryos |
| US8266951B2 (en) | 2007-12-19 | 2012-09-18 | Los Alamos National Security, Llc | Particle analysis in an acoustic cytometer |
| US8714014B2 (en) | 2008-01-16 | 2014-05-06 | Life Technologies Corporation | System and method for acoustic focusing hardware and implementations |
| JP4661942B2 (ja) * | 2008-05-13 | 2011-03-30 | ソニー株式会社 | マイクロチップとその流路構造 |
| US20110076712A1 (en) * | 2008-06-13 | 2011-03-31 | Xy, Llc. | Lubricious microfludic flow path system |
| US20100009333A1 (en) * | 2008-07-08 | 2010-01-14 | Beckman Coulter, Inc. | Methods for Acoustic Particle Focusing in Biological Sample Analyzers |
| DE102008033570B4 (de) * | 2008-07-15 | 2010-09-30 | Masterrind Gmbh | Verfahren zur Zellidentifikation und Zellsortierung |
| JP5487638B2 (ja) | 2009-02-17 | 2014-05-07 | ソニー株式会社 | 微小粒子分取のための装置及びマイクロチップ |
| WO2011068764A2 (en) * | 2009-12-04 | 2011-06-09 | Life Technologies Corporation | Apparatuses, systems, methods, and computer readable media for acoustic flow cytometry |
| US20110236923A1 (en) * | 2010-03-23 | 2011-09-29 | Genetics & Ivf Institute | Method for staining and sorting of a small volume of sperm |
| WO2011123166A2 (en) | 2010-04-01 | 2011-10-06 | Inguran, Llc | Methods and systems for reducing dna fragmentation in a processed sperm sample |
| EP2671065B1 (en) | 2011-02-04 | 2019-07-10 | Cytonome/ST, LLC | Particle sorting apparatus and method |
| DE102011006081A1 (de) | 2011-03-24 | 2012-09-27 | Masterrind Gmbh | Düse zur Ausrichtung eines Flüssigkeitsteilstroms |
| DE102011006080B4 (de) | 2011-03-24 | 2015-06-18 | Masterrind Gmbh | Vorrichtung und Verfahren zur Fraktionierung von Säugerspermatozoen |
| DE102011075711A1 (de) | 2011-05-12 | 2012-11-15 | Masterrind Gmbh | Düse zur Partikelausrichtung im Flüssigkeitsstrom |
| EP2707699B1 (en) | 2011-05-12 | 2021-07-07 | Xy, Llc | Uv diode laser excitation in flow cytometry |
| JP2013024629A (ja) * | 2011-07-19 | 2013-02-04 | Sysmex Corp | フローサイトメータ |
| CN103013811A (zh) * | 2011-09-20 | 2013-04-03 | 北京富通华投资有限公司 | 精子分选仪 |
| US9433195B2 (en) | 2012-06-06 | 2016-09-06 | Inguran, Llc | Methods for increasing genetic progress in a line or breed of swine using sex-selected sperm cells |
| US9888990B2 (en) | 2012-06-06 | 2018-02-13 | Inguran, Llc | Methods for use of sex sorted semen to improve genetic management in swine |
| CN102795668B (zh) * | 2012-09-12 | 2014-07-09 | 西南大学 | 一种vo2的制备方法 |
| US10379029B2 (en) | 2012-09-18 | 2019-08-13 | Cytonome/St, Llc | Flow cell |
| EP2898325B1 (en) | 2012-09-19 | 2023-05-03 | Inguran, LLC | Nozzle assembly for a flow cytometer system |
| US11668640B2 (en) | 2015-03-06 | 2023-06-06 | Inguran, Llc | Nozzle assembly for a flow cytometry system and methods of manufacture |
| NZ630368A (en) | 2012-09-19 | 2016-06-24 | Inguran Llc | Flow cytometer nozzle tip |
| DE102012108989B3 (de) * | 2012-09-24 | 2014-01-23 | Eads Deutschland Gmbh | Detektionsvorrichtung sowie Verfahren zur automatischen Detektion von Partikeln |
| AU2013325222B2 (en) | 2012-10-05 | 2016-06-23 | Inguran, Llc | Methods of processing sperm for sex sorting |
| DE202012105015U1 (de) | 2012-12-21 | 2013-03-05 | Laser Zentrum Hannover E.V. | Einrichtung mit einem inneren und einem äußeren Funktionselement |
| JP2014174139A (ja) * | 2013-03-13 | 2014-09-22 | Sony Corp | 流路デバイス、粒子分取装置、粒子流出方法、及び粒子分取方法 |
| AU2013202632B2 (en) * | 2013-03-14 | 2015-04-16 | Inguran, Llc | Apparatus and methods for high throughput sperm sorting |
| US10371622B2 (en) | 2013-03-14 | 2019-08-06 | Inguran, Llc | Device for high throughput sperm sorting |
| US10662408B2 (en) | 2013-03-14 | 2020-05-26 | Inguran, Llc | Methods for high throughput sperm sorting |
| RU2627379C2 (ru) | 2013-03-14 | 2017-08-08 | Ингуран, Ллк | Установка и способы для высокопроизводительной сортировки спермы |
| US9757726B2 (en) | 2013-03-14 | 2017-09-12 | Inguran, Llc | System for high throughput sperm sorting |
| DE102013208584A1 (de) * | 2013-05-08 | 2014-11-13 | Masterrind Gmbh | Düse und Verfahren für die Durchflusszytometrie |
| US10870175B2 (en) * | 2013-09-18 | 2020-12-22 | Cytonome/St, Llc | Microfluidic flow-through elements and methods of manufacture of same |
| CN103555662B (zh) * | 2013-10-31 | 2015-09-16 | 大连金弘基种畜有限公司 | 将四溴化1,1,2,2-四-[4-(2-三乙基乙氧基胺基)]苯乙烯应用于精子分离 |
| JP2015222202A (ja) * | 2014-05-22 | 2015-12-10 | ソニー株式会社 | 粒子分析装置 |
| CA2905670C (en) | 2014-09-26 | 2025-08-05 | Inguran, Llc | SEX-SORTED SPERM EXPRESSING A DOSE-RESPONSE AND PRODUCTION METHODS FOR SEX-SORTED SPERM EXPRESSING A DOSE-RESPONSE |
| WO2016090310A1 (en) | 2014-12-05 | 2016-06-09 | Inguran, Llc | Cell processing using magnetic particles |
| WO2016154131A1 (en) * | 2015-03-23 | 2016-09-29 | New York University | Systems and methods for selecting cellular strains |
| WO2017202932A2 (en) | 2016-05-24 | 2017-11-30 | Cellix Limited | An apparatus for microfluidic flow cytometry analysis of a particulate containing fluid |
| USD869676S1 (en) | 2017-03-28 | 2019-12-10 | Becton, Dickinson And Company | Particle sorting module |
| USD868991S1 (en) | 2017-03-28 | 2019-12-03 | Becton, Dickinson And Company | Register block |
| FR3068469B1 (fr) * | 2017-06-28 | 2020-09-11 | Diagdev | Cuve de mesure pour le denombrement et/ou la caracterisation de cellules |
| RU2020107243A (ru) | 2017-07-19 | 2021-08-20 | Ингуран, Ллк | Способ и система, включающие в себя оптическую систему формирования пучка и стабилизацию пучка |
| USD876668S1 (en) | 2018-01-30 | 2020-02-25 | Becton, Dickinson And Company | Particle sorting module mount |
| USD872296S1 (en) | 2018-01-30 | 2020-01-07 | Becton, Dickinson And Company | Particle sorting module |
| USD864415S1 (en) | 2018-01-30 | 2019-10-22 | Becton, Dickinson And Company | Particle sorting system |
| USD882817S1 (en) | 2018-01-30 | 2020-04-28 | Becton, Dickinson And Company | Sample container |
| WO2019199853A1 (en) | 2018-04-09 | 2019-10-17 | Inguran, Llc | Methods and compositions for determining the presence or absence of dna aberrations |
| US20210237078A1 (en) * | 2018-04-25 | 2021-08-05 | Miriam Cather Simpson | Systems, devices and methods associated with microfluidic systems |
| US11629330B2 (en) | 2019-03-19 | 2023-04-18 | Inguran, Llc | Method for improved sperm cell populations |
| AU2020253637B2 (en) | 2019-04-05 | 2025-04-17 | Asp Health Inc. | Consumable components in fluidic sample dispensing systems and methods |
| EP3771899A1 (en) * | 2019-07-30 | 2021-02-03 | Diatron MI PLC | Flow cytometer |
| CN110763611A (zh) * | 2019-10-18 | 2020-02-07 | 中国科学院大气物理研究所 | 一种基于鞘气绕流原理的气溶胶粒子束喷射装置 |
| US11584662B2 (en) | 2020-03-16 | 2023-02-21 | Inguran, Llc | Systems and method for correction of positionally dependent electromagnetic radiation detected from objects within a fluid column |
| CN111521549B (zh) * | 2020-05-13 | 2021-01-01 | 洹仪科技(上海)有限公司 | 一种颗粒分选装置及方法 |
| US20230236173A1 (en) | 2020-06-22 | 2023-07-27 | Westfaelische Wilhelms-Universitaet Muenster | Sperm stratification |
| US11858008B2 (en) | 2021-03-26 | 2024-01-02 | Cytonome/St, Llc | Systems and methods for particle sorting with automated adjustment of operational parameters |
| WO2023186905A1 (en) | 2022-03-29 | 2023-10-05 | LAVA Therapeutics N.V. | A method of treating a hematological cancer following screening for cd1d positive tumor cells |
| US12533683B2 (en) * | 2022-03-29 | 2026-01-27 | A. Raymond Et Cie | Blended jet spray nozzle |
| EP4685494A1 (en) * | 2023-03-22 | 2026-01-28 | MBD Co., Ltd. | High-speed dispensing spotter for bio sample, and cell dispensing method using same |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3661460A (en) * | 1970-08-28 | 1972-05-09 | Technicon Instr | Method and apparatus for optical analysis of the contents of a sheathed stream |
| US3893766A (en) * | 1973-06-14 | 1975-07-08 | Coulter Electronics | Apparatus for orienting generally flat particles for slit-scan photometry |
| JPS5157484A (en) * | 1974-09-20 | 1976-05-19 | Coulter Electronics | Ryushihokozukesochi |
| US4362246A (en) | 1980-07-14 | 1982-12-07 | Adair Edwin Lloyd | Method of treating collected mammal semen and separating sperm into X Y components |
| US4660971A (en) | 1984-05-03 | 1987-04-28 | Becton, Dickinson And Company | Optical features of flow cytometry apparatus |
| NO156916C (no) * | 1985-07-10 | 1987-12-16 | Harald B Steen | Stroemningskammer for vaeskestroemsfotometer. |
| US5346990A (en) | 1987-04-08 | 1994-09-13 | Cytogam, Inc. | Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex |
| JPS63262565A (ja) * | 1987-04-20 | 1988-10-28 | Hitachi Ltd | フロ−セル |
| US4988619A (en) | 1987-11-30 | 1991-01-29 | United States Department Of Energy | Flow cytometry apparatus |
| JPH0618275Y2 (ja) * | 1989-03-09 | 1994-05-11 | 東亜医用電子株式会社 | フローセル |
| CA2055494C (en) | 1989-05-10 | 2000-01-18 | Lawrence Arthur Johnson | Method to preselect the sex of offspring |
| JP2808321B2 (ja) * | 1989-09-19 | 1998-10-08 | 東亜医用電子株式会社 | 細胞分析方法及び装置 |
| JPH0692931B2 (ja) * | 1991-03-26 | 1994-11-16 | 工業技術院長 | 液体中繊維状粒子分析計 |
| JP3075370B2 (ja) * | 1991-07-26 | 2000-08-14 | シスメックス株式会社 | 粒子分析用のサンプル扁平流形成装置 |
| JP3117751B2 (ja) * | 1991-07-26 | 2000-12-18 | シスメックス株式会社 | 粒子分析用のサンプル扁平流形成装置 |
| US5466572A (en) | 1992-09-03 | 1995-11-14 | Systemix, Inc. | High speed flow cytometric separation of viable cells |
| US5311290A (en) * | 1992-09-30 | 1994-05-10 | Pulp And Paper Research Institute Of Canada | Imaging apparatus and method of fiber analysis |
| US5371585A (en) | 1992-11-10 | 1994-12-06 | Pacific Scientific Company | Particle detecting instrument with sapphire detecting cell defining a rectangular flow path |
| JP3376662B2 (ja) * | 1993-01-26 | 2003-02-10 | 株式会社日立製作所 | フローセル装置 |
| JP3052665B2 (ja) * | 1993-01-26 | 2000-06-19 | 株式会社日立製作所 | フローセル装置 |
| US5483469A (en) | 1993-08-02 | 1996-01-09 | The Regents Of The University Of California | Multiple sort flow cytometer |
| US5601234A (en) * | 1994-08-01 | 1997-02-11 | Abbott Laboratories | Fluid nozzle and method of introducing a fluid |
| US5700692A (en) | 1994-09-27 | 1997-12-23 | Becton Dickinson And Company | Flow sorter with video-regulated droplet spacing |
| US5602039A (en) | 1994-10-14 | 1997-02-11 | The University Of Washington | Flow cytometer jet monitor system |
| US5602349A (en) | 1994-10-14 | 1997-02-11 | The University Of Washington | Sample introduction system for a flow cytometer |
| DE69532416T2 (de) | 1994-10-14 | 2004-12-02 | University Of Washington, Seattle | Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie |
| CN1638176A (zh) | 1994-10-18 | 2005-07-13 | 南加州大学 | 有机燃料电池及其运行方法和电极制作方法 |
| GB9707096D0 (en) * | 1997-04-08 | 1997-05-28 | Smithkline Beecham Plc | Novel device |
| US5985216A (en) | 1997-07-24 | 1999-11-16 | The United States Of America, As Represented By The Secretary Of Agriculture | Flow cytometry nozzle for high efficiency cell sorting |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| FR2777351B1 (fr) * | 1998-04-08 | 2000-06-23 | Hycel Diagnostics | Procede et dispositif de mesure de particules en suspension dans un liquide |
| US6263745B1 (en) | 1999-12-03 | 2001-07-24 | Xy, Inc. | Flow cytometer nozzle and flow cytometer sample handling methods |
| US9815403B2 (en) | 2016-01-13 | 2017-11-14 | Si-En Technology (Xiamen) Limited | LED driver chip for car reading light and state control method thereof |
-
1999
- 1999-12-03 US US09/454,488 patent/US6263745B1/en not_active Expired - Lifetime
-
2000
- 2000-11-29 EP EP00991511A patent/EP1238261B1/en not_active Expired - Lifetime
- 2000-11-29 MX MXPA02005488A patent/MXPA02005488A/es active IP Right Grant
- 2000-11-29 CN CN00816624A patent/CN1402831A/zh active Pending
- 2000-11-29 HU HU0300587A patent/HUP0300587A2/hu unknown
- 2000-11-29 DK DK00991511.7T patent/DK1238261T3/da active
- 2000-11-29 EP EP10001278.0A patent/EP2180307B1/en not_active Expired - Lifetime
- 2000-11-29 WO PCT/US2000/042350 patent/WO2001040765A2/en not_active Ceased
- 2000-11-29 GB GB0213051A patent/GB2372466A/en not_active Withdrawn
- 2000-11-29 PL PL00355812A patent/PL355812A1/xx unknown
- 2000-11-29 IL IL14993600A patent/IL149936A0/xx unknown
- 2000-11-29 DK DK10182264.1T patent/DK2264430T3/en active
- 2000-11-29 KR KR1020077011095A patent/KR100909862B1/ko not_active Expired - Fee Related
- 2000-11-29 AU AU32728/01A patent/AU783000B2/en not_active Expired
- 2000-11-29 ES ES00991511T patent/ES2342922T3/es not_active Expired - Lifetime
- 2000-11-29 KR KR1020027007131A patent/KR20020063584A/ko not_active Ceased
- 2000-11-29 JP JP2001542181A patent/JP5019497B2/ja not_active Expired - Fee Related
- 2000-11-29 KR KR1020077011096A patent/KR20070058711A/ko not_active Ceased
- 2000-11-29 DE DE60044373T patent/DE60044373D1/de not_active Expired - Lifetime
- 2000-11-29 BR BRPI0016121A patent/BRPI0016121B1/pt active IP Right Grant
- 2000-11-29 CA CA2822851A patent/CA2822851C/en not_active Expired - Lifetime
- 2000-11-29 CA CA2393121A patent/CA2393121C/en not_active Expired - Lifetime
- 2000-11-29 RU RU2002117447/28A patent/RU2002117447A/ru not_active Application Discontinuation
- 2000-11-29 AT AT00991511T patent/ATE467113T1/de active
- 2000-11-29 CA CA2739572A patent/CA2739572C/en not_active Expired - Lifetime
- 2000-11-29 ES ES10001278.0T patent/ES2445520T3/es not_active Expired - Lifetime
- 2000-11-29 DK DK10001278.0T patent/DK2180307T3/en active
- 2000-11-29 EP EP10182264.1A patent/EP2264430B1/en not_active Expired - Lifetime
- 2000-11-29 NZ NZ519275A patent/NZ519275A/en not_active IP Right Cessation
- 2000-11-30 TW TW089125453A patent/TW538243B/zh not_active IP Right Cessation
- 2000-12-01 AR ARP000106346A patent/AR026683A1/es active IP Right Grant
- 2000-12-04 UY UY26469A patent/UY26469A1/es not_active IP Right Cessation
-
2001
- 2001-07-20 US US09/909,483 patent/US6357307B2/en not_active Expired - Lifetime
-
2002
- 2002-03-13 US US10/098,036 patent/US6604435B2/en not_active Expired - Lifetime
- 2002-05-28 NO NO20022536A patent/NO20022536L/no not_active Application Discontinuation
- 2002-09-02 AR ARP020103317A patent/AR036412A2/es active IP Right Grant
-
2003
- 2003-08-12 US US10/640,337 patent/US6782768B2/en not_active Expired - Lifetime
-
2006
- 2006-05-29 AR ARP060102227A patent/AR053879A2/es active IP Right Grant
- 2006-05-29 AR ARP060102226A patent/AR053878A2/es active IP Right Grant
-
2011
- 2011-12-05 JP JP2011265651A patent/JP5762939B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR053879A2 (es) | Un metodo de procesamiento de muestra de citometria de flujo , un metodo de crear un especimen de esperma sexuado y un metodo para crear un mamifero | |
| Crane et al. | Microfluidics-enabled phenotyping, imaging, and screening of multicellular organisms | |
| ES2641524T3 (es) | Microanálisis de la función celular | |
| BRPI0408857A (pt) | aparelho, métodos e processos para separar partìculas e para prover esperma de animal separado por sexo | |
| ATE485397T1 (de) | Vorrichtung zur durchführung von pcr unter zeitnaher beobachtung der fluoreszenz | |
| Sivagnanam et al. | Exploring living multicellular organisms, organs, and tissues using microfluidic systems | |
| US20120251999A1 (en) | Vitrification systems and methods | |
| Liu et al. | Asymmetric drop coalescence launches fungal ballistospores with directionality | |
| CN1441652A (zh) | 微流控通道胚胎和/或卵母细胞处理,分析和生物评价 | |
| Wlodkowic et al. | Wormometry‐on‐a‐chip: Innovative technologies for in situ analysis of small multicellular organisms | |
| ES2172527T3 (es) | Sistema de muestreo de sangre con adaptador luer. | |
| WO2020041303A1 (en) | Systems and methods for sperm selection | |
| EP1876451A3 (en) | Handling method of body fluid sample and analysis apparatus using the same | |
| Kuncova et al. | Challenges in capillary pressure microinjection | |
| Bouloorchi Tabalvandani et al. | Microfluidics as an emerging paradigm for assisted reproductive technology: A sperm separation perspective | |
| CN104531504A (zh) | 一种利用层流和趋化作用分离细菌的微流控芯片装置 | |
| CN114289084B (zh) | 一种对线虫实施微电极检测的实施方法 | |
| Clark et al. | Microfluidic devices for imaging and manipulation of C. elegans | |
| Wang et al. | A fully automated robotic system for three-dimensional cell rotation | |
| US20140166486A1 (en) | Sperm separation devices and associated methods | |
| Andika | Enhancing Students' Interest In Learning About Zakat in Islamic Religious Education Through Problem Based Learning Methods At Class VI Students of SDN 20 Sitiung | |
| Arai et al. | Synchronized laser micromanipulation of microtools for assembly of microbeads and indirect manipulation of microbe | |
| GB1391053A (en) | Device for the extraction of blood | |
| CHANG et al. | Single cell isolation and pick up from the root tip of Arabidopsis | |
| Mofadel et al. | Bull sperm rheotaxis and kinematics in microfluidic channels with different heights |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |