AR044009A1 - PHARMACEUTICAL COMBINATION INCLUDING ELETRIPTAN AND SODIUM BICARBONATE - Google Patents
PHARMACEUTICAL COMBINATION INCLUDING ELETRIPTAN AND SODIUM BICARBONATEInfo
- Publication number
- AR044009A1 AR044009A1 ARP040101192A ARP040101192A AR044009A1 AR 044009 A1 AR044009 A1 AR 044009A1 AR P040101192 A ARP040101192 A AR P040101192A AR P040101192 A ARP040101192 A AR P040101192A AR 044009 A1 AR044009 A1 AR 044009A1
- Authority
- AR
- Argentina
- Prior art keywords
- sodium bicarbonate
- eletriptan
- pharmaceutical combination
- combination including
- prevention
- Prior art date
Links
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 title abstract 4
- OTLDLQZJRFYOJR-LJQANCHMSA-N eletriptan Chemical compound CN1CCC[C@@H]1CC1=CN=C2[C]1C=C(CCS(=O)(=O)C=1C=CC=CC=1)C=C2 OTLDLQZJRFYOJR-LJQANCHMSA-N 0.000 title abstract 3
- 229960002472 eletriptan Drugs 0.000 title abstract 3
- 229910000030 sodium bicarbonate Inorganic materials 0.000 title abstract 2
- 235000017557 sodium bicarbonate Nutrition 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 abstract 3
- 208000019695 Migraine disease Diseases 0.000 abstract 2
- 206010027599 migraine Diseases 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003521 serotonin 5-HT1 receptor agonist Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Combinación de a) eletriptan, o una de sus sales farmacéuticamente aceptables, y b) bicarbonato de sodio. La combinación proporciona una absorción rápida de eletriptan cuando se toma por vía oral. La combinación es útil para el tratamiento o la prevención de una enfermedad para la que es indicado un agente agonista de 5-HT1, particularmente en el tratamiento de una migraña o para la prevención de una recurrencia de migraña. Composición farmacéutica, uso y método de tratamiento o prevención.Combination of a) eletriptan, or a pharmaceutically acceptable salt thereof, and b) sodium bicarbonate. The combination provides rapid absorption of eletriptan when taken orally. The combination is useful for the treatment or prevention of a disease for which a 5-HT1 agonist agent is indicated, particularly in the treatment of a migraine or for the prevention of a migraine recurrence. Pharmaceutical composition, use and method of treatment or prevention.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0308469A GB0308469D0 (en) | 2003-04-11 | 2003-04-11 | Pharmaceutical combination |
| GB0312479A GB0312479D0 (en) | 2003-05-30 | 2003-05-30 | Pharmaceutical combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR044009A1 true AR044009A1 (en) | 2005-08-24 |
Family
ID=33161221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040101192A AR044009A1 (en) | 2003-04-11 | 2004-04-07 | PHARMACEUTICAL COMBINATION INCLUDING ELETRIPTAN AND SODIUM BICARBONATE |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1615635A1 (en) |
| JP (1) | JP2006522790A (en) |
| AR (1) | AR044009A1 (en) |
| BR (1) | BRPI0409127A (en) |
| CA (1) | CA2521902A1 (en) |
| MX (1) | MXPA05010070A (en) |
| NL (1) | NL1025908C2 (en) |
| PA (1) | PA8599901A1 (en) |
| PE (1) | PE20050086A1 (en) |
| TW (1) | TW200423929A (en) |
| UY (1) | UY28260A1 (en) |
| WO (1) | WO2004089365A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009142771A2 (en) * | 2008-05-22 | 2009-11-26 | Plus Chemicals, S.A. | Salts of (r)-5-(2-phenylsulphonylethenyl)-3-(n- methylpyrrolidin-2-ylmethyl)-1h-indole, 5-bromo-3-[(r)-1- methyl-pyrrolidin-2- ylmethyl]-1h-indole and of eletriptan |
| IT1393700B1 (en) | 2009-04-22 | 2012-05-08 | F S I Fabbrica Italiana Sint | SYNTHESIS OF 3 - {[(2R) -1-METHYLPYROLIDIN-2-IL] METHYL} -5- [2- (PHENILSULFONYL) ETYL] -1H-INDOL |
| JP6878021B2 (en) * | 2016-02-02 | 2021-05-26 | 第一三共ヘルスケア株式会社 | Pharmaceutical composition containing triptan and ascorbic acid |
| CR20210061A (en) * | 2018-07-03 | 2021-03-18 | Axsome Therapeutics Inc | PHARMACEUTICAL COMPOSITIONS INCLUDING MELOXICAM |
| MY198967A (en) * | 2019-02-06 | 2023-10-05 | Axsome Therapeutics Inc | Pharmaceutical compositions comprising meloxicam |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1197038B (en) * | 1986-08-01 | 1988-11-25 | Zambon Spa | PHARMACEUTICAL COMPOSITION WITH ANALGESIC ACTIVITY |
| US5607951A (en) | 1990-10-15 | 1997-03-04 | Pfizer Inc | Indole derivatives |
| IT1272149B (en) * | 1993-03-26 | 1997-06-11 | Zambon Spa | PHARMECEUTICAL COMPOSITION WITH ANALGESIC ACTIVITY |
| GB9417310D0 (en) | 1994-08-27 | 1994-10-19 | Pfizer Ltd | Therapeutic agents |
| US6488961B1 (en) | 1996-09-20 | 2002-12-03 | Ethypharm, Inc. | Effervescent granules and methods for their preparation |
| GB9704524D0 (en) * | 1997-03-05 | 1997-04-23 | Smithkline Beecham Plc | Composition |
| GB9816556D0 (en) | 1998-07-30 | 1998-09-30 | Pfizer Ltd | Therapy |
| GB9825988D0 (en) | 1998-11-27 | 1999-01-20 | Pfizer Ltd | Indole derivatives |
| CO5261541A1 (en) * | 1999-05-14 | 2003-03-31 | Pfizer Prod Inc | COMBINATION THERAPY FOR THE TREATMENT OF MIGRANA |
| GB0018968D0 (en) | 2000-08-02 | 2000-09-20 | Pfizer Ltd | Particulate composition |
| GB0105131D0 (en) * | 2001-03-01 | 2001-04-18 | Pfizer Ltd | Compositions having improved bioavailability |
| GB0129117D0 (en) * | 2001-12-05 | 2002-01-23 | Glaxo Group Ltd | Pharmaceutical composition |
| EP1594470A4 (en) * | 2003-02-19 | 2007-10-17 | Biovail Lab Int Srl | Rapid absorption selective 5-ht agonist formulations |
-
2004
- 2004-03-31 WO PCT/IB2004/001115 patent/WO2004089365A1/en not_active Ceased
- 2004-03-31 MX MXPA05010070A patent/MXPA05010070A/en active IP Right Grant
- 2004-03-31 CA CA002521902A patent/CA2521902A1/en not_active Abandoned
- 2004-03-31 JP JP2006506461A patent/JP2006522790A/en active Pending
- 2004-03-31 EP EP04724671A patent/EP1615635A1/en not_active Withdrawn
- 2004-03-31 BR BRPI0409127-2A patent/BRPI0409127A/en not_active IP Right Cessation
- 2004-04-06 UY UY28260A patent/UY28260A1/en not_active Application Discontinuation
- 2004-04-07 PE PE2004000356A patent/PE20050086A1/en not_active Application Discontinuation
- 2004-04-07 PA PA20048599901A patent/PA8599901A1/en unknown
- 2004-04-07 AR ARP040101192A patent/AR044009A1/en unknown
- 2004-04-08 NL NL1025908A patent/NL1025908C2/en not_active IP Right Cessation
- 2004-04-09 TW TW093109936A patent/TW200423929A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004089365A1 (en) | 2004-10-21 |
| NL1025908C2 (en) | 2005-11-22 |
| BRPI0409127A (en) | 2006-03-28 |
| CA2521902A1 (en) | 2004-10-21 |
| PA8599901A1 (en) | 2005-02-04 |
| PE20050086A1 (en) | 2005-03-01 |
| NL1025908A1 (en) | 2004-10-13 |
| TW200423929A (en) | 2004-11-16 |
| MXPA05010070A (en) | 2005-11-23 |
| JP2006522790A (en) | 2006-10-05 |
| EP1615635A1 (en) | 2006-01-18 |
| UY28260A1 (en) | 2004-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |