AR065533A1 - Metodos de transcripcion, constructos de adn de repeticion en tandem, productores de proteinas que atacan geminivirus patogenos de plantas a traves de la interrupcion de los factores de transcripcion esenciales de los agentes patogenos - Google Patents
Metodos de transcripcion, constructos de adn de repeticion en tandem, productores de proteinas que atacan geminivirus patogenos de plantas a traves de la interrupcion de los factores de transcripcion esenciales de los agentes patogenosInfo
- Publication number
- AR065533A1 AR065533A1 ARP080102219A ARP080102219A AR065533A1 AR 065533 A1 AR065533 A1 AR 065533A1 AR P080102219 A ARP080102219 A AR P080102219A AR P080102219 A ARP080102219 A AR P080102219A AR 065533 A1 AR065533 A1 AR 065533A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- trs
- plants
- zfp
- derivatives
- Prior art date
Links
- 241000702463 Geminiviridae Species 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108020004414 DNA Proteins 0.000 title abstract 2
- 230000001717 pathogenic effect Effects 0.000 title abstract 2
- 230000035897 transcription Effects 0.000 title abstract 2
- 238000013518 transcription Methods 0.000 title abstract 2
- 108091023040 Transcription factor Proteins 0.000 title 1
- 102000040945 Transcription factor Human genes 0.000 title 1
- 244000052769 pathogen Species 0.000 title 1
- SIOXPEMLGUPBBT-UHFFFAOYSA-N picolinic acid Chemical compound OC(=O)C1=CC=CC=N1 SIOXPEMLGUPBBT-UHFFFAOYSA-N 0.000 abstract 13
- 241000700605 Viruses Species 0.000 abstract 6
- 101710185494 Zinc finger protein Proteins 0.000 abstract 6
- 102100023597 Zinc finger protein 816 Human genes 0.000 abstract 6
- 229940081066 picolinic acid Drugs 0.000 abstract 6
- 239000003443 antiviral agent Substances 0.000 abstract 3
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- DGMPVYSXXIOGJY-UHFFFAOYSA-N Fusaric acid Chemical compound CCCCC1=CC=C(C(O)=O)N=C1 DGMPVYSXXIOGJY-UHFFFAOYSA-N 0.000 abstract 2
- 108700005090 Lethal Genes Proteins 0.000 abstract 2
- 230000000840 anti-viral effect Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108010026552 Proteome Proteins 0.000 abstract 1
- 108091081062 Repeated sequence (DNA) Proteins 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 230000001174 ascending effect Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 abstract 1
- 108010069125 picolinic acid carboxylase Proteins 0.000 abstract 1
- 230000029279 positive regulation of transcription, DNA-dependent Effects 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 230000029812 viral genome replication Effects 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
- C12N15/8238—Externally regulated expression systems chemically inducible, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
- C12N15/8239—Externally regulated expression systems pathogen inducible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
- C12N15/8263—Ablation; Apoptosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Métodos y composiciones referidas al tratamiento, al control o la inhibicion de Geminivirus, mediante la reduccion o la inhibicion del crecimiento de los Geminivirus (GV) que emplean un compuesto que tiene la estructura siguiente (1), o una salfarmacéuticamente aceptables de ese compuesto, caracterizado porque a R1, R2, R3 y R4 se seleccionan del grupo consistente en un grupo carboxilo, un grupo metilo, un grupo etilo, un grupo propilo, un grupo isopropilo, un grupo butilo, un grupoisobutilo, un grupo butilo secundario, un grupo butilo terciario, un grupo pentilo, un grupo isopentilo, un grupo neopentilo, fluor, cloro, bromo, yodo y hidrogeno. Se brinda varias clases de compuestos antivirosicos que se puede utilizar odesintegrar geminivirus, tales como los geminivirus africanos del mosaico de la casava (ACMV) y los geminivirus del Este de África del mosaico de la casava (EAMGV), a través del ataque del dominio de dedos de zinc [Zn2+]-[CCHC] o de variaciones deél, el tal dominio estando presente en la nucelocápside u otras ZFP virosicas. A los agentes antivirosicos se los diseno para usárselos en plantas infectadas por virus patogenos. Estos agentes antivirosicos comprenden el Ácido Picolínico (PA) yderivados de él. Los agentes pueden ligar de manera coordinada el Zn2+ a la proteína del virus y expulsar el Zn2+ de la ZFP (proteína dedo de Zinc) o se pueden ligar al Zn2+ y formar un complejo ternario con la ZFP [PA-Zn2+-ZFP] virosica. Además,también se desarrollo un sistema disenado para detectar e identificar derivados antivirosicos de ácido picolínico contra los GV, basado sobre la capacidad de estos derivados para reaccionar e interrumpir los motivos de CCHC (o una variacion deellos) en la ZFP de los GV. Los agentes y métodos antivirosicos que comprenden el empleo de ácido picolínico, ácido fusárico y derivados de estos agregados en forma exogena, también se pueden emplear para prevenir, controlar o eliminar cualquierotrovirus de plantas que contenga ZFP esenciales en el proteoma o que utilice las ZFP de la célula hospedante para la activacion transcripcional. Además, se da a conocer una tecnología de Secuencia Repetida de Tandem (TRS), denotada como método deConstructo de TRS en caja, para la produccion de plantas singénicas con resistencia aumentada a los virus. Esta tecnología incorpora, en el genoma de la planta, secuencias de ADN estables repetidas en tandem, que codifican enzimas que puedenproducir PA o derivados de él. La produccion aumentada de PA o derivados de él. La produccion aumentada de PA endogeno por la Carboxilasa de Ácido Picolínico, inducida por un promotor de proteína virosica por TRS que está presente en el Constructode TRS en caja, puede inactivar e interrumpir la ZFP virosicas necesarias para la replicacion de los virus. Las plantas singénicas en las que se introdujo el Constructo de TRS en caja para conferir resistencia a los virus son genéticamente establesy fértiles. Las plantas singénicas con TRS producen flores y semillas que se puede volver a plantar para producir nuevas plantas singénicas con TRS que son resistentes a los virus. Por anadidura, las plantas singénicas con TRS están sujetas a laspresiones evolutivas del ambiente, tal como si fueran la contraparte de tipo silvestre. Más aun; dado que no contienen agentes agregados en forma exogena o endogena, son comestibles sin que haya que hacerles más modificaciones. Reivindicacion 1: Unmétodo de transcripcion, caracterizado porque comprende transcribir genes letales que precisan una secuencia específica de promotor inducible por ADN, que está presente en la unidad de caja que tiene elevada afinidad por un (unos) factor(es) detrascripcion virosica, la secuencia de ADN del promotor está presente en sentido ascendente respecto de los genes letales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/051,080 US20090241222A1 (en) | 2008-03-19 | 2008-03-19 | Tandem reapeat dna constructs producing proteins that attack plant pathogenic viruses, fungi, and bacteria by disrupting transcription factors essential for replication thereof in plants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR065533A1 true AR065533A1 (es) | 2009-06-17 |
Family
ID=40845768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080102219A AR065533A1 (es) | 2008-03-19 | 2008-05-27 | Metodos de transcripcion, constructos de adn de repeticion en tandem, productores de proteinas que atacan geminivirus patogenos de plantas a traves de la interrupcion de los factores de transcripcion esenciales de los agentes patogenos |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US20090241222A1 (es) |
| AR (1) | AR065533A1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109964278A (zh) * | 2017-03-30 | 2019-07-02 | 艾腾怀斯股份有限公司 | 通过并行评估分类器输出校正第一分类器中的误差的系统和方法 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2795480C (en) | 2010-04-06 | 2021-10-26 | Vrije Universiteit Brussel | Specific delivery of agrochemicals |
| WO2017136895A1 (en) * | 2016-02-10 | 2017-08-17 | Queensland University Of Technology | Constructs and methods for conferring virus resistance |
| WO2021209275A1 (en) * | 2020-04-12 | 2021-10-21 | Novoscope Ip Limited | Particles, dna & rna |
| US12268676B2 (en) | 2021-01-20 | 2025-04-08 | Indian Institute Of Science | Antiviral applications of picolinic acid and its derivatives |
| CN112899301B (zh) * | 2021-01-29 | 2023-04-11 | 中国热带农业科学院热带生物技术研究所 | 一种木薯普通花叶病毒诱导的基因沉默系统及其应用 |
| US20240307514A1 (en) * | 2021-07-02 | 2024-09-19 | Dignity Health | Modulation of acmsd protein expression |
-
2008
- 2008-03-19 US US12/051,080 patent/US20090241222A1/en not_active Abandoned
- 2008-05-27 AR ARP080102219A patent/AR065533A1/es unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109964278A (zh) * | 2017-03-30 | 2019-07-02 | 艾腾怀斯股份有限公司 | 通过并行评估分类器输出校正第一分类器中的误差的系统和方法 |
| CN109964278B (zh) * | 2017-03-30 | 2023-06-27 | 艾腾怀斯股份有限公司 | 通过并行评估分类器输出校正第一分类器中的误差 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090241222A1 (en) | 2009-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR065533A1 (es) | Metodos de transcripcion, constructos de adn de repeticion en tandem, productores de proteinas que atacan geminivirus patogenos de plantas a traves de la interrupcion de los factores de transcripcion esenciales de los agentes patogenos | |
| Yang et al. | Suppression of methylation-mediated transcriptional gene silencing by βC1-SAHH protein interaction during geminivirus-betasatellite infection | |
| Lengyel et al. | Convergent evolution of seed dispersal by ants, and phylogeny and biogeography in flowering plants: a global survey | |
| Poretsky et al. | Differential activities of maize plant elicitor peptides as mediators of immune signaling and herbivore resistance | |
| Shaw et al. | Coilin, the signature protein of Cajal bodies, differentially modulates the interactions of plants with viruses in widely different taxa | |
| NO20090057L (no) | Regulatoriske nukleinsyre elementer | |
| NZ586238A (en) | Methods and compositions for immunizing pigs against porcine circovirus | |
| AR104024A1 (es) | Métodos y composiciones para la introgresión acelerada de rasgos | |
| AR117629A2 (es) | Dominio de activación potente | |
| AR118306A1 (es) | 3-fenilisoxazolin-5-carboxamidas de ésteres de ácido ciclopentenilcarboxílico que contienen s de acción herbicida | |
| MX2011012312A (es) | Vacuna universal para influenza basada en virus vaccinia ankara (mva) modificado recombinante. | |
| ES2654613T3 (es) | Promotores para una expresión aumentada de proteínas en meningococos | |
| DE602007012343D1 (de) | Antimykotische polypeptide | |
| WO2013030176A3 (en) | Live attenuated influenza virus | |
| BR112018005629A2 (pt) | promotor de planta e 3' utr para expressão de transgene | |
| Jansen et al. | Stress: the way of life | |
| WO2009129208A8 (en) | Compositions and methods of inducing endoplasmic reticulum stress reponse | |
| MX2013001783A (es) | Variantes de defensina y metodos de uso. | |
| AR065746A1 (es) | Constructos de adn de repeticion en tandem, productores de proteinas que atacan virus, hongos y bacterias patogenos de plantas a traves de la interrupcion de los factores de transcripcion esenciales para que los mencionados agentes patogenos hagan su replicacion en las plantas | |
| AR065534A1 (es) | Constructos de adn de repeticion en tandem, productores de proteinas que atacan virus, hongos y bacterias patogenos de plantas a traves de la interrupcion de los factores de transcripcion esenciales para que los mencionados agentes patogenos hagan su replicacion en las plantas | |
| BR112012009044A2 (pt) | Molécula de ácido nucléico isolada, cassete de expressão, vetor, célula vegetal, planta, semente transgênica, método para expressão de um polinucleotídeo em uma planta ou célula vegetal e método para expressão de um polinucleotídeo, preferencialmente em tecidos somáticos de óvulo de uma planta | |
| BR112015017788A2 (pt) | Construto de dna, método para produzir uma planta, método de detecção da presença de uma molécula de ácido nucleico, par de iniciadores de polinucleotídio, evento de milho, método de detecção da presença do dna e kit para detectar ácidos nucleicos | |
| AR072157A1 (es) | Metodos y medios para aumentar la eficacia en el uso de agua en plantas | |
| MX2021000949A (es) | Nueva cepa de virus atenuada y su uso como una vacuna. | |
| BR112016015875A2 (pt) | Elementos intensificadores de cpmv |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |