AR100763A1 - SISTEMA DE LIBERACIÓN DE AGROQUÍMICOS A BASE DE HÍBRIDOS DE PEG-DENDRÓN ANFIFÍLICO QUE RESPONDE A ENZIMAS O AL pH - Google Patents
SISTEMA DE LIBERACIÓN DE AGROQUÍMICOS A BASE DE HÍBRIDOS DE PEG-DENDRÓN ANFIFÍLICO QUE RESPONDE A ENZIMAS O AL pHInfo
- Publication number
- AR100763A1 AR100763A1 ARP150100557A ARP150100557A AR100763A1 AR 100763 A1 AR100763 A1 AR 100763A1 AR P150100557 A ARP150100557 A AR P150100557A AR P150100557 A ARP150100557 A AR P150100557A AR 100763 A1 AR100763 A1 AR 100763A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydrophobic
- agrochemical
- micelle
- dendron
- release system
- Prior art date
Links
- 239000003905 agrochemical Substances 0.000 title abstract 7
- 102000004190 Enzymes Human genes 0.000 title abstract 3
- 108090000790 Enzymes Proteins 0.000 title abstract 3
- 230000002209 hydrophobic effect Effects 0.000 abstract 6
- 239000000693 micelle Substances 0.000 abstract 5
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 230000001419 dependent effect Effects 0.000 abstract 2
- 239000003002 pH adjusting agent Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
- C08G83/004—After treatment of dendrimers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Enzymes And Modification Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicinal Preparation (AREA)
Abstract
Reivindicación 1: Un sistema de liberación hibrido anfifílico en forma micelar para la liberación de agroquímicos, que comprende un polímero de polietilenglicol hidrofílico (PEG) conjugado con un dendrón hidrofóbico, donde el dendrón comprende al menos un grupo terminal hidrofóbico dependiente del pH o enzimáticamente escindible que se une covalentemente con el dendrón, en donde dicha micela comprende un agroquímico ya sea como parte del grupo terminal hidrofóbico o encapsulado dentro de la micela o ambos y en donde dicha micela se desensambla para liberar el agroquímico después de la escisión enzimática o dependiente del pH de dicho grupo terminal hidrofóbico. Reivindicación 16: El sistema de liberación híbrido de acuerdo con la reivindicación 15, en donde cada generación del dendrón se deriva de un compuesto seleccionado del grupo que consiste en HS-CH₂-CH₂-OH, HS-(CH₂)₁₋₃-CO₂H y HS-CH₂-CH(OH)-CH₂-OH. Reivindicación 46: Un método de liberación del agroquímico sistema hibrido anfifílico de acuerdo con cualquiera de las reivindicaciones precedentes, que comprende la etapa de puesta en contacto de una planta o los alrededores de la planta con el sistema de liberación híbrido anfifílico y una enzima o un agente de ajuste del pH en una cantidad efectiva para inducir la escisión del grupo terminal hidrofóbico escindible, desensamblando así dicha micela. Reivindicación 47: Un kit para liberar el agroquímico sistema híbrido anfifílico de acuerdo con cualquiera de las reivindicaciones precedentes, que comprende en un compartimiento el agroquímico sistema híbrido anfifílico y en un segundo compartimiento una enzima o un agente de ajuste del pH capaz de hidrolizar el grupo terminal hidrofóbico escindible de modo de desensamblar dicha micela.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462047679P | 2014-09-09 | 2014-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR100763A1 true AR100763A1 (es) | 2016-11-02 |
Family
ID=55458417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150100557A AR100763A1 (es) | 2014-09-09 | 2015-02-25 | SISTEMA DE LIBERACIÓN DE AGROQUÍMICOS A BASE DE HÍBRIDOS DE PEG-DENDRÓN ANFIFÍLICO QUE RESPONDE A ENZIMAS O AL pH |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20170245492A1 (es) |
| EP (1) | EP3190880A4 (es) |
| CN (1) | CN107072193A (es) |
| AR (1) | AR100763A1 (es) |
| AU (1) | AU2015313797A1 (es) |
| BR (1) | BR112017004738A2 (es) |
| CA (1) | CA2960592A1 (es) |
| IL (1) | IL250845A0 (es) |
| WO (1) | WO2016038596A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10869939B2 (en) | 2015-08-03 | 2020-12-22 | Ramot At Tel-Aviv University Ltd. | Delivery system in micellar form having modular spectral response based on enzyme-responsive amphiphilic PEG-dendron hybrid polymers |
| KR20190051656A (ko) * | 2017-11-07 | 2019-05-15 | 삼성전자주식회사 | 식각 조성물, 실리콘 질화막의 식각 방법, 및 반도체 소자의 제조 방법 |
| CN108078924B (zh) * | 2017-12-07 | 2020-06-02 | 同济大学 | 一种聚乙二醇修饰的具有pH响应性的高载药量纳米胶束或囊泡的制备方法 |
| CN109453364B (zh) * | 2018-09-30 | 2021-10-15 | 郑州大学第一附属医院 | 一种双重响应性纳米颗粒及其在肿瘤抑制中的应用 |
| US20220183277A1 (en) * | 2019-03-22 | 2022-06-16 | Kansas State University Research Foundation | Lipid encasing amphipathic peptides |
| AU2020380081B2 (en) | 2019-11-08 | 2025-05-08 | Donaghys Limited | A composition and related methods of manufacture and use |
| CN113801508B (zh) * | 2020-06-12 | 2022-08-30 | 威高集团有限公司 | 一种具有磷酸酶响应功能的抗菌涂层、具有抗菌涂层的功能材料及其制备方法 |
| CN114441458B (zh) * | 2021-05-24 | 2023-06-09 | 中国科学院海洋研究所 | 一种zif材料在抑制模拟酶中的应用 |
| CN113637657B (zh) * | 2021-08-05 | 2024-01-30 | 云南师范大学 | 一种羧酸酯酶CarCB2及其全细胞催化剂和应用 |
| CN114158551B (zh) * | 2021-11-22 | 2022-09-30 | 定远众邦生物工程有限公司 | 一种对弱碱环境快速响应的纳米农药制剂、制备方法及其应用 |
| WO2024052920A1 (en) * | 2022-09-08 | 2024-03-14 | Ramot At Tel-Aviv University Ltd. | Programmable stimuli-responsive polymeric formulations |
| US20240180838A1 (en) * | 2022-12-05 | 2024-06-06 | Rutgers, The State University Of New Jersey | Nanoparticle (np) compositions and methods of use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI955320A7 (fi) * | 1994-03-07 | 1995-11-24 | Univ Michigan | Bioaktiivisia ja/tai kohdennettuja dendriimikonjugaatteja |
| AU2002303146A1 (en) * | 2001-03-22 | 2002-10-08 | The Administrators Of The Tulane Educational Fund | Biaryl monomers and dendritic polymers derived therefrom |
| US20050226934A1 (en) * | 2001-09-28 | 2005-10-13 | Solubest Ltd. | Inclusion complexes of active compounds in acrylate (co)polymers and methods for their production |
| AU2003256038A1 (en) * | 2002-08-30 | 2004-03-19 | Ramot At Tel Aviv University Ltd. | Self-immolative dendrimers releasing many active moieties upon a single activating event |
| US7985424B2 (en) * | 2004-04-20 | 2011-07-26 | Dendritic Nanotechnologies Inc. | Dendritic polymers with enhanced amplification and interior functionality |
| US20060269480A1 (en) * | 2005-05-31 | 2006-11-30 | Ramot At Tel Aviv University Ltd. | Multi-triggered self-immolative dendritic compounds |
| WO2008079677A2 (en) * | 2006-12-20 | 2008-07-03 | Arkema Inc. | Polymer encapsulation and/or binding |
| WO2011053605A1 (en) * | 2009-10-26 | 2011-05-05 | Dendritic Nanotechnologies, Inc. | Peham dendrimers for use in agriculture |
| US8703907B2 (en) * | 2010-05-05 | 2014-04-22 | Prolynx Llc | Controlled drug release from dendrimers |
| EP2678042B1 (en) * | 2011-02-23 | 2018-05-09 | The Board of Trustees of the University of Illionis | Amphiphilic dendron-coils, micelles thereof and uses |
| EP2793953B1 (en) * | 2011-12-21 | 2019-12-04 | The Regents of The University of California | Telodendrimers with enhanced drug delivery |
| CN106687142A (zh) * | 2014-09-09 | 2017-05-17 | 雷蒙特亚特特拉维夫大学有限公司 | 基于酶响应性两亲性peg‑树枝化基元杂化物的胶束递送系统 |
-
2015
- 2015-02-25 AR ARP150100557A patent/AR100763A1/es unknown
- 2015-02-25 BR BR112017004738A patent/BR112017004738A2/pt not_active Application Discontinuation
- 2015-02-25 AU AU2015313797A patent/AU2015313797A1/en not_active Abandoned
- 2015-02-25 CA CA2960592A patent/CA2960592A1/en not_active Abandoned
- 2015-02-25 CN CN201580060843.3A patent/CN107072193A/zh active Pending
- 2015-02-25 US US15/509,946 patent/US20170245492A1/en not_active Abandoned
- 2015-02-25 WO PCT/IL2015/050213 patent/WO2016038596A1/en not_active Ceased
- 2015-02-25 EP EP15839979.0A patent/EP3190880A4/en not_active Withdrawn
-
2017
- 2017-02-28 IL IL250845A patent/IL250845A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015313797A1 (en) | 2017-03-30 |
| IL250845A0 (en) | 2017-04-30 |
| WO2016038596A1 (en) | 2016-03-17 |
| EP3190880A4 (en) | 2018-04-18 |
| EP3190880A1 (en) | 2017-07-19 |
| US20170245492A1 (en) | 2017-08-31 |
| CN107072193A (zh) | 2017-08-18 |
| BR112017004738A2 (pt) | 2017-12-05 |
| CA2960592A1 (en) | 2016-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |