AT207046B - Method of sterilization - Google Patents

Method of sterilization

Info

Publication number
AT207046B
AT207046B AT673758A AT673758A AT207046B AT 207046 B AT207046 B AT 207046B AT 673758 A AT673758 A AT 673758A AT 673758 A AT673758 A AT 673758A AT 207046 B AT207046 B AT 207046B
Authority
AT
Austria
Prior art keywords
sep
xxx
ethylene oxide
methyl formate
sterilization
Prior art date
Application number
AT673758A
Other languages
German (de)
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Application granted granted Critical
Publication of AT207046B publication Critical patent/AT207046B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A61L2/206—Ethylene oxide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Description

  

   <Desc/Clms Page number 1> 
 



  Verfahren zum Sterilisieren 
 EMI1.1 
 
 EMI1.2 
 
<tb> 
<tb> 



  Konzentration <SEP> in <SEP> g/m3
<tb> 500 <SEP> 650 <SEP> 750 <SEP> 850 <SEP> 1000
<tb> Äthylenoxyd <SEP> xx <SEP> x <SEP> x <SEP> 0 <SEP> 0
<tb> 500 <SEP> Äthylenoxyd <SEP> +
<tb> 50% <SEP> Methylformiat <SEP> x <SEP> o <SEP> o <SEP> o <SEP> o <SEP> 
<tb> Methylformiat <SEP> xxx <SEP> xx <SEP> x <SEP> x <SEP> o
<tb> 
 

 <Desc/Clms Page number 2> 

 Zeichenerklärung: Überlebende Keime / cm2 Plattenoberfläche xxx über 2000 xx 500-2000 x unter 500 o steril   Beispiel 2 : Testorganismus :   Staphylococcus var. aureus Rosenbach
Nährsubstrat, Bestimmung der Keimzahl und Beobachtungszeitraum wie in Beispiel l. 
 EMI2.1 
 
<tb> 
<tb> 



  Konzentration <SEP> in <SEP> g/m3
<tb> 350 <SEP> 500 <SEP> 650 <SEP> 750 <SEP> 850 <SEP> 1000 <SEP> 
<tb> Äthylenoxyd <SEP> xxx <SEP> xxx <SEP> xx <SEP> xx <SEP> x <SEP> x
<tb> Propylenoxd <SEP> xxx <SEP> xxx <SEP> xx <SEP> xx <SEP> x <SEP> x
<tb> Methylbromid <SEP> xxx <SEP> xxx <SEP> xxx <SEP> xx <SEP> xx <SEP> x
<tb> Methylformiat <SEP> xxx <SEP> xx <SEP> xx, <SEP> xx <SEP> x <SEP> x
<tb> 1 <SEP> VoL-Teil <SEP> Äthylenoxyd <SEP> + <SEP> 
<tb> 2 <SEP> Vol-Teile <SEP> Methylbromid <SEP> xxx <SEP> xxx <SEP> xx <SEP> x <SEP> 0 <SEP> 0
<tb> 40 <SEP> Äthylenoxyd <SEP> +
<tb> 60% <SEP> Propylenoxyd <SEP> xxx <SEP> xxx <SEP> xx <SEP> x <SEP> 0 <SEP> 0
<tb> 50% <SEP> Äthylenoxyd <SEP> + <SEP> 
<tb> 500 <SEP> Methylformiat <SEP> xx <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0
<tb> 
   Zeichenerldärung :    xxx über 2000 xx 500- 2000 x unter 500
0 steril Beispiel 3:

   Testorganismus: E. coli
Nährsubstrat, Bestimmung der Keimzahl und Beobachtungszeitraum wie in Beispiel l. 
 EMI2.2 
 
<tb> 
<tb> 



  Konzentration <SEP> in <SEP> g/m3
<tb> 350 <SEP> 500 <SEP> ô50 <SEP> 750 <SEP> 850 <SEP> 1000
<tb> Äthylenoxyd <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> 0 <SEP> 0
<tb> Propylenoxyd <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> 0 <SEP> 0
<tb> Methylbromid <SEP> xxx <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> x
<tb> Methylformiat <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> x <SEP> x
<tb> 1 <SEP> Vol.-Teil <SEP> Äthylenoxyd <SEP> +
<tb> 2 <SEP> Vol.-Teile <SEP> Methylbromid <SEP> xx <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0
<tb> 400 <SEP> Äthylenoxyd <SEP> +
<tb> 60% <SEP> Propylenoxyd <SEP> xx <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0
<tb> 50% <SEP> Äthylenoxyd <SEP> +
<tb> 50% <SEP> Methylformiat <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0 <SEP> 0
<tb> 
 Kontrolle :

   über 2000 

 <Desc/Clms Page number 3> 

 
Die Beispiele lassen erkennen, dass die erfindungsgemässen Gemische entweder schon in geringerer Konzentration die gleiche Wirkung zeigen wie die einzelnen Komponenten, oder aber bei vergleichbarer Konzentration erheblich wirksamer sind. Ähnliches gilt gegenüber den bekannten Gemischen. 



    PATENTANSPRÜCHE :    
1. Verfahren zum Sterilisieren von Waren aller Art, dadurch gekennzeichnet, dass sie mit einem Gemisch von Äthylenoxyd und Methylformiat behandelt werden.



   <Desc / Clms Page number 1>
 



  Method of sterilization
 EMI1.1
 
 EMI1.2
 
<tb>
<tb>



  Concentration <SEP> in <SEP> g / m3
<tb> 500 <SEP> 650 <SEP> 750 <SEP> 850 <SEP> 1000
<tb> Ethylene oxide <SEP> xx <SEP> x <SEP> x <SEP> 0 <SEP> 0
<tb> 500 <SEP> ethylene oxide <SEP> +
<tb> 50% <SEP> methyl formate <SEP> x <SEP> o <SEP> o <SEP> o <SEP> o <SEP>
<tb> methyl formate <SEP> xxx <SEP> xx <SEP> x <SEP> x <SEP> o
<tb>
 

 <Desc / Clms Page number 2>

 Explanation of symbols: Surviving germs / cm2 plate surface xxx over 2000 xx 500-2000 x under 500 o sterile Example 2: Test organism: Staphylococcus var. Aureus Rosenbach
Nutrient substrate, determination of the number of germs and observation period as in Example 1.
 EMI2.1
 
<tb>
<tb>



  Concentration <SEP> in <SEP> g / m3
<tb> 350 <SEP> 500 <SEP> 650 <SEP> 750 <SEP> 850 <SEP> 1000 <SEP>
<tb> Ethylene oxide <SEP> xxx <SEP> xxx <SEP> xx <SEP> xx <SEP> x <SEP> x
<tb> Propylenoxd <SEP> xxx <SEP> xxx <SEP> xx <SEP> xx <SEP> x <SEP> x
<tb> methyl bromide <SEP> xxx <SEP> xxx <SEP> xxx <SEP> xx <SEP> xx <SEP> x
<tb> methyl formate <SEP> xxx <SEP> xx <SEP> xx, <SEP> xx <SEP> x <SEP> x
<tb> 1 <SEP> VoL part <SEP> Ethylene oxide <SEP> + <SEP>
<tb> 2 <SEP> parts by volume <SEP> methyl bromide <SEP> xxx <SEP> xxx <SEP> xx <SEP> x <SEP> 0 <SEP> 0
<tb> 40 <SEP> ethylene oxide <SEP> +
<tb> 60% <SEP> propylene oxide <SEP> xxx <SEP> xxx <SEP> xx <SEP> x <SEP> 0 <SEP> 0
<tb> 50% <SEP> ethylene oxide <SEP> + <SEP>
<tb> 500 <SEP> methyl formate <SEP> xx <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0
<tb>
   Explanation of signs: xxx over 2000 xx 500- 2000 x under 500
0 sterile Example 3:

   Test organism: E. coli
Nutrient substrate, determination of the number of germs and observation period as in Example 1.
 EMI2.2
 
<tb>
<tb>



  Concentration <SEP> in <SEP> g / m3
<tb> 350 <SEP> 500 <SEP> ô50 <SEP> 750 <SEP> 850 <SEP> 1000
<tb> Ethylene oxide <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> 0 <SEP> 0
<tb> propylene oxide <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> 0 <SEP> 0
<tb> methyl bromide <SEP> xxx <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> x
<tb> methyl formate <SEP> xx <SEP> xx <SEP> x <SEP> x <SEP> x <SEP> x
<tb> 1 <SEP> Part by volume <SEP> Ethylene oxide <SEP> +
<tb> 2 <SEP> parts by volume <SEP> methyl bromide <SEP> xx <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0
<tb> 400 <SEP> ethylene oxide <SEP> +
<tb> 60% <SEP> propylene oxide <SEP> xx <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0
<tb> 50% <SEP> ethylene oxide <SEP> +
<tb> 50% <SEP> methyl formate <SEP> xx <SEP> x <SEP> 0 <SEP> 0 <SEP> 0 <SEP> 0
<tb>
 Control:

   over 2000

 <Desc / Clms Page number 3>

 
The examples show that the mixtures according to the invention either show the same effect as the individual components in a lower concentration, or are considerably more effective at a comparable concentration. The same applies to the known mixtures.



    PATENT CLAIMS:
1. A method for sterilizing goods of all kinds, characterized in that they are treated with a mixture of ethylene oxide and methyl formate.

Claims (1)

2. Verfahren nach Anspruch 1, dadurch gekennzeichnet, dass ein Gemisch aus 40-60 Vol.-% Äthylenoxyd, Rest Methylformiat zur Anwendung gelangt. 2. The method according to claim 1, characterized in that a mixture of 40-60 vol .-% ethylene oxide, the remainder methyl formate is used.
AT673758A 1957-10-25 1958-09-25 Method of sterilization AT207046B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DED26717A DE1055759B (en) 1957-10-25 1957-10-25 Process for sterilizing with mixtures containing ethylene oxide

Publications (1)

Publication Number Publication Date
AT207046B true AT207046B (en) 1960-01-11

Family

ID=7038984

Family Applications (1)

Application Number Title Priority Date Filing Date
AT673758A AT207046B (en) 1957-10-25 1958-09-25 Method of sterilization

Country Status (5)

Country Link
AT (1) AT207046B (en)
CH (1) CH372136A (en)
DE (1) DE1055759B (en)
GB (1) GB844828A (en)
NL (1) NL99735C (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2037439A (en) * 1928-09-11 1936-04-14 Union Carbide & Carbon Corp Fumigant composition

Also Published As

Publication number Publication date
DE1055759B (en) 1959-04-23
CH372136A (en) 1963-09-30
NL99735C (en) 1961-11-15
GB844828A (en) 1960-08-17

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