AT283597B - Process for the preparation of adriamycin and adriamycinone - Google Patents

Process for the preparation of adriamycin and adriamycinone

Info

Publication number: AT283597B
Authority: AT; Austria
Prior art keywords: adriamycinone; adriamycin; preparation
Prior art date: 1968-04-12

Application number

AT347269A

Other languages

German (de)

Inventor

Federico Arcamone

Giovanni Franceschi

Sergio Penco

Original Assignee

Farmaceutici Italia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1968-04-12

Filing date

1969-04-10

Publication date

1970-08-10

1969-04-10 Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia

1970-08-10 Application granted granted Critical

1970-08-10 Publication of AT283597B publication Critical patent/AT283597B/en

Links

AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title 2
IBZGBXXTIGCACK-CWKPULSASA-N Adriamycinone Chemical compound C1[C@@](O)(C(=O)CO)C[C@H](O)C2=C1C(O)=C1C(=O)C(C=CC=C3OC)=C3C(=O)C1=C2O IBZGBXXTIGCACK-CWKPULSASA-N 0.000 title 1
229940009456 adriamycin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT347269A 1968-04-12 1969-04-10 Process for the preparation of adriamycin and adriamycinone AT283597B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT1515968		1968-04-12

Publications (1)

Publication Number	Publication Date
AT283597B true AT283597B (en)	1970-08-10

Family

ID=11146828

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT347269A AT283597B (en)	1968-04-12	1969-04-10	Process for the preparation of adriamycin and adriamycinone

Country Status (13)

Country	Link
AT (1)	AT283597B (en)
BE (1)	BE731398A (en)
CH (1)	CH518250A (en)
DE (1)	DE1917874C3 (en)
DK (1)	DK126987B (en)
ES (1)	ES365907A1 (en)
FR (1)	FR2007443A1 (en)
GB (1)	GB1217133A (en)
IL (1)	IL31966A (en)
NL (1)	NL145536B (en)
NO (1)	NO133271C (en)
SE (1)	SE359293B (en)
YU (1)	YU34389B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986000073A1 (en) *	1984-06-14	1986-01-03	BIOGAL Gyógyszergyár	Process for preparing adriamycine and halide salts thereof

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2160716A1 (en) *	1971-11-23	1973-07-06	Rhone Poulenc Sa	Antibiotics duborimycin and 27706rp - by reduction of daunorubicin and adriamycin
FR2135221A1 (en) *	1971-05-04	1972-12-15	Farmaceutici Italia	Doxorubicin 14-esters prepn - by treating 14-bromodaunomycin with a salt of the corresp acid
US4201773A (en) *	1978-07-26	1980-05-06	The United States Of America As Represented By The Department Of Health, Education And Welfare	7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
US4348388A (en) *	1980-04-02	1982-09-07	G.D. Searle & Co.	11-Amino-11-deoxydaunorubicin and analogs
GB2125030B (en) *	1982-08-13	1986-11-26	Erba Farmitalia	Naphthacenequinone synthesis
GB2169285A (en) *	1985-01-05	1986-07-09	Erba Farmitalia	4'-Deoxydoxorubicin-14-esters
GB2169286A (en) *	1985-01-05	1986-07-09	Erba Farmitalia	4'-Deoxy-4'-halodoxorubicin-14-esters
GB2169284A (en) *	1985-01-05	1986-07-09	Erba Farmitalia	4'-Epidoxorubicin-14-esters
JP3112342B2 (en) *	1992-06-10	2000-11-27	協和醗酵工業株式会社	New compound UCE6
DK0648503T3 (en) *	1993-09-22	2000-10-02	Hoechst Ag	Pro-prodrugs, their manufacture and use
GB9416007D0 (en) *	1994-08-08	1994-09-28	Erba Carlo Spa	Anthracyclinone derivatives
EP2824108B8 (en) *	2012-03-06	2017-07-12	Tianjin Hemay Oncology Pharmaceutical Co., Ltd.	Tetracyclic anthraquinone derivatives

1969
- 1969-03-28 NL NL696904844A patent/NL145536B/en not_active IP Right Cessation
- 1969-04-07 YU YU858/69A patent/YU34389B/en unknown
- 1969-04-07 IL IL31966A patent/IL31966A/en unknown
- 1969-04-08 DE DE1917874A patent/DE1917874C3/en not_active Expired
- 1969-04-10 AT AT347269A patent/AT283597B/en not_active IP Right Cessation
- 1969-04-10 SE SE05048/69A patent/SE359293B/xx unknown
- 1969-04-10 NO NO1464/69A patent/NO133271C/no unknown
- 1969-04-10 DK DK197469AA patent/DK126987B/en unknown
- 1969-04-10 FR FR6911030A patent/FR2007443A1/fr active Pending
- 1969-04-11 BE BE731398D patent/BE731398A/en not_active IP Right Cessation
- 1969-04-11 CH CH557169A patent/CH518250A/en not_active IP Right Cessation
- 1969-04-11 GB GB08719/69A patent/GB1217133A/en not_active Expired
- 1969-04-11 ES ES365907A patent/ES365907A1/en not_active Expired

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986000073A1 (en) *	1984-06-14	1986-01-03	BIOGAL Gyógyszergyár	Process for preparing adriamycine and halide salts thereof

Also Published As

Publication number	Publication date
DE1917874C3 (en)	1980-10-02
IL31966A (en)	1972-11-28
DE1917874B2 (en)	1980-02-07
DK126987B (en)	1973-09-10
DE1917874A1 (en)	1969-11-06
SE359293B (en)	1973-08-27
NO133271B (en)	1975-12-29
YU34389B (en)	1979-07-10
NO133271C (en)	1976-04-07
NL6904844A (en)	1969-10-14
YU85869A (en)	1978-12-31
FR2007443A1 (en)	1970-01-09
NL145536B (en)	1975-04-15
IL31966A0 (en)	1969-06-25
CH518250A (en)	1972-01-31
GB1217133A (en)	1970-12-31
BE731398A (en)	1969-10-13
ES365907A1 (en)	1971-03-16

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Legal Events

Date	Code	Title	Description
1988-06-15	ELA	Expired due to lapse of time