AT286964B - Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts - Google Patents

Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts

Info

Publication number
AT286964B
AT286964B AT915967A AT915967A AT286964B AT 286964 B AT286964 B AT 286964B AT 915967 A AT915967 A AT 915967A AT 915967 A AT915967 A AT 915967A AT 286964 B AT286964 B AT 286964B
Authority
AT
Austria
Prior art keywords
alkylaminoethanols
acyloxy
dihydroxy
phenyl
preparation
Prior art date
Application number
AT915967A
Other languages
German (de)
Inventor
Kjell Ingvar Leopold Wetterlin
Leif Aake Svensson
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Application granted granted Critical
Publication of AT286964B publication Critical patent/AT286964B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/48—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT915967A 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts AT286964B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE14182/66A SE335359B (en) 1966-10-19 1966-10-19

Publications (1)

Publication Number Publication Date
AT286964B true AT286964B (en) 1971-01-11

Family

ID=20298669

Family Applications (4)

Application Number Title Priority Date Filing Date
AT915967A AT286964B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT941969A AT288356B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT09421/69A AT287679B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT09420/69A AT287678B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXY-PHENYL) -2-ALKYLAMINO-AETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS

Family Applications After (3)

Application Number Title Priority Date Filing Date
AT941969A AT288356B (en) 1966-10-19 1967-10-10 Process for the preparation of new 1- (3 ', 5'-dihydroxy- or -acyloxy-phenyl) -2-alkylaminoethanols and their physiologically acceptable acid addition salts
AT09421/69A AT287679B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXYPHENYL) -2-CYCLOBUTYLAMINOETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS
AT09420/69A AT287678B (en) 1966-10-19 1967-10-10 PROCESS FOR THE PRODUCTION OF NEW 1- (3 ', 5'-DIHYDROXY-OR ACYLOXY-PHENYL) -2-ALKYLAMINO-AETHANOLS AND THEIR PHYSIOLOGICALLY COMPATIBLE ACID ADDITIONAL SALTS

Country Status (13)

Country Link
AT (4) AT286964B (en)
BE (1) BE704932A (en)
CH (1) CH510625A (en)
DE (2) DE1793759C3 (en)
DK (2) DK128491B (en)
ES (5) ES346131A1 (en)
FI (1) FI50786C (en)
FR (1) FR8011M (en)
GB (1) GB1199630A (en)
IT (1) IT8048168A0 (en)
NL (2) NL151693B (en)
NO (1) NO120686B (en)
SE (1) SE335359B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138581A (en) 1969-04-01 1979-02-06 Sterling Drugs Inc. 3(Hydroxy or hydroxymethyl)-4(hydroxy)-α-(aminomethyl)benzyl alcohols
CY1271A (en) * 1980-07-09 1985-03-08 Draco Ab Therapeutically active derivatives of phenylethanol amines
DE3163871D1 (en) 1980-07-09 1984-07-05 Draco Ab 1-(dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
US4853381A (en) * 1984-04-17 1989-08-01 Glaxo Group Limited Ethanolamine compounds
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
EP0213108A3 (en) * 1985-06-26 1987-07-15 Kurt Dr. Burghart Pharmaceutical preparation containing an antihypotonic as the active agent
WO2013081565A1 (en) 2011-11-21 2013-06-06 Mahmut Bilgic Pharmaceutical compositions comprising roflumilast and terbutaline
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
WO2018182546A1 (en) 2017-03-27 2018-10-04 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Stabilized pharmaceutical syrup composition comprising terbutaline sulphate and ambroxol hydrochloride
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
CN110057932B (en) * 2019-04-22 2022-03-15 上海旭东海普药业有限公司 Method for analyzing terbutaline sulfate related substances by high performance liquid chromatography
CN111440078A (en) * 2020-04-26 2020-07-24 梯尔希（南京）药物研发有限公司 Preparation method of terbutaline derivative
CN113264839B (en) * 2021-04-27 2022-08-30 苏州弘森药业股份有限公司 Method for preparing levo-terbutaline by using chiral prosthetic group
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
CN120583945A (en) 2023-01-20 2025-09-02 阿托基公司 Beta2-adrenergic receptor agonists for the treatment or prevention of muscle wasting
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses
GB202403169D0 (en) 2024-03-05 2024-04-17 Atrogi Ab New medical uses
WO2025238248A1 (en) 2024-05-17 2025-11-20 Atrogi Ab USE OF β2-ADRENERGIC RECEPTOR AGONISTS IN TREATING MUSCLE WASTING

Also Published As

Publication number Publication date
IT8048168A0 (en) 1980-03-14
GB1199630A (en) 1970-07-22
ES361429A1 (en) 1970-11-01
DE1643296C3 (en) 1974-06-12
AT287679B (en) 1971-02-10
DE1643296A1 (en) 1971-09-30
NO120686B (en) 1970-11-23
DK468876A (en) 1976-10-18
AT288356B (en) 1971-03-10
FR8011M (en) 1970-07-27
FI50786B (en) 1976-03-31
DE1793759B2 (en) 1978-05-11
ES361433A1 (en) 1970-11-01
NL7513854A (en) 1976-03-31
BE704932A (en) 1968-02-15
CH510625A (en) 1971-07-31
NL151693B (en) 1976-12-15
SE335359B (en) 1971-05-24
DE1643296B2 (en) 1973-10-25
DE1793759C3 (en) 1979-01-11
FI50786C (en) 1976-07-12
ES346131A1 (en) 1969-05-16
NL6714191A (en) 1968-04-22
DK128491B (en) 1974-05-13
DE1793759A1 (en) 1973-08-16
AT287678B (en) 1971-02-10
ES361431A1 (en) 1970-11-01
ES361432A1 (en) 1970-11-01

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time