AT323155B - PROCESS FOR THE PREPARATION OF NEW TETRAHYDROCARBAZOLE DERIVATIVES AND THEIR SALT - Google Patents
PROCESS FOR THE PREPARATION OF NEW TETRAHYDROCARBAZOLE DERIVATIVES AND THEIR SALTInfo
- Publication number
- AT323155B AT323155B AT449173A AT449173A AT323155B AT 323155 B AT323155 B AT 323155B AT 449173 A AT449173 A AT 449173A AT 449173 A AT449173 A AT 449173A AT 323155 B AT323155 B AT 323155B
- Authority
- AT
- Austria
- Prior art keywords
- salt
- preparation
- tetrahydrocarbazole derivatives
- new
- new tetrahydrocarbazole
- Prior art date
Links
- XKLNOVWDVMWTOB-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1h-carbazole Chemical class N1C2=CC=CC=C2C2=C1CCCC2 XKLNOVWDVMWTOB-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722226703 DE2226703A1 (en) | 1972-05-25 | 1972-05-25 | NEW TETRAHYDROCARBAZOLE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT323155B true AT323155B (en) | 1975-06-25 |
Family
ID=5846530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT449173A AT323155B (en) | 1972-05-25 | 1973-05-23 | PROCESS FOR THE PREPARATION OF NEW TETRAHYDROCARBAZOLE DERIVATIVES AND THEIR SALT |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4941367A (en) |
| AT (1) | AT323155B (en) |
| AU (1) | AU5607873A (en) |
| BE (1) | BE800066A (en) |
| CA (1) | CA1005062A (en) |
| CH (1) | CH582144A5 (en) |
| CS (1) | CS179416B2 (en) |
| DD (1) | DD106170A5 (en) |
| DE (1) | DE2226703A1 (en) |
| FR (1) | FR2185414B1 (en) |
| GB (1) | GB1436893A (en) |
| NL (1) | NL7307313A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033797A1 (en) * | 1979-08-06 | 1981-08-19 | American Home Products Corporation | 1-Hydroxyalkanamine tetrahydrocarbazoles, their preparation, pharmaceutical compositions containing same and their preparation, intermediates therefor and their preparation |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6545034B1 (en) | 1999-07-23 | 2003-04-08 | The Regents Of The University Of California | Use of etodolac for the treatment of chronic lymphocytic leukemia |
| US7361680B2 (en) | 1999-07-23 | 2008-04-22 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
| US7129262B2 (en) | 1999-07-23 | 2006-10-31 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
| US7151100B1 (en) | 1999-07-23 | 2006-12-19 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
| US7105560B1 (en) | 1999-07-23 | 2006-09-12 | The Regents Of The University Of California | Use of etodolac in the treatment of multiple myeloma |
| DE10164564B4 (en) * | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazole derivatives as ligands for G-protein coupled receptors (GPCR) |
| AU2003295336A1 (en) | 2002-09-19 | 2004-04-08 | Dennis A. Carson | Use of etodoclac to treat hyperplasia |
| EP1677794B1 (en) * | 2003-09-12 | 2014-12-03 | Elixir Pharmaceuticals, Inc. | Methods of treating disorder |
| US20060074124A1 (en) * | 2003-09-12 | 2006-04-06 | Andrew Napper | Methods of treating a disorder |
| TW200524940A (en) * | 2003-10-02 | 2005-08-01 | Salmedix Inc | Indole derivatives |
| US8580841B2 (en) * | 2008-07-23 | 2013-11-12 | Arena Pharmaceuticals, Inc. | Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders |
| HRP20160890T1 (en) | 2008-08-27 | 2016-09-23 | Arena Pharmaceuticals, Inc. | SUBSTITUTED TRICYCLIC ACID DERIVATIVES AS S1P1-RECEPTOR AGONISTS USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS |
| JP5856980B2 (en) | 2010-01-27 | 2016-02-10 | アリーナ ファーマシューティカルズ, インコーポレイテッド | (R) -2- (7- (4-Cyclopentyl-3- (trifluoromethyl) benzyloxy) -1,2,3,4-tetrahydrocyclopenta [b] indol-3-yl) acetic acid and its salts Process for preparation |
| CN105503882B (en) | 2010-03-03 | 2019-07-05 | 艾尼纳制药公司 | The method for preparing S1P1 receptor modulators and its crystal form |
| PL3242666T3 (en) | 2015-01-06 | 2025-02-17 | Arena Pharmaceuticals, Inc. | Compound for use in treating conditions related to the s1p1 receptor |
| BR112017027656B1 (en) | 2015-06-22 | 2023-12-05 | Arena Pharmaceuticals, Inc. | CRYSTALLINE HABIT OF SALT-FREE PLATE OF ACID L-ARGININE (R)-2-(7-(4- CYCLOPENTYL-3-(TRIFLUOROMETHYL)BENZYLOXY)- 1,2,3,4-TETRA-HYDROCYCLO-PENTA[B ]INDOL-3- IL)ACETIC, PHARMACEUTICAL COMPOSITION THAT COMPRISES IT, ITS USES AND METHOD OF PREPARATION THEREOF |
| MX2019009841A (en) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compounds and methods for treatment of primary biliary cholangitis. |
| MX2019009843A (en) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations. |
| CA3102136A1 (en) | 2018-06-06 | 2019-12-12 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the s1p1 receptor |
| CN112955431A (en) | 2018-09-06 | 2021-06-11 | 艾尼纳制药公司 | Compounds useful for the treatment of autoimmune and inflammatory disorders |
| CN114634442B (en) * | 2022-04-02 | 2023-10-13 | 内蒙古民族大学 | Preparation method of tetrahydrocarbazolone compound |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH586678A5 (en) * | 1970-05-25 | 1977-04-15 | Hoffmann La Roche | |
| ZA715217B (en) * | 1970-08-20 | 1972-04-26 | Org Nv | Anti-inflammatory preparations |
-
1972
- 1972-05-25 DE DE19722226703 patent/DE2226703A1/en active Pending
-
1973
- 1973-04-17 DD DD17023273A patent/DD106170A5/xx unknown
- 1973-05-14 GB GB2279573A patent/GB1436893A/en not_active Expired
- 1973-05-16 CS CS350973A patent/CS179416B2/en unknown
- 1973-05-17 CH CH707473A patent/CH582144A5/xx not_active IP Right Cessation
- 1973-05-23 AT AT449173A patent/AT323155B/en not_active IP Right Cessation
- 1973-05-24 AU AU56078/73A patent/AU5607873A/en not_active Expired
- 1973-05-25 BE BE131549A patent/BE800066A/en unknown
- 1973-05-25 JP JP5848173A patent/JPS4941367A/ja active Pending
- 1973-05-25 CA CA172,234A patent/CA1005062A/en not_active Expired
- 1973-05-25 FR FR7319087A patent/FR2185414B1/fr not_active Expired
- 1973-05-25 NL NL7307313A patent/NL7307313A/xx not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033797A1 (en) * | 1979-08-06 | 1981-08-19 | American Home Products Corporation | 1-Hydroxyalkanamine tetrahydrocarbazoles, their preparation, pharmaceutical compositions containing same and their preparation, intermediates therefor and their preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7307313A (en) | 1973-11-27 |
| AU5607873A (en) | 1974-11-28 |
| CH582144A5 (en) | 1976-11-30 |
| CA1005062A (en) | 1977-02-08 |
| DD106170A5 (en) | 1974-06-05 |
| FR2185414B1 (en) | 1976-08-13 |
| DE2226703A1 (en) | 1973-12-13 |
| BE800066A (en) | 1973-11-26 |
| FR2185414A1 (en) | 1974-01-04 |
| JPS4941367A (en) | 1974-04-18 |
| GB1436893A (en) | 1976-05-26 |
| CS179416B2 (en) | 1977-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |