AT400907B - SENSOR MEMBRANE OF AN OPTICAL SENSOR - Google Patents
SENSOR MEMBRANE OF AN OPTICAL SENSOR Download PDFInfo
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- AT400907B AT400907B AT0152292A AT152292A AT400907B AT 400907 B AT400907 B AT 400907B AT 0152292 A AT0152292 A AT 0152292A AT 152292 A AT152292 A AT 152292A AT 400907 B AT400907 B AT 400907B
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- indicator
- polymer matrix
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- 239000012528 membrane Substances 0.000 title claims abstract description 22
- 230000003287 optical effect Effects 0.000 title claims abstract description 12
- 229920000642 polymer Polymers 0.000 claims abstract description 21
- 239000000126 substance Substances 0.000 claims abstract description 21
- 239000011159 matrix material Substances 0.000 claims abstract description 13
- 229910052723 transition metal Inorganic materials 0.000 claims abstract description 9
- 150000003624 transition metals Chemical class 0.000 claims abstract description 9
- 239000003446 ligand Substances 0.000 claims abstract description 7
- 229910017053 inorganic salt Inorganic materials 0.000 claims abstract description 6
- 229910000071 diazene Inorganic materials 0.000 claims abstract description 4
- 150000008282 halocarbons Chemical class 0.000 claims abstract description 3
- 239000004793 Polystyrene Substances 0.000 claims abstract 7
- 229920002223 polystyrene Polymers 0.000 claims abstract 6
- 229920000909 polytetrahydrofuran Polymers 0.000 claims abstract 6
- 229920002678 cellulose Polymers 0.000 claims abstract 3
- 239000001913 cellulose Substances 0.000 claims abstract 3
- 239000000975 dye Substances 0.000 claims description 12
- ROFVEXUMMXZLPA-UHFFFAOYSA-N Bipyridyl Chemical compound N1=CC=CC=C1C1=CC=CC=N1 ROFVEXUMMXZLPA-UHFFFAOYSA-N 0.000 claims description 8
- YNPNZTXNASCQKK-UHFFFAOYSA-N Phenanthrene Natural products C1=CC=C2C3=CC=CC=C3C=CC2=C1 YNPNZTXNASCQKK-UHFFFAOYSA-N 0.000 claims description 6
- DGEZNRSVGBDHLK-UHFFFAOYSA-N [1,10]phenanthroline Chemical compound C1=CN=C2C3=NC=CC=C3C=CC2=C1 DGEZNRSVGBDHLK-UHFFFAOYSA-N 0.000 claims description 6
- 239000004014 plasticizer Substances 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 229910052760 oxygen Inorganic materials 0.000 claims description 4
- 239000001301 oxygen Substances 0.000 claims description 4
- 229910052707 ruthenium Inorganic materials 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 229910052762 osmium Inorganic materials 0.000 claims description 3
- 229910052697 platinum Inorganic materials 0.000 claims description 3
- 230000035945 sensitivity Effects 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims 6
- 229920002284 Cellulose triacetate Polymers 0.000 claims 4
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 4
- 239000001856 Ethyl cellulose Substances 0.000 claims 4
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 4
- NNLVGZFZQQXQNW-ADJNRHBOSA-N [(2r,3r,4s,5r,6s)-4,5-diacetyloxy-3-[(2s,3r,4s,5r,6r)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6s)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl acetate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@H]1[C@@H]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)OC(C)=O)COC(=O)C)[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O NNLVGZFZQQXQNW-ADJNRHBOSA-N 0.000 claims 4
- 229920001249 ethyl cellulose Polymers 0.000 claims 4
- 235000019325 ethyl cellulose Nutrition 0.000 claims 4
- 229920002799 BoPET Polymers 0.000 claims 3
- 239000005041 Mylar™ Substances 0.000 claims 3
- 238000003756 stirring Methods 0.000 claims 3
- 229910052741 iridium Inorganic materials 0.000 claims 2
- 229910052763 palladium Inorganic materials 0.000 claims 2
- 229910052702 rhenium Inorganic materials 0.000 claims 2
- 229910052703 rhodium Inorganic materials 0.000 claims 2
- 238000004528 spin coating Methods 0.000 claims 2
- 238000010345 tape casting Methods 0.000 claims 2
- 150000004291 polyenes Chemical class 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- 239000000463 material Substances 0.000 description 6
- 229920001296 polysiloxane Polymers 0.000 description 6
- 239000012876 carrier material Substances 0.000 description 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- MGWAVDBGNNKXQV-UHFFFAOYSA-N diisobutyl phthalate Chemical compound CC(C)COC(=O)C1=CC=CC=C1C(=O)OCC(C)C MGWAVDBGNNKXQV-UHFFFAOYSA-N 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-M perchlorate Inorganic materials [O-]Cl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-M 0.000 description 2
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical compound OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 description 2
- 229920000260 silastic Polymers 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
- 229920005372 Plexiglas® Polymers 0.000 description 1
- 239000012327 Ruthenium complex Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001278 adipic acid derivatives Chemical class 0.000 description 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 238000005253 cladding Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 150000002503 iridium Chemical class 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Natural products C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- SYQBFIAQOQZEGI-UHFFFAOYSA-N osmium atom Chemical compound [Os] SYQBFIAQOQZEGI-UHFFFAOYSA-N 0.000 description 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 1
- -1 platinum metals Chemical class 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920002037 poly(vinyl butyral) polymer Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 125000003367 polycyclic group Chemical group 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 150000004032 porphyrins Chemical class 0.000 description 1
- 150000003303 ruthenium Chemical class 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
- G01N31/223—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating presence of specific gases or aerosols
- G01N31/225—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating presence of specific gases or aerosols for oxygen, e.g. including dissolved oxygen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
- G01N31/223—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating presence of specific gases or aerosols
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/20—Oxygen containing
- Y10T436/207497—Molecular oxygen
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Fluid Pressure (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
Description
AT 400 907 BAT 400 907 B
Die Erfindung betrifft eine Sensormembran eines optischen Sensors zur Bestimmung von O2, H202, SO2 oder halogenierter Kohlenwasserstoffe in einer Probe, mit einer homogen in der Polymermatrix der Sensormembran immobilisierten Indikatorsubstanz, welche mit der Probe in zumindest indirektem Kontakt steht und bei einer Änderung des zu messenden Parameters zumindest eine ihrer optischen Eigenschaften ändert, wobei die Indikatorsubstanz ein anorganisches Salz eines Übergangsmetallkomplexes mit a-Diiminliganden enthält.The invention relates to a sensor membrane of an optical sensor for the determination of O2, H202, SO2 or halogenated hydrocarbons in a sample, with an indicator substance immobilized homogeneously in the polymer matrix of the sensor membrane, which is in at least indirect contact with the sample and when there is a change in the measurement Parameters changes at least one of their optical properties, the indicator substance containing an inorganic salt of a transition metal complex with a-diimine ligands.
Es sind bereits eine Vielzahl von Indikatorsubstanzen und Sensormembranen bekannt, welche auf die eingangs erwähnten Substrate mit einer Änderung einer optischen Eigenschaft der Indikatorsubstanz reagieren. Die Änderung dieser Eigenschaft, beispielsweise Fluoreszenzintensität, Fluoreszenzabklingzeit, Absorption u.s.w., kann mit bekannten optischen Verfahren und Meßeinrichtungen erfaßt und der zu messenden Größe der Substratkonzentration zugeordnet werden.A large number of indicator substances and sensor membranes are already known, which react to the substrates mentioned at the outset by changing an optical property of the indicator substance. The change in this property, for example fluorescence intensity, fluorescence decay time, absorption, etc., can be detected using known optical methods and measuring devices and assigned to the size of the substrate concentration to be measured.
Beispielsweise ist es aus "A New Material for Optical Oxygen Measurement, with the Indicator Embedded in an Aqueous Phase" (Mikrochimica Acta 1986 III, 359-366) bekannt, Indikatorfarbstoffe an Trägermaterialen zu adsorbieren und diese beladenen Trägermaterialien in Polymere einzubetten. Als Indikatorfarbstoff wird ein Rutheniumkomplex nämlich Rutheniumtris(dipyridyl)-dichlorid (Ru(bpy)3Cl2 verwendet. Als Trägermaterial findet Kieselgel Verwendung, welches in Silicon, z.B. RTV-118 (Wacker-Chemie, Burghausen, DE) eingebettet wird. Die entstehenden Sensormembranen zeichnen sich durch hohe Sauerstoffempfindlichkeit aus, haben jedoch nur eine durchschnittliche bis geringe Signalintensität und eine in wäßriger Phase instabile Sensorkennlinie. Nachteiligerweise zeigt sich auch eine ausgeprägte Nichtlinearität der technisch aufwendig herzustellenden Sensormembran.For example, it is from " A New Material for Optical Oxygen Measurement, with the Indicator Embedded in an Aqueous Phase " (Mikrochimica Acta 1986 III, 359-366) known to adsorb indicator dyes on carrier materials and to embed these loaded carrier materials in polymers. A ruthenium complex, namely ruthenium tris (dipyridyl) dichloride (Ru (bpy) 3Cl2, is used as the indicator dye. Silica gel, which is embedded in silicone, for example RTV-118 (Wacker-Chemie, Burghausen, DE), is used as the carrier material. The resulting sensor membranes are drawn are characterized by high sensitivity to oxygen, but only have an average to low signal intensity and an unstable sensor characteristic curve in the aqueous phase, and disadvantageously there is also a pronounced non-linearity of the sensor membrane, which is technically complex to manufacture.
Weiters ist in diesem Zusammenhang aus der US-PS 5 030 420 bekannt geworden, Farbstoffe, wie beispielsweise Komplexe der Platinmetalle mit β-Diimin-und Porphyrinliganden in Polieren wie z.B. PVC, Plexiglas, Silicon- und Naturgummi, Polykarbonat, Teflon u.s.w. zu verwenden. Als Liganden werden unter anderem 2,2'-bipyridin (bpy), 1,10-phenantrolin (phen) und 4,7-diphenyl-1,20-phenantrolin (diph) genannt. Der Farbstoff kann durch Diffusion in das Polymer eingebracht oder mit dem Prepolymer vermischt werden. Schließlich kann auch eine ionische oder kovalente Bindung an das Polymer erfolgen. Dadurch können jedoch wesentliche Farbstoffeigenschaften negativ beeinflußt werden. So ist insbesondere die in dieser US-PS speziell hervorgehobene Immobilisierung von Ru(diph)-perchlorat in Silicon GE RTV SILASTIC 118 (General Electric USA) kein Beweis für eine Lösung des Farbstoffes direkt in der Siliconmatrix, da das hier verwendete Silicon Füllstoffe aufweist und der Farbstoff daran adsorbiert ist und nicht in der Matrix gelöst vorliegt.Furthermore, in this connection it is known from US Pat. No. 5,030,420 to use dyes, such as, for example, complexes of platinum metals with β-diimine and porphyrin ligands in polishing, such as e.g. PVC, plexiglass, silicone and natural rubber, polycarbonate, Teflon, etc. to use. 2,2'-bipyridine (bpy), 1,10-phenantroline (phen) and 4,7-diphenyl-1,20-phenantroline (diph) are mentioned as ligands. The dye can be diffused into the polymer or mixed with the prepolymer. Finally, an ionic or covalent bond to the polymer can also take place. However, this can have a negative impact on essential dye properties. In particular, the immobilization of Ru (diph) perchlorate in silicone GE RTV SILASTIC 118 (General Electric USA), which is especially emphasized in this US patent, is no proof of a solution of the dye directly in the silicone matrix, since the silicone used here contains fillers and the dye is adsorbed on it and is not dissolved in the matrix.
Weiters ist aus der EP-A 0 190 830 die homogene Immobilisierung von Übergangsmetallkomplexen in Polymeren mit hoher Sauerstoffpermeabilität bekannt geworden, welche zu den eingangs beschriebenen Sensormembranen führt. Im zuletzt genannten Beispiel erfolgt eine homogene Immobilisierung von beispielsweise Rutheniumkomplexen in PVC mit geringen Weichmacherkonzentrationen. Dieses Material wird dann anstelle des Mantels eines optischen Lichtleiters angebracht und über den Lichtleiter optisch angeregt. Als Farbstoffe werden Ruthenium-, Osmium- und Iridiumkomplexe genannt, wobei die Komplexe mit einem Gegenion elektrisch abgesättigt sind. Als Polymere finden PVC, Polyvinylbutyral sowie Polyvinylacetat Verwendung. Als Weichmacher werden Phthalsäure-, Benzoesäure-, Sebacinsäure- und Adipinsäurederivate sowie, Paraffine verwendet. Als Lösungsmittel werden beispielsweise Aceton und Ethanol genannt. Eine typische Sensormembran aus der EP 0 190 830 besteht somit aus PVC, Ru(diph)3-perchlorat als Farbstoff, Diisobutylphthalat als Weichmacher und Methylenchlorid als Lösungsmittel.Furthermore, EP-A 0 190 830 has disclosed the homogeneous immobilization of transition metal complexes in polymers with high oxygen permeability, which leads to the sensor membranes described at the outset. In the last-mentioned example, a homogeneous immobilization of, for example, ruthenium complexes in PVC with low plasticizer concentrations takes place. This material is then applied instead of the cladding of an optical light guide and optically excited via the light guide. Ruthenium, osmium and iridium complexes are mentioned as dyes, the complexes being electrically saturated with a counter ion. PVC, polyvinyl butyral and polyvinyl acetate are used as polymers. Phthalic acid, benzoic acid, sebacic acid and adipic acid derivatives and paraffins are used as plasticizers. Acetone and ethanol are mentioned as solvents. A typical sensor membrane from EP 0 190 830 thus consists of PVC, Ru (diph) 3-perchlorate as a dye, diisobutyl phthalate as a plasticizer and methylene chloride as a solvent.
Die bisher beschriebenen Sensormembranen weisen somit anorganische Salze von Übergangsmetallkomplexen auf, die an Trägermaterialien gebunden werden, welche entweder im Polymer als Füllstoff enthalten sind oder dem Polymer extra zugesetzt werden bzw. in den Weichmacheranteilen von Kunststoffen gelöst werden. Bei den Polymeren handelt es sich in den beschriebenen Fällen im wesentlichen um Silicone, welche bei Zimmertemperatur kondensationsvernetzend sind (Silicon RTV-118 von Wacker-Chemie, Burghausen DE oder GE RTV SILASTIC 118 von General Electric USA), bzw. um ein typisches PVC-Material.The sensor membranes described so far thus have inorganic salts of transition metal complexes which are bound to support materials which are either contained in the polymer as a filler or are added to the polymer separately or are dissolved in the plasticizer portions of plastics. In the cases described, the polymers are essentially silicones which are condensation-crosslinking at room temperature (silicone RTV-118 from Wacker-Chemie, Burghausen DE or GE RTV SILASTIC 118 from General Electric USA), or a typical PVC Material.
In der AT-PS 379 688 wird ein Sensor beschrieben, bei welchem der Indikator ein polyzyklischer homo-oder heterozyklischer aromatischer Kohlenwasserstoff ist. Als Trägermaterial sind weichmacherkompatible Polymere vorgesehen, welche neben den eingebetteten Indikatormolekülen noch zusätzlich Weichmacher enthalten.AT-PS 379 688 describes a sensor in which the indicator is a polycyclic homocyclic or heterocyclic aromatic hydrocarbon. Plasticizer-compatible polymers are provided as the carrier material, which in addition to the embedded indicator molecules also contain plasticizers.
Aus der AT-PS 387 466 ist es bekannt, einen plättchenförmigen Träger mit einem immobilisierten fluoreszenzoptischen Indikatormaterial zu versehen, wobei die Aufnahmefläche für das immobilisierte Indikatormaterial mit gleichmäßigen, dicht verteilten Erhebungen versehen ist. Der Indikator ist hier somit auf einer durch Erhebungen vergrößerten Fläche immobilisiert und nicht in einer Membran homogen verteilt. 2From AT-PS 387 466 it is known to provide a platelet-shaped carrier with an immobilized fluorescent optical indicator material, the receiving surface for the immobilized indicator material being provided with uniform, densely distributed elevations. The indicator is thus immobilized on an area enlarged by surveys and not homogeneously distributed in a membrane. 2nd
Claims (5)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0152292A AT400907B (en) | 1992-07-24 | 1992-07-24 | SENSOR MEMBRANE OF AN OPTICAL SENSOR |
| JP5175511A JPH07111401B2 (en) | 1992-07-24 | 1993-07-15 | Sensor membrane of optical sensor |
| AT93890142T ATE157770T1 (en) | 1992-07-24 | 1993-07-21 | SENSOR MEMBRANE OF AN OPTICAL SENSOR |
| DE59307245T DE59307245D1 (en) | 1992-07-24 | 1993-07-21 | Sensor membrane of an optical sensor |
| EP93890142A EP0585212B1 (en) | 1992-07-24 | 1993-07-21 | Sensor membrane of an optical sensor |
| US08/843,296 US6139798A (en) | 1992-07-24 | 1997-04-14 | Sensor membrane of an optical sensor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0152292A AT400907B (en) | 1992-07-24 | 1992-07-24 | SENSOR MEMBRANE OF AN OPTICAL SENSOR |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA152292A ATA152292A (en) | 1995-08-15 |
| AT400907B true AT400907B (en) | 1996-04-25 |
Family
ID=3515428
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0152292A AT400907B (en) | 1992-07-24 | 1992-07-24 | SENSOR MEMBRANE OF AN OPTICAL SENSOR |
| AT93890142T ATE157770T1 (en) | 1992-07-24 | 1993-07-21 | SENSOR MEMBRANE OF AN OPTICAL SENSOR |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93890142T ATE157770T1 (en) | 1992-07-24 | 1993-07-21 | SENSOR MEMBRANE OF AN OPTICAL SENSOR |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6139798A (en) |
| EP (1) | EP0585212B1 (en) |
| JP (1) | JPH07111401B2 (en) |
| AT (2) | AT400907B (en) |
| DE (1) | DE59307245D1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10025097A1 (en) * | 2000-05-20 | 2001-11-29 | Bosch Gmbh Robert | Optical sensor for detecting carbon monoxide comprises radiation source, and sensitive layer containing transition metal compound which forms complex with gas to be determined |
| DE10127059B4 (en) * | 2000-06-24 | 2005-03-24 | Robert Bosch Gmbh | Optical sensor with particle-sensitive layer |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5833882A (en) * | 1996-08-23 | 1998-11-10 | Japan Pionics Co., Ltd. | Detecting agent |
| DE69734401T2 (en) * | 1997-02-27 | 2006-07-27 | Terumo Cardiovascular Systems Corp. | CASSETTE FOR MEASURING BLOOD PARAMETERS |
| US5822137A (en) * | 1997-02-27 | 1998-10-13 | Minnesota Mining & Manufacturing Co. | Assembly for retaining optical components |
| US6009339A (en) | 1997-02-27 | 1999-12-28 | Terumo Cardiovascular Systems Corporation | Blood parameter measurement device |
| US5997818A (en) * | 1997-02-27 | 1999-12-07 | Minnesota Mining And Manufacturing Company | Cassette for tonometric calibration |
| DE19831770C2 (en) * | 1998-07-15 | 2001-12-13 | Inst Chemo Biosensorik | Process for the production of a sensor membrane |
| DE10051220A1 (en) * | 2000-10-16 | 2002-04-25 | Mettler Toledo Gmbh | Optical sensor for determining an analyte and method for its production |
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- 1993-07-21 DE DE59307245T patent/DE59307245D1/en not_active Expired - Lifetime
- 1993-07-21 AT AT93890142T patent/ATE157770T1/en active
- 1993-07-21 EP EP93890142A patent/EP0585212B1/en not_active Expired - Lifetime
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| AT379688B (en) * | 1982-11-22 | 1986-02-10 | List Hans | SENSOR ELEMENT FOR DETERMINING THE O2 CONTENT OF A SAMPLE |
| AT387466B (en) * | 1983-11-17 | 1989-01-25 | List Hans | SENSOR ELEMENT FOR FLUORESCENT OPTICAL MEASUREMENT |
| AT384891B (en) * | 1983-12-09 | 1988-01-25 | Avl Verbrennungskraft Messtech | MEASURING DEVICE FOR DETERMINING THE CONCENTRATION OF HALOGENIDES AND PSEUDOHALOGENIDES, AND METHOD FOR PRODUCING A SENSOR ELEMENT FOR SUCH A DEVICE |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10025097A1 (en) * | 2000-05-20 | 2001-11-29 | Bosch Gmbh Robert | Optical sensor for detecting carbon monoxide comprises radiation source, and sensitive layer containing transition metal compound which forms complex with gas to be determined |
| DE10025097B4 (en) * | 2000-05-20 | 2004-04-15 | Robert Bosch Gmbh | Optical sensor and method for manufacturing the same |
| DE10127059B4 (en) * | 2000-06-24 | 2005-03-24 | Robert Bosch Gmbh | Optical sensor with particle-sensitive layer |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07111401B2 (en) | 1995-11-29 |
| DE59307245D1 (en) | 1997-10-09 |
| US6139798A (en) | 2000-10-31 |
| JPH06213816A (en) | 1994-08-05 |
| EP0585212A3 (en) | 1994-11-30 |
| EP0585212B1 (en) | 1997-09-03 |
| ATE157770T1 (en) | 1997-09-15 |
| EP0585212A2 (en) | 1994-03-02 |
| ATA152292A (en) | 1995-08-15 |
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