AT511130A5 - Polypeptidmaterial mit flexiblen Poreneigenschaften - Google Patents

Polypeptidmaterial mit flexiblen Poreneigenschaften Download PDF

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Publication number
AT511130A5
AT511130A5 ATA9496/2009A AT94962009A AT511130A5 AT 511130 A5 AT511130 A5 AT 511130A5 AT 94962009 A AT94962009 A AT 94962009A AT 511130 A5 AT511130 A5 AT 511130A5
Authority
AT
Austria
Prior art keywords
polypeptide material
pore properties
flexible pore
flexible
properties
Prior art date
Application number
ATA9496/2009A
Other languages
English (en)
Other versions
AT511130A2 (de
Original Assignee
Kemijski Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kemijski Inst filed Critical Kemijski Inst
Publication of AT511130A2 publication Critical patent/AT511130A2/de
Publication of AT511130A5 publication Critical patent/AT511130A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Toxicology (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Die Erfindung ist das Polypeptidmaterial mit flexiblen Poreneigenschaften, das durch das zwei- oder dreidimensionale Zusammenfügen von Fusionsproteinen aus mindestens zwei Proteindomänen entsteht, wobei mindestens eine Domäne ein Doppelwendel und mindestens eine die Protein-Oligomerisationsdomäne darstellt. Die Erfindung bezieht sich auf das Polypeptidmaterial, das z.B. bei der chemischen Katalyse und bei der Trennung der Moleküle auf Grundlage ihrer Eigenschaften verwendet wird.
ATA9496/2009A 2009-10-12 2009-10-12 Polypeptidmaterial mit flexiblen Poreneigenschaften AT511130A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SI2009/000048 WO2011046520A1 (en) 2009-10-12 2009-10-12 Polypeptide material with adjustable pore properties

Publications (2)

Publication Number Publication Date
AT511130A2 AT511130A2 (de) 2012-09-15
AT511130A5 true AT511130A5 (de) 2015-07-15

Family

ID=42174007

Family Applications (1)

Application Number Title Priority Date Filing Date
ATA9496/2009A AT511130A5 (de) 2009-10-12 2009-10-12 Polypeptidmaterial mit flexiblen Poreneigenschaften

Country Status (2)

Country Link
AT (1) AT511130A5 (de)
WO (1) WO2011046520A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014126828A1 (en) * 2013-02-15 2014-08-21 Merck Sharp & Dohme Corp. Novel ph-switchable peptides for membrane insertion and pore formation
JP2020519244A (ja) * 2017-04-20 2020-07-02 アンスティトゥート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシャルシュ・メディカル・（インセルム） 研究及び生物医学応用のためのペプチド、特にポリペプチド、ファージディスプレイスクリーニング法及び関連する手段、並びにその使用
CA3183086A1 (en) * 2020-05-11 2021-11-18 Janssen Pharmaceuticals, Inc. Stabilized coronavirus spike protein fusion proteins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2393959A (en) * 2002-10-08 2004-04-14 Isis Innovation Protein lattice

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030219451A1 (en) * 2001-10-29 2003-11-27 Whitehead Institute For Biomedical Research Stable helical C peptides and uses therefor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2393959A (en) * 2002-10-08 2004-04-14 Isis Innovation Protein lattice

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Cantor CR: "Genetically engineered microorganisms containing streptavidin for environmental monitoring" 15 December 1999 (1999-12-15), XP002585493 Retrieved from the Internet: URL:http://www.dtic.mil/cgi-bin/GetTRDoc?AD=ADA371484&Location=U2&doc=GetTRDoc.pdf> [retrieved on 2010-05-31] *
Contegno F, Cioce M, Pelicci PG, Minucci S. Targeting protein inactivation through an oligomerization chain reaction. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1865-9. Epub 2002 Feb 12. *
D1: Harborth J, Wang J, Gueth-Hallonet C, Weber K, Osborn M. Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice. EMBO J. 1999 Mar 15;18(6):1689-700. *

Also Published As

Publication number Publication date
AT511130A2 (de) 2012-09-15
WO2011046520A1 (en) 2011-04-21

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AT511130A5 (de) Polypeptidmaterial mit flexiblen Poreneigenschaften

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REJ Rejection

Effective date: 20160515