AT73653B - Process for the preparation of durable preparations of diaminodioxyarsenobenzene. - Google Patents
Process for the preparation of durable preparations of diaminodioxyarsenobenzene.Info
- Publication number
- AT73653B AT73653B AT73653DA AT73653B AT 73653 B AT73653 B AT 73653B AT 73653D A AT73653D A AT 73653DA AT 73653 B AT73653 B AT 73653B
- Authority
- AT
- Austria
- Prior art keywords
- preparations
- diaminodioxyarsenobenzene
- preparation
- durable
- ether
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title claims description 10
- 238000000034 method Methods 0.000 title claims description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 150000001298 alcohols Chemical class 0.000 claims description 4
- 239000011872 intimate mixture Substances 0.000 claims description 2
- 229910052783 alkali metal Inorganic materials 0.000 claims 2
- -1 alkali metal salts Chemical class 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000002244 precipitate Substances 0.000 claims 1
- 150000001447 alkali salts Chemical class 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- 229930195725 Mannitol Natural products 0.000 description 2
- 235000010355 mannitol Nutrition 0.000 description 2
- 239000000594 mannitol Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 244000248349 Citrus limon Species 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 239000004386 Erythritol Substances 0.000 description 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 1
- 235000019414 erythritol Nutrition 0.000 description 1
- 229940009714 erythritol Drugs 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Description
<Desc/Clms Page number 1>
Verfahren zur Darstellung haltbarer Präparate von Diaminodioxyar8enobenzol.
Es wurde gefunden, dass man feste, haltbare Präparate von Alkalisalzen des 4. 4'.
-Dioxy-3. 3'-diaminoarsenbenzols gewinnt, indem man diese Alkalisalze, in Wasser gelöst, mit polyvalenten Alkoholen, d. h. Alkoholen, die mehr als drei Hydroxyle enthalten, wie z. B. Erythrit und Mannit, versetzt und sodann aus dieser Lösung durch Zugabe von Alkohol und Äther die neuen Präparate fällt und abtrennt. Aller Wahrscheinlichkeit nach liegen in denselben nicht neue, chemische Verbindungen, sondern innige Gemenge der genannten Alkalisalze mit den mehrwertigen Alkoholen vor. Die neuen Präparate sind zitronengelbe, in Wasser leicht und mit alkalischer Reaktion lösliche, in Alkohol und Äther schwer lösliche Pulver. Ihre Lösung scheidet auf Zusatz von verdünnter Salzsäure zunächst Diaminodioxyarsenobenzol ab, welches durch mehr Salzsäure wieder gelöst wird.
Im Gegensatz zu den reinen Alkalisalzen des Diaminodioxyarsenobenzols halten, sich die neuen Präparate unverändert, wenn sie in Glasampullen unter Luftabschluss aufbewahrt werden.
Zur Darstellung der neuen Präparate verfährt man wie folgt :
EMI1.1
27'2'1 Mannit, gelöst in 100 < "M Wasser, hinzugegeben. Die entstehende Lösung wird mit 4 1 absolutem Alkohol und 4 1 Äther versetzt. Es scheidet sich ein gelbes Pulver ab, das abfiltriert, mit Alkohol und Äther gewaschen und im Vakuum getrocknet wird. Es hat die oben angegebenen Eigenschaften.
**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.
<Desc / Clms Page number 1>
Process for the preparation of durable preparations of diaminodioxyar8enobenzene.
It has been found that solid, durable preparations of alkali salts of the 4th 4 '.
-Dioxy-3. 3'-diaminoarsenobenzene is obtained by combining these alkali salts, dissolved in water, with polyvalent alcohols, d. H. Alcohols containing more than three hydroxyls, such as. B. erythritol and mannitol are added and then the new preparations fall and separate from this solution by adding alcohol and ether. In all probability they do not contain new chemical compounds, but intimate mixtures of the alkali salts mentioned with the polyhydric alcohols. The new preparations are lemon yellow powders that are easily soluble in water and with an alkaline reaction, and poorly soluble in alcohol and ether. Upon the addition of dilute hydrochloric acid, your solution initially separates diaminodioxyarsenobenzene, which is redissolved with more hydrochloric acid.
In contrast to the pure alkali salts of diaminodioxyarsenobenzene, the new preparations remain unchanged if they are stored in glass ampoules in the absence of air.
To display the new preparations, proceed as follows:
EMI1.1
27'2'1 mannitol, dissolved in 100 <"M water, is added. The resulting solution is mixed with 4 liters of absolute alcohol and 4 liters of ether. A yellow powder separates out, which is filtered off, washed with alcohol and ether and im Vacuum dried and has the properties given above.
** WARNING ** End of DESC field may overlap beginning of CLMS **.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT73653T | 1914-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT73653B true AT73653B (en) | 1917-08-10 |
Family
ID=3595315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT73653D AT73653B (en) | 1914-12-19 | 1914-12-19 | Process for the preparation of durable preparations of diaminodioxyarsenobenzene. |
Country Status (1)
| Country | Link |
|---|---|
| AT (1) | AT73653B (en) |
-
1914
- 1914-12-19 AT AT73653D patent/AT73653B/en active
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