ATA163691A - Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten - Google Patents

Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten

Info

Publication number
ATA163691A
ATA163691A AT0163691A AT163691A ATA163691A AT A163691 A ATA163691 A AT A163691A AT 0163691 A AT0163691 A AT 0163691A AT 163691 A AT163691 A AT 163691A AT A163691 A ATA163691 A AT A163691A
Authority
AT
Austria
Prior art keywords
new
production
acid derivatives
intermediate products
aminocephalosporanic acid
Prior art date
Application number
AT0163691A
Other languages
English (en)
Other versions
AT396108B (de
Inventor
Johannes Ludescher
Hubert Sturm
Josef Wieser
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT0163691A priority Critical patent/AT396108B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Priority to PT92113715T priority patent/PT528343E/pt
Priority to SG1996009489A priority patent/SG52784A1/en
Priority to AT92113715T priority patent/ATE224393T1/de
Priority to ES92113715T priority patent/ES2183804T3/es
Priority to EP92113715A priority patent/EP0528343B1/de
Priority to DE69232776T priority patent/DE69232776T2/de
Priority to KR1019920014890A priority patent/KR930004312A/ko
Priority to JP4221330A priority patent/JP2561780B2/ja
Publication of ATA163691A publication Critical patent/ATA163691A/de
Application granted granted Critical
Publication of AT396108B publication Critical patent/AT396108B/de
Priority to US08/437,084 priority patent/US5644052A/en
Priority to US08/437,083 priority patent/US5686604A/en
Priority to US08/947,215 priority patent/US6169180B1/en
Priority to KR1019990053237A priority patent/KR100286422B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT0163691A 1991-08-21 1991-08-21 Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten AT396108B (de)

Priority Applications (13)

Application Number Priority Date Filing Date Title
AT0163691A AT396108B (de) 1991-08-21 1991-08-21 Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
SG1996009489A SG52784A1 (en) 1991-08-21 1992-08-12 New process for the production of cephalosporines and novel intermediates in this process
AT92113715T ATE224393T1 (de) 1991-08-21 1992-08-12 Verfahren zur herstellung von cephalosporinen und zwischenverbindungen in diesem verfahren
ES92113715T ES2183804T3 (es) 1991-08-21 1992-08-12 Nuevo proceso para la produccion de cefalosporinas y nuevos intermedios en este proceso.
EP92113715A EP0528343B1 (de) 1991-08-21 1992-08-12 Verfahren zur Herstellung von Cephalosporinen und Zwischenverbindungen in diesem Verfahren
DE69232776T DE69232776T2 (de) 1991-08-21 1992-08-12 Verfahren zur Herstellung von Cephalosporinen und Zwischenverbindungen in diesem Verfahren
PT92113715T PT528343E (pt) 1991-08-21 1992-08-12 Novo processo para a producao de cefalosporinas e novos intermediarios neste processo
KR1019920014890A KR930004312A (ko) 1991-08-21 1992-08-19 세팔로스포린의 제조방법 및 이 방법에서의 중간체
JP4221330A JP2561780B2 (ja) 1991-08-21 1992-08-20 セファロスポリン類の新規製造法および新規中間体
US08/437,084 US5644052A (en) 1991-08-21 1995-05-05 Process for the production of cephalosporines and novel intermediates in this process
US08/437,083 US5686604A (en) 1991-08-21 1995-05-05 Cephalosporines
US08/947,215 US6169180B1 (en) 1991-08-21 1997-10-08 Process for the production of cephalosporines
KR1019990053237A KR100286422B1 (ko) 1991-08-21 1999-11-27 세팔로스포린의 제조방법 및 이 방법에서의 중간체

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0163691A AT396108B (de) 1991-08-21 1991-08-21 Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten

Publications (2)

Publication Number Publication Date
ATA163691A true ATA163691A (de) 1992-10-15
AT396108B AT396108B (de) 1993-06-25

Family

ID=3517697

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0163691A AT396108B (de) 1991-08-21 1991-08-21 Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
AT92113715T ATE224393T1 (de) 1991-08-21 1992-08-12 Verfahren zur herstellung von cephalosporinen und zwischenverbindungen in diesem verfahren

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT92113715T ATE224393T1 (de) 1991-08-21 1992-08-12 Verfahren zur herstellung von cephalosporinen und zwischenverbindungen in diesem verfahren

Country Status (9)

Country Link
US (3) US5686604A (de)
EP (1) EP0528343B1 (de)
JP (1) JP2561780B2 (de)
KR (2) KR930004312A (de)
AT (2) AT396108B (de)
DE (1) DE69232776T2 (de)
ES (1) ES2183804T3 (de)
PT (1) PT528343E (de)
SG (1) SG52784A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0164458B1 (ko) * 1995-04-04 1999-01-15 김은영 암모니오세팔로스포린 계열 항생제 및 그의 제조방법
AT403161B (de) * 1995-07-19 1997-11-25 Biochemie Gmbh Verfahren zur herstellung von cephemverbindungen
US5872249A (en) * 1995-09-01 1999-02-16 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same
US6011136A (en) * 1995-11-21 2000-01-04 Novartis Ag Cyclopeptolides
JP4033630B2 (ja) * 1998-06-22 2008-01-16 バジリア ファルマスーチカ アーゲー プロペニルセファロスポリン誘導体

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4049806A (en) * 1975-08-15 1977-09-20 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4112087A (en) * 1976-11-04 1978-09-05 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials having a substituted propenyl group in the 3-position
DE2659288A1 (de) * 1976-12-29 1978-07-06 Schering Ag Mittel mit bakterizider und fungizider wirkung
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
US4640798A (en) * 1982-05-26 1987-02-03 Lilly Industries Ltd. Intermediates for the preparation of penicillin and cephalosporin compounds
ZA84584B (en) * 1983-01-28 1984-09-26 Bristol Myers Co Substituted vinyl cephalosporins
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
AT382873B (de) * 1984-11-23 1987-04-27 Biochemie Gmbh Verfahren zur herstellung von cephalosporinderivaten
ATE121746T1 (de) * 1984-11-23 1995-05-15 Biochemie Gmbh Verfahren zur herstellung bissilylierter 3- iodmethylcephalosporinderivaten.
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
WO1987003875A1 (fr) * 1985-12-26 1987-07-02 Eisai Co., Ltd. Derives de cephalosporine
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
DE68929368T2 (de) * 1988-03-16 2002-08-14 Eisai Co., Ltd. Cephemderivate und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
JP2561780B2 (ja) 1996-12-11
JPH05194533A (ja) 1993-08-03
PT528343E (pt) 2002-12-31
US6169180B1 (en) 2001-01-02
EP0528343A3 (en) 1993-03-10
EP0528343A2 (de) 1993-02-24
US5644052A (en) 1997-07-01
KR100286422B1 (ko) 2001-03-15
SG52784A1 (en) 1998-09-28
KR930004312A (ko) 1993-03-22
US5686604A (en) 1997-11-11
EP0528343B1 (de) 2002-09-18
AT396108B (de) 1993-06-25
ES2183804T3 (es) 2003-04-01
DE69232776T2 (de) 2003-04-30
ATE224393T1 (de) 2002-10-15
DE69232776D1 (de) 2002-10-24

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Legal Events

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ELJ Ceased due to non-payment of the annual fee