ATA266689A - Verfahren zur herstellung von (s)-alpha-ethyl-2- oxo-1-pyrrolidinacetamid - Google Patents

Verfahren zur herstellung von (s)-alpha-ethyl-2- oxo-1-pyrrolidinacetamid

Info

Publication number: ATA266689A
Authority: AT; Austria
Prior art keywords: oxo; alpha; ethyl; producing; pyrrolidine acetamide
Prior art date: 1988-11-23

Application number

AT892666A

Other languages

English (en)

Other versions

AT392781B (de

Original Assignee

Ucb Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-23

Filing date

1989-11-22

Publication date

1990-11-15

1989-11-22 Application filed by Ucb Sa filed Critical Ucb Sa

1990-11-15 Publication of ATA266689A publication Critical patent/ATA266689A/de

1991-06-10 Application granted granted Critical

1991-06-10 Publication of AT392781B publication Critical patent/AT392781B/de

Links

HPHUVLMMVZITSG-LURJTMIESA-N levetiracetam Chemical compound CC[C@@H](C(N)=O)N1CCCC1=O HPHUVLMMVZITSG-LURJTMIESA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pyrrole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT2666/89A 1988-11-23 1989-11-22 Verfahren zur herstellung von (s)-alpha-ethyl-2- oxo-1-pyrrolidinacetamid AT392781B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888827389A GB8827389D0 (en)	1988-11-23	1988-11-23	Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide

Publications (2)

Publication Number	Publication Date
ATA266689A true ATA266689A (de)	1990-11-15
AT392781B AT392781B (de)	1991-06-10

Family

ID=10647345

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT2666/89A AT392781B (de)	1988-11-23	1989-11-22	Verfahren zur herstellung von (s)-alpha-ethyl-2- oxo-1-pyrrolidinacetamid

Country Status (17)

Country	Link
KR (1)	KR0157610B1 (de)
CN (1)	CN1020604C (de)
AT (1)	AT392781B (de)
BG (1)	BG51041A3 (de)
CY (1)	CY1672A (de)
ES (1)	ES2023532A6 (de)
FI (1)	FI91961C (de)
GB (2)	GB8827389D0 (de)
GR (1)	GR1000719B (de)
HK (1)	HK102492A (de)
HU (1)	HU204508B (de)
NO (1)	NO173823C (de)
PH (1)	PH26332A (de)
PL (1)	PL161781B1 (de)
PT (1)	PT92365B (de)
RU (1)	RU1797607C (de)
SG (1)	SG89392G (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9319732D0 (en)	1993-09-24	1993-11-10	Ucb Sa	Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
US6107492A (en) *	1998-05-08	2000-08-22	Ucb, S.A.	Process for the preparation of levetiracetam
AR026610A1 (es)	1999-12-01	2003-02-19	Ucb Sa	Un derivado pirrolidinacetamida solo o en combinacion para tratamiento de desordenes del sistema nervioso central
GB0004297D0 (en)	2000-02-23	2000-04-12	Ucb Sa	2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
RU2216322C1 (ru) *	2002-02-28	2003-11-20	Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации"	Средство, обладающее антиишемической, гипотензивной, противоаритмической и ноотропной активностью
CN1802352A (zh) *	2003-02-03	2006-07-12	特瓦制药工业有限公司	制备左乙拉西坦的方法
ES2214147B1 (es) *	2003-02-28	2005-10-01	Farma-Lepori S.A.	Procedimiento de obtencion de un agente antiepileptico.
WO2005028435A1 (en) *	2003-09-24	2005-03-31	Ucb, S.A.	Process for preparing 2-oxo-1-pyrrolidine derivatives
CA2488325C (en)	2004-11-22	2010-08-24	Apotex Pharmachem Inc.	Improved process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide
US8178533B2 (en)	2005-06-01	2012-05-15	Ucb Pharma, S.A.	2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
US8338621B2 (en)	2005-12-21	2012-12-25	Ucb S.A.	Process for the preparation of 2-oxo-1-pyrrolidine derivatives
WO2009050735A1 (en) *	2007-10-15	2009-04-23	Lupin Limited	A novel polymorph of levetiracetam and a process for its preparation
EP2147911A1 (de)	2008-07-24	2010-01-27	ZaCh System S.p.A.	Verfahren zur Herstellung von Levetiracetam
US7939676B2 (en)	2009-09-17	2011-05-10	Zach System S.P.A.	Process for the preparation of levetiracetam
MX386697B (es)	2014-01-21	2025-03-19	Janssen Pharmaceutica Nv	Combinaciones que comprenden agonistas ortostericos o moduladores alostericos positivos del receptor glutamatergico metabotropico de subtipo 2 y su uso
ME03518B (de)	2014-01-21	2020-04-20	Janssen Pharmaceutica Nv	Kombinationen mit positiven allosterischen modulatoren von metabotropem glutamatergen rezeptor vom subtyp 2 und deren verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1309692A (en) *	1970-02-13	1973-03-14	Ucb Sa	N-substituted lactams
GB8412357D0 (en) *	1984-05-15	1984-06-20	Ucb Sa	Pharmaceutical composition
GB8412358D0 (en) *	1984-05-15	1984-06-20	Ucb Sa	Pharmaceutical composition

1988
- 1988-11-23 GB GB888827389A patent/GB8827389D0/en active Pending
1989
- 1989-11-20 GR GR890100769A patent/GR1000719B/el not_active IP Right Cessation
- 1989-11-20 BG BG090398A patent/BG51041A3/bg unknown
- 1989-11-21 GB GB8926244A patent/GB2225322B/en not_active Expired - Lifetime
- 1989-11-21 PT PT92365A patent/PT92365B/pt not_active IP Right Cessation
- 1989-11-22 RU SU4742434A patent/RU1797607C/ru active
- 1989-11-22 CN CN89108764A patent/CN1020604C/zh not_active Expired - Fee Related
- 1989-11-22 ES ES8903978A patent/ES2023532A6/es not_active Expired - Lifetime
- 1989-11-22 HU HU896132A patent/HU204508B/hu not_active IP Right Cessation
- 1989-11-22 PL PL89282413A patent/PL161781B1/pl unknown
- 1989-11-22 FI FI895562A patent/FI91961C/fi active IP Right Grant
- 1989-11-22 AT AT2666/89A patent/AT392781B/de not_active IP Right Cessation
- 1989-11-22 NO NO894649A patent/NO173823C/no unknown
- 1989-11-23 KR KR1019890017038A patent/KR0157610B1/ko not_active Expired - Fee Related
- 1989-11-23 PH PH39568A patent/PH26332A/en unknown
1992
- 1992-09-05 SG SG893/92A patent/SG89392G/en unknown
- 1992-12-17 HK HK1024/92A patent/HK102492A/xx not_active IP Right Cessation
1993
- 1993-05-14 CY CY1672A patent/CY1672A/en unknown

Also Published As

Publication number	Publication date
RU1797607C (ru)	1993-02-23
GB2225322A (en)	1990-05-30
CN1020604C (zh)	1993-05-12
GB2225322B (en)	1992-03-25
PT92365A (pt)	1990-05-31
HUT53072A (en)	1990-09-28
NO173823C (no)	1994-02-09
HU204508B (en)	1992-01-28
PL161781B1 (en)	1993-07-30
FI895562A0 (fi)	1989-11-22
BG51041A3 (bg)	1993-01-15
CY1672A (en)	1993-05-14
PT92365B (pt)	1995-07-18
GR890100769A (en)	1990-12-31
GR1000719B (el)	1992-11-23
GB8926244D0 (en)	1990-01-10
AT392781B (de)	1991-06-10
CN1042904A (zh)	1990-06-13
ES2023532A6 (es)	1992-01-16
SG89392G (en)	1992-12-04
GB8827389D0 (en)	1988-12-29
FI91961C (fi)	1994-09-12
HK102492A (en)	1992-12-24
KR900007797A (ko)	1990-06-02
KR0157610B1 (ko)	1998-11-16
HU896132D0 (en)	1990-02-28
FI91961B (fi)	1994-05-31
NO894649D0 (no)	1989-11-22
NO894649L (no)	1990-05-25
PH26332A (en)	1992-04-29
NO173823B (no)	1993-11-01

Legal Events

Date	Code	Title	Description
2008-07-15	ELJ	Ceased due to non-payment of the annual fee

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