ATA29687A - Verfahren zur herstellung von neuen trifluormethyl substituierten tetracyclischen chinazolinonen und ihrer saeureadditionssalze - Google Patents

Verfahren zur herstellung von neuen trifluormethyl substituierten tetracyclischen chinazolinonen und ihrer saeureadditionssalze

Info

Publication number: ATA29687A
Authority: AT; Austria
Prior art keywords: chinazolinones; trifluormethyl; acid addition; addition salts; producing new
Prior art date: 1986-02-13

Application number

AT0029687A

Other languages

English (en)

Other versions

AT390062B (de

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-02-13

Filing date

1987-02-12

Publication date

1989-08-15

1987-02-12 Application filed by Sandoz Ag filed Critical Sandoz Ag

1989-08-15 Publication of ATA29687A publication Critical patent/ATA29687A/de

1990-03-12 Application granted granted Critical

1990-03-12 Publication of AT390062B publication Critical patent/AT390062B/de

Links

239000002253 acid Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT0029687A 1986-02-13 1987-02-12 Verfahren zur herstellung von neuen trifluormethyl substituierten tetracyclischen chinazolinonen und ihrer saeureadditionssalze AT390062B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/829,594 US4760065A (en)	1986-02-13	1986-02-13	Trifluoromethyl substituted tetracyclic quinazolin-ones having tranquilizing activity

Publications (2)

Publication Number	Publication Date
ATA29687A true ATA29687A (de)	1989-08-15
AT390062B AT390062B (de)	1990-03-12

Family

ID=25254954

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0029687A AT390062B (de)	1986-02-13	1987-02-12	Verfahren zur herstellung von neuen trifluormethyl substituierten tetracyclischen chinazolinonen und ihrer saeureadditionssalze

Country Status (22)

Country	Link
US (1)	US4760065A (de)
JP (1)	JPS62223183A (de)
KR (1)	KR870007900A (de)
AT (1)	AT390062B (de)
AU (1)	AU597936B2 (de)
BE (1)	BE1002099A3 (de)
CH (1)	CH671019A5 (de)
DE (1)	DE3702943A1 (de)
DK (1)	DK69787A (de)
ES (1)	ES2004215A6 (de)
FI (1)	FI870510L (de)
FR (1)	FR2601013A1 (de)
GB (1)	GB2186574B (de)
GR (1)	GR870232B (de)
HU (1)	HU198932B (de)
IL (1)	IL81536A0 (de)
IT (1)	IT1216790B (de)
LU (1)	LU86769A1 (de)
NL (1)	NL8700233A (de)
NZ (1)	NZ219242A (de)
SE (1)	SE8700566L (de)
ZA (1)	ZA871077B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH06509576A (ja) *	1991-07-29	1994-10-27	ワーナー−ランバート・コンパニー	アセチルコリンエステラーゼ阻害剤としてのキナゾリン誘導体
US6133002A (en) *	1997-09-25	2000-10-17	Dsm N.V.	Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives
EP2447239A1 (de) *	2010-10-29	2012-05-02	Saltigo GmbH	Kupfer-katalysiertes Verfahren zur Herstellung von substituiertem oder nichtsubstituiertem trifluormethyliertem Aryl und Heteroarylverbindungen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3280117A (en) *	1964-04-20	1966-10-18	Sandoz Ag	Tricyclic quinazolinones
US3598823A (en) *	1969-05-28	1971-08-10	Sandoz Ag	Tricyclic quinazolinones
US3772230A (en) *	1969-05-28	1973-11-13	Sandoz Ag	Polyhydro-imidazo(1,5-a)pyrimidine-3(2h)-thione and pyrido(1,2-c)pyrimidine-1-thione
US3631046A (en) *	1969-05-28	1971-12-28	Sandoz Ag	Tetracyclic quinazolin-ones
US4000275A (en) *	1969-11-24	1976-12-28	Eli Lilly And Company	Immunosuppressants
BE760013A (fr) *	1969-12-18	1971-06-08	Smith Kline French Lab	Imidazo et pyrimido -(2,1-b)quinazolines, leurs procedes de preparationet compositions pharmaceutiques en contenant
US3868372A (en) *	1971-07-09	1975-02-25	Sandoz Ag	Organomercapto-substituted polyhydro imidazo{8 1,5-a{9 pyridenes and pyride{8 1,2-c{9 pyrimidines
US3963720A (en) *	1972-10-27	1976-06-15	Sandoz, Inc.	Tetracyclic imidazo [2,1-b] quinazolinone derivatives
FR2512674B1 (fr) *	1981-09-16	1986-01-10	Sandoz Sa	Nouveaux derives tricycliques de la quinazolinone, leur preparation et medicaments contenant ces derives
US4452787A (en) *	1981-09-16	1984-06-05	Sandoz, Inc.	1-Substituted tricyclic quinazolinones having biological activity as tranquilizers
PH17745A (en) *	1981-09-16	1984-11-27	Sandoz Ag	Trifluoromethyl substituted tricyclic quinazolinones
PH19788A (en) *	1981-09-16	1986-07-02	Sandoz Ag	1-substituted tricyclic quinazolinones,pharmaceutical composition containing same and method of use thereof

1986
- 1986-02-13 US US06/829,594 patent/US4760065A/en not_active Expired - Fee Related
1987
- 1987-01-30 NL NL8700233A patent/NL8700233A/nl not_active Application Discontinuation
- 1987-01-30 CH CH346/87A patent/CH671019A5/de not_active IP Right Cessation
- 1987-01-30 HU HU87305A patent/HU198932B/hu not_active IP Right Cessation
- 1987-01-31 DE DE19873702943 patent/DE3702943A1/de not_active Withdrawn
- 1987-02-09 FI FI870510A patent/FI870510L/fi not_active Application Discontinuation
- 1987-02-09 FR FR8701669A patent/FR2601013A1/fr active Pending
- 1987-02-10 GB GB8702938A patent/GB2186574B/en not_active Expired - Lifetime
- 1987-02-11 NZ NZ219242A patent/NZ219242A/en unknown
- 1987-02-11 GR GR870232A patent/GR870232B/el unknown
- 1987-02-11 ES ES8700334A patent/ES2004215A6/es not_active Expired
- 1987-02-11 AU AU68694/87A patent/AU597936B2/en not_active Ceased
- 1987-02-11 DK DK069787A patent/DK69787A/da not_active Application Discontinuation
- 1987-02-11 IL IL81536A patent/IL81536A0/xx unknown
- 1987-02-12 BE BE8700112A patent/BE1002099A3/fr active
- 1987-02-12 AT AT0029687A patent/AT390062B/de not_active IP Right Cessation
- 1987-02-12 KR KR870001150A patent/KR870007900A/ko not_active Withdrawn
- 1987-02-12 LU LU86769A patent/LU86769A1/fr unknown
- 1987-02-12 SE SE8700566A patent/SE8700566L/xx not_active Application Discontinuation
- 1987-02-12 IT IT8747634A patent/IT1216790B/it active
- 1987-02-12 JP JP62028370A patent/JPS62223183A/ja active Pending
- 1987-02-13 ZA ZA871077A patent/ZA871077B/xx unknown

Also Published As

Publication number	Publication date
KR870007900A (ko)	1987-09-22
DE3702943A1 (de)	1987-08-20
IT8747634A0 (it)	1987-02-12
HUT43607A (en)	1987-11-30
LU86769A1 (fr)	1987-09-15
FI870510A7 (fi)	1987-08-14
NL8700233A (nl)	1987-09-01
AT390062B (de)	1990-03-12
SE8700566L (sv)	1987-08-14
ZA871077B (en)	1988-09-28
IL81536A0 (en)	1987-09-16
IT1216790B (it)	1990-03-14
AU597936B2 (en)	1990-06-14
AU6869487A (en)	1987-08-20
ES2004215A6 (es)	1988-12-16
FI870510A0 (fi)	1987-02-09
GB2186574A (en)	1987-08-19
NZ219242A (en)	1990-04-26
SE8700566D0 (sv)	1987-02-12
DK69787A (da)	1987-08-14
HU198932B (en)	1989-12-28
GB2186574B (en)	1990-03-28
BE1002099A3 (fr)	1990-07-03
GR870232B (en)	1987-06-12
FR2601013A1 (fr)	1988-01-08
CH671019A5 (de)	1989-07-31
DK69787D0 (da)	1987-02-11
US4760065A (en)	1988-07-26
FI870510L (fi)	1987-08-14
JPS62223183A (ja)	1987-10-01
GB8702938D0 (en)	1987-03-18

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Legal Events

Date	Code	Title
1988-01-15	UEP	Publication of translation of european patent specification
1991-05-15	ELJ	Ceased due to non-payment of the annual fee
1996-09-15	REN	Ceased due to non-payment of the annual fee