ATA45677A - PROCESS FOR THE PREPARATION OF 4-DESACETOXY- -VINBLASTIN AND ITS ACID ADDITION SALTS - Google Patents

PROCESS FOR THE PREPARATION OF 4-DESACETOXY- -VINBLASTIN AND ITS ACID ADDITION SALTS

Info

Publication number: ATA45677A
Authority: AT; Austria
Prior art keywords: desacetoxy; vinblastin; preparation; acid addition; addition salts
Prior art date: 1976-02-13

Application number

AT45677A

Other languages

German (de)

Other versions

AT357692B (en

Inventor

Karola Jovanovics

Lajos Chem Ing Dancsi

Sandor Dr Eckhardt

Csaba Lorencz

Janos Dr Sugar

Zsuzsa Dr Relle

Kalman Szasz

Jozsef Chem Ing Tamas

Aron Chem Ing Szoellosy

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-02-13

Filing date

1977-01-26

Publication date

1979-12-15

1977-01-26 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1979-12-15 Publication of ATA45677A publication Critical patent/ATA45677A/en

1980-07-25 Application granted granted Critical

1980-07-25 Publication of AT357692B publication Critical patent/AT357692B/en

Links

LVINNLJJGRZGKQ-VMJLQBTBSA-N 4-Desacetoxyvinblastine Natural products CC[C@]1(O)C[C@@H]2CN(CC[C@H]3[C@@H](Nc4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@H]7[C@](O)(C[C@]8(CC)C=CCN9CC[C@]67[C@H]89)C(=O)OC)C1 LVINNLJJGRZGKQ-VMJLQBTBSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Plant Substances (AREA)

AT45677A 1976-02-13 1977-01-26 METHOD FOR PRODUCING 4-DESACETOXY- -VINBLASTIN AND ITS ACID ADDITION SALTS AT357692B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU76RI585A HU173379B (en)	1976-02-13	1976-02-13	Process for producing 4-deacetoxy-vinblastine and acid additional salts thereof

Publications (2)

Publication Number	Publication Date
ATA45677A true ATA45677A (en)	1979-12-15
AT357692B AT357692B (en)	1980-07-25

Family

ID=11000994

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT45677A AT357692B (en)	1976-02-13	1977-01-26	METHOD FOR PRODUCING 4-DESACETOXY- -VINBLASTIN AND ITS ACID ADDITION SALTS

Country Status (8)

Country	Link
JP (1)	JPS52100498A (en)
AT (1)	AT357692B (en)
BE (1)	BE851345A (en)
DE (1)	DE2704316A1 (en)
FR (1)	FR2340952A1 (en)
GB (1)	GB1561226A (en)
HU (1)	HU173379B (en)
SU (1)	SU667140A3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2894966B1 (en) *	2005-12-20	2008-03-14	Pierre Fabre Medicament Sa	NEW CRYSTALLINE FORM OF VINFLUNINE

1976
- 1976-02-13 HU HU76RI585A patent/HU173379B/en not_active IP Right Cessation
1977
- 1977-01-26 AT AT45677A patent/AT357692B/en not_active IP Right Cessation
- 1977-02-02 DE DE19772704316 patent/DE2704316A1/en not_active Ceased
- 1977-02-10 SU SU772450355A patent/SU667140A3/en active
- 1977-02-10 JP JP1313177A patent/JPS52100498A/en active Granted
- 1977-02-10 GB GB5555/77A patent/GB1561226A/en not_active Expired
- 1977-02-10 FR FR7703771A patent/FR2340952A1/en active Granted
- 1977-02-11 BE BE174869A patent/BE851345A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2340952B1 (en)	1980-02-01
GB1561226A (en)	1980-02-13
HU173379B (en)	1979-04-28
BE851345A (en)	1977-05-31
JPS6228155B2 (en)	1987-06-18
JPS52100498A (en)	1977-08-23
DE2704316A1 (en)	1977-08-18
FR2340952A1 (en)	1977-09-09
SU667140A3 (en)	1979-06-05
AT357692B (en)	1980-07-25

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Legal Events

Date	Code	Title	Description
1985-09-15	ELJ	Ceased due to non-payment of the annual fee
1997-01-15	EEIH	Change in the person of patent owner