ATA493176A - Verfahren zur herstellung des neuen 4-imino-1.3-diazabicyclo- (3.1.0)-hexan-2-on und seiner physiologisch vertraglichen salze - Google Patents

Verfahren zur herstellung des neuen 4-imino-1.3-diazabicyclo- (3.1.0)-hexan-2-on und seiner physiologisch vertraglichen salze

Info

Publication number: ATA493176A
Authority: AT; Austria
Prior art keywords: hexan; diazabicyclo; imino; producing; new
Prior art date: 1975-07-08

Application number

AT493176A

Other languages

English (en)

Other versions

AT345846B (de

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-07-08

Filing date

1976-07-06

Publication date

1978-02-15

1976-07-06 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1978-02-15 Publication of ATA493176A publication Critical patent/ATA493176A/de

1978-10-10 Application granted granted Critical

1978-10-10 Publication of AT345846B publication Critical patent/AT345846B/de

Links

BIXBBIPTYBJTRY-UHFFFAOYSA-N imexon Chemical compound NC1=NC(=O)N2CC12 BIXBBIPTYBJTRY-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Color Printing (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT493176A 1975-07-08 1976-07-06 Verfahren zur herstellung des neuen 4-imino- 1.3-diazabicyclo- (3.1.0)-hexan-2-on und seiner physiologisch vertraeglichen salze AT345846B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19752530398 DE2530398A1 (de)	1975-07-08	1975-07-08	Organische verbindung

Publications (2)

Publication Number	Publication Date
ATA493176A true ATA493176A (de)	1978-02-15
AT345846B AT345846B (de)	1978-10-10

Family

ID=5950951

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT493176A AT345846B (de)	1975-07-08	1976-07-06	Verfahren zur herstellung des neuen 4-imino- 1.3-diazabicyclo- (3.1.0)-hexan-2-on und seiner physiologisch vertraeglichen salze

Country Status (26)

Country	Link
US (1)	US4083987A (de)
JP (1)	JPS5210290A (de)
AR (1)	AR208802A1 (de)
AT (1)	AT345846B (de)
AU (1)	AU497292B2 (de)
BE (1)	BE843803A (de)
CA (1)	CA1069125A (de)
CH (1)	CH598259A5 (de)
CS (1)	CS198195B2 (de)
DD (1)	DD125079A5 (de)
DE (1)	DE2530398A1 (de)
DK (1)	DK139752C (de)
ES (1)	ES449597A1 (de)
FI (1)	FI59250C (de)
FR (1)	FR2316945A1 (de)
GB (1)	GB1490486A (de)
HU (1)	HU170252B (de)
IL (1)	IL49964A (de)
IN (1)	IN146367B (de)
LU (1)	LU75314A1 (de)
NL (1)	NL160564C (de)
PL (1)	PL98937B1 (de)
PT (1)	PT65327B (de)
SE (1)	SE409864B (de)
SU (1)	SU604482A3 (de)
ZA (1)	ZA763977B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3825667A1 (de) *	1988-07-28	1990-03-15	Boehringer Mannheim Gmbh	Verwendung von imexon als immunsuppressivum
US5369119A (en) *	1988-07-28	1994-11-29	Boehringer Mannheim Gmbh	Use of imexon as an immune suppressive and pharmaceutical compositions containing imexon
DE3844655A1 (de) *	1988-07-28	1990-05-17	Boehringer Mannheim Gmbh	Verwendung von imexon als immunsuppressivum
DE3841879A1 (de) *	1988-12-13	1990-06-21	Boehringer Mannheim Gmbh	Neue imidazolidin-derivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US20030129222A1 (en) *	2000-11-21	2003-07-10	Gabriel Lopez-Berestein	Liposomal imexon
CA2431947A1 (en) *	2000-11-21	2002-05-30	Gabriel Lopez-Berestein	Composition comprising an imexon or derivatives thereof and lipids
US6476236B1 (en) *	2001-11-26	2002-11-05	The Arizona Board Of Regents	Synthesis of 2-cyanoaziridine-1-carboxamide
WO2006042662A1 (de) *	2004-10-15	2006-04-27	Heidelberg Pharma Gmbh	Parenterale darreichungsformen von imexon sowie verfahren zu deren herstellung
WO2008045686A2 (en) *	2006-10-12	2008-04-17	The Arizona Board Of Regents On Behalf Of The University Of Arizona	Enantiomerically enriched iminopyrrolidone azirdine compositions

1975
- 1975-07-08 DE DE19752530398 patent/DE2530398A1/de not_active Withdrawn
1976
- 1976-05-26 US US05/690,340 patent/US4083987A/en not_active Expired - Lifetime
- 1976-06-28 CA CA255,790A patent/CA1069125A/en not_active Expired
- 1976-06-29 DD DD193619A patent/DD125079A5/xx unknown
- 1976-07-01 DK DK297176A patent/DK139752C/da active
- 1976-07-02 GB GB27657/76A patent/GB1490486A/en not_active Expired
- 1976-07-02 AR AR263845A patent/AR208802A1/es active
- 1976-07-02 IL IL49964A patent/IL49964A/en unknown
- 1976-07-05 ZA ZA763977A patent/ZA763977B/xx unknown
- 1976-07-05 CS CS764432A patent/CS198195B2/cs unknown
- 1976-07-05 HU HUBO1622A patent/HU170252B/hu unknown
- 1976-07-05 BE BE168650A patent/BE843803A/xx unknown
- 1976-07-05 AU AU15596/76A patent/AU497292B2/en not_active Expired
- 1976-07-05 FI FI761958A patent/FI59250C/fi not_active IP Right Cessation
- 1976-07-05 SE SE7607675A patent/SE409864B/xx unknown
- 1976-07-05 CH CH859076A patent/CH598259A5/xx not_active IP Right Cessation
- 1976-07-06 ES ES449597A patent/ES449597A1/es not_active Expired
- 1976-07-06 NL NL7607429.A patent/NL160564C/xx not_active IP Right Cessation
- 1976-07-06 LU LU75314A patent/LU75314A1/xx unknown
- 1976-07-06 AT AT493176A patent/AT345846B/de not_active IP Right Cessation
- 1976-07-07 PL PL1976190969A patent/PL98937B1/pl unknown
- 1976-07-07 PT PT65327A patent/PT65327B/de unknown
- 1976-07-07 FR FR7620739A patent/FR2316945A1/fr active Granted
- 1976-07-08 SU SU762379563A patent/SU604482A3/ru active
- 1976-07-08 JP JP51081456A patent/JPS5210290A/ja active Granted
1977
- 1977-07-01 IN IN992/CAL/77A patent/IN146367B/en unknown

Also Published As

Publication number	Publication date
NL7607429A (nl)	1977-01-11
FI761958A7 (de)	1977-01-09
CH598259A5 (de)	1978-04-28
JPS543876B2 (de)	1979-02-27
PT65327A (de)	1976-08-01
AU497292B2 (en)	1978-12-07
FR2316945A1 (fr)	1977-02-04
NL160564B (nl)	1979-06-15
SE409864B (sv)	1979-09-10
AR208802A1 (es)	1977-02-28
US4083987A (en)	1978-04-11
DE2530398A1 (de)	1977-01-27
CS198195B2 (en)	1980-05-30
FI59250C (fi)	1981-07-10
DK139752B (da)	1979-04-09
CA1069125A (en)	1980-01-01
AU1559676A (en)	1978-01-12
IN146367B (de)	1979-05-12
SU604482A3 (ru)	1978-04-25
IL49964A (en)	1978-07-31
ZA763977B (en)	1977-06-29
BE843803A (fr)	1977-01-05
HU170252B (de)	1977-05-28
PT65327B (de)	1978-01-05
LU75314A1 (de)	1977-02-24
JPS5210290A (en)	1977-01-26
PL98937B1 (pl)	1978-05-31
AT345846B (de)	1978-10-10
DK139752C (da)	1979-09-17
FR2316945B1 (de)	1978-12-15
DK297176A (da)	1977-01-09
IL49964A0 (en)	1976-09-30
SE7607675L (sv)	1977-01-09
ES449597A1 (es)	1977-08-01
FI59250B (fi)	1981-03-31
DD125079A5 (de)	1977-03-30
GB1490486A (en)	1977-11-02
NL160564C (nl)	1979-11-15

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Legal Events

Date	Code	Title	Description
1984-11-15	ELJ	Ceased due to non-payment of the annual fee