ATA582978A - Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen - Google Patents

Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen

Info

Publication number: ATA582978A
Authority: AT; Austria
Prior art keywords: razemats; hydroxy; salts; optically active; active forms
Prior art date: 1977-08-12

Application number

AT582978A

Other languages

English (en)

Other versions

AT364831B (de

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-08-12

Filing date

1978-08-10

Publication date

1981-04-15

1978-01-18 Priority claimed from DE19782801953 external-priority patent/DE2801953A1/de

1978-08-10 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1980-11-12 Priority to AT556180A priority Critical patent/AT375650B/de

1981-04-15 Publication of ATA582978A publication Critical patent/ATA582978A/de

1981-11-25 Application granted granted Critical

1981-11-25 Publication of AT364831B publication Critical patent/AT364831B/de

Links

CPBGGIHYAYWNDD-UHFFFAOYSA-N 4-hydroxy-1,3-dihydrobenzimidazol-2-one Chemical class OC1=CC=CC2=C1NC(=O)N2 CPBGGIHYAYWNDD-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT0582978A 1977-08-12 1978-08-10 Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen AT364831B (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AT556180A AT375650B (de)	1977-08-12	1980-11-12	Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2736295		1977-08-12
DE19782801953 DE2801953A1 (de)	1978-01-18	1978-01-18	4-hydroxy-2-benzimidazolinon-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number	Publication Date
ATA582978A true ATA582978A (de)	1981-04-15
AT364831B AT364831B (de)	1981-11-25

Family

ID=25772515

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0582978A AT364831B (de)	1977-08-12	1978-08-10	Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen

Country Status (14)

Country	Link
US (1)	US4367235A (de)
EP (1)	EP0000784B1 (de)
JP (1)	JPS5432467A (de)
AT (1)	AT364831B (de)
AU (1)	AU3888578A (de)
CA (1)	CA1108619A (de)
DD (1)	DD137584A5 (de)
DE (1)	DE2860981D1 (de)
DK (1)	DK355378A (de)
ES (1)	ES472435A1 (de)
FI (1)	FI782452A7 (de)
IL (1)	IL55315A0 (de)
IT (1)	IT7826640A0 (de)
PT (1)	PT68404A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0178413A1 (de) *	1984-08-17	1986-04-23	Beecham Group Plc	Benzimidazole
US4554287A (en) *	1984-09-12	1985-11-19	Smithkline Beckman Corporation	Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones
JPS63156809A (ja) *	1986-12-19	1988-06-29	Shin Etsu Chem Co Ltd	塩化ビニル系重合体の製造方法
CA2085844A1 (en) *	1991-12-27	1993-06-28	Nobuyuki Hamanaka	Fused benzeneoxyacetic acid derivatives
WO1995004047A1 (en) *	1993-07-31	1995-02-09	Smithkline Beecham Plc	2-benzoheterocyclyloxy or thiopropanolamine derivatives with adreno receptor agonist activity
ZA967892B (en) *	1995-09-21	1998-03-18	Lilly Co Eli	Selective β3 adrenergic agonists.
US6075040A (en) *	1996-09-05	2000-06-13	Eli Lilly And Company	Selective β3 adrenergic agonists
EP0827746B1 (de)	1996-09-05	2002-04-03	Eli Lilly And Company	Carbazolanaloge als selektive beta3-adrenergische Agonisten
CO5011072A1 (es)	1997-12-05	2001-02-28	Lilly Co Eli	Etanolaminas pirazinil substituidas como agfonistas de los receptores
CN103445428A (zh) *	2012-05-28	2013-12-18	苏州科羽电子技术服务有限公司	一种车座手提袋

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4081447A (en) *	1975-04-09	1978-03-28	Abbott Laboratories	5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH624395A5 (de) *	1976-01-08	1981-07-31	Ciba Geigy Ag

1978
- 1978-07-31 CA CA308,433A patent/CA1108619A/en not_active Expired
- 1978-08-08 IL IL7855315A patent/IL55315A0/xx unknown
- 1978-08-08 PT PT68404A patent/PT68404A/de unknown
- 1978-08-08 ES ES472435A patent/ES472435A1/es not_active Expired
- 1978-08-09 IT IT7826640A patent/IT7826640A0/it unknown
- 1978-08-09 DD DD78207192A patent/DD137584A5/de unknown
- 1978-08-09 EP EP78100633A patent/EP0000784B1/de not_active Expired
- 1978-08-09 DE DE7878100633T patent/DE2860981D1/de not_active Expired
- 1978-08-10 AT AT0582978A patent/AT364831B/de not_active IP Right Cessation
- 1978-08-10 FI FI782452A patent/FI782452A7/fi not_active Application Discontinuation
- 1978-08-11 DK DK355378A patent/DK355378A/da not_active Application Discontinuation
- 1978-08-11 JP JP9811278A patent/JPS5432467A/ja active Pending
- 1978-08-14 AU AU38885/78A patent/AU3888578A/en active Pending
1980
- 1980-07-18 US US06/171,940 patent/US4367235A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AT364831B (de)	1981-11-25
DK355378A (da)	1979-02-13
FI782452A7 (fi)	1979-02-13
AU3888578A (en)	1980-02-21
ES472435A1 (es)	1979-04-16
US4367235A (en)	1983-01-04
CA1108619A (en)	1981-09-08
IL55315A0 (en)	1978-10-31
DD137584A5 (de)	1979-09-12
EP0000784A1 (de)	1979-02-21
DE2860981D1 (en)	1981-11-19
JPS5432467A (en)	1979-03-09
EP0000784B1 (de)	1981-08-26
IT7826640A0 (it)	1978-08-09
PT68404A (de)	1978-09-01

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Legal Events

Date	Code	Title	Description
1987-01-15	ELJ	Ceased due to non-payment of the annual fee