ATE100085T1 - Salze des (2-(2-pyridyl)ethyl)-methylamins. - Google Patents
Salze des (2-(2-pyridyl)ethyl)-methylamins.Info
- Publication number
- ATE100085T1 ATE100085T1 AT90108352T AT90108352T ATE100085T1 AT E100085 T1 ATE100085 T1 AT E100085T1 AT 90108352 T AT90108352 T AT 90108352T AT 90108352 T AT90108352 T AT 90108352T AT E100085 T1 ATE100085 T1 AT E100085T1
- Authority
- AT
- Austria
- Prior art keywords
- methylamine
- pyridyl
- salts
- ethyl
- acids
- Prior art date
Links
- UUQMNUMQCIQDMZ-UHFFFAOYSA-N betahistine Chemical class CNCCC1=CC=CC=N1 UUQMNUMQCIQDMZ-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- -1 fumaric Chemical class 0.000 abstract 1
- 150000002691 malonic acids Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000002110 toxicologic effect Effects 0.000 abstract 1
- 231100000027 toxicology Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8920412A IT1229237B (it) | 1989-05-08 | 1989-05-08 | Sali di (2-(piridil)etil) metilammina |
| EP90108352A EP0397025B1 (de) | 1989-05-08 | 1990-05-03 | Salze des (2-(2-Pyridyl)ethyl)-methylamins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE100085T1 true ATE100085T1 (de) | 1994-01-15 |
Family
ID=11166541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90108352T ATE100085T1 (de) | 1989-05-08 | 1990-05-03 | Salze des (2-(2-pyridyl)ethyl)-methylamins. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0397025B1 (de) |
| AT (1) | ATE100085T1 (de) |
| DE (1) | DE69005892D1 (de) |
| IT (1) | IT1229237B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1493435B1 (de) | 2003-07-04 | 2008-05-14 | FARMACEUTICI FORMENTI S.p.A. | Betahistinezubereitungen mit kontrollierter Freisetzung |
| RU2308941C1 (ru) * | 2006-05-10 | 2007-10-27 | Открытое акционерное общество "Московское производственное химико-фармацевтическое объединение им. Н.А. Семашко" | Твердая лекарственная форма, обладающая гистаминоподобным действием, и способ ее получения |
| RU2340603C1 (ru) * | 2007-07-18 | 2008-12-10 | Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") | Способ получения солей 2-(2-метиламиноэтил)пиридина |
| CN102046170B (zh) | 2008-05-27 | 2012-11-28 | 墨尔本大学 | 治疗患有咽鼓管功能障碍的哺乳动物的方法 |
| WO2011139250A2 (en) * | 2010-05-04 | 2011-11-10 | Mahmut Bilgic | Water dispersible formulation |
| DE102012105528A1 (de) * | 2012-06-25 | 2014-01-02 | Hennig Arzneimittel Gmbh & Co. Kg | Arzneiform zur Freisetzung von Wirkstoffen |
| ES2969301T3 (es) * | 2017-02-02 | 2024-05-17 | Otolanum Ag | Composición intranasal que comprende betahistina |
| WO2026062705A1 (en) | 2024-09-23 | 2026-03-26 | Troikaa Pharmaceuticals Limited | Oromucosal liquid compositions of betahistine or its pharmaceutically acceptable salt(s) and processes for preparation thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3522244A (en) * | 1967-09-12 | 1970-07-28 | Unimed Inc | Salts of beta-(pyridyl alkyl) amines with 21 - hydroxy steroid polyvalent acid esters |
| GB1417029A (en) * | 1973-03-07 | 1975-12-10 | Pfizer Ltd | Quinazoline-derived amines |
| US4600710A (en) * | 1985-03-14 | 1986-07-15 | G. D. Searle & Co. | β-Adrenergic receptor agonist alkylaminoalkyl pyridinemethanol derivatives |
| US4728663A (en) * | 1986-01-13 | 1988-03-01 | American Cyanamid Company | N-[(1H-imidazol-1-yl)alkyl]benz[cd]-indol-2-amines and use in inhibiting thromboxane synthetase enzyme |
-
1989
- 1989-05-08 IT IT8920412A patent/IT1229237B/it active
-
1990
- 1990-05-03 DE DE90108352T patent/DE69005892D1/de not_active Expired - Lifetime
- 1990-05-03 EP EP90108352A patent/EP0397025B1/de not_active Expired - Lifetime
- 1990-05-03 AT AT90108352T patent/ATE100085T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0397025B1 (de) | 1994-01-12 |
| DE69005892D1 (de) | 1994-02-24 |
| IT8920412A0 (it) | 1989-05-08 |
| IT1229237B (it) | 1991-07-26 |
| EP0397025A1 (de) | 1990-11-14 |
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