ATE102025T1 - Nichtfestes augenarzneimittel und verfahren zur herstellung dieses arzneimittels. - Google Patents

Nichtfestes augenarzneimittel und verfahren zur herstellung dieses arzneimittels.

Info

Publication number
ATE102025T1
ATE102025T1 AT90311207T AT90311207T ATE102025T1 AT E102025 T1 ATE102025 T1 AT E102025T1 AT 90311207 T AT90311207 T AT 90311207T AT 90311207 T AT90311207 T AT 90311207T AT E102025 T1 ATE102025 T1 AT E102025T1
Authority
AT
Austria
Prior art keywords
medicinal product
solid
manufacture
dissolution
microparticles
Prior art date
Application number
AT90311207T
Other languages
English (en)
Inventor
Annouk Rozier
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE102025T1 publication Critical patent/ATE102025T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT90311207T 1989-10-17 1990-10-12 Nichtfestes augenarzneimittel und verfahren zur herstellung dieses arzneimittels. ATE102025T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8913533A FR2653018A1 (fr) 1989-10-17 1989-10-17 Composition ophtalmique non solide a base de microparticules de polymere contenant au moins un principe actif en suspension dans un milieu dispersant et procede de preparation de ladite composition.
EP90311207A EP0424042B1 (de) 1989-10-17 1990-10-12 Nichtfestes Augenarzneimittel und Verfahren zur Herstellung dieses Arzneimittels

Publications (1)

Publication Number Publication Date
ATE102025T1 true ATE102025T1 (de) 1994-03-15

Family

ID=9386462

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90311207T ATE102025T1 (de) 1989-10-17 1990-10-12 Nichtfestes augenarzneimittel und verfahren zur herstellung dieses arzneimittels.

Country Status (9)

Country Link
EP (1) EP0424042B1 (de)
JP (1) JPH03206031A (de)
AT (1) ATE102025T1 (de)
CA (1) CA2027607A1 (de)
DE (1) DE69007010T2 (de)
DK (1) DK0424042T3 (de)
ES (1) ES2062401T3 (de)
FR (1) FR2653018A1 (de)
IE (1) IE64044B1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
TW240160B (de) * 1992-06-30 1995-02-11 Senju Pharma Co
CA2101126A1 (en) * 1992-08-03 1994-02-04 Yasushi Morita Preparation for local treatment
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
CZ285636B6 (cs) * 1995-02-07 1999-10-13 Ústav Makromolekulární Chemie Av Čr Nové lékové formy pro farmaka aplikovaná v očním lékařství s prolongovanou účinností a způsob jejich výroby
CN1204922C (zh) * 2001-02-15 2005-06-08 株式会社三和化学研究所 新的眼科用组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions

Also Published As

Publication number Publication date
EP0424042A1 (de) 1991-04-24
EP0424042B1 (de) 1994-03-02
ES2062401T3 (es) 1994-12-16
DK0424042T3 (da) 1994-03-28
CA2027607A1 (en) 1991-04-18
IE64044B1 (en) 1995-06-28
DE69007010T2 (de) 1994-08-04
IE903712A1 (en) 1991-04-24
DE69007010D1 (de) 1994-04-07
JPH03206031A (ja) 1991-09-09
FR2653018A1 (fr) 1991-04-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee