ATE102071T1 - Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie. - Google Patents

Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie.

Info

Publication number
ATE102071T1
ATE102071T1 AT89118199T AT89118199T ATE102071T1 AT E102071 T1 ATE102071 T1 AT E102071T1 AT 89118199 T AT89118199 T AT 89118199T AT 89118199 T AT89118199 T AT 89118199T AT E102071 T1 ATE102071 T1 AT E102071T1
Authority
AT
Austria
Prior art keywords
laborable
removal
exchange chromatography
process chemicals
biological mixtures
Prior art date
Application number
AT89118199T
Other languages
English (en)
Inventor
Richard J Bonomo
Bernard Horowitz
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22971853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE102071(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Application granted granted Critical
Publication of ATE102071T1 publication Critical patent/ATE102071T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • External Artificial Organs (AREA)
  • Steroid Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AT89118199T 1988-10-07 1989-09-30 Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie. ATE102071T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/256,332 US5094960A (en) 1988-10-07 1988-10-07 Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
EP89118199A EP0366946B1 (de) 1988-10-07 1989-09-30 Entfernen von Verfahrenschemikalien aus labilen biologischen Gemischen durch hydrophobe Austauschchromatographie

Publications (1)

Publication Number Publication Date
ATE102071T1 true ATE102071T1 (de) 1994-03-15

Family

ID=22971853

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89118199T ATE102071T1 (de) 1988-10-07 1989-09-30 Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie.

Country Status (9)

Country Link
US (1) US5094960A (de)
EP (1) EP0366946B1 (de)
JP (1) JP2799747B2 (de)
KR (1) KR970007941B1 (de)
AT (1) ATE102071T1 (de)
AU (1) AU621148B2 (de)
CA (1) CA1337052C (de)
DE (1) DE68913422T2 (de)
ES (1) ES2051951T3 (de)

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DE4008852A1 (de) * 1990-03-20 1991-09-26 Octapharma Ag Verfahren zur herstellung von nicht-infektioesem blutplasma
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
EP0602173B1 (de) * 1991-09-05 1999-05-26 Baxter International Inc. Topischer fibrinogenkomplex
FR2690444B1 (fr) * 1992-04-22 1995-07-13 Rucheton Marcel Procede de preparation d'une solution d'albumine plasmatique purifiee.
AU667530B2 (en) * 1992-05-28 1996-03-28 New York Blood Center, Inc., The Removal of antibodies from blood-derived compositions while retaining coagulation factors
JPH06166634A (ja) * 1992-12-01 1994-06-14 Green Cross Corp:The プラスミノーゲン含有組成物の製造方法
DE4302163A1 (de) * 1993-01-27 1994-07-28 Thomae Gmbh Dr K Verfahren zur Reinigung von Proteinen und Peptiden
JPH09500015A (ja) * 1993-06-23 1997-01-07 ニューヨーク ブラッド センター，インコーポレイティド 血液のウィルス不活性化のためのシステム
US6319662B1 (en) 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid
JPH08257115A (ja) * 1995-03-20 1996-10-08 Kanegafuchi Chem Ind Co Ltd 腫瘍壊死因子の吸着剤および吸着除去方法
ES2337852T3 (es) * 1995-06-07 2010-04-29 Cerus Corporation Metodos y dispositivos para la eliminacion de psoralenos de productos sanguineos.
US6544727B1 (en) * 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
DE19544297A1 (de) 1995-11-28 1997-06-05 Behringwerke Ag Verfahren zur Entfernung von aromatischen Verbindungen aus produkthaltigen Lösungen
US5747639A (en) * 1996-03-06 1998-05-05 Amgen Boulder Inc. Use of hydrophobic interaction chromatography to purify polyethylene glycols
US20020115585A1 (en) * 1996-06-07 2002-08-22 Hei Derek J. Method and devices for the removal of psoralens from blood products
US5811403A (en) * 1996-09-30 1998-09-22 Vanderbilt University Polysaccharide toxin from Group B β-hemolytic Streptococcus (GBS) having improved purity
CA2276747C (en) * 1997-01-06 2004-04-13 Cerus Corporation Methods and devices for the reduction of small organic compounds from blood products
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US5952235A (en) * 1997-04-14 1999-09-14 Case Western Reserve University Detection of teratogen exposure
DE69826521T2 (de) 1998-01-06 2005-09-29 Cerus Corp., Concord Verfahren zum quenchen von pathogen-inaktivatoren in biologischen materialien
US7611831B2 (en) * 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US6495140B1 (en) 1998-01-12 2002-12-17 Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Process for the isolation, recovery and purification of non-polar extractives
AT408613B (de) 1998-06-17 2002-01-25 Immuno Ag Pharmazeutisches faktor vii-präparat
DE19834053A1 (de) * 1998-07-29 2000-03-30 Centeon Pharma Gmbh Verfahren und Mittel zur Sanatisierung von durch Viren verursachten Kontaminationen
IL136552A (en) 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration
RS50891B (sr) * 2003-02-13 2010-08-31 Octapharma Ag. Postupak za pripremanje rastvora albumina
EP1610445A4 (de) 2003-09-10 2006-01-04 Aisin Aw Co Einrichtung und verfahren zur herstellung einer rotierenden elektrischen maschine
US6881573B2 (en) * 2003-09-12 2005-04-19 Allan L. Louderback Augmented solvent/detergent method for inactivating enveloped and non-enveloped viruses
US20060234907A1 (en) * 2004-02-13 2006-10-19 Werner Gehringer Albumin solution and process for the production thereof
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
AU2005265960B8 (en) * 2004-06-29 2012-01-12 Reliance Life Sciences Pvt Ltd Process for improvement of virus-safe biological fluids
GB0423196D0 (en) * 2004-10-19 2004-11-24 Nat Blood Authority Method
CN101094692A (zh) * 2004-10-29 2007-12-26 塞鲁斯公司 用于红细胞灭活过程的改进的猝灭方法
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
EP1685852A1 (de) 2005-02-01 2006-08-02 Fondation pour la Recherche Diagnostique Set von Einwegbeuteln zur Virusinaktivierung von biologischen Fluids
WO2007054297A2 (de) * 2005-11-11 2007-05-18 Csl Behring Gmbh Verwendung hydrophober interaktionschromatographie zur virusabreichung
US8480889B2 (en) * 2006-04-27 2013-07-09 Agilent Technologies, Inc. Chromatographic stationary phase
US8333446B2 (en) 2006-05-30 2012-12-18 Lg Electronics Inc. Apparatus for preventing leakage of cooling air for refrigerator
US20080293623A1 (en) * 2007-04-30 2008-11-27 Nhs Blood And Transplant Enriched haptoglobin polymers for the treatment of disease
SG189745A1 (en) 2008-04-09 2013-05-31 Cerus Corp Improved quenching methods for red blood cell pathogen inactivation
CN102365262B (zh) * 2009-03-31 2014-09-17 3M创新有限公司 疏水单体、疏水衍生载体及其制备和使用方法
US9175281B2 (en) * 2010-11-16 2015-11-03 Cadila Healthcare Limited Process for the purification of tissue plasminogen activator
IL210162A0 (en) 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
WO2013023362A1 (zh) * 2011-08-16 2013-02-21 深圳市卫武光明生物制品有限公司 静注巨细胞病毒人免疫球蛋白及其制备方法
CH706420A1 (fr) * 2012-04-19 2013-10-31 Valerie Soulie Procédé d'inactivation virale d'un fluide biologique, dispositif et récipient pour la mise en œuvre d'un tel procédé.
EP2934603A1 (de) 2012-12-20 2015-10-28 Omrix Biopharmaceuticals Ltd. Inaktivierte virale biologische mischung
KR102271515B1 (ko) 2015-02-06 2021-07-05 광저우 바이오실 바이오테크 캄파니 리미티드 트롬빈의 제조 방법

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US4789545A (en) * 1986-03-31 1988-12-06 New York Blood Center, Inc. Removal of lipid soluble process chemicals from biological materials by extraction with naturally occurring oils or synthetic substitutes thereof
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US4894330A (en) * 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
US4909940A (en) 1987-12-30 1990-03-20 New York Blood Center, Inc. Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons

Also Published As

Publication number Publication date
AU621148B2 (en) 1992-03-05
US5094960A (en) 1992-03-10
KR900006010A (ko) 1990-05-07
DE68913422T2 (de) 1994-06-01
EP0366946B1 (de) 1994-03-02
AU4155989A (en) 1990-09-13
DE68913422D1 (de) 1994-04-07
KR970007941B1 (ko) 1997-05-19
ES2051951T3 (es) 1994-07-01
JPH02198561A (ja) 1990-08-07
CA1337052C (en) 1995-09-19
JP2799747B2 (ja) 1998-09-21
EP0366946A1 (de) 1990-05-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time